W. Trigg

发表

[¹⁸F]GE-180: a novel fluorine-18 labelled PET tracer for imaging Translocator protein 18 kDa (TSPO).

M. Thaning, H. Wadsworth, P. Jones, 2012, Bioorganic & medicinal chemistry letters.

In Vivo Detection of Age- and Disease-Related Increases in Neuroinflammation by 18F-GE180 TSPO MicroPET Imaging in Wild-Type and Alzheimer's Transgenic Mice

B. Liu, Mi-Ae Park, C. Lemere, 2015, The Journal of Neuroscience.

Flutriciclamide (18F-GE180) PET: First-in-Human PET Study of Novel Third-Generation In Vivo Marker of Human Translocator Protein

A. Waldman, D. Brooks, R. Hinz, 2016, The Journal of Nuclear Medicine.

[18F]GE-180 PET Detects Reduced Microglia Activation After LM11A-31 Therapy in a Mouse Model of Alzheimer's Disease

S. Gambhir, Thuy-vi Nguyen, M. James, 2017, Theranostics.

Exploration of the structure-activity relationship of the diaryl anilide class of ligands for translocator protein--potential novel positron emitting tomography imaging agents.

H. Wadsworth, P. Jones, Wai-Fung Chau, 2012, Bioorganic & medicinal chemistry letters.

Dynamic TSPO-PET for assessing early effects of cerebral hypoxia and resuscitation in new born pigs.

E. Malinen, O. Saugstad, W. Trigg, 2018, Nuclear medicine and biology.

Space-like 56Fe irradiation manifests mild, early sex-specific behavioral and neuropathological changes in wildtype and Alzheimer’s-like transgenic mice

Mi-Ae Park, C. Lemere, M. D. Di Carli, 2019, Scientific Reports.

Flutriciclamide ( 18 F-GE 180 ) PET

A. Waldman, D. Brooks, C. Buckley, 2016 .

Flutriciclamide ( 18 F-GE 180 ) PET : first in human PET study of novel 3 rd generation in vivo marker of human translator protein . Running title : 18 F-GE 180 PET

A. Waldman, D. Brooks, R. Hinz, 2016 .

Flutriciclamide (18F-GE180) PET

A. Waldman, D. Brooks, C. Buckley, 2016 .

Explorer Flutriciclamide ( 18 F-GE 180 ) PET

A. Waldman, D. Brooks, R. Hinz, 2016 .

Simplifying [18F]GE-179 PET: are both arterial blood sampling and 90-min acquisitions essential?

D. Brooks, J. Duncan, A. Hammers, 2018, EJNMMI Research.

Radiosynthesis of (R,S)‐[18F]GE387: A Potential PET Radiotracer for Imaging Translocator Protein 18 kDa (TSPO) with Low Binding Sensitivity to the Human Gene Polymorphism rs6971

David P. Williamson, M. Kassiou, F. Aigbirhio, 2019, ChemMedChem.

18F-GE-180: a novel TSPO radiotracer compared to 11C-R-PK11195 in a preclinical model of stroke

R. Maroy, H. Boutin, A. Gerhard, 2015, European Journal of Nuclear Medicine and Molecular Imaging.

Initial evaluation of [18F]GE-180 PET imaging in relapsing-remitting multiple sclerosis patients.

D. Brooks, R. Hinz, C. Buckley, 2015 .

Development of an automated, GMP compliant FASTlabTM radiosynthesis of [18 F]GE-179 for the clinical study of activated NMDA receptors.

I. Khan, Andrew Black, W. Trigg, 2020, Journal of labelled compounds & radiopharmaceuticals.

Comment on " In Vivo [18F]GE-179 Brain Signal Does Not Show NMDA-Specific Modulation with Drug Challenges in Rodents and Nonhuman Primates".

O. Howes, D. Brooks, J. Duncan, 2018, ACS chemical neuroscience.

The development of potential new fluorine-18 labelled radiotracers for imaging the GABA(A) receptor.

P. Jones, D. O'Shea, A. Ewan, 2013, Bioorganic & Medicinal Chemistry Letters.

Positron Emission Tomography Imaging of Macrophages in Atherosclerosis with 18F-GE-180, a Radiotracer for Translocator Protein (TSPO)

J. Knuuti, S. Ylä-Herttuala, A. Saraste, 2018, Contrast media & molecular imaging.

Comparative Evaluation of Three TSPO PET Radiotracers in a LPS-Induced Model of Mild Neuroinflammation in Rats

R. Hinz, M. Kassiou, T. Reekie, 2016, Molecular Imaging and Biology.

Exploration of the impact of stereochemistry on the identification of the novel translocator protein PET imaging agent [(18)F]GE-180.

P. Jones, Wai-Fung Chau, Clare Durrant, 2015, Nuclear medicine and biology.

An improved, regioselective synthesis of the radiolabelling precursor for the translocator protein targeting positron emission tomography imaging radiotracer [18F]GE-180

M. Thaning, H. Wadsworth, J. Passmore, 2014 .

The development of an automated and GMP compliant FASTlab™ Synthesis of [(18) F]GE-180; a radiotracer for imaging translocator protein (TSPO).

E. Horn, D. Mantzilas, I. Gausemel, 2014, Journal of labelled compounds & radiopharmaceuticals.

Exploration of the structure-activity relationship of a novel tetracyclic class of TSPO ligands-potential novel positron emitting tomography imaging agents.

S. Luthra, E. Årstad, H. Wadsworth, 2013, Bioorganic & medicinal chemistry letters.

Initial Evaluation of 18 F-GE-179 , A Putative PET Tracer for Activated N-Methyl D-Aspartate Receptors

Alexander Hammers, David J. Brooks, John S. Duncan, 2014 .

NMDA receptor binding in focal epilepsies

M. Symms, D. Brooks, S. Luthra, 2015, Journal of Neurology, Neurosurgery & Psychiatry.

Synthesis of C5-substituted AE-bicyclic analogues of lycoctonine, inuline and methyllycaconitine

B. Potter, I. S. Blagbrough, W. Trigg, 1998 .

Evaluation of a novel series of fluorine-18-labeled imidazobenzodiazepines as potential new positron emission tomography radioligands for the GABAA receptor.

P. Jones, Wai-Fung Chau, D. O'Shea, 2014, Nuclear medicine and biology.

Copper‐mediated reduction of 2‐[18F]fluoroethyl azide to 2‐[18F]fluoroethylamine

M. Glaser, E. Årstad, W. Trigg, 2012 .

Use of 2-[(18)F]fluoroethylazide for the Staudinger ligation - Preparation and characterisation of GABA(A) receptor binding 4-quinolones.

S. Luthra, M. Glaser, P. Jones, 2010, Bioorganic & medicinal chemistry letters.

Detection of Microglial Activation in an Acute Model of Neuroinflammation Using PET and Radiotracers 11C-(R)-PK11195 and 18F-GE-180

J. Rinne, J. Johansson, L. Airas, 2014, The Journal of Nuclear Medicine.

Synthesis of novel unsaturated AE-bicyclic analogues of lycoctonine, inuline and methyllycaconitine: With olefinic J = 13.5 Hz, but still cis

B. Potter, I. S. Blagbrough, W. Trigg, 1998 .

Initial Evaluation of 18F-GE-179, a Putative PET Tracer for Activated N-Methyl d-Aspartate Receptors

Alexander Hammers, Caroline Micallef, John S Duncan, 2014, The Journal of Nuclear Medicine.

(99m)Tc SPECT imaging agent based on cFLFLFK for the detection of FPR1 in inflammation.

S. Luthra, W. Trigg, N. Long, 2015, Dalton transactions.

99 m Tc SPECT imaging agent based on cFLFLFK for the detection of FPR 1 in inflammation

W. Trigg, N. Long, F. Gavins, 2015 .

In vivo PET imaging of the neuroinflammatory response in rat spinal cord injury using the TSPO tracer [18F]GE-180 and effect of docosahexaenoic acid

J. Tremoleda, J. Sosabowski, J. Foster, 2016, European Journal of Nuclear Medicine and Molecular Imaging.

In Vivo PET Imaging Demonstrates Diminished Microglial Activation After Fingolimod Treatment in an Animal Model of Multiple Sclerosis

J. Rinne, J. Johansson, L. Airas, 2015, The Journal of Nuclear Medicine.

Long-Term Sex- and Genotype-Specific Effects of 56Fe Irradiation on Wild-Type and APPswe/PS1dE9 Transgenic Mice

Mi-Ae Park, C. Lemere, M. D. Di Carli, 2021, International journal of molecular sciences.

Kinetic analysis of the translocator protein positron emission tomography ligand [18F]GE-180 in the human brain

D. Sharp, D. Brooks, G. Searle, 2016, European Journal of Nuclear Medicine and Molecular Imaging.

GABAa receptor density alterations revealed in a mouse model of early moderate prenatal ethanol exposure using [18F]AH114726.

G. Cowin, G. Galloway, N. Kurniawan, 2020, Nuclear medicine and biology.

Novel fluorine-18 PET radiotracers based on flumazenil for GABAA imaging in the brain.

K. Linder, M. Kilbourn, P. Scott, 2013, Nuclear medicine and biology.

Gd3+ cFLFLFK conjugate for MRI: a targeted contrast agent for FPR1 in inflammation.

S. Luthra, M. Wylezinska-Arridge, J. Tremoleda, 2013, Chemical communications.

Ex Vivo Tracing of NMDA and GABA-A Receptors in Rat Brain After Traumatic Brain Injury Using 18F-GE-179 and 18F-GE-194 Autoradiography

A. Pitkänen, Anniina Snellman, M. Haaparanta-Solin, 2016, The Journal of Nuclear Medicine.