H. Wakizaka

发表

Imaging of I2-imidazoline receptors by small-animal PET using 2-(3-fluoro-[4-11C]tolyl)-4,5-dihydro-1H-imidazole ([11C]FTIMD).

Ming-Rong Zhang, Y. Kimura, Tomoteru Yamasaki, 2010, Nuclear medicine and biology.

Evaluation of Limiting Brain Penetration Related to P-glycoprotein and Breast Cancer Resistance Protein Using [11C]GF120918 by PET in Mice

Ming-Rong Zhang, Y. Kimura, Tomoteru Yamasaki, 2011, Molecular Imaging and Biology.

Radiosynthesis and evaluation of [11C]YM-202074 as a PET ligand for imaging the metabotropic glutamate receptor type 1.

Ming-Rong Zhang, Tomoteru Yamasaki, Joji Yui, 2010, Nuclear medicine and biology.

Improved Visualization and Specific Binding for Metabotropic Glutamate Receptor Subtype 1 (mGluR1) Using [11C]ITMM with Ultra-High Specific Activity in Small-Animal PET

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2015, PloS one.

Synthesis of [11C]carbonyl-labeled cyclohexyl (5-(2-acetamidobenzo[d]thiazol-6-yl)-2-methylpyridin-3-yl)carbamate ([11C-carbonyl]PK68) as a potential PET tracer for receptor-interacting protein 1 kinase

Ming-Rong Zhang, Tomoteru Yamasaki, K. Kumata, 2022, EJNMMI Radiopharmacy and Chemistry.

Identification and Development of a New Positron Emission Tomography Ligand 4-(2-Fluoro-4-[11C]methoxyphenyl)-5-((1-methyl-1H-pyrazol-3-yl)methoxy)picolinamide for Imaging Metabotropic Glutamate Receptor Subtype 2 (mGlu2).

Steven H. Liang, Ming-Rong Zhang, D. Sheffler, 2020, Journal of medicinal chemistry.

In Vivo Measurement of the Affinity and Density of Metabotropic Glutamate Receptor Subtype 1 in Rat Brain Using 18F-FITM in Small-Animal PET

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2012, The Journal of Nuclear Medicine.

Synthesis and in vivo evaluation of ¹⁸F-fluoroethyl GF120918 and XR9576 as positron emission tomography probes for assessing the function of drug efflux transporters.

Ming-Rong Zhang, Tomoteru Yamasaki, Joji Yui, 2011, Bioorganic & medicinal chemistry.

Binding potential of (E)-[¹¹C]ABP688 to metabotropic glutamate receptor subtype 5 is decreased by the inclusion of its ¹¹C-labelled Z-isomer.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2014, Nuclear medicine and biology.

Biological washout modelling for in-beam PET: rabbit brain irradiation by 11C and 15O ion beams

I. Kanno, C. Seki, T. Yamaya, 2020, Physics in medicine and biology.

Immuno-OpenPET: a novel approach for early diagnosis and image-guided surgery for small resectable pancreatic cancer

Atsushi B. Tsuji, G. Akamatsu, Ming-Rong Zhang, 2020, Scientific Reports.

Synthesis, metabolite analysis, and in vivo evaluation of [(11)C]irinotecan as a novel positron emission tomography (PET) probe.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2013, Nuclear medicine and biology.

Integrated treatment using intraperitoneal radioimmunotherapy and positron emission tomography-guided surgery with 64Cu-labeled cetuximab to treat early- and late-phase peritoneal dissemination in human gastrointestinal cancer xenografts

Atsushi B. Tsuji, Ming-Rong Zhang, T. Higashi, 2018, Oncotarget.

Development of a Whole-Body Dual Ring OpenPET for in-Beam PET

Tetsuya Shinaji, Hideaki Tashima, Eiji Yoshida, 2014, IEEE Transactions on Radiation and Plasma Medical Sciences.

3D Compton image reconstruction method for whole gamma imaging

Atsushi B. Tsuji, K. Parodi, K. Kamada, 2020, Physics in Medicine and Biology.

OAT3-Mediated Extrusion of the 99mTc-ECD Metabolite in the Mouse Brain

Atsushi B. Tsuji, Ming-Rong Zhang, Joji Yui, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Synthesis and evaluation of [11C]XR9576 to assess the function of drug efflux transporters using PET

Ming-Rong Zhang, Tomoteru Yamasaki, Joji Yui, 2010, Annals of nuclear medicine.

High-throughput screening with nanoimprinting 3D culture for efficient drug development by mimicking the tumor environment.

Ming-Rong Zhang, Y. Fujibayashi, A. Waki, 2015, Biomaterials.

Performance evaluation of a whole-body prototype PET scanner with four-layer DOI detectors

G. Akamatsu, T. Yamaya, F. Nishikido, 2019, Physics in medicine and biology.

Development of a small prototype for a proof-of-concept of OpenPET imaging

Daisuke Kokuryo, Hideaki Tashima, Eiji Yoshida, 2011, Physics in medicine and biology.

6-[124I]Iodo-9-pentylpurine for imaging the activity of the sodium iodide symporter in the brain.

Atsushi B. Tsuji, Ming-Rong Zhang, H. Ishii, 2020, Journal of medicinal chemistry.

In Vivo Simultaneous Imaging of Vascular Pool and Hypoxia with a HT-29 Tumor Model: the Application of Dual-Isotope SPECT/PET/CT

Atsushi B. Tsuji, Y. Fujibayashi, T. Saga, 2015 .

New brain phantoms suitable for brain scanners with hemisphere detector arrangement

G. Akamatsu, T. Yamaya, E. Yoshida, 2017, 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC).

Imaging of activity of multidrug resistance-associated protein 1 in the lungs.

Ming-Rong Zhang, H. Wakizaka, Maki Okada, 2013, American journal of respiratory cell and molecular biology.

Radiosynthesis and in vivo evaluation of 11C-labeled BMS-193885 and its desmethyl analog as PET tracers for neuropeptide Y1 receptors

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2019, EJNMMI Radiopharmacy and Chemistry.

A 11C-Labeled 1,4-Dihydroquinoline Derivative as a Potential PET Tracer for Imaging of Redox Status in Mouse Brain

Ming-Rong Zhang, H. Wakizaka, Maki Okada, 2015, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Design, Synthesis, and Evaluation of 11C-Labeled 3-Acetyl-Indole Derivatives as a Novel Positron Emission Tomography Imaging Agent for Diacylglycerol Kinase Gamma (DGKγ) in Brain.

Ming-Rong Zhang, T. Ohashi, Tomoteru Yamasaki, 2021, Journal of medicinal chemistry.

A useful PET probe [11C]BU99008 with ultra-high specific radioactivity for small animal PET imaging of I2-imidazoline receptors in the hypothalamus.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2017, Nuclear medicine and biology.

Efficient synthesis and chiral separation of 11C-labeled ibuprofen assisted by DMSO for imaging of in vivo behavior of the individual isomers by positron emission tomography.

Ming-Rong Zhang, Kenji Furutsuka, N. Nengaki, 2011, Bioorganic & medicinal chemistry.

Development of the Fibronectin-Mimetic Peptide KSSPHSRN(SG)5RGDSP as a Novel Radioprobe for Molecular Imaging of the Cancer Biomarker α5β1 Integrin.

Ming-Rong Zhang, Y. Fujibayashi, T. Saga, 2015, Biological & pharmaceutical bulletin.

Radiosynthesis and evaluation of new PET ligands for peripheral cannabinoid receptor type 1 imaging.

Ming-Rong Zhang, Tomoteru Yamasaki, Masayuki Fujinaga, 2017, Bioorganic & medicinal chemistry letters.

In vivo evaluation of limiting brain penetration of probes for α(2C)-adrenoceptor using small-animal positron emission tomography.

Ming-Rong Zhang, Tomoteru Yamasaki, Joji Yui, 2010, ACS chemical neuroscience.

Radiotheranostic Agent 64Cu-cyclam-RAFT-c(-RGDfK-)4 for Management of Peritoneal Metastasis in Ovarian Cancer

Atsushi B. Tsuji, Ming-Rong Zhang, T. Higashi, 2020, Clinical Cancer Research.

PET imaging and biodistribution analysis of the effects of succinylated gelatin combined with L-lysine on renal uptake and retention of ⁶⁴Cu-cyclam-RAFT-c(-RGDfK-)₄ in vivo.

Ming-Rong Zhang, Y. Fujibayashi, T. Saga, 2014, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Developing new PET tracers to image the growth hormone secretagogue receptor 1a (GHS-R1a).

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2017, Nuclear medicine and biology.

Identification and Development of A New Positron Emission Tomography Ligand 4-(2-Fluoro-4-[ 11 C]methoxyphenyl)-5-((1-methyl-1 H -pyrazol-3-yl)methoxy)picolinamide for Imaging Metabotropic Glutamate Receptor Subtype 2 (mGlu 2 )

Steven H. Liang, Ming-Rong Zhang, D. Sheffler, 2021 .

Novel system using microliter order sample volume for measuring arterial radioactivity concentrations in whole blood and plasma for mouse PET dynamic study

I. Kanno, Y. Kimura, K. Hatano, 2013, Physics in medicine and biology.

Change in the Binding of [11C]BU99008 to Imidazoline I2 Receptor Using Brain PET in Zucker Rats

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2019, Molecular Imaging and Biology.

In vivo evaluation of a new ¹⁸F-labeled PET ligand, [¹⁸F]FEBU, for the imaging of I₂-imidazoline receptors.

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2015, Nuclear medicine and biology.

Synthesis and evaluation of PET probes for the imaging of I2 imidazoline receptors in peripheral tissues.

Ming-Rong Zhang, Tomoteru Yamasaki, Joji Yui, 2012, Nuclear medicine and biology.

imaging of I 2 -imidazoline receptors

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2015 .

Development of an In Vivo Method to Estimate Effective Drug Doses and Quantify Fatty Acid Amide Hydrolase in Rodent Brain using Positron Emission Tomography Tracer [11C]DFMC

Ming-Rong Zhang, Tomoteru Yamasaki, Masayuki Fujinaga, 2020, The Journal of Pharmacology and Experimental Therapeutics.

C-type natriuretic peptide specifically acts on the pylorus and large intestine in mouse gastrointestinal tract.

Atsushi B. Tsuji, T. Saga, H. Wakizaka, 2013, The American journal of pathology.

PET study using [11C]FTIMD with ultra-high specific activity to evaluate I2-imidazoline receptors binding in rat brains.

Ming-Rong Zhang, Y. Kimura, Tomoteru Yamasaki, 2012, Nuclear medicine and biology.

Performance evaluation of VRAIN: a brain-dedicated PET with a hemispherical detector arrangement

G. Akamatsu, T. Yamaya, E. Yoshida, 2022, Physics in medicine and biology.

Kinetics and metabolism of apocynin in the mouse brain assessed with positron-emission tomography.

Ming-Rong Zhang, H. Wakizaka, Maki Okada, 2018, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Visualization of Acute Liver Damage Induced by Cycloheximide in Rats Using PET with [18F]FEDAC, a Radiotracer for Translocator Protein (18 kDa)

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2014, PloS one.

11C-Labeled Radiotracer for Noninvasive and Quantitative Assessment of the Thiocyanate Efflux System in the Brain.

Ming-Rong Zhang, Satoshi Tsukamoto, N. Nengaki, 2022, Bioconjugate chemistry.

Micro–Positron Emission Tomography/Contrast-Enhanced Computed Tomography Imaging of Orthotopic Pancreatic Tumor–Bearing Mice Using the αvβ3 Integrin Tracer 64Cu-Labeled Cyclam-RAFT-c(-RGDfK-)4

Atsushi B. Tsuji, Y. Fujibayashi, T. Saga, 2013, Molecular imaging.

Molecular imaging of ectopic metabotropic glutamate 1 receptor in melanoma with a positron emission tomography radioprobe 18F‐FITM

Ming-Rong Zhang, Lin Xie, Tomoteru Yamasaki, 2014, International journal of cancer.

Evaluation of the P-glycoprotein- and breast cancer resistance protein-mediated brain penetration of 11C-labeled topotecan using small-animal positron emission tomography.

Ming-Rong Zhang, Tomoteru Yamasaki, Joji Yui, 2011, Nuclear medicine and biology.

Controlled Administration of Penicillamine Reduces Radiation Exposure in Critical Organs during 64Cu-ATSM Internal Radiotherapy: A Novel Strategy for Liver Protection

Ming-Rong Zhang, Y. Fujibayashi, T. Saga, 2014, PloS one.

Long-term effects of cerebral hypoperfusion on neural density and function using misery perfusion animal model

I. Kanno, K. Masamoto, Hiroshi Ito, 2016, Scientific Reports.

Development of 1-N-11C-Methyl-l- and -d-Tryptophan for pharmacokinetic imaging of the immune checkpoint inhibitor 1-Methyl-Tryptophan

Ming-Rong Zhang, T. Suhara, J. Maeda, 2015, Scientific Reports.

Off-tumor IDO1 target engagements determine the cancer-immune set point and predict the immunotherapeutic efficacy

Ming-Rong Zhang, Yihai Cao, T. Shimokawa, 2021, Journal for ImmunoTherapy of Cancer.

Upregulation of Striatal Metabotropic Glutamate Receptor Subtype 1 (mGluR1) in Rats with Excessive Glutamate Release Induced by N-Acetylcysteine

Ming-Rong Zhang, Tomoteru Yamasaki, Masayuki Fujinaga, 2022, Neurotoxicity Research.

Dynamic Changes in Striatal mGluR1 But Not mGluR5 during Pathological Progression of Parkinson's Disease in Human Alpha-Synuclein A53T Transgenic Rats: A Multi-PET Imaging Study

Lin Xie, Satoshi Shiomi, Hidekatsu Wakizaka, 2016, The Journal of Neuroscience.

Development of an In Vivo Method to Estimate Effective Drug Doses and Quantify Fatty Acid Amide Hydrolase in Rodent Brain using Positron Emission Tomography Tracer [11C]DFMC

Ming-Rong Zhang, Tomoteru Yamasaki, Masayuki Fujinaga, 2020, The Journal of Pharmacology and Experimental Therapeutics.

Fatty Acid Synthase Is a Key Target in Multiple Essential Tumor Functions of Prostate Cancer: Uptake of Radiolabeled Acetate as a Predictor of the Targeted Therapy Outcome

Atsushi B. Tsuji, Y. Fujibayashi, Jason S. Lewis, 2013, PloS one.

Regorafenib as a potential adjuvant chemotherapy agent in disseminated small colon cancer: Drug selection outcome of a novel screening system using nanoimprinting 3-dimensional culture with HCT116-RFP cells.

Y. Fujibayashi, T. Saga, H. Wakizaka, 2016, International journal of oncology.

Regorafenib as a potential adjuvant chemotherapy

Y. Fujibayashi, T. Saga, H. Wakizaka, 2016 .

Comparison of 2-amino-[3-11C]isobutyric acid and 2-deoxy-2-[18F]fluoro-D-glucose in nude mice with xenografted tumors and acute inflammation

T. Saga, H. Wakizaka, A. Tsuji, 2012, Nuclear medicine communications.

Development of a single-ring OpenPET prototype

Hideaki Tashima, Eiji Yoshida, Taiga Yamaya, 2013 .

Small-animal PET study for noninvasive quantification of transmembrane AMPA receptor regulatory protein γ-8 (TARP γ-8) in the brain

Steven H. Liang, Tomoteru Yamasaki, K. Kumata, 2023, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Noninvasive Quantification of Metabotropic Glutamate Receptor Type 1 with [11C]ITDM: a Small-Animal PET Study

Lin Xie, Hidekatsu Wakizaka, Kazunori Kawamura, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Washout rate in rat brain irradiated by a 11C beam after acetazolamide loading using a small single-ring OpenPET prototype

Eiji Yoshida, Taiga Yamaya, Fumihiko Nishikido, 2016, Physics in medicine and biology.

Translocator protein (18 kDa), a potential molecular imaging biomarker for non-invasively distinguishing non-alcoholic fatty liver disease.

Lin Xie, Tomoteru Yamasaki, Joji Yui, 2012, Journal of hepatology.

In vivo imaging and quantitative analysis of TSPO in rat peripheral tissues using small-animal PET with [18F]FEDAC.

O. Inoue, Tomoteru Yamasaki, Joji Yui, 2010, Nuclear medicine and biology.

Development of a simultaneous optical/PET imaging system for awake mice

Y. Ikoma, T. Yamaya, E. Yoshida, 2016, Physics in medicine and biology.

First prototyping of a dedicated PET system with the hemisphere detector arrangement

Hideaki Tashima, Eiji Yoshida, Taiga Yamaya, 2019, Physics in medicine and biology.

Development of 2-(2-(3-(4-([18F]Fluoromethoxy- d2)phenyl)-7-methyl-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)-4-isopropoxyisoindoline-1,3-dione for Positron-Emission-Tomography Imaging of Phosphodiesterase 10A in the Brain.

Lin Xie, Tomoteru Yamasaki, K. Kumata, 2018, Journal of medicinal chemistry.

Usefulness of PET-guided surgery with 64Cu-labeled cetuximab for resection of intrapancreatic residual tumors in a xenograft mouse model of resectable pancreatic cancer

G. Akamatsu, T. Higashi, M. Yoshimoto, 2021, Nuclear medicine communications.

Upregulation of Striatal Metabotropic Glutamate Receptor Subtype 1 (mGluR1) in Rats with Excessive Glutamate Release Induced by N-Acetylcysteine

Tomoteru Yamasaki, Masayuki Fujinaga, Yiding Zhang, 2022, Neurotoxicity research.

Development of a small single-ring OpenPET prototype with a novel transformable architecture

Tetsuya Shinaji, Hideaki Tashima, Eiji Yoshida, 2016, Physics in medicine and biology.

Utility of Translocator Protein (18 kDa) as a Molecular Imaging Biomarker to Monitor the Progression of Liver Fibrosis

Lin Xie, Tomoteru Yamasaki, Joji Yui, 2015, Scientific Reports.

In-vivo imaging of blood–brain barrier permeability using positron emission tomography with 2-amino-[3-11C]isobutyric acid

Atsushi B. Tsuji, I. Aoki, Y. Ikoma, 2015, Nuclear medicine communications.

Preclinical assessment of early tumor response after irradiation by positron emission tomography with 2-amino-[3-¹¹C]isobutyric acid.

Atsushi B. Tsuji, T. Saga, H. Wakizaka, 2015, Oncology reports.

Immuno-OpenPET: a novel approach for early diagnosis and image-guided surgery for small resectable pancreatic cancer

G. Akamatsu, T. Higashi, M. Yoshimoto, 2020, Scientific Reports.

Measurement of biological washout rates depending on tumor vascular status in 15O in-beam rat-PET

I. Kanno, Nobuhiro Nitta, C. Seki, 2022, Physics in medicine and biology.

Neuroprotective effects of minocycline and KML29, a potent inhibitor of monoacylglycerol lipase, in an experimental stroke model: a small-animal positron emission tomography study

Steven H. Liang, Tomoteru Yamasaki, A. Hatori, 2021, Theranostics.

First demonstration of in vivo mapping for regional brain monoacylglycerol lipase using PET with [11C]SAR127303

Lu Wang, Tomoyuki Ohya, Steven H. Liang, 2018, NeuroImage.

Development of sealed 22Na phantoms for PET system QA/QC: uniformity and stability evaluation

G. Akamatsu, T. Yamaya, E. Yoshida, 2019, Nuclear Science Symposium and Medical Imaging Conference.

Modified NEMA NU-2 performance evaluation methods for a brain-dedicated PET system with a hemispherical detector arrangement

Hideaki Tashima, Taiga Yamaya, Hidekatsu Wakizaka, 2019, Biomedical physics & engineering express.

Benzyl [(11)C]Hippurate as an Agent for Measuring the Activities of Organic Anion Transporter 3 in the Brain and Multidrug Resistance-Associated Protein 4 in the Heart of Mice.

A. Gee, Joji Yui, T. Fukumura, 2016, Journal of medicinal chemistry.

Improvement of brain uptake for in vivo PET imaging of astrocytic oxidative metabolism using benzyl [1-(11)C]acetate.

O. Inoue, R. Nakao, H. Wakizaka, 2013, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Development of the helmet-chin PET prototype

Hideaki Tashima, Eiji Yoshida, Taiga Yamaya, 2015, 2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC).

[11C]Raclopride binding in the striatum of minimally restrained and free‐walking awake mice in a positron emission tomography study

I. Kanno, Hiroshi Ito, J. Maeda, 2015, Synapse.

Mechanisms of glutathione-conjugate efflux from the brain into blood: Involvement of multiple transporters in the course

H. Wakizaka, Maki Okada, T. Okamura, 2018, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Submillimeter-Resolution PET for High-Sensitivity Mouse Brain Imaging

T. Yamaya, F. Nishikido, H. Tashima, 2022, The Journal of Nuclear Medicine.

Positron annihilation spectroscopy of biological tissue in 11C irradiation

Eiji Yoshida, Taiga Yamaya, Fumihiko Nishikido, 2014, Physics in medicine and biology.

Tumour status prediction by means of carbon-ion beam irradiation: comparison of washout rates between in-beam PET and DCE-MRI in rats

I. Kanno, Y. Ikoma, Nobuhiro Nitta, 2023, Physics in medicine and biology.

Molecular imaging of ectopic metabotropic glutamate 1 receptor in melanoma with a positron emission tomography radioprobe 18F‐FITM

Lin Xie, Tomoteru Yamasaki, Joji Yui, 2014, International journal of cancer.

In Vivo Monitoring for Regional Changes of Metabotropic Glutamate Receptor Subtype 1 (mGluR1) in Pilocarpine-Induced Epileptic Rat Brain by Small-Animal PET

Lin Xie, Tomoteru Yamasaki, A. Hatori, 2017, Scientific Reports.