Asta Zubrienė

发表

Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases.

S. Gražulis, Lina Baranauskienė, V. Kairys, 2012, European journal of medicinal chemistry.

Crystal structure correlations with the intrinsic thermodynamics of human carbonic anhydrase inhibitor binding

S. Gražulis, D. Matulis, A. Smirnov, 2018, PeerJ.

Thermodynamic, kinetic, and structural parameterization of human carbonic anhydrase interactions toward enhanced inhibitor design

J. Ladbury, S. Gražulis, Lina Baranauskienė, 2018, Quarterly Reviews of Biophysics.

Novel fluorinated carbonic anhydrase IX inhibitors reduce hypoxia-induced acidification and clonogenic survival of cancer cells

P. Lambin, L. Dubois, K. Tārs, 2018, Oncotarget.

Beta and Gamma Amino Acid-Substituted Benzenesulfonamides as Inhibitors of Human Carbonic Anhydrases

S. Gražulis, V. Kairys, D. Matulis, 2022, Pharmaceuticals.

Switching the Inhibitor‐Enzyme Recognition Profile via Chimeric Carbonic Anhydrase XII

Wen-Yih Chen, J. Ladbury, S. Gražulis, 2021, ChemistryOpen.

Design and Synthesis of Hydrazone‐Bearing Benzenesulfonamides as Carbonic Anhydrase VB Inhibitors

D. Matulis, R. Vaickelionienė, Asta Zubrienė, 2021, ChemistrySelect.

Synthesis and structure-affinity relationship of chlorinated pyrrolidinone-bearing benzenesulfonamides as human carbonic anhydrase inhibitors.

D. Matulis, Asta Zubrienė, V. Mickevičius, 2020, Bioorganic chemistry.

Isoform-Selective Enzyme Inhibitors by Exploring Pocket Size According to the Lock-and-Key Principle.

A. Kazaks, K. Tārs, S. Gražulis, 2020, Biophysical journal.

Pyrrolidinone-bearing methylated and halogenated benzenesulfonamides as inhibitors of carbonic anhydrases.

D. Matulis, Asta Zubrienė, V. Mickevičius, 2019, Bioorganic & medicinal chemistry.

Characterization of Carbonic Anhydrase Thermal Stability

D. Matulis, Asta Zubrienė, 2019, Carbonic Anhydrase as Drug Target.

Observed Versus Intrinsic Thermodynamics of Inhibitor Binding to Carbonic Anhydrases

D. Matulis, Asta Zubrienė, 2019, Carbonic Anhydrase as Drug Target.

Thiazole-substituted benzenesulfonamides as inhibitors of 12 human carbonic anhydrases.

D. Matulis, E. Čapkauskaitė, Asta Zubrienė, 2018, Bioorganic chemistry.

Intrinsic Thermodynamics and Structure Correlation of Benzenesulfonamides with a Pyrimidine Moiety Binding to Carbonic Anhydrases I, II, VII, XII, and XIII

S. Gražulis, V. Kairys, D. Matulis, 2014, PloS one.

Characterization of human carbonic anhydrase XII stability and inhibitor binding.

D. Matulis, Asta Zubrienė, V. Michailovienė, 2013, Bioorganic & medicinal chemistry.

Benzenesulfonamides bearing pyrrolidinone moiety as inhibitors of carbonic anhydrase IX: synthesis and binding studies

D. Matulis, Asta Zubrienė, V. Mickevičius, 2016, Medicinal Chemistry Research.

Uncertainty in protein–ligand binding constants: asymmetric confidence intervals versus standard errors

O. Abián, A. Velázquez‐Campoy, Wen-Yih Chen, 2021, European Biophysics Journal.

Saccharin Sulfonamides as Inhibitors of Carbonic Anhydrases I, II, VII, XII, and XIII

Lina Baranauskienė, V. Kairys, D. Matulis, 2014, BioMed research international.

Maps of Correlations Between Compound Chemical Structures and Thermodynamics of Binding to 12 Human Carbonic Anhydrases: Towards Isoform-Selective Inhibitors

D. Matulis, Asta Zubrienė, V. Linkuvienė, 2019, Carbonic Anhydrase as Drug Target.

Intrinsic affinity of protein - Ligand binding by differential scanning calorimetry.

D. Matulis, Asta Zubrienė, V. Linkuvienė, 2022, Biochimica et biophysica acta. Proteins and proteomics.

Immobilized Alkaline Phosphatase for Molecular Cloning

Asta Zubrienė, G. Dienys, S. Budriene, 2002 .

Inhibitory effects of fluorinated benzenesulfonamides on insulin fibrillation.

D. Otzen, B. Schiøtt, D. Matulis, 2022, International journal of biological macromolecules.

Functionalization of Fluorinated Benzenesulfonamides and Their Inhibitory Properties toward Carbonic Anhydrases

S. Gražulis, D. Matulis, A. Smirnov, 2015, ChemMedChem.

Propionate Analogues of Zearalenone Bind to Hsp90

S. Knapp, O. Fedorov, D. Matulis, 2009, Chembiochem : a European journal of chemical biology.

Intrinsic thermodynamics of 4-substituted-2,3,5,6-tetrafluorobenzenesulfonamide binding to carbonic anhydrases by isothermal titration calorimetry.

S. Gražulis, D. Matulis, A. Smirnov, 2015, Biophysical chemistry.

Benzenesulfonamides with pyrimidine moiety as inhibitors of human carbonic anhydrases I, II, VI, VII, XII, and XIII.

S. Gražulis, D. Matulis, A. Smirnov, 2013, Bioorganic & medicinal chemistry.

N-Sulfamoylphenyl- and N-sulfamoylphenyl-N-thiazolyl-β-alanines and their derivatives as inhibitors of human carbonic anhydrases.

D. Matulis, Asta Zubrienė, V. Mickevičius, 2017, Bioorganic chemistry.

Probing the influence of an allylic methyl group in zearalenone analogues on binding to Hsp90.

D. Matulis, F. Sasse, M. Maier, 2010, Chemistry.

Uncertainty in protein–ligand binding constants: asymmetric confidence intervals versus standard errors

O. Abián, A. Velázquez‐Campoy, M. J. Moreno, 2021, European Biophysics Journal.

Intrinsic Thermodynamics of Protein-Ligand Binding by Isothermal Titration Calorimetry as Aid to Drug Design.

J. Ladbury, D. Matulis, Asta Zubrienė, 2019, Methods in molecular biology.

Measurement of Nanomolar Dissociation Constants by Titration Calorimetry and Thermal Shift Assay – Radicicol Binding to Hsp90 and Ethoxzolamide Binding to CAII

Lina Baranauskienė, J. Matulienė, D. Matulis, 2009, International journal of molecular sciences.

Intrinsic Thermodynamics and Structures of 2,4‐ and 3,4‐Substituted Fluorinated Benzenesulfonamides Binding to Carbonic Anhydrases

S. Gražulis, J. Matulienė, D. Matulis, 2017, ChemMedChem.

Benzenesulfonamides bearing pyrrolidinone moiety as inhibitors of carbonic anhydrase IX: synthesis and binding studies

D. Matulis, Asta Zubrienė, V. Mickevičius, 2016, Medicinal Chemistry Research.

4-Amino-substituted Benzenesulfonamides as Inhibitors of Human Carbonic Anhydrases

S. Gražulis, D. Matulis, A. Smirnov, 2014, Molecules.

Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV

W. Sly, E. Di Cera, Zhiwei Chen, 2018, European Biophysics Journal.

Structure and mechanism of secondary sulfonamide binding to carbonic anhydrases

S. Gražulis, V. Kairys, D. Matulis, 2021, European Biophysics Journal.

Picomolar fluorescent probes for compound affinity determination to carbonic anhydrase IX expressed in live cancer cells

L. Dubois, Lina Baranauskienė, J. Matulienė, 2022, Scientific Reports.

Benzenesulfonamides with benzimidazole moieties as inhibitors of carbonic anhydrases I, II, VII, XII and XIII

D. Matulis, E. Čapkauskaitė, Asta Zubrienė, 2014, Journal of enzyme inhibition and medicinal chemistry.

4-Substituted-2,3,5,6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII.

S. Gražulis, D. Matulis, A. Smirnov, 2013, Bioorganic & medicinal chemistry.

β-Galactosidase from Penicillium canescens. Properties and immobilization

Asta Zubrienė, G. Dienys, S. Budriene, 2005 .

Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX.

J. Ladbury, S. Gražulis, Lina Baranauskienė, 2014, Journal of medicinal chemistry.

Thermodynamics of radicicol binding to human Hsp90 alpha and beta isoforms.

Č. Venclovas, M. Gutkowska, M. Żylicz, 2010, Biophysical chemistry.

Discovery and Validation of SIRT2 Inhibitors Based on Tenovin-6: Use of a 1H-NMR Method to Assess Deacetylase Activity

L. Major, N. Westwood, S. Laín, 2012, Molecules.

Inhibitor Binding to Carbonic Anhydrases by Isothermal Titration Calorimetry

Wen-Yih Chen, J. Ladbury, S. Keller, 2019, Carbonic Anhydrase as Drug Target.

5-Benzylidene-hydantoin is a new scaffold for SIRT inhibition: From virtual screening to activity assays.

Giuseppe Marco Randazzo, P. Carrupt, C. Petit, 2016, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

PLBD: protein–ligand binding database of thermodynamic and kinetic intrinsic parameters

H. Schiöth, J. Ladbury, S. Gražulis, 2023, Database J. Biol. Databases Curation.

Selective DNA Gyrase Inhibitors: Multi-Target in Silico Profiling with 3D-Pharmacophores

Ž. Skok, J. Ilaš, S. Pajk, 2021, Pharmaceuticals.

Thermodynamic characterization of human carbonic anhydrase VB stability and intrinsic binding of compounds

Lina Baranauskienė, D. Matulis, Asta Zubrienė, 2016, Journal of Thermal Analysis and Calorimetry.

Synthesis and HDAC inhibitory activity of pyrimidine-based hydroxamic acids

D. Matulis, F. Meyer‐Almes, Asta Zubrienė, 2022, Beilstein journal of organic chemistry.

Use of native and immobilized β-galactosidase in the food industry

Asta Zubrienė, J. Sereikaitė, G. Dienys, 2000 .

Biphenyl substituted lysine derivatives as recognition elements for the matrix metalloproteinases MMP-2 and MMP-9.

V. Kairys, D. Matulis, A. Kirchhain, 2021, Bioorganic chemistry.

Intrinsic thermodynamics of sulfonamide inhibitor binding to human carbonic anhydrases I and II

Lina Baranauskienė, D. Matulis, Asta Zubrienė, 2015, Journal of enzyme inhibition and medicinal chemistry.

Thermal shift assay for protein–ligand dissociation constant determination

Lina Baranauskienė, D. Matulis, Asta Zubrienė, 2023, TrAC Trends in Analytical Chemistry.

Inhibitor Binding to Carbonic Anhydrases by Fluorescent Thermal Shift Assay

D. Matulis, Asta Zubrienė, V. Petrauskas, 2019, Carbonic Anhydrase as Drug Target.