M. Tanc

发表

Isatin-pyrazole benzenesulfonamide hybrids potently inhibit tumor-associated carbonic anhydrase isoforms IX and XII.

C. Supuran, H. Abdel‐Aziz, S. M. Abou-Seri, 2015, European journal of medicinal chemistry.

6-Substituted sulfocoumarins are selective carbonic anhdydrase IX and XII inhibitors with significant cytotoxicity against colorectal cancer cells.

C. Supuran, C. Ghelardini, L. di Cesare Mannelli, 2015, Journal of medicinal chemistry.

Microwave assisted synthesis of novel tetrazole/sulfonamide derivatives based on octahydroacridine, xanthene and chromene skeletons as inhibitors of the carbonic anhydrases isoforms I, II, IV and VII.

C. Supuran, M. Tanc, M. Kaya, 2017, Bioorganic & medicinal chemistry letters.

Mechanisms of action of carbonic anhydrase inhibitors

A. Angeli, M. Tanc, M. Bozdağ, 2019, Carbonic Anhydrases.

Effective Access to Multivalent Inhibitors of Carbonic Anhydrases Promoted by Peptide Bioconjugation.

C. Supuran, J. Winum, S. Ulrich, 2017, Chemistry.

Fluorinated pyrrolidines and piperidines incorporating tertiary benzenesulfonamide moieties are selective carbonic anhydrase II inhibitors

C. Supuran, M. Tanc, S. Thibaudeau, 2015, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and carbonic anhydrase inhibitory properties of sulfamides structurally related to dopamine.

C. Supuran, D. Vullo, I. Gülçin, 2013, Bioorganic & medicinal chemistry.

3-Hydroxy-1H-quinazoline-2,4-dione as a New Scaffold To Develop Potent and Selective Inhibitors of the Tumor-Associated Carbonic Anhydrases IX and XII.

C. Supuran, C. Ghelardini, A. Angeli, 2017, Journal of medicinal chemistry.

5-Aryl-1H-pyrazole-3-carboxylic acids as selective inhibitors of human carbonic anhydrases IX and XII.

C. Supuran, I. Juranić, B. Drakulić, 2015, Bioorganic & medicinal chemistry.

6-Substituted 1,2-benzoxathiine-2,2-dioxides are isoform-selective inhibitors of human carbonic anhydrases IX, XII and VA.

C. Supuran, A. Scozzafava, F. Carta, 2015, Organic & biomolecular chemistry.

Synthesis of novel acridine and bis acridine sulfonamides with effective inhibitory activity against the cytosolic carbonic anhydrase isoforms II and VII.

C. Supuran, M. Tanc, M. Bülbül, 2013, Bioorganic & medicinal chemistry.

7-Substituted-sulfocoumarins are isoform-selective, potent carbonic anhydrase II inhibitors.

C. Supuran, A. Scozzafava, F. Carta, 2013, Bioorganic & medicinal chemistry.

Synthesis and evaluation of novel benzotropolones as Atg4B inhibiting autophagy blockers.

G. D. De Meyer, W. Martinet, A. Kurdi, 2019, Bioorganic chemistry.

Dominant behaviours in the expression of human carbonic anhydrase hCA I activity.

C. Supuran, J. Winum, M. Barboiu, 2014, Chemical communications.

Synthesis and carbonic anhydrase inhibitory properties of amino acid – coumarin/quinolinone conjugates incorporating glycine, alanine and phenylalanine moieties

C. Supuran, M. Tanc, F. Küçükbay, 2016, Journal of enzyme inhibition and medicinal chemistry.

Synthesis of novel 5-amino-1,3,4-thiadiazole-2-sulfonamide containing acridine sulfonamide/carboxamide compounds and investigation of their inhibition effects on human carbonic anhydrase I, II, IV and VII.

C. Supuran, M. Tanc, M. Kaya, 2018, Bioorganic chemistry.

Microwave assisted synthesis of novel acridine-acetazolamide conjugates and investigation of their inhibition effects on human carbonic anhydrase isoforms hCA I, II, IV and VII.

C. Supuran, M. Tanc, M. Kaya, 2016, Bioorganic & medicinal chemistry.

Synthesis and carbonic anhydrase isoenzymes I, II, IX, and XII inhibitory effects of dimethoxybromophenol derivatives incorporating cyclopropane moieties.

C. Supuran, I. Gülçin, M. Topal, 2015, Journal of medicinal chemistry.

Synthesis of novel acridine bis-sulfonamides with effective inhibitory activity against the carbonic anhydrase isoforms I, II, IX and XII.

C. Supuran, M. Tanc, M. Kaya, 2015, Bioorganic & medicinal chemistry.

Synthesis of 6-tetrazolyl-substituted sulfocoumarins acting as highly potent and selective inhibitors of the tumor-associated carbonic anhydrase isoforms IX and XII.

C. Supuran, M. Tanc, A. Grandane, 2014, Bioorganic & medicinal chemistry.

Synthesis of 6-aryl-substituted sulfocoumarins and investigation of their carbonic anhydrase inhibitory action.

C. Supuran, M. Tanc, A. Grandane, 2015, Bioorganic & medicinal chemistry.

5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: solution and X-ray crystallographic studies.

C. Supuran, K. Tārs, M. Tanc, 2013, Bioorganic & medicinal chemistry.

Inhibitory effects of benzimidazole containing new phenolic Mannich bases on human carbonic anhydrase isoforms hCA I and II

C. Supuran, H. Gul, M. Tanc, 2016, Journal of enzyme inhibition and medicinal chemistry.

CO2-capture by engineered mammalian carbonic anhydrases

A. Nocentini, M. Tanc, Muhammet Tanc, 2019, Carbonic Anhydrases.

9,10‐Dibromo‐N‐aryl‐9,10‐dihydro‐9,10‐[3,4]epipyrroloanthracene‐12,14‐diones: Synthesis and Investigation of Their Effects on Carbonic Anhydrase Isozymes I, II, IX, and XII

C. Supuran, H. Göksu, I. Gülçin, 2016, Archiv der Pharmazie.

Carbonic anhydrase inhibitors: synthesis and inhibition of the human carbonic anhydrase isoforms I, II, IX and XII with benzene sulfonamides incorporating 4- and 3-nitrophthalimide moieties.

C. Supuran, F. Carta, M. Tanc, 2014, Bioorganic & medicinal chemistry.

Carbonic anhydrase inhibitors: synthesis and inhibition of the human carbonic anhydrase isoforms I, II, VII, IX and XII with benzene sulfonamides incorporating 4,5,6,7-tetrabromophthalimide moiety.

C. Supuran, F. Carta, M. Tanc, 2013, Bioorganic & medicinal chemistry.

ATG4B Inhibitor UAMC-2526 Potentiates the Chemotherapeutic Effect of Gemcitabine in a Panc02 Mouse Model of Pancreatic Ductal Adenocarcinoma

G. D. De Meyer, W. Martinet, S. Stroobants, 2021, Frontiers in Oncology.

Synthesis, structure and properties of N-aminosaccharin - A selective inhibitor of human carbonic anhydrase I

C. Supuran, M. Kuznetsov, M. Zibinsky, 2017 .

6-Triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrases IX and XII.

C. Supuran, M. Tanc, A. Grandane, 2014, Bioorganic & medicinal chemistry letters.

X-ray crystallographic and kinetic investigations of 6-sulfamoyl-saccharin as a carbonic anhydrase inhibitor.

V. Alterio, A. Di Fiore, G. De Simone, 2015, Organic & biomolecular chemistry.

Deciphering the Mechanism of Human Carbonic Anhydrases Inhibition with Sulfocoumarins: Computational and Experimental Studies.

C. Supuran, F. Carta, A. Nocentini, 2018, Chemistry.

Multimeric xanthates as carbonic anhydrase inhibitors

C. Supuran, M. Tanc, S. Vincent, 2016, Journal of enzyme inhibition and medicinal chemistry.

Exploring carbonic anhydrase inhibition with multimeric coumarins displayed on a fullerene scaffold.

C. Supuran, M. Tanc, S. Vincent, 2015, Organic & biomolecular chemistry.

6‐Triazolyl‐Substituted Sulfocoumarins Are Potent, Selective Inhibitors of the Tumor‐Associated Carbonic Anhydrases IX and XII.

C. Supuran, M. Tanc, A. Grandane, 2014 .

A class of carbonic anhydrase I – selective activators

C. Supuran, I. Kocsis, M. Barboiu, 2016, Journal of enzyme inhibition and medicinal chemistry.

Isoform-selective inhibitory profile of 2-imidazoline-substituted benzene sulfonamides against a panel of human carbonic anhydrases

C. Supuran, M. Tanc, S. Kalinin, 2016, Journal of enzyme inhibition and medicinal chemistry.

α-Carbonic Anhydrases Possess Thioesterase Activity.

C. Supuran, A. Scozzafava, F. Carta, 2015, ACS medicinal chemistry letters.

X-ray crystallography-promoted drug design of carbonic anhydrase inhibitors.

C. Supuran, A. Kazaks, K. Tārs, 2015, Chemical communications.

Synthesis and carbonic anhydrase I, II, IV and XII inhibitory properties of N-protected amino acid – sulfonamide conjugates

C. Supuran, M. Tanc, F. Küçükbay, 2016, Journal of enzyme inhibition and medicinal chemistry.

Primary mono- and bis-sulfonamides obtained via regiospecific sulfochlorination of N-arylpyrazoles: inhibition profile against a panel of human carbonic anhydrases

C. Supuran, T. Tuccinardi, M. Tanc, 2017, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and bioactivity studies of 1-aryl-3-(2-hydroxyethylthio)-1-propanones

C. Supuran, H. Sakagami, H. Gul, 2016, Journal of enzyme inhibition and medicinal chemistry.

Human carbonic anhydrase inhibitory profile of mono- and bis-sulfonamides synthesized via a direct sulfochlorination of 3- and 4-(hetero)arylisoxazol-5-amine scaffolds.

C. Supuran, T. Tuccinardi, M. Tanc, 2017, Bioorganic & medicinal chemistry.

Synthesis, characterization and carbonic anhydrase inhibitory activity of novel benzothiazole derivatives

C. Supuran, M. Tanc, Nesrin Buğday, 2016, Journal of enzyme inhibition and medicinal chemistry.

The Chicken Chorioallantoic Membrane as a Low-Cost, High-Throughput Model for Cancer Imaging

A. Herrmann, R. Southworth, T. Witney, 2023, bioRxiv.

Carbonic anhydrase inhibition and cytotoxicity studies of Mannich base derivatives of thymol

C. Supuran, C. Yamali, H. Sakagami, 2016, Journal of enzyme inhibition and medicinal chemistry.

The inhibitory effects of phenolic Mannich bases on carbonic anhydrase I and II isoenzymes

C. Supuran, C. Yamali, H. Gul, 2016, Journal of enzyme inhibition and medicinal chemistry.

In Vitro and In Situ Activity-Based Labeling of Fibroblast Activation Protein with UAMC1110-Derived Probes

O. De Wever, A. Lambeir, I. De Meester, 2021, Frontiers in Chemistry.