Alexandra Flemming

发表

Infectious disease: Unravelling SARS lethality

Alexandra Flemming, Alexandra Flemming, 2005, Nature Reviews Drug Discovery.

Apoptosis: New strategies to tip the BCL-2 balance

Alexandra Flemming, 2008, Nature Reviews Drug Discovery.

In this issue

Katie Kingwell, Timo Hannay, P. Kirkpatrick, 2016, Nature Reviews Drug Discovery.

In this issue

Sarah Crunkhorn, Timo Hannay, P. Kirkpatrick, 2008, Nature Reviews Drug Discovery.

Cancer: Oncolytic poxvirus homes in on cancer cells

Alexandra Flemming, 2011, Nature Reviews Drug Discovery.

CAR Ts BiTE in brain

Alexandra Flemming, 2019, Nature Reviews Immunology.

Cancer: Hope for smoking-associated lung cancer?

Alexandra Flemming, 2011, Nature Reviews Drug Discovery.

T cells: Successful checkpoint blockade requires positive co-stimulation

Alexandra Flemming, 2017, Nature Reviews Immunology.

Vaccines: Self-amplifying RNA in lipid nanoparticles: a next-generation vaccine?

Alexandra Flemming, 2012, Nature Reviews Drug Discovery.

Cancer: PD1 makes waves in anticancer immunotherapy

Alexandra Flemming, 2012, Nature reviews. Drug discovery.

Cancer: Epigenetic target in Hedgehog-driven tumours

Alexandra Flemming, 2014, Nature Reviews Drug Discovery.

Diabetes: Mobilizing regulatory T cells against type 1 diabetes

Alexandra Flemming, 2011, Nature Reviews Drug Discovery.

Cross reactive T cells hold up against Omicron

Alexandra Flemming, 2022, Nature Reviews Immunology.

Heart Failure: Targeting miRNA pathology in heart disease

Alexandra Flemming, 2014, Nature Reviews Drug Discovery.

Atmospheric scattering of energetic electrons from near-Earth space

R. Wirz, C. Shaffer, E. Grimes, 2021 .

A Conditional Knockout Mouse Model Reveals That Calponin-3 Is Dispensable for Early B Cell Development

H. Jumaa, Qi-Quan Huang, S. Herzog, 2015, PloS one.

Tumour vaccination: Devil in the details of adjuvant choice

Alexandra Flemming, 2013, Nature Reviews Drug Discovery.

Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop.

M. Reth, W. Schamel, Thomas Wossning, 2002, Molecular cell.

Tame or inflame: gut reactions to pro- and antibiotics

Alexandra Flemming, 2018, Nature Reviews Immunology.

Molecularly targeted therapy: JAK2 inhibitor restores balance in polycythaemia vera

Alexandra Flemming, 2008, Nature Reviews Drug Discovery.

Omicron, the great escape artist

Alexandra Flemming, 2022, Nature Reviews Immunology.

Cancer: An epigenetic target for synthetic lethality

Alexandra Flemming, 2015, Nature Reviews Drug Discovery.

Drug delivery: siRNA: brain delivery breakthrough

Alexandra Flemming, 2007, Nature Reviews Drug Discovery.

Drug techniques: siRNA: brain delivery breakthrough

Alexandra Flemming, 2007, Nature Reviews Neuroscience.

SARS-CoV-2 variant evades antibodies whilst maintaining fitness

Alexandra Flemming, 2021, Nature Reviews Immunology.

Are variant-specific vaccines warranted?

Alexandra Flemming, 2022, Nature reviews. Immunology.

Cancer: Tumour-specific ablation of Treg cells induces anticancer response

Alexandra Flemming, 2016, Nature Reviews Drug Discovery.

Protein kinase C δ is essential for optimal macrophage-mediated phagosomal containment of Listeria monocytogenes

Winston Hide, Reto Guler, Frank Brombacher, 2007, Proceedings of the National Academy of Sciences.

Fungal infection: JNK inhibitors boost antifungal immunity

Alexandra Flemming, 2017, Nature Reviews Immunology.

Deficiency of the adaptor SLP-65 in pre-B-cell acute lymphoblastic leukaemia

M. Schrappe, M. Reth, C. Niemeyer, 2003, Nature.

Cancer: Mutant p53 rescued by aggregation inhibitor

Alexandra Flemming, 2016, Nature Reviews Drug Discovery.

Identification of a Pre-BCR Lacking Surrogate Light Chain

M. Reth, H. Jumaa, E. Hobeika, 2003, The Journal of experimental medicine.

The adaptor protein SLP-65 acts as a tumor suppressor that limits pre-B cell expansion

M. Reth, T. Brummer, H. Jumaa, 2003, Nature Immunology.

Omicron alone provides limited cross-protection

Alexandra Flemming, 2022, Nature reviews. Immunology.

mRNA vaccine shows promise in autoimmunity

Alexandra Flemming, 2021, Nature reviews. Immunology.

Rejuvenation through checkpoint inhibitors?

Alexandra Flemming, 2022, Nature Reviews Immunology.

Butyrate boosts microbicidal macrophages

Alexandra Flemming, 2019, Nature Reviews Immunology.

Butyrate boosts microbicidal macrophages

Alexandra Flemming, 2019, Nature Reviews Immunology.

HIV: Sequential vaccine elicits broadly neutralizing antibodies

Alexandra Flemming, 2016, Nature Reviews Drug Discovery.

Do rogue antibodies make the difference between mild versus severe COVID-19?

Alexandra Flemming, 2021, Nature Reviews Immunology.

Cancer: Red chillies tackle tumours

Alexandra Flemming, 2007, Nature Reviews Drug Discovery.

Biotechnology: Human antibodies from chicken eggs

Alexandra Flemming, 2005, Nature reviews. Drug discovery.

The enigma of circular RNA

Alexandra Flemming, 2019, Nature Reviews Immunology.

Dectin-1 on colonic γδ T cells mediates vulnerability to psychosocial stress

Alexandra Flemming, 2023, Nature Reviews Immunology.

Single-cell atlases dissect tissue destruction by SARS-CoV-2

Alexandra Flemming, 2021, Nature Reviews Immunology.

Vaccines: HIV vaccine failure due to induction of immune suppressors?

Alexandra Flemming, 2014, Nature Reviews Drug Discovery.

GZMK+ T cells a hallmark of immune ageing

Alexandra Flemming, 2020, Nature reviews. Immunology.

Gut commensals promote antiviral immunity via extracellular vesicles

Alexandra Flemming, 2022, Nature Reviews Immunology.

Alzheimer’s disease: Aβ–fibrinogen interaction inhibitor improves cognition in AD

Alexandra Flemming, 2014, Nature Reviews Drug Discovery.

First glimpses into the mechanisms of Long COVID

Alexandra Flemming, 2022, Nature Reviews Immunology.

Neutrophil ferroptosis causes immunosuppression

Alexandra Flemming, 2022, Nature reviews. Immunology.

Autoimmunity: Nanoparticles engineered for antigen-specific immunotherapy

Alexandra Flemming, 2016, Nature Reviews Immunology.

Cancer stem cells: Targeting the root of cancer relapse

Alexandra Flemming, 2015, Nature Reviews Drug Discovery.

Poor nasal immunity can lead to severe COVID-19

Alexandra Flemming, 2021, Nature Reviews Immunology.

Autoimmune disease: New drug target for MS?

Alexandra Flemming, 2011, Nature Reviews Drug Discovery.

Therapeutics: Opening the door to a new class of proteasome inhibitors

Alexandra Flemming, 2011, Nature Reviews. Cancer.

Infectious disease: Topical microbicide based on siRNA

Alexandra Flemming, 2006, Nature Reviews Drug Discovery.

Cancer: New target for tumour immunotherapy

Alexandra Flemming, 2008, Nature Reviews Drug Discovery.

Deal watch: J&J and Genmab deal to push forward CD38 as a blood cancer target

Alexandra Flemming, 2012, Nature Reviews Drug Discovery.

Needles in a haystack: the quest for bnAbs

Alexandra Flemming, 2018 .

Pan-sarbecovirus mAb protects from variants

Alexandra Flemming, 2021, Nature Reviews Immunology.

Natural regulatory plasma cells

Alexandra Flemming, 2018, Nature Reviews Immunology.

Antibody engineering: Fine-tuning antibody–drug conjugates

Alexandra Flemming, 2014, Nature Reviews Drug Discovery.

Defective viral genomes can protect against SARS-CoV-2 variants and other respiratory viruses

Alexandra Flemming, 2021, Nature reviews. Immunology.

Tumour Immunology: LAP targeting reduces tolerogenic cells in cancer

Alexandra Flemming, 2017, Nature Reviews Immunology.

In Brief

Alexandra Flemming, 1918, Nature Reviews Neuroscience.

The Importance Of Fungi

Alexandra Flemming, 2006 .

Tumour heterogeneity determines immune response

Alexandra Flemming, 2019, Nature reviews. Immunology.

Recruited macrophages are culprits in atrial fibrillation

Alexandra Flemming, 2023, Nature Reviews Immunology.

Cross-reactive tissue-resident CD8+ T cells may provide first line of defence against SARS-CoV-2

Alexandra Flemming, 2021, Nature reviews. Immunology.

TH9 cells tackle advanced tumours

Alexandra Flemming, 2018, Nature Reviews Immunology.

Calming inflammation to prevent stroke damage

Alexandra Flemming, 2019, Nature Reviews Immunology.

Boosting cytotoxic T cells for immunotherapy

Alexandra Flemming, 2022, Nature Reviews Immunology.

Cancer: Re-educating tumour-associated macrophages

Alexandra Flemming, Alexandra Flemming, 2011, Nature Reviews Drug Discovery.

Intracranial inflammatory mediators involved in SARS-CoV-2 neurological manifestations?

Alexandra Flemming, 2021, Nature Reviews Immunology.

Cancer: Targeting mutant BRAF in metastatic melanoma

Alexandra Flemming, 2010, Nature Reviews Drug Discovery.

Tick-targeted mRNA vaccine to tackle disease transmission?

Alexandra Flemming, 2021, Nature Reviews Immunology.

Targeted therapy: RAS mimetic revealed

Alexandra Flemming, 2016, Nature Reviews Cancer.

Nanobiologic trains innate immunity for anticancer responses

Alexandra Flemming, 2020, Nature Reviews Immunology.

Host IgM facilitates mating in Leishmania

Alexandra Flemming, 2023, Nature Reviews Immunology.

Antivirals: Achilles heel of Ebola viral entry

Alexandra Flemming, 2011, Nature Reviews Drug Discovery.

Cancer: Bivalent mTOR inhibitors — the next generation

Alexandra Flemming, 2016, Nature reviews. Drug discovery.

NMDAR-directed CAAR T cells show promise for autoimmune encephalitis

Alexandra Flemming, 2023, Nature reviews. Immunology.

Anticancer drugs: Finding the perfect combination

Alexandra Flemming, Alexandra Flemming, 2014, Nature reviews. Drug discovery.

Shocking HIV out of hiding

Alexandra Flemming, 2020, Nature Reviews Drug Discovery.

Stroke: Can PSD95 inhibitors widen the therapeutic window?

Alexandra Flemming, 2012, Nature reviews. Drug discovery.

Cancer: Anti-CD73 slows tumour growth and spread

Alexandra Flemming, 2010, Nature Reviews Drug Discovery.