O. Eskola

发表

Neuroinflammation appears early and then plateaus in a mouse model of Alzheimer ’ s disease shown by PET imaging

S. Helin, J. Rinne, Anniina Snellman, 2017 .

Imaging perfusion and hypoxia with PET to predict radiotherapy response in head-and-neck cancer.

Tove Grönroos, Heikki Minn, Vesa Oikonen, 2004, International Journal of Radiation Oncology, Biology, Physics.

Effect of genotype and age on cerebral [18F]FDG uptake varies between transgenic APPSwe-PS1dE9 and Tg2576 mouse models of Alzheimer’s disease

J. Rinne, Anniina Snellman, M. Haaparanta-Solin, 2019, Scientific Reports.

Pharmacokinetics of [18F]FETNIM: A Potential Hypoxia Marker for PET

H. Minn, K. Lehtiö, T. Grönroos, 2001 .

Gender and age affect NK1 receptors in the human brain - a positron emission tomography study with [18F]SPA-RQ.

Jarmo Hietala, Richard Hargreaves, Olli Eskola, 2007, The international journal of neuropsychopharmacology.

[18F]SPA-RQ/PET Study of NK1 receptors in the Whole Body of Guinea Pig and Rat

J. Hietala, M. Haaparanta-Solin, E. Löyttyniemi, 2019, Scientific Reports.

ORIGINAL RESEARCH Open Access ( 18 F)CFT synthesis and binding to monoamine transporters in rats

T. Grönroos, M. Haaparanta, O. Solin, 2012 .

[18F]CFT synthesis and binding to monoamine transporters in rats

T. Grönroos, M. Haaparanta, O. Solin, 2012, EJNMMI Research.

Use of [18F]F−/[18F]F2 conversion in production of pet tracers for clinical use. An eight-year follow-up

T. Viljanen, M. Haaparanta, O. Solin, 2001 .

[(18)F]FDOPA and [(18)F]CFT are both sensitive PET markers to detect presynaptic dopaminergic hypofunction in early Parkinson's disease.

H. Ruottinen, J. Bergman, O. Solin, 2001, Synapse.

Free fatty acid uptake in the myocardium and skeletal muscle using fluorine-18-fluoro-6-thia-heptadecanoic acid.

V. Oikonen, J. Knuuti, P. Nuutila, 1998, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Prognostic value of tumour blood flow, [18F]EF5 and [18F]FDG PET/CT imaging in patients with head and neck cancer treated with radiochemotherapy

H. Sipilä, H. Minn, G. Komar, 2014, European Journal of Nuclear Medicine and Molecular Imaging.

Comparison of: (2S,4R)-4-[18F]Fluoroglutamine, [11C]Methionine, and 2-Deoxy-2-[18F]Fluoro-D-Glucose and Two Small-Animal PET/CT Systems Imaging Rat Gliomas

S. Helin, V. Oikonen, H. Minn, 2021, Frontiers in Oncology.

A Potential Hypoxia Marker for PET

H. Minn, T. Grönroos, M. Haaparanta, 2001 .

Influence of transport line material on the molar activity of cyclotron produced [18F]fluoride.

T. Viljanen, O. Solin, J. Bergman, 2018, Nuclear medicine and biology.

Hypoxia, blood flow and metabolism in squamous-cell carcinoma of the head and neck: correlations between multiple immunohistochemical parameters and PET

P. Kronqvist, H. Minn, R. Grenman, 2014, BMC Cancer.

Pharmacokinetics of [18F]FETNIM: a potential marker for PET.

H. Minn, K. Lehtiö, T. Grönroos, 2001, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Exercise training alters lipoprotein particles independent of brown adipose tissue metabolic activity

J. Hannukainen, P. Nuutila, L. Goodyear, 2019, Obesity science & practice.

Mortality in Parkinson's disease is not associated with the severity of early dopaminergic defect.

J. Rinne, J. Järvelä, V. Kaasinen, 2014, Parkinsonism & related disorders.

HYDROXYSTEROID (17β) DEHYDROGENASE 12 IS ESSENTIAL FOR THE METABOLIC HOMEOSTASIS IN ADULT MICE.

M. Poutanen, V. Velagapudi, A. Pessia, 2020, American journal of physiology. Endocrinology and metabolism.

Noninvasive diagnosis of focal hyperinsulinism of infancy with [18F]-DOPA positron emission tomography.

H. Huopio, M. Laakso, R. Parkkola, 2006, Diabetes.

Change in brain amyloid load and cognition in patients with amnestic mild cognitive impairment: a 3-year follow-up study

R. Parkkola, J. Rinne, J. Johansson, 2022, EJNMMI Research.

In vivo imaging of Lyme arthritis in mice by [18F]fluorodeoxyglucose positron emission tomography/computed tomography

M. Söderström, H. Liljenbäck, A. Roivainen, 2018, Scandinavian journal of rheumatology.

Electrophilic synthesis of 6-[18F]fluoro-L-DOPA using post-target produced [18F]F2

M. Haaparanta, O. Solin, S. Forsback, 2008 .

Positron Emission Tomography Imaging of Macrophages in Atherosclerosis with 18F-GE-180, a Radiotracer for Translocator Protein (TSPO)

J. Knuuti, S. Ylä-Herttuala, A. Saraste, 2018, Contrast media & molecular imaging.

Exploiting Glutamine Consumption in Atherosclerotic Lesions by Positron Emission Tomography Tracer (2S,4R)-4-18F-Fluoroglutamine

J. Knuuti, A. Saraste, M. Kaikkonen, 2022, Frontiers in Immunology.

Radiation dosimetry and biodistribution of the hypoxia tracer (18)F-EF5 in oncologic patients.

H. Minn, S. Hahn, C. Koch, 2012, Cancer biotherapy & radiopharmaceuticals.

Flare on [18F]PSMA-1007 PET/CT after short-term androgen deprivation therapy and its correlation to FDG uptake: possible marker of tumor aggressiveness in treatment-naïve metastatic prostate cancer patients

P. Boström, J. Kemppainen, S. Malaspina, 2022, European Journal of Nuclear Medicine and Molecular Imaging.

Undifferentiated sinonasal carcinoma may respond to single-fraction boron neutron capture therapy.

A. Paetau, S. Savolainen, J. Jääskeläinen, 2004, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

FLUORINE AND 18 F-FLUORINE IN RADIOPHARMACEUTICAL PREPARATION by

O. Eskola, 2013 .

A novel electrophilic synthesis and evaluation of medium specific radioactivity (1R,2S)-4-[18F]fluorometaraminol, a tracer for the assessment of cardiac sympathetic nerve integrity with PET.

C. Halldin, F. Dollé, O. Langer, 2004, Nuclear medicine and biology.

Automated synthesis and purification of [18F]bromofluoromethane at high specific radioactivity.

O. Solin, J. Bergman, P. Lehikoinen, 2001, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Short Communication Undifferentiated sinonasal carcinoma may respond to single-fraction boron neutron capture therapy

A. Paetau, S. Savolainen, H. Minn, 2004 .

Alternative solvents for electrophilic synthesis of 6‐[18F]fluoro‐L‐DOPA

M. Haaparanta, O. Solin, J. Bergman, 2009 .

Head-to-Head Comparison of 68Ga-Citrate and 18F-FDG PET/CT for Detection of Infectious Foci in Patients with Staphylococcus aureus Bacteraemia

P. Nuutila, J. Kemppainen, L. Pirilä, 2017, Contrast media & molecular imaging.

Synthesis of 3-[[4-(4-[18F] fluorophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine

T. Grönroos, M. Haaparanta, O. Solin, 2002 .

Fluorine and 18F-Fluorine in Radiopharmaceutical Preparation

O. Eskola, 2013 .

Increased frontal [(18)F]fluorodopa uptake in early Parkinson's disease: sex differences in the prefrontal cortex.

V Kaasinen, J O Rinne, A Brück, 2001, Brain : a journal of neurology.

Human positron emission tomography studies of brain neurokinin 1 receptor occupancy by aprepitant

Gunnar Antoni, Jarmo Hietala, Bengt Långström, 2004, Biological Psychiatry.

Visualization and Quantification of Neurokinin-1 (NK1) Receptors in the Human Brain

Päivi Marjamäki, Tove Grönroos, Merja Haaparanta, 2005, Molecular Imaging and Biology.

Novel effects of the gastrointestinal hormone secretin on cardiac metabolism and renal function

L. Nummenmaa, R. Klén, P. Nuutila, 2021, American journal of physiology. Endocrinology and metabolism.

Associations of sedentary time, physical activity, and fitness with muscle glucose uptake in adults with metabolic syndrome

T. Vasankari, J. Knuuti, H. Vähä-Ypyä, 2022, Scandinavian journal of medicine & science in sports.

Reproducibility and Effect of Levodopa on Dopamine Transporter Function Measurements: A [18F]CFT PET Study

J. Rinne, O. Solin, J. Bergman, 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Cessation of anti-VLA-4 therapy in a focal rat model of multiple sclerosis causes an increase in neuroinflammation

J. Rinne, L. Airas, J. Tuisku, 2019, EJNMMI Research.

Increased presynaptic dopamine function in Asperger syndrome

T. Autti, S. Aalto, J. Hietala, 2004, Neuroreport.

Uptake of 4-borono-2-[18F]fluoro-L-phenylalanine in sporadic and neurofibromatosis 2-related schwannoma and meningioma studied with PET

V. Oikonen, J. Jääskeläinen, H. Minn, 2006, European Journal of Nuclear Medicine and Molecular Imaging.

Comparison of the biodistribution of two hypoxia markers [18F]FETNIM and [18F]FMISO in an experimental mammary carcinoma

H. Minn, M. Horsman, R. Murata, 2004, European Journal of Nuclear Medicine and Molecular Imaging.

Synthesis of 4-dihydroxyboryl-2-[18F]fluorophenylalanine with relatively high-specific activity

J. Jääskeläinen, O. Solin, J. Bergman, 2002 .

Secretin activates brown fat and induces satiation

L. Elo, L. Nummenmaa, R. Klén, 2021, Nature Metabolism.

Monoacylglycerol lipase inhibitor JZL184 reduces neuroinflammatory response in APdE9 mice and in adult mouse glial cells

J. Rinne, M. Haaparanta-Solin, F. López-Picón, 2015, Journal of Neuroinflammation.

Altered dopamine D2 receptor binding in atypical facial pain

Kjell Någren, Juha O. Rinne, Sargo Aalto, 2003, Pain.

Prospective evaluation of 18F-FACBC PET/CT and PET/MRI versus multiparametric MRI in intermediate- to high-risk prostate cancer patients (FLUCIPRO trial)

H. Merisaari, Marko Pesola, P. Taimen, 2018, European Journal of Nuclear Medicine and Molecular Imaging.

Imaging of tumor hypoxia to predict treatment sensitivity.

H. Minn, G. Komar, K. Lehtiö, 2008, Current pharmaceutical design.

18F-EF5: A New PET Tracer for Imaging Hypoxia in Head and Neck Cancer

Marko Seppänen, Heikki Minn, Olli Eskola, 2008, Journal of Nuclear Medicine.

Seasonality of striatal dopamine synthesis capacity in Parkinson's disease

Juha O. Rinne, Juho Joutsa, Valtteri Kaasinen, 2012, Neuroscience Letters.

Amyloid-Targeting PET Tracer [18F]Flutemetamol Accumulates in Atherosclerotic Plaques

J. Knuuti, S. Ylä-Herttuala, A. Saraste, 2019, Molecules.

In vivo PET imaging of beta-amyloid deposition in mouse models of Alzheimer's disease with a high specific activity PET imaging agent [18F]flutemetamol

M. Scheinin, J. Rinne, G. Forloni, 2014, EJNMMI Research.

Hypoxia, blood flow and metabolism in squamous-cell carcinoma of the head and neck: correlations between multiple immunohistochemical parameters and PET

H. Minn, T. Viljanen, K. Lehtiö, 2014, BMC Cancer.

Quantifying tumour hypoxia with fluorine-18 fluoroerythronitroimidazole ([18F]FETNIM) and PET using the tumour to plasma ratio

Tove Grönroos, Heikki Minn, Vesa Oikonen, 2002, European Journal of Nuclear Medicine and Molecular Imaging.

Imaging of blood flow and hypoxia in head and neck cancer: initial evaluation with [(15)O]H(2)O and [(18)F]fluoroerythronitroimidazole PET.

V. Oikonen, H. Minn, P. Nuutila, 2001, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Positron emission tomography imaging of the serotonin transporter in the pig brain using [11C](+)‐McN5652 and S‐([18F]fluoromethyl)‐(+)‐McN5652

J. Steinbach, P. Brust, R. Hinz, 2003, Synapse.

S‐[18F]fluoromethyl‐(+)‐McN5652, a PET tracer for the serotonin transporter: Evaluation in rats

J. Steinbach, P. Brust, T. Grönroos, 2003, Synapse.

Pharmacokinetics of [18F]flutemetamol in wild-type rodents and its binding to beta amyloid deposits in a mouse model of Alzheimer’s disease

M. Scheinin, J. Rinne, G. Farrar, 2012, European Journal of Nuclear Medicine and Molecular Imaging.

In Vivo PET Imaging Demonstrates Diminished Microglial Activation After Fingolimod Treatment in an Animal Model of Multiple Sclerosis

J. Rinne, J. Johansson, L. Airas, 2015, The Journal of Nuclear Medicine.

Tracer Level Electrophilic Synthesis and Pharmacokinetics of the Hypoxia Tracer [18F]EF5

H. Minn, G. Komar, P. Härkönen, 2012, Molecular Imaging and Biology.

Personality traits and brain dopaminergic function in Parkinson's disease

Juha O. Rinne, Valtteri Kaasinen, Olli Eskola, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Gender and age affect NK 1 receptors in the human brain – a positron emission tomography study with [ 18 F ] SPARQ

J. Hietala, T. Vahlberg, R. Hargreaves, 2007 .

Reduced striatal dopamine synthesis capacity is associated with symptoms of depression in patients with de novo unmedicated Parkinson's disease.

J. Rinne, J. Joutsa, V. Kaasinen, 2013, Journal of Parkinson's disease.

Thermogenic Capacity of Human Supraclavicular Brown Fat and Cold-Stimulated Brain Glucose Metabolism

L. Nummenmaa, P. Nuutila, M. Klingenspor, 2023, Metabolites.

Brain energy metabolism and neuroinflammation in ageing APP/PS1-21 mice using longitudinal 18F-FDG and 18F-DPA-714 PET imaging

J. Rinne, M. Haaparanta-Solin, E. Löyttyniemi, 2017, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Gender and age affect NK1 receptors in the human brain - a positron emission tomography

J. Hietala, T. Vahlberg, R. Hargreaves, 2007 .

Effect of genotype and age on cerebral [18F]FDG uptake varies between transgenic APPSwe-PS1dE9 and Tg2576 mouse models of Alzheimer’s disease

J. Rinne, Anniina Snellman, M. Haaparanta-Solin, 2019, Scientific Reports.

Novel electrophilic synthesis of 6-[18F]fluorodopamine and comprehensive biological evaluation

J. Knuuti, J. Kišš, T. Grönroos, 2012, European Journal of Nuclear Medicine and Molecular Imaging.

Personality traits and striatal dopamine synthesis capacity in healthy subjects.

Jarmo Hietala, Aki Laakso, Esa Wallius, 2003, The American journal of psychiatry.

18F-Fluoroerythronitroimidazole radiation dosimetry in cancer studies.

V. Oikonen, H. Minn, K. Lehtiö, 2002, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Detection of response to COMT inhibition in FDOPA PET in advanced Parkinson's disease requires prolonged imaging

V. Oikonen, H. Ruottinen, O. Solin, 2001, Synapse.

Simple Ratio Analysis of 18F-Fluorodopa Uptake in Striatal Subregions Separates Patients with Early Parkinson Disease from Healthy Controls

A. Brück, J. Rinne, H. Helenius, 2009, Journal of Nuclear Medicine.

Progression of dopaminergic hypofunction in striatal subregions in Parkinson's disease using [18F]CFT PET

Juha O Rinne, Olli Eskola, J. Rinne, 2003, Synapse.

[18F]FDOPA and [18F]CFT are both sensitive PET markers to detect presynaptic dopaminergic hypofunction in early Parkinson's disease

Olli Eskola, H. Ruottinen, J. Bergman, 2001 .

Dimethyl fumarate decreases short-term but not long-term inflammation in a focal EAE model of neuroinflammation

J. Rinne, D. Anthony, L. Airas, 2022, EJNMMI Research.

Neuroinflammation Appears Early on PET Imaging and Then Plateaus in a Mouse Model of Alzheimer Disease

S. Helin, J. Rinne, Anniina Snellman, 2017, The Journal of Nuclear Medicine.

Positron emission tomography with [18F]flutemetamol and [11C]PiB for in vivo detection of cerebral cortical amyloid in normal pressure hydrocephalus patients

J. Huttunen, M. Kailajärvi, J. Rinne, 2013, European journal of neurology.

Synthesis of S-([18F]fluoromethyl)-(+)-McN5652 as a potential PET radioligand for the serotonin transporter.

J. Steinbach, P. Brust, B. Johannsen, 2001, Nuclear medicine and biology.

Comparison of 2β-Carbomethoxy-3β-(4-[18F]Fluorophenyl)Tropane and N-(3-[18F]Fluoropropyl)-2β-Carbomethoxy-3β-(4-Fluorophenyl)Nortropane, Tracers for Imaging Dopamine Transporter in Rat

T. Grönroos, M. Haaparanta, O. Solin, 2010, Molecular Imaging and Biology.

Synthesis and characterization of a potent, selective, radiolabeled substance-P antagonist for NK1 receptor quantitation: ([18F]SPA-RQ).

Tove Grönroos, Merja Haaparanta, Jarmo Hietala, 2004, Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging.

Uptake of 6‐[18F]fluoro‐L‐dopa and [18F]CFT reflect nigral neuronal loss in a rat model of Parkinson's disease

J. Rinne, T. Grönroos, M. Haaparanta, 2004, Synapse.

In vivo sampling for pharmacokinetic studies in small experimental animals: a combination of microdialysis, planar chromatography and digital autoradiography.

T. Grönroos, M. Haaparanta, O. Solin, 2004, Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging.

Planar chromatographic analysis and quantification of short-lived radioactive metabolites from microdialysis fractions.

T. Grönroos, M. Haaparanta, O. Solin, 2006, Journal of chromatography. A.

Brain neurokinin-1 receptor availability in never-medicated patients with major depression - A pilot study.

L. Nummenmaa, J. Hirvonen, J. Hietala, 2019, Journal of affective disorders.

Brain glucose metabolism and its relation to amyloid load in middle-aged adults with childhood-onset epilepsy

S. Helin, J. Rinne, S. Shinnar, 2017, Epilepsy Research.

Prediction of prostate cancer aggressiveness using 18F-Fluciclovine (FACBC) PET and multisequence multiparametric MRI

H. Merisaari, Marko Pesola, P. Taimen, 2020, Scientific Reports.