M. Kounnas

发表

Reductions in beta-amyloid concentrations in vivo by the gamma-secretase inhibitors BMS-289948 and BMS-299897.

S. Wagner, B. Lamb, D. Barten, 2005, Biochemical pharmacology.

Mechanisms of Cellular Uptake of Thrombin-Antithrombin II Complexes Role of the Low-Density Lipoprotein Receptor-Related Protein as a Serpin-Enzyme Complex Receptor.

D. Strickland, M. Kounnas, 1997, Trends in cardiovascular medicine.

D. Strickland, W. Argraves, M. Kounnas, 2022 .

Low Density Lipoprotein Receptor-related Protein/-Macroglobulin Receptor Mediates the Cellular Internalization and Degradation of Thrombospondin

I. Mikhailenko, D. Strickland, M. Kounnas, 1995, The Journal of Biological Chemistry.

Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor mediates cellular uptake of pro-urokinase.

J. Henkin, D. Strickland, W. Argraves, 1993, The Journal of biological chemistry.

Fibrinolysis protease receptors promote activation of astrocytes to express pro-inflammatory cytokines

S. L. Gonias, C. Marchese, M. Kounnas, 2019, Journal of Neuroinflammation.

An Overview of the Structure and Function of Glycoprotein 330, a Receptor Related to the α2‐Macroglobulin Receptor a

E. Loukinova, D. Strickland, S. Stefansson, 1994, Annals of the New York Academy of Sciences.

The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds and internalizes Pseudomonas exotoxin A.

D. Strickland, M. Thompson, R. Morris, 1992, The Journal of biological chemistry.

Pseudomonas exotoxin-mediated selection yields cells with altered expression of low-density lipoprotein receptor-related protein [published erratum appears in J Cell Biol 1995 Aug;130(4):1015]

S. Leppla, D. Strickland, J. Winkles, 1995, The Journal of cell biology.

gp330 on type II pneumocytes mediates endocytosis leading to degradation of pro-urokinase, plasminogen activator inhibitor-1 and urokinase-plasminogen activator inhibitor-1 complex.

J. Henkin, R. Mallampalli, D. Strickland, 1995, Journal of cell science.

Modulators of expression and function of LRP in Alzheimer's disease

B. Hyman, R. Tanzi, D. Strickland, 1997 .

D. Strickland, W. Argraves, Suzanne E. Williams, 1994 .

Identification of Glycoprotein 330 as an Endocytic Receptor for Apolipoprotein J/Clusterin (*)

B. Brewer, E. Loukinova, D. Strickland, 1995, The Journal of Biological Chemistry.

Role of the Ldl Receptor-Related Protein in Proteinase and Lipoprotein Catabolism

J. Lalouel, D. Strickland, W. Argraves, 1995 .

Selection of Pseudomonas Exotoxin—Resistant Cells with Altered Expression of α2MR/LRP

S. Leppla, D. Strickland, M. Kounnas, 1994 .

The Cellular Internalization and Degradation of Hepatic Lipase Is Mediated by Low Density Lipoprotein Receptor-related Protein and Requires Cell Surface Proteoglycans (*)

D. Strickland, H. Wong, W. Argraves, 1995, The Journal of Biological Chemistry.

Mutation Analysis of the Presenilin 1 N-terminal Domain Reveals a Broad Spectrum of γ-Secretase Activity toward Amyloid Precursor Protein and Other Substrates*

S. Wagner, Haipeng Cheng, M. Kounnas, 2010, The Journal of Biological Chemistry.

Apolipoprotein E receptor 2 deficiency decreases endothelial adhesion of monocytes and protects against autoimmune encephalomyelitis

C. Mineo, P. Shaul, J. Herz, 2021, Science Immunology.

Meprin-A and -B. Cell surface endopeptidases of the mouse kidney.

C. Gorbea, M. Kounnas, R. Wolz, 1991, The Journal of biological chemistry.

Glycoprotein 330, a member of the low density lipoprotein receptor family, binds lipoprotein lipase in vitro.

D. Strickland, W. Argraves, M. Kounnas, 1993, The Journal of biological chemistry.

Separation and differential activation of rat liver cytosolic cholesteryl ester hydrolase, triglyceride lipase and retinyl palmitate hydrolase by cholestyramine and protein kinases

Shobha Ghosh, W. Grogan, M. Kounnas, 1990, Lipids.

Dual roles of the transmembrane protein p23/TMP21 in the modulation of amyloid precursor protein metabolism

F. Wieland, L. Placanica, Haipeng Cheng, 2007, Molecular Neurodegeneration.

Immunological localization of glycoprotein 330, low density lipoprotein receptor related protein and 39 kDa receptor associated protein in embryonic mouse tissues.

D. Strickland, C. Haudenschild, W. Argraves, 1994, In vivo.

Reelin Depletion Protects Against Atherosclerosis by Decreasing Vascular Adhesion of Leukocytes

Richard G. Lee, C. Mineo, P. Shaul, 2021, Arteriosclerosis, thrombosis, and vascular biology.

The 39-kDa receptor-associated protein interacts with two members of the low density lipoprotein receptor family, alpha 2-macroglobulin receptor and glycoprotein 330.

D. Strickland, W. Argraves, M. Kounnas, 1992, The Journal of biological chemistry.

Cellular Internalization and Degradation of Antithrombin III-Thrombin, Heparin Cofactor II-Thrombin, and -Antitrypsin-Trypsin Complexes Is Mediated by the Low Density Lipoprotein Receptor-related Protein (*)

D. Strickland, F. Church, W. Argraves, 1996, The Journal of Biological Chemistry.

Interaction of single-chain urokinase with its receptor induces the appearance and disappearance of binding epitopes within the resultant complex for other cell surface proteins.

K. Preissner, J. Henkin, D. Cines, 1996, Blood.

NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease.

K. Herrup, S. Wagner, B. Lamb, 2009, The Journal of clinical investigation.

NGP 555, a γ-secretase modulator, lowers the amyloid biomarker, Aβ42, in cerebrospinal fluid while preventing Alzheimer's disease cognitive decline in rodents

J. Herz, M. Kounnas, D. W. Nowakowski, 2016, Alzheimer's & dementia.

Ubiquilin 1 Modulates Amyloid Precursor Protein Trafficking and Aβ Secretion*

Phillip B. Jones, B. Hyman, R. Tanzi, 2006, Journal of Biological Chemistry.

Ubiquilin 1 Modulates Amyloid Precursor Protein Trafficking

Phillip B. Jones, B. Hyman, R. Tanzi, 2006 .

Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway.

R. Katzman., C. Kawas, J. Troncoso, 2000, The Journal of clinical investigation.

Alzheimer Disease Aβ Production in the Absence of S-Palmitoylation-dependent Targeting of BACE1 to Lipid Rafts*

P. Wong, N. Seidah, M. Fukata, 2009, Journal of Biological Chemistry.

B. Hyman, R. Tanzi, A. Bush, 1995, Cell.

Reductions in β-amyloid concentrations in vivo by the γ-secretase inhibitors BMS-289948 and BMS-299897

S. Wagner, B. Lamb, D. Barten, 2005 .

Modulation of γ-Secretase Reduces β-Amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease

Xulun Zhang, Rudolph E. Tanzi, Sangram S. Sisodia, 2010, Neuron.

Fibrinolysis protease receptors promote activation of astrocytes to express pro-inflammatory cytokines

C. Marchese, M. Kounnas, E. Mantuano, 2019, Journal of Neuroinflammation.

Reelin depletion protects against autoimmune encephalomyelitis by decreasing vascular adhesion of leukocytes

C. Mineo, P. Shaul, J. Herz, 2020, Science Translational Medicine.

NGP 555, a γ-secretase modulator, shows a beneficial shift in the ratio of amyloid biomarkers in human cerebrospinal fluid at safe doses

J. Herz, M. Kounnas, Murat S. Durakoglugil, 2019, Alzheimer's & dementia.

Interaction of surfactant protein A with cellular myosin.

J. Wright, W. Argraves, M. Kounnas, 1994, American journal of respiratory cell and molecular biology.

Circulating Reelin promotes inflammation and modulates disease activity in acute and long COVID-19 cases

A. Nath, J. Herz, M. Kounnas, 2023, Frontiers in Immunology.

The α2‐Macroglobulin Receptor/Low Density Lipoprotein Receptor‐Related Protein and the Receptor‐Associated Protein

D. Strickland, W. Argraves, Suzanne E. Williams, 1994 .

S-Palmitoylation of γ-Secretase Subunits Nicastrin and APH-1*

P. Wong, T. Iwatsubo, Haipeng Cheng, 2009, Journal of Biological Chemistry.

D. Strickland, W. Argraves, M. Kounnas, 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

S-Palmitoylation of γ-Secretase Subunits Nicastrin and APH-1*

P. Wong, T. Iwatsubo, Haipeng Cheng, 2009, Journal of Biological Chemistry.

Safety of Anti-Reelin Therapeutic Approaches for Chronic Inflammatory Diseases

M. Kounnas, Murat S. Durakoglugil, L. Calvier, 2024, Cells.

Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor mediates the cellular internalization and degradation of thrombospondin. A process facilitated by cell-surface proteoglycans.

M. Kounnas, I. Mikhailenko, D. Strickland, 1995, The Journal of biological chemistry.