A. Grandane

发表

6-Substituted sulfocoumarins are selective carbonic anhdydrase IX and XII inhibitors with significant cytotoxicity against colorectal cancer cells.

C. Supuran, C. Ghelardini, L. di Cesare Mannelli, 2015, Journal of medicinal chemistry.

Long-Chain Acylcarnitines Decrease the Phosphorylation of the Insulin Receptor at Tyr1151 Through a PTP1B-Dependent Mechanism

E. Liepinsh, M. Dambrova, A. Grandane, 2021, International journal of molecular sciences.

Benzoxepinones: A new isoform-selective class of tumor associated carbonic anhydrase inhibitors.

C. Supuran, A. Nocentini, T. Werner, 2020, Bioorganic & medicinal chemistry.

Binding versus Enzymatic Processing of ε-Trimethyllysine Dioxygenase Substrate Analogues

P. Arsenyan, E. Liepinsh, A. Grandane, 2022, ACS Medicinal Chemistry Letters.

Facile synthesis of coumarin bioisosteres—1,2-benzoxathiine 2,2-dioxides

S. Belyakov, P. Trapencieris, A. Grandane, 2012 .

Sulfocoumarins (1,2-benzoxathiine-2,2-dioxides): a class of potent and isoform-selective inhibitors of tumor-associated carbonic anhydrases.

C. Supuran, A. Scozzafava, D. Vullo, 2013, Journal of medicinal chemistry.

Synthesis of 6-tetrazolyl-substituted sulfocoumarins acting as highly potent and selective inhibitors of the tumor-associated carbonic anhydrase isoforms IX and XII.

C. Supuran, M. Tanc, A. Grandane, 2014, Bioorganic & medicinal chemistry.

Development of oxathiino[6,5-b]pyridine 2,2-dioxide derivatives as selective inhibitors of tumor-related carbonic anhydrases IX and XII.

C. Supuran, A. Nocentini, A. Grandane, 2020, European journal of medicinal chemistry.

Synthesis of 6-aryl-substituted sulfocoumarins and investigation of their carbonic anhydrase inhibitory action.

C. Supuran, M. Tanc, A. Grandane, 2015, Bioorganic & medicinal chemistry.

Base-Free Catalytic Wittig-/Cross-Coupling Reaction Sequence as Short Synthetic Strategy for the Preparation of Highly Functionalized Arylbenzoxepinones

T. Werner, A. Grandane, R. Žalubovskis, 2021, Synthesis.

Intramolecular Base-Free Catalytic Wittig Reaction: Synthesis of Benzoxepinones.

H. Murua Escobar, C. Junghanss, Lars Longwitz, 2019, The Journal of organic chemistry.

6-Triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrases IX and XII.

C. Supuran, M. Tanc, A. Grandane, 2014, Bioorganic & medicinal chemistry letters.

Sulfocoumarins as dual inhibitors of human carbonic anhydrase isoforms IX/XII and of human thioredoxin reductase

C. Supuran, A. Grandane, R. Žalubovskis, 2020, Journal of enzyme inhibition and medicinal chemistry.

6‐Triazolyl‐Substituted Sulfocoumarins Are Potent, Selective Inhibitors of the Tumor‐Associated Carbonic Anhydrases IX and XII.

C. Supuran, M. Tanc, A. Grandane, 2014 .