Bernadette Breiden

发表

Membrane lipids regulate ganglioside GM2 catabolism and GM2 activator protein activity[S]

G. Schwarzmann, K. Sandhoff, Susi Anheuser, 2015, Journal of Lipid Research.

Ganglioside GM2 catabolism is inhibited by storage compounds of mucopolysaccharidoses and by cationic amphiphilic drugs.

K. Sandhoff, Susi Anheuser, Bernadette Breiden, 2019, Molecular genetics and metabolism.

Emerging mechanisms of drug-induced phospholipidosis

K. Sandhoff, Bernadette Breiden, 2019, Biological chemistry.

Saposin A Mobilizes Lipids from Low Cholesterol and High Bis(monoacylglycerol)phosphate-containing Membranes

Ralf Klingenstein, Wolfram Saenger, W. Saenger, 2006, Journal of Biological Chemistry.

Acid Sphingomyelinase, a Lysosomal and Secretory Phospholipase C, Is Key for Cellular Phospholipid Catabolism

K. Sandhoff, Bernadette Breiden, 2021, International journal of molecular sciences.

Mechanism of Secondary Ganglioside and Lipid Accumulation in Lysosomal Disease

K. Sandhoff, Bernadette Breiden, 2020, International journal of molecular sciences.

Membrane lipids and their degradation compounds control GM2 catabolism at intralysosomal luminal vesicles

K. Sandhoff, Susi Anheuser, Bernadette Breiden, 2019, Journal of Lipid Research.

Ganglioside Metabolism and Its Inherited Diseases.

K. Sandhoff, Bernadette Breiden, 2018, Methods in molecular biology.

Lipids regulate the hydrolysis of membrane bound glucosylceramide by lysosomal β-glucocerebrosidase

G. Schwarzmann, K. Sandhoff, Bernadette Breiden, 2017, Journal of Lipid Research.

Synthetic Glycoforms Reveal Carbohydrate-Dependent Bioactivity of Human Saposin D.

M. Weyand, C. Steegborn, C. Heinlein, 2017, Angewandte Chemie.

Acid sphingomyelinase activity is regulated by membrane lipids and facilitates cholesterol transfer by NPC2

K. Sandhoff, J. Babalola, V. O. Oninla, 2014, Journal of Lipid Research.

Regulation of the NPC2 protein‐mediated cholesterol trafficking by membrane lipids

K. Sandhoff, Bernadette Breiden, Hichem D. Gallala, 2011, Journal of neurochemistry.

Role of endosomal membrane lipids and NPC2 in cholesterol transfer and membrane fusion[S]

G. Schwarzmann, K. Sandhoff, J. Babalola, 2010, Journal of Lipid Research.

The roles of endosomal membrane lipids and NPC 2 in cholesterol transfer and membrane fusion

G. Schwarzmann, K. Sandhoff, J. Babalola, 2010 .

Saposin B-dependent Reconstitution of Arylsulfatase A Activity in Vitro and in Cell Culture Models of Metachromatic Leukodystrophy*

A. Hasilik, G. Schwarzmann, K. Sandhoff, 2009, Journal of Biological Chemistry.

Development of an assay for the intermembrane transfer of cholesterol by Niemann-Pick C2 protein

M. Wendeler, K. Sandhoff, G. Schwarzmann, 2007, Biological chemistry.

Saposin B mobilizes lipids from cholesterol‐poor and bis(monoacylglycero)phosphate‐rich membranes at acidic pH

K. Sandhoff, G. Schwarzmann, Bernadette Breiden, 2007, The FEBS journal.

Optimization of submerged keratinocyte cultures for the synthesis of barrier ceramides.

K. Sandhoff, Bernadette Breiden, T. Doering, 2007, European journal of cell biology.

Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis.

S. Kaufmann, U. Schaible, S. Sad, 2006, Immunity.

TCF/Lef1-mediated control of lipid metabolism regulates skin barrier function.

W. Bloch, S. Brodesser, K. Sandhoff, 2012, The Journal of investigative dermatology.

Human Acid Ceramidase

F. Lang, T. Linke, E. Schuchman, 2001, The Journal of Biological Chemistry.

Normal epidermal differentiation but impaired skin-barrier formation upon keratinocyte-restricted IKK1 ablation

M. Pasparakis, W. Bloch, K. Sandhoff, 2007, Nature Cell Biology.

The epidermal barrier function is dependent on the serine protease CAP1/Prss8

K. Sandhoff, E. Hummler, M. Guitard, 2005, The Journal of cell biology.

Role for LAMP-2 in endosomal cholesterol transport

E. Ikonen, P. Saftig, S. Brodesser, 2009, Journal of cellular and molecular medicine.

Gangliosidoses | Encyclopedia

Bernadette Breiden, E. Klenk, 2020 .

Postnatal Requirement of the Epithelial Sodium Channel for Maintenance of Epidermal Barrier Function*

J. Stehle, Z. Haftek-Terreau, K. Sandhoff, 2008, Journal of Biological Chemistry.

Sphingolipid Storage Affects Autophagic Metabolism of the Amyloid Precursor Protein and Promotes Aβ Generation

P. Saftig, P. Mathews, J. Walter, 2011, The Journal of Neuroscience.

PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin

S. Ryser, S. Coughlin, J. Stehle, 2011, Nature communications.

Identification of a feedback loop involving β-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease

Anke Penno, P. Dörmann, Dagmar Wachten, 2017, The Journal of Biological Chemistry.

Physiological relevance of sphingolipid activator proteins in cultured human fibroblasts.

K. Sandhoff, G. Schwarzmann, Bernadette Breiden, 2003, Biochimie.

Membrane-spanning lipids for an uncompromised monitoring of membrane fusion and intermembrane lipid transfer

G. Schwarzmann, K. Sandhoff, Bernadette Breiden, 2015, Journal of Lipid Research.

Accumulation of Glucosylceramide in the Absence of the Beta-Glucosidase GBA2 Alters Cytoskeletal Dynamics

P. Dörmann, Dagmar Wachten, K. Sandhoff, 2015, PLoS genetics.

The role of sphingolipid metabolism in cutaneous permeability barrier formation.

K. Sandhoff, Bernadette Breiden, 2014, Biochimica et biophysica acta.

Lysosomal Glycosphingolipid Storage Diseases.

K. Sandhoff, Bernadette Breiden, 2019, Annual review of biochemistry.

Loss of keratin 10 is accompanied by increased sebocyte proliferation and differentiation.

J. Reichelt, K. Sandhoff, T. Magin, 2004, European journal of cell biology.

Ceramide Synthase Schlank Is a Transcriptional Regulator Adapting Gene Expression to Energy Requirements.

R. Bauer, J. Schultze, K. Klee, 2018, Cell reports.

Functional and genetic characterization of the non-lysosomal glucosylceramidase 2 as a modifier for Gaucher disease

M. Nöthen, S. Karlsson, M. Mattheisen, 2013, Orphanet Journal of Rare Diseases.

Schlank, a member of the ceramide synthase family controls growth and body fat in Drosophila

M. Hoch, U. Schepers, R. Bauer, 2009, The EMBO journal.

Inactivation of ceramide synthase 2 catalytic activity in mice affects transcription of genes involved in lipid metabolism and cell division.

J. Degen, K. Willecke, D. Hartmann, 2018, Biochimica et biophysica acta. Molecular and cell biology of lipids.