H. Nakajima

发表

FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases.

Minoru Yoshida, Hidenori Nakajima, Akito Tanaka, 2002, Cancer research.

Amplification of transgene expression in vitro and in vivo using a novel inhibitor of histone deacetylase.

T. Yamano, Y. Kaneda, M. Monden, 2000, Molecular therapy : the journal of the American Society of Gene Therapy.

Signal therapy of breast cancers by the HDAC inhibitor FK228 that blocks the activation of PAK1 and abrogates the tamoxifen-resistance

J. Zalcberg, H. Nakajima, Y. Hirokawa, 2005, Cancer biology & therapy.

The novel gluconeogenesis inhibitors FR225659 and related compounds that originate from Helicomyces sp. No. 19353. II. Biological profiles.

M. Hino, H. Nakajima, Y. Ohtsu, 2003, The Journal of antibiotics.

Inhibition of hypoxia-induced angiogenesis by FK228, a specific histone deacetylase inhibitor, via suppression of HIF-1alpha activity.

Kyu-Won Kim, Se-Hee Kim, H. Nakajima, 2003, Biochemical and biophysical research communications.

FERMENTATION , ISOLATION , PHYSICO-CHEMICAL AND BIOLOGICAL PROPERTIES , AND ANTITUMOR ACTIVITY

M. Okuhara, H. Nakajima, T. Goto, 2006 .

FR180204, a novel and selective inhibitor of extracellular signal-regulated kinase, ameliorates collagen-induced arthritis in mice

H. Nakajima, M. Ohori, H. Miyake, 2006, Naunyn-Schmiedeberg's Archives of Pharmacology.

The Novel Gluconeogenesis Inhibitor FR225654 that Originates from Phoma sp. No. 00144

M. Hino, H. Nakajima, Y. Ohtsu, 2005, The Journal of Antibiotics.

The Novel Gluconeogenesis Inhibitor FR225654 that Originates from Phoma sp. No. 00144

M. Hino, H. Nakajima, Y. Ohtsu, 2005, The Journal of Antibiotics.

A putative role for histone deacetylase in the differentiation of human erythroid cells.

Y. Sugimoto, Kazuhiro Nishi, H. Shiku, 2005, International journal of oncology.

How and why was a histone deacetylase inhibitor created?

H. Nakajima, 2008, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

FK 228 ( Depsipeptide ) as a Natural Prodrug That Inhibits Class I Histone Deacetylases 1

M. Nishiyama, S. Horinouchi, Minoru Yoshida, 2002 .

A new antimitotic substance, FR182877. II. The mechanism of action.

M. Hino, H. Nakajima, H. Terano, 2000, The Journal of antibiotics.

Expression, purification, crystallization and preliminary X-ray diffraction studies of human liver regucalcin.

T. Kinoshita, T. Fujii, H. Nakajima, 2004, Acta crystallographica. Section D, Biological crystallography.

Cloning, expression, purification, crystallization and preliminary X-ray analysis of human liver glyceraldehyde-3-phosphate dehydrogenase.

T. Kinoshita, T. Fujii, H. Nakajima, 2004, Acta crystallographica. Section D, Biological crystallography.

New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of action.

M. Okuhara, H. Nakajima, H. Terano, 1996, The Journal of antibiotics.

New Antitumor Substances, FR901463, FR901464 and FR901465

M. Okuhara, H. Nakajima, H. Terano, 1996 .

The Novel Gluconeogenesis Inhibitor FR225654 that Originates from Phoma sp. No. 00144

T. Kinoshita, H. Nakajima, Y. Ohtsu, 2005, The Journal of Antibiotics.

FR901228, a potent antitumor antibiotic, is a novel histone deacetylase inhibitor.

M. Yoshida, S. Horinouchi, Minoru Yoshida, 1998, Experimental cell research.

FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties, and antitumor activity.

M. Okuhara, H. Nakajima, T. Goto, 1994, The Journal of antibiotics.

New antitumor substances, FR901463, FR901464 and FR901465. III. Structures of FR901463, FR901464 and FR901465.

H. Tanaka, H. Nakajima, H. Terano, 1997, The Journal of antibiotics.

New Antitumor Substances, FR901463, FR901464, and FR901465. Part 3. Structures of FR901463, FR901464, and FR901465.

H. Nakajima, Hirokazu Tanaka, H. Terano, 1997 .

Anti-herpes virus activity of polyether antibiotic CP-44161 in vivo

M. Hino, A. Fujie, H. Nakajima, 2009, The Journal of Antibiotics.

Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA

M. Hagiwara, S. Horinouchi, Minoru Yoshida, 2007, Nature Chemical Biology.

Inhibition of splicing and nuclear retention of pre-mRNA by spliceostatin A in fission yeast.

H. Taoka, S. Horinouchi, Minoru Yoshida, 2007, Biochemical and biophysical research communications.

FR177391, A New Anti-hyperlipidemic Agent from Serratia

T. Kinoshita, H. Nakajima, H. Terano, 2005, The Journal of Antibiotics.

FR177391, A New Anti-hyperlipidemic Agent from Serratia

H. Nakajima, M. Ohkubo, T. Fujii, 2005, The Journal of Antibiotics.

Action of FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum no. 968, on Ha-ras transformed NIH3T3 cells.

M. Okuhara, H. Nakajima, T. Goto, 1994, Bioscience, biotechnology, and biochemistry.

Histone deacetylase inhibitor FK228 inhibits tumor angiogenesis

H. Kwon, Kyu-Won Kim, H. Nakajima, 2002, International journal of cancer.

Identification of a selective ERK inhibitor and structural determination of the inhibitor-ERK2 complex.

T. Kinoshita, S. Nishimura, M. Neya, 2005, Biochemical and biophysical research communications.

A new antitumor antibiotic, FR900840. I. Discovery, identification, isolation and characterization.

H. Nakada, M. Okuhara, H. Nakajima, 1989, The Journal of antibiotics.

[A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p].

Hidenori Nakajima, H. Nakajima, 2007, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.

WS9761 A and B: new non-steroidal androgen-receptor antagonists produced by a Streptomyces.

M. Okuhara, H. Nakajima, T. Goto, 1993, The Journal of antibiotics.

FR177391, A New Anti-hyperlipidemic Agent from Serratia

H. Nakajima, M. Ohkubo, T. Fujii, 2005, The Journal of Antibiotics.

Role of a cysteine residue in the active site of ERK and the MAPKK family.

Seiji Yoshimura, Hidenori Nakajima, Takayoshi Kinoshita, 2007, Biochemical and biophysical research communications.

New antitumor substances, FR901463, FR901464 and FR901465. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities.

M. Okuhara, H. Nakajima, H. Terano, 1997, The Journal of antibiotics.

A selective detection of lysophosphatidylcholine in dried blood spots for diagnosis of adrenoleukodystrophy by LC-MS/MS

T. Okuyama, M. Kosuga, R. Mashima, 2016, Molecular genetics and metabolism reports.

Signal therapy of NF1-deficient tumor xenograft in mice by the anti-PAK1 drug FK228

A. Kurtz, V. Mautner, C. Hanemann, 2005, Cancer biology & therapy.

Generation of robust vascular networks from cardiovascular blast populations derived from human induced pluripotent stem cells in vivo and ex vivo organ culture system.

Yoshifumi Kobayashi, H. Nakajima, Tatsuya Kawamoto, 2013, Biochemical and biophysical research communications.

Structure of a high-resolution crystal form of human triosephosphate isomerase: improvement of crystals using the gel-tube method.

Hidenori Nakajima, Takayoshi Kinoshita, Shintaro Nishimura, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.