H. Rhim

发表

Regional metabolic alteration of Alzheimer's disease in mouse brain expressing mutant human APP-PS1 by 1H HR-MAS

Do-Wan Lee, Bo-Young Choe, Chi-Bong Choi, 2010, Behavioural Brain Research.

α-Synuclein has structural and functional similarities to small heat shock proteins

Chul-hak Yang, H. Rhim, S. Paik, 2004 .

Evidence that -synuclein functions as a negative regulator of Ca -dependent -granule release from human platelets

K. Chung, Jeon‐Han Park, S. Park, 2002 .

Evidence that alpha-synuclein functions as a negative regulator of Ca(++)-dependent alpha-granule release from human platelets.

K. Chung, Jeon‐Han Park, S. Park, 2002, Blood.

Development of a QA phantom and protocol for proton magnetic resonance spectroscopy

G. Jahng, O. Nalcioglu, C. Choi, 2009 .

Fine epitope mapping of monoclonal antibodies specific to human α-synuclein

E. Choi, H. Rhim, Hyo-Jin Park, 2006, Neuroscience Letters.

A novel link between the conformations, exposure of specific epitopes, and subcellular localization of α-synuclein.

Seongman Kang, Goo-Young Kim, H. Rhim, 2015, Biochimica et biophysica acta.

Celastrol ameliorates HIV-1 Tat-induced inflammatory responses via NF-kappaB and AP-1 inhibition and heme oxygenase-1 induction in astrocytes.

Soo‐Young Choi, Y. Bae, H. Rhim, 2014, Toxicology and applied pharmacology.

E 3 ubiquitin ligase RNF 2 interacts with the S 6 ′ proteasomal ATPase subunit and increases the ATP hydrolysis activity of S 6 ′

Seongman Kang, H. Rhim, Sun-Joo Lee, 2005 .

Temporal variability of glucocorticoid receptor activity is functionally important for the therapeutic action of fluoxetine in the hippocampus

D. M. Lyons, A. Schatzberg, I. Shim, 2014, Molecular Psychiatry.

Spatially restricted hypopigmentation associated with an Ednrbs-modifying locus on mouse chromosome 10.

W. Pavan, S. Tilghman, A. Aronzon, 2000, Genome research.

Matrix metalloproteinase-3 is activated by HtrA2/Omi in dopaminergic cells: Relevance to Parkinson’s disease

H. Rhim, Eun-mee Kim, Ji Ae Lee, 2012, Neurochemistry International.

Hip2 ubiquitin-conjugating enzyme has a role in UV-induced G1/S arrest and re-entry

Seongman Kang, H. Rhim, N. Hong, 2018, Genes & Genomics.

Activation of caspase-8 in 3-deazaadenosine-induced apoptosis of U-937 cells occurs downstream of caspase-3 and caspase-9 without Fas receptor-ligand interaction

Ho-Shik Kim, In-Kyung Kim, H. Rhim, 2001, Experimental & Molecular Medicine.

Cold atmospheric plasma (CAP), a novel physicochemical source, induces neural differentiation through cross-talk between the specific RONS cascade and Trk/Ras/ERK signaling pathway.

Seongman Kang, H. Rhim, Y. Hong, 2018, Biomaterials.

Apoptin Gene Delivery by the Functionalized Polyamidoamine Dendrimer Derivatives Induces Cell Death of U87-MG Glioblastoma Cells.

Jin Han, K. Ko, J. Choi, 2017, Journal of pharmaceutical sciences.

Expression of Human Immunodeficiency Virus Type 1 Tat Proteins in Escherichia coli and Application to Study Tat Functions

Soo‐Young Choi, Young‐Hee Kang, H. Rhim, 2000 .

HIV-1 Tat protein is able to efficiently transactivate the HIV-2 LTR through a TAR RNA element lacking both dinucleotide bulge binding sites.

A. Rice, H. Rhim, A. P. Rice, 1995, Virology.

Polyglutamine-expanded ataxin-1 recruits Cu/Zn-superoxide dismutase into the nucleus of HeLa cells.

Taesoo Kim, Seongman Kang, H. Rhim, 2003, Biochemical and biophysical research communications.

Effects of DBD-bio-plasma on the HSP70 of Fibroblasts: A New Approach on Change of Molecular Level by Heat Shock in the Cell

H. Rhim, E. Choi, Junyeong Yi, 2015 .

Harmless effects of argon plasma on caudal fin regeneration and embryogenesis of zebrafish: novel biological approaches for safe medical applications of bioplasma

Seongman Kang, Goo-Young Kim, H. Rhim, 2017, Experimental &Molecular Medicine.

Hip2 ubiquitin-conjugating enzyme overcomes radiation-induced G2/M arrest.

Song Hwa Jung, Seongman Kang, Goo-Young Kim, 2013, Biochimica et biophysica acta.

Alzheimer's disease-associated amyloid beta interacts with the human serine protease HtrA2/Omi

Seongman Kang, H. Rhim, Hyo-Jin Park, 2004, Neuroscience Letters.

The serine protease HtrA2/Omi cleaves Parkin and irreversibly inactivates its E3 ubiquitin ligase activity.

K. Chung, Seongman Kang, Goo-Young Kim, 2009, Biochemical and biophysical research communications.

Characterization of HtrA2-deficient Mouse Embryonic Fibroblast Cells Based on Morphology and Analysis of their Sensitivity in Response to Cell Death Stimuli.

Goo-Young Kim, H. Rhim, M. Nam, 2008 .

Essential roles of mitochondrial depolarization in neuron loss through microglial activation and attraction toward neurons

H. Rhim, Ji-Hye Han, M. Nam, 2013, Brain Research.

Serine Protease HtrA2/Omi Deficiency Impairs Mitochondrial Homeostasis and Promotes Hepatic Fibrogenesis via Activation of Hepatic Stellate Cells

W. Hur, S. Yoon, H. Rhim, 2019, Cells.

The homotrimeric structure of HtrA2 is indispensable for executing its serine protease activity

Seongman Kang, H. Rhim, Hyo-Jin Park, 2006, Experimental & Molecular Medicine.

Expression of Human SOD1 and Mutant SOD1 (G93A) in E. coli and Identification of SOD1 as a Substrate of HtrA2 Serine Protease

Goo-Young Kim, H. Rhim, Hyo-Jin Park, 2006 .

Stress-induced aggregation profiles of GST-alpha-synuclein fusion proteins: role of the C-terminal acidic tail of alpha-synuclein in protein thermosolubility and stability.

K. Chung, Jeon‐Han Park, S. Park, 2002, Biochemistry.

Purification of Human HtrA1 Expressed in E. coli and Characterization of Its Serine Protease Activity

Goo-Young Kim, H. Rhim, K. Kim, 2006 .

3-Deazaadenosine, a S-Adenosylhomocysteine Hydrolase Inhibitor, Has Dual Effects on NF-κB Regulation

Jeong-Hwa Lee, Ho-Shik Kim, Seong-Yun Jeong, 1999, The Journal of Biological Chemistry.

Hip2 interacts with cyclin B1 and promotes its degradation through the ubiquitin proteasome pathway

Seongman Kang, H. Rhim, D. Choi, 2010, FEBS letters.

Induction of apoptosis dependent on caspase activities and growth arrest in HL-60 cells by PGA2.

Ho-Shik Kim, In-Kyung Kim, H. Rhim, 2002, Prostaglandins & other lipid mediators.

Metabolic Alterations of the Zebrafish Brain after Acute Alcohol Treatment by 1 H Nuclear Magnetic Resonance Spectroscopy

C. Choi, B. Choe, Youl-Hun Seoung, 2013 .

Intracellular amyloid beta interacts with SOD1 and impairs the enzymatic activity of SOD1: implications for the pathogenesis of amyotrophic lateral sclerosis

Seongman Kang, Goo-Young Kim, H. Rhim, 2009, Experimental & Molecular Medicine.

Amyotrophic lateral sclerosis-related mutant superoxide dismutase 1 aggregates inhibit 14-3-3-mediated cell survival by sequestration into the JUNQ compartment

In Young Lee, E. Choi, Seongman Kang, 2017, Human molecular genetics.

Seongman Kang, H. Rhim, Ju-Hwang Park, 2020, International journal of molecular sciences.

Neurotrophic activity of DA-9801, a mixture extract of Dioscorea japonica Thunb. and Dioscorea nipponica Makino, in vitro.

H. Kuh, S. K. Yoon, Namho Kim, 2011, Journal of ethnopharmacology.

Autocatalytic Processing of HtrA2/Omi Is Essential for Induction of Caspase-dependent Cell Death through Antagonizing XIAP*

In-Kyung Kim, Sang‐Gun Ahn, Ki-Joong Kim, 2004, Journal of Biological Chemistry.

The serine protease HtrA2 cleaves UCH-L1 and inhibits its hydrolase activity: implication in the UCH-L1-mediated cell death.

H. Rhim, M. Nam, Dae-Wook Park, 2011, Biochemical and biophysical research communications.

Establishment of the expression system for studying the function of active caspase-3 in zebrafish

Goo-Young Kim, H. Rhim, Sangsoo Kim, 2009, Molecular Biology Reports.

E3 ligase activity of RING finger proteins that interact with Hip‐2, a human ubiquitin‐conjugating enzyme

Y. Sung, S. Kang, Seongman Kang, 2001, FEBS letters.

Synergistic interaction between tetra-arsenic oxide and paclitaxel in human cancer cells in vitro.

H. Kuh, B. Sung, H. Rhim, 2009, International journal of oncology.

Sox-4 is a positive regulator of Hep3B and HepG2 cells' apoptosis induced by prostaglandin (PG)A2 and Δ12-PGJ2

Jeong-Hwa Lee, Ho-Shik Kim, In-Kyung Kim, 2002, Experimental & Molecular Medicine.

Hip2 interacts with and destabilizes Smac/DIABLO.

Soo Young Lee, Seongman Kang, H. Rhim, 2010, Biochemical and biophysical research communications.

Functional identification of the pro-apoptotic effector domain in human Sox4.

W. Hur, S. Yoon, In-Kyung Kim, 2004, Biochemical and biophysical research communications.

HtrA2 regulates α-Synuclein-mediated mitochondrial reactive oxygen species production in the mitochondria of microglia.

Y. Sung, H. Rhim, S. Yoo, 2022, Biochemical and biophysical research communications.

The role of c-Myc and heat shock protein 70 in human hepatocarcinoma Hep3B cells during apoptosis induced by prostaglandin A2/Delta12-prostaglandin J2.

S. Jeong, H. Rhim, S. Ahn, 1998, Biochimica et biophysica acta.

Measurement and Assessment of Absolute Quantification from in Vitro Canine Brain Metabolites Using 500 MHz Proton Nuclear Magnetic Resonance Spectroscopy: Preliminary Results

C. Choi, B. Choe, H. Kim, 2008 .

α-Synuclein Interacts with Phospholipase D Isozymes and Inhibits Pervanadate-induced Phospholipase D Activation in Human Embryonic Kidney-293 Cells*

Y. Sung, T. Kwon, K. Chung, 2002, The Journal of Biological Chemistry.

Cytotoxic Effect of Urushiol on Human Ovarian Cancer Cells

H. Chun, H. Rhim, Ju-Youn Choi, 2001 .

Ex vivo detection for chronic ethanol consumption-induced neurochemical changes in rats

J. Han, C. Choi, B. Choe, 2012, Brain Research.

The JAK2 V617F mutation in de novo acute myelogenous leukemias

S. H. Lee, S. Nam, N. Yoo, 2006, Oncogene.

Minimal sequence requirements of a functional human immunodeficiency virus type 1 primer binding site

J. Wakefield, C. Morrow, H. Rhim, 1994, Journal of virology.

Deletions in the tRNA(Lys) primer-binding site of human immunodeficiency virus type 1 identify essential regions for reverse transcription

C. Morrow, H. Rhim, J. Park, 1991, Journal of virology.

Preferential killing of human lung cancer cell lines with mitochondrial dysfunction by nonthermal dielectric barrier discharge plasma

H. Rhim, K. Baik, E. Choi, 2013, Cell Death and Disease.

HtrA2/Omi deficiency causes damage and mutation of mitochondrial DNA.

Sungwook Han, Seongman Kang, H. Rhim, 2013, Biochimica et biophysica acta.

HtrA1 Is a Novel Antagonist Controlling Fibroblast Growth Factor (FGF) Signaling via Cleavage of FGF8

Cheol‐Hee Kim, Seongman Kang, Goo-Young Kim, 2012, Molecular and Cellular Biology.

SOX4 overexpression regulates the p53-mediated apoptosis in hepatocellular carcinoma: clinical implication and functional analysis in vitro.

H. Wang, W. Hur, J. Jang, 2010, Carcinogenesis.

Identification of cDNAs for Sox-4, an HMG-Box protein, and a novel human homolog of yeast splicing factor SSF-1 differentially regulated during apoptosis induced by prostaglandin A2/delta12-PGJ2 in Hep3B cells.

S. Jeong, H. Rhim, S Y Jeong, 1999, Biochemical and biophysical research communications.

Construction and characterization of a potent HIV-2 Tat transdominant mutant protein.

A. Rice, H. Rhim, C. H. Herrmann, 1994, Journal of acquired immune deficiency syndromes.

TAR RNA binding properties and relative transactivation activities of human immunodeficiency virus type 1 and 2 Tat proteins

A. Rice, H. Rhim, A. P. Rice, 1993, Journal of virology.

A new idea for simple and rapid monitoring of gene expression: requirement of nucleotide sequences encoding an N-terminal HA tag in the T7 promoter-driven expression in E. coli

Goo-Young Kim, H. Rhim, Jeong-Mi Moon, 2012, Biotechnology Letters.

RNAs Selected in vitro by the HIV-2 Tat Protein.

A. Rice, H. Rhim, A. P. Rice, 1997, Journal of biomedical science.

Quantitative biochemical characterization and biotechnological production of caspase modulator, XIAP: Therapeutic implications for apoptosis-associated diseases.

H. Rhim, M. Nam, Si-Eun Yun, 2018, Biochimica et biophysica acta. General subjects.

Hip2 ubiquitin-conjugating enzyme has a role in UV-induced G1/S arrest and re-entry

Seongman Kang, H. Rhim, N. Hong, 2018, Genes & Genomics.

HtrA2/Omi influences the stability of LON protease 1 and prohibitin, proteins involved in mitochondrial homeostasis.

Seongman Kang, H. Rhim, Hui-Gwan Goo, 2014, Experimental cell research.

HtrA2 suppresses autoimmune arthritis and regulates activation of STAT3

Hyeon-Beom Seo, Sung-Hwan Park, M. Cho, 2016, Scientific Reports.

A Simple and Accurate Genotype Analysis of the motor neuron degeneration 2 (mnd2) Mice: an Easy-to-Follow Guideline and Standard Protocol Applicable to Mutant Mouse Models.

Seongman Kang, Goo-Young Kim, H. Rhim, 2012 .

A Simple and Accurate Genotype Analysis of the motor neuron degeneration 2 (mnd2) Mice: an Easy-to-Follow Guideline and Standard Protocol Applicable to Mutant Mouse Model

Seongman Kang, Goo-Young Kim, H. Rhim, 2012 .

E3 ubiquitin ligase RNF2 interacts with the S6' proteasomal ATPase subunit and increases the ATP hydrolysis activity of S6'.

Seongman Kang, H. Rhim, Sun-Joo Lee, 2005, The Biochemical journal.

Wild-type and mutant HIV-1 and HIV-2 Tat proteins expressed in Escherichia coli as fusions with glutathione S-transferase.

A. Rice, H. Rhim, C. H. Herrmann, 1994, Journal of acquired immune deficiency syndromes.

NABi, a novel β-sheet breaker, inhibits Aβ aggregation and neuronal toxicity: Therapeutic implications for Alzheimer's disease.

Seongman Kang, H. Rhim, Ja-Young Jang, 2018, Biochimica et biophysica acta. General subjects.

ALS-linked mutant SOD1 proteins promote Aβ aggregates in ALS through direct interaction with Aβ.

Seongman Kang, H. Rhim, Ja-Young Jang, 2017, Biochemical and biophysical research communications.

N-terminal truncation circumvents proteolytic degradation of the human HtrA2/Omi serine protease in Escherichia coli: rapid purification of a proteolytically active HtrA2/Omi.

Seongman Kang, H. Rhim, Hyo-Jin Park, 2004, Protein expression and purification.

Pathogenic Role of Serine Protease HtrA2/Omi in Neurodegenerative Diseases.

Seongman Kang, H. Rhim, Hyangshuk Rhim, 2017, Current protein & peptide science.

β-Amyloid Precursor Protein Is a Direct Cleavage Target of HtrA2 Serine Protease

D. Min, Seongman Kang, H. Rhim, 2006, Journal of Biological Chemistry.

Beta-amyloid precursor protein is a direct cleavage target of HtrA2 serine protease. Implications for the physiological function of HtrA2 in the mitochondria.

D. Min, Seongman Kang, H. Rhim, 2006, The Journal of biological chemistry.

Characterization and Hsp104-induced artificial clearance of familial ALS-related SOD1 aggregates.

Seongman Kang, H. Rhim, Ja-Young Jang, 2013, Biochemical and biophysical research communications.

Oxidative stimuli affect polyglutamine aggregation and cell death in human mutant ataxin-1-expressing cells

Taesoo Kim, Seongman Kang, H. Rhim, 2003, Neuroscience Letters.

Effects of Argon-plasma Jet on the Cytoskeleton of Fibroblasts: Implications of a New Approach for Cancer Therapy

H. Rhim, Ji-Hye Han, E. Choi, 2012 .

Role of high-temperature requirement serine protease A 2 in rheumatoid inflammation

Wan-Uk Kim, Youngjae Park, H. Rhim, 2023, Arthritis Research & Therapy.

Delayed hair cycle in mnd2 mutant mice lacking HtrA2 serine protease activity.

H. Rhim, S. Yoo, M. Nam, 2022, Biochemical and biophysical research communications.

Intracellular Aβ and C99 aggregates induce mitochondria-dependent cell death in human neuroglioma H4 cells through recruitment of the 20S proteasome subunits

Seongman Kang, H. Rhim, Hyo-Jin Park, 2009, Brain Research.

Anti-complement effects of anion-substituted poly(vinyl alcohol) membranes

S. Hong, Y. Lee, H. Chun, 2004 .

Plasma protein adsorption to anion substituted poly(vinyl alcohol) membranes

S. Hong, Y. Lee, H. Chun, 2003 .

The Novel Human HtrA2 Ortholog in Zebrafish: New Molecular Insight and Challenges into the Imbalance of Homeostasis.

Goo-Young Kim, H. Rhim, M. Nam, 2022, Gene.

Rapid purification and analysis of α‐synuclein proteins: C‐terminal truncation promotes the conversion of α‐synuclein into a protease‐sensitive form in Escherichia coli

In-Kyung Kim, Seongman Kang, H. Rhim, 2002 .

PHB2 interacts with RNF2 and represses CP2c-stimulated transcription

C. Kim, Y. Ko, Seongman Kang, 2008, Molecular and Cellular Biochemistry.

A simple and rapid strategy for the molecular cloning and monitoring of mouse HtrA2 serine protease

Goo-Young Kim, H. Rhim, Sangsoo Kim, 2008, Biotechnology Letters.

Antigenicity of the region encoded by exon8 of the human serine protease, HtrA2/Omi, is associated with its protein solubility

Seongman Kang, H. Rhim, Hyo-Jin Park, 2003, Biotechnology Letters.

Establishment of the expression system of human HtrA2 in the zebrafish

Cheol‐Hee Kim, Sungpil Cho, Goo-Young Kim, 2006 .

alpha-Synuclein interacts with phospholipase D isozymes and inhibits pervanadate-induced phospholipase D activation in human embryonic kidney-293 cells.

Y. Sung, T. Kwon, K. Chung, 2002, The Journal of biological chemistry.

Development of a cone-shape phantom for multi-voxel MR spectroscopy

Bum-Soo Kim, Bo-Young Choe, G. Jahng, 2007, Journal of Neuroscience Methods.

Regional Absolute Quantification of the Neurochemical Profile of the Canine Brain: Investigation by Proton Nuclear Magnetic Resonance Spectroscopy and Tissue Extraction

C. Choi, B. Choe, D. Woo, 2010 .

The sCMV IE enhancer/promoter system for high-level expression and efficient functional studies of target genes in mammalian cells and zebrafish

Goo-Young Kim, H. Rhim, Ji-Hye Han, 2011, Biotechnology Letters.

A new idea for simple and rapid monitoring of gene expression: requirement of nucleotide sequences encoding an N-terminal HA tag in the T7 promoter-driven expression in E. coli

Goo-Young Kim, H. Rhim, Jeong-mi Moon, 2012, Biotechnology Letters.

Exon2 of HIV-2 Tat contributes to transactivation of the HIV-2 LTR by increasing binding affinity to HIV-2 TAR RNA.

H. Rhim, A. P. Rice, 1994, Nucleic acids research.

Functional significance of the dinucleotide bulge in stem-loop1 and stem-loop2 of HIV-2 TAR RNA.

H. Rhim, A. P. Rice, 1994, Virology.

Cold atmospheric plasma (CAP), a novel physicochemical source, induces neural differentiation through cross-talk between the specific RONS cascade and Trk/Ras/ERK signaling pathway.

Seongman Kang, H. Rhim, Y. Hong, 2018, Biomaterials.

Alpha-synuclein has structural and functional similarities to small heat shock proteins.

Chul-hak Yang, H. Rhim, S. Paik, 2004, Biochemical and biophysical research communications.

The serine protease HtrA2 cleaves UCH-L1 and inhibits its hydrolase activity: implication in the UCH-L1-mediated cell death.

H. Rhim, Dae-Wook Park, Min-Kyung Nam, 2011, Biochemical and biophysical research communications.

Ex vivo detection for chronic ethanol consumption-induced neurochemical changes in rats

J. Han, C. Choi, B. Choe, 2012, Brain Research.

Improved recovery of active GST-fusion proteins from insoluble aggregates: solubilization and purification conditions using PKM2 and HtrA2 as model proteins.

Goo-Young Kim, H. Rhim, Sangsoo Kim, 2011, BMB reports.

Prostaglandin A2 induces caspase-independent apoptosis in hepatocellular carcinoma cells.

Ho-Shik Kim, In-Kyung Kim, H. Rhim, 2005, The Korean journal of hepatology.