P. Mignatti

P. Dennis, R. Flaumenhaft, F. Blei, 1990, Cell differentiation and development : the official journal of the International Society of Developmental Biologists.

Thrombin cleaves the high molecular weight forms of basic fibroblast growth factor (FGF-2): a novel mechanism for the control of FGF-2 and thrombin activity

A. Galloway, P. Mignatti, G. Pintucci, 2008, Oncogene.

Inhibition of endothelial cell migration by gene transfer of tissue inhibitor of metalloproteinases-1.

A. Galloway, K. Kallenbach, P. Mignatti, 1999, The Journal of surgical research.

In vitro angiogenesis on the human amniotic membrane: requirement for basic fibroblast growth factor-induced proteinases

D. Rifkin, P. Mignatti, E. Robbins, 1989, The Journal of cell biology.

Human placental tissue stimulates bovine capillary endothelial cell growth, migration and protease production

M. Presta, D. Moscatelli, P. Mignatti, 1985, Bioscience reports.

Role of Degradative Enzymes in Wound Healing

D. Rifkin, P. Mignatti, H. Welgus, 1988 .

Expression of von Willebrand factor, an endothelial cell marker, is up‐regulated by angiogenesis factors: A potential method for objective assessment of tumor angiogenesis

L. Zanetta, H. Cohen, Kenneth Eng, 2000, International journal of cancer.

Soluble factor(s) released from neutrophils activates endothelial cell matrix metalloproteinase-2.

A. Galloway, S. Marcus, P. Mignatti, 1998, The Journal of surgical research.

Urokinase Plasminogen Activator and Gelatinases Are Associated with Membrane Vesicles Shed by Human HT1080 Fibrosarcoma Cells*

V. Dolo, H. Nagase, P. Mignatti, 1997, The Journal of Biological Chemistry.

Neutrophil-derived serine proteinases enhance membrane type-1 matrix metalloproteinase-dependent tumor cell invasion.

A. Galloway, S. Marcus, P. Mignatti, 2000, Surgery.

Tissue Inhibitor of Metalloproteinases-2 Binding to Membrane-type 1 Matrix Metalloproteinase Induces MAPK Activation and Cell Growth by a Non-proteolytic Mechanism*

A. Strongin, A. Galloway, D. Roses, 2008, Journal of Biological Chemistry.

Modulation of matrix metalloproteinase activity in human saphenous vein grafts using adenovirus-mediated gene transfer.

A. Galloway, A. Apazidis, K. Kallenbach, 1998, Surgery.

Trophic Effects of Platelets on Cultured Endothelial Cells are Mediated by Platelet-associated Fibroblast Growth Factor-2 (FGF-2) and Vascular Endothelial Growth Factor (VEGF)

S. Rafii, S. Froum, D. Green, 2002, Thrombosis and Haemostasis.

Control of type IV collagenase activity by components of the urokinase–plasmin system: a regulatory mechanism with cell‐bound reactants

L. Zanetta, S. Garbisa, P. Mignatti, 1997, The EMBO journal.

Modulation of Breast Cancer Cell Functions by Intracellular Signaling Through the Membrane Type-1 Matrix Metalloproteinase

P. Mignatti, 2002 .

Roles of MT1‐MMP in the Regulation of Cell Surface Proteolysis

S. Marcus, P. Mignatti, P. Shamamian, 1999, Annals of the New York Academy of Sciences.

The Nonproteolytic Intracellular Domain of Membrane-Type 1 Matrix Metalloproteinase Coordinately Modulates Abdominal Aortic Aneurysm and Atherosclerosis in Mice—Brief Report

M. Attur, B. Ramkhelawon, P. Mignatti, 2022, Arteriosclerosis, thrombosis, and vascular biology.

Anti‐proliferative and anti‐inflammatory effects of topical MAPK inhibition in arterialized vein grafts

A. Galloway, P. Mignatti, D. Kadian-Dodov, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The fibrinolytic system and angiogenesis

P. Mignatti, 1993 .

The role of proteases in matrix breakdown during cellular invasion.

D. Rifkin, P. Mignatti, R. Tsuboi, 1989, The American review of respiratory disease.

Transforming growth factor-beta1 induces apoptosis in vascular endothelial cells by activation of mitogen-activated protein kinase.

A. Galloway, P. Mignatti, E. Grossi, 2002, Surgery.

Extracellular matrix remodeling by metalloproteinases and plasminogen activators.

P. Mignatti, 1995, Kidney international. Supplement.

Purification and biological activities of an angiogenesis factor from human placenta.

D. Rifkin, M. Presta, D. Moscatelli, 1986, Anticancer research.

Plasmin activates pro‐matrix metalloproteinase‐2 with a membrane‐type 1 matrix metalloproteinase‐dependent mechanism

J. Keski‐Oja, K. Lehti, Jorma Keski-Oja, 2002, Journal of cellular physiology.

Plasminogen activators and matrix metalloproteinases in angiogenesis.

D. Rifkin, P. Mignatti, 1996, Enzyme & protein.

Transformation-enhancing factor(s) released from chicken Rous sarcoma cells: effect on some transformation parameters.

D. Lawrence, P. Vigier, P. Mignatti, 1981, Virology.

Tumor invasion through the human amniotic membrane: Requirement for a proteinase cascade

D. Rifkin, P. Mignatti, E. Robbins, 1986, Cell.

Nonenzymatic interactions between proteinases and the cell surface: novel roles in normal and malignant cell physiology.

D. Rifkin, P. Mignatti, 2000, Advances in cancer research.

Plasminogen activators, activation inhibitors and alpha2‐macroglobulin produced by cultured normal and malignant human cells

A. Vaheri, W. Schleuning, O. Saksela, 1984, International journal of cancer.

Enhancement of plasminogen activator activity by the culture medium of Rous sarcoma virus-transformed cells.

P. Mignatti, S. Barlati, 1982, The Journal of general virology.

Potential diagnostic and prognostic significance of the transformation‐enhancing factor(s) in the plasma cryoprecipitate of tumor patients

E. Ascari, P. Mignatti, S. Barlati, 1980, International journal of cancer.

Plasminogen activator activity of human plasma and transformed cells conditioned media: Dependence on divalent cations

M. Colombi, P. Mignatti, S. Barlati, 1987 .

Proteinases and Tissue Remodeling

D. Rifkin, W. Parks, P. Mignatti, 1988 .

Expression of viral oncogenes in differentiating chick embryo neuroretinal cells infected with avian tumor viruses.

G. Calothy, B. Pessac, G. Dambrine, 1980, Cold Spring Harbor symposia on quantitative biology.

Biology and biochemistry of proteinases in tumor invasion.

D. Rifkin, P. Mignatti, 1993, Physiological reviews.

Membrane-type 1 Matrix Metalloproteinase Modulates Tissue Homeostasis by a Non-proteolytic Mechanism

S. Abramson, S. Yakar, M. Attur, 2020, iScience.

Membrane-type 1 matrix metalloproteinase (MMP-14) modulates tissue homeostasis by a non-proteolytic mechanism

S. Abramson, S. Yakar, M. Attur, 2019, bioRxiv.

Lack of ERK activation and cell migration in FGF‐2‐deficient endothelial cells

A. Galloway, D. Moscatelli, C. Basilico, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Protein targets of inflammatory serine proteases and cardiovascular disease

Ram Sharony, A. Galloway, P. Mignatti, 2010, Journal of Inflammation.

Increased Membrane Type 1 Matrix Metalloproteinase Expression from Adenoma to Colon Cancer

R. Wieczorek, D. Eisenberg, J. Scholes, 2002, Diseases of the colon and rectum.

Differential modulation of cell phenotype by different molecular weight forms of basic fibroblast growth factor: possible intracellular signaling by the high molecular weight forms

D. Rifkin, A. Bikfalvi, N. Quarto, 1995, The Journal of cell biology.

Induction of stromelysin‐1 (MMP‐3) by fibroblast growth factor‐2 (FGF‐2) in FGF‐2−/− microvascular endothelial cells requires prolonged activation of extracellular signal‐regulated kinases‐1 and ‐2 (ERK‐1/2)

A. Galloway, D. Moscatelli, P. Mignatti, 2003, Journal of cellular biochemistry.

Basic fibroblast growth factor, a protein devoid of secretory signal sequence, is released by cells via a pathway independent of the endoplasmic reticulum‐Golgi complex

D. Rifkin, T. Morimoto, P. Mignatti, 1992, Journal of cellular physiology.

Transforming growth factor‐beta 1 (TGF‐β1) induces angiogenesis through vascular endothelial growth factor (VEGF)‐mediated apoptosis

Brandoch D. Cook, V. Terushkin, P. Mignatti, 2009, Journal of cellular physiology.

Transforming growth factor-beta 1 (tgf-&946;1) induces angiogenesis through vascular endothelial growth factor (vegf)-mediated apoptosis

Vitaly Terushkin, Brandoch D. Cook, V. Terushkin, 2008 .

Basic fibroblast growth factor released by single, isolated cells stimulates their migration in an autocrine manner.

D. Rifkin, T. Morimoto, P. Mignatti, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Activation of mitogen-activated protein kinases during preparation of vein grafts and modulation by a synthetic inhibitor.

A. Galloway, P. Mignatti, E. Grossi, 2003, The Journal of thoracic and cardiovascular surgery.

Monoclonal antibody to vascular endothelial-cadherin is a potent inhibitor of angiogenesis, tumor growth, and metastasis.

L. Zanetta, F. Liao, D. Hicklin, 2000, Cancer research.

VEGF, a prosurvival factor, acts in concert with TGF-β1 to induce endothelial cell apoptosis

A. Galloway, Aubrey C. Galloway, Kevin Hyman, 2006, Proceedings of the National Academy of Sciences.

Release of basic fibroblast growth factor, an angiogenic factor devoid of secretory signal sequence: A trivial phenomenon or a novel secretion mechanism?

D. Rifkin, P. Mignatti, 1991, Journal of cellular biochemistry.

Infantile Hemangioma Originates From A Dysregulated But Not Fully Transformed Multipotent Stem Cell

L. Chiriboga, P. Mignatti, Michael Gregory, 2016, Scientific Reports.

Vascular injury and modulation of MAPKs: a targeted approach to therapy of restenosis.

A. Galloway, P. Mignatti, G. Pintucci, 2007, Cellular signalling.

Basic fibroblast growth factor-induced activation of latent transforming growth factor beta in endothelial cells: regulation of plasminogen activator activity

D. Rifkin, R. Flaumenhaft, M. Abe, 1992, The Journal of cell biology.

Tumor cell‐conditioned medium stimulates expression of the urokinase receptor in vascular endothelial cells

S. Mandriota, P. Mignatti, G. Seghezzi, 1996, Journal of cellular physiology.

Plasminogen activators and angiogenesis.

D. Rifkin, P. Mignatti, 1996, Current topics in microbiology and immunology.

Vascular Endothelial Growth Factor Increases Urokinase Receptor Expression in Vascular Endothelial Cells (*)

S. Mandriota, J. Vassalli, N. Ferrara, 1995, The Journal of Biological Chemistry.

Matrix Metalloproteinase Inhibitors in Cancer Therapy: Turning Past Failures Into Future Successes

S. Adams, P. Mignatti, Arthur Winer, 2018, Molecular Cancer Therapeutics.

Membrane‐Type 1 Matrix Metalloproteinase Downregulates Fibroblast Growth Factor‐2 Binding to the Cell Surface and Intracellular Signaling

C. Valacca, P. Mignatti, E. Tassone, 2015, Journal of cellular physiology.

Shedding of Membrane Vesicles Mediates Fibroblast Growth Factor-2 Release from Cells*

P. Dell’Era, M. Presta, A. Pavan, 2003, Journal of Biological Chemistry.

Mechanical endothelial damage results in basic fibroblast growth factor-mediated activation of extracellular signal-regulated kinases.

A. Galloway, A. Apazidis, P. Mignatti, 1999, Surgery.

Mechanisms of c-reactive protein up-regulation in arterialized vein grafts.

A. Galloway, P. Mignatti, G. Pintucci, 2006, Surgery.

Correlation between plasma osteopontin levels and aortic valve calcification: potential insights into the pathogenesis of aortic valve calcification and stenosis.

H. Pass, A. Galloway, I. Kronzon, 2009, The Journal of thoracic and cardiovascular surgery.

Inhibition of Breast Cancer Metastasis by Presurgical Treatment with an Oral Matrix Metalloproteinase Inhibitor: A Preclinical Proof-of-Principle Study

S. Adams, Dariush Moussai, J. Zhong, 2016, Molecular Cancer Therapeutics.

Inhibition of smooth muscle cell migration and neointima formation in vein grafts by overexpression of matrix metalloproteinase-3.

A. Heim, M. Karck, A. Haverich, 2009, Journal of vascular surgery.

TIMP-2 Interaction with MT1-MMP Activates the AKT Pathway and Protects Tumor Cells from Apoptosis

C. Valacca, P. Mignatti, E. Tassone, 2015, PloS one.

Matrix metalloproteinase expression in vein grafts: role of inflammatory mediators and extracellular signal-regulated kinases-1 and -2.

A. Galloway, P. Mignatti, E. Grossi, 2006, American journal of physiology. Heart and circulatory physiology.

Elevated expression of periostin in human osteoarthritic cartilage and its potential role in matrix degradation via matrix metalloproteinase‐13

S. Abramson, Lauren Y. Statman, M. Attur, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Bovine leukemia virus inhibiting activity in fetal calf serum.

P. Mignatti, L. Pagani, M. Debiaggi, 1984, Microbiologica.

Transforming growth factor-beta1 induces apoptosis in vascular endothelial cells by activation of mitogen-activated protein kinase.

A. Galloway, P. Mignatti, E. Grossi, 2002, Surgery.

Topical mitogen-activated protein kinases inhibition reduces intimal hyperplasia in arterialized vein grafts.

A. Galloway, P. Mignatti, G. Pintucci, 2009, The Journal of surgical research.

Activation of tumor cell matrix metalloproteinase-2 by neutrophil proteinases requires expression of membrane-type 1 matrix metalloproteinase.

A. Galloway, S. Marcus, P. Mignatti, 1998, Surgery.

Periostin interaction with discoidin domain receptor-1 (DDR1) promotes cartilage degeneration

S. Abramson, M. Attur, P. Mignatti, 2020, PloS one.

Urokinase Plasminogen Activator and Gelatinases Are Associated with Membrane Vesicles Shed by Human HT 1080 Fibrosarcoma Cells *

V. Dolo, H. Nagase, P. Mignatti, 1997 .

PKCε activation promotes FGF-2 exocytosis and induces endothelial cell proliferation and sprouting.

S. Donnini, L. Morbidelli, M. Ziche, 2013, Journal of molecular and cellular cardiology.

A Quantitative In Vitro Model of Smooth Muscle Cell Migration Through the Arterial Wall Using the Human Amniotic Membrane

A. Galloway, K. Kallenbach, P. Mignatti, 2003, Arteriosclerosis, thrombosis, and vascular biology.

Vein graft arterialization causes differential activation of mitogen-activated protein kinases.

A. Galloway, P. Mignatti, E. Grossi, 2004, The Journal of thoracic and cardiovascular surgery.

Tumor cells secrete an Angiogenic factor that stimulates basic fibroblast growth factor and Urokinase expression in Vascular Endothelial cells

P. Quax, G. D. Valle, D. Rifkin, 1994, Journal of cellular physiology.

Irsogladine maleate inhibits angiogenesis in wild-type and plasminogen activator-deficient mice.

D. Rifkin, D. Roses, R. Shapiro, 1998, The Journal of surgical research.

Transformation enhancing factors in vitro and in vivo. Potential as cancer markers

M. Colombi, A. Brega, A. Adamoli, 1988 .

Transforming growth factor-beta 1 (TGF-beta1) induces angiogenesis through vascular endothelial growth factor (VEGF)-mediated apoptosis.

Brandoch D. Cook, V. Terushkin, P. Mignatti, 2009, Journal of cellular physiology.

Extracellular Vesicles Biology and its Emerging Role in Osteoarthritis and Related Arthritides

P. Mignatti, M. Attur, T. Han, 2019, Rheumatology: Current Research.

New Observations on the Intracellular Localization and Release of bFGF a

D. Rifkin, N. Quarto, D. Moscatelli, 1991, Annals of the New York Academy of Sciences.

Modulation of matrix metalloproteinase activity in human saphenous vein grafts using adenovirus-mediated gene transfer.

A. Galloway, A. Apazidis, B. Mehrara, 1998, Surgery.

Activation of mitogen-activated protein kinases during preparation of vein grafts and modulation by a synthetic inhibitor.

A. Galloway, P. Mignatti, E. Grossi, 2003, The Journal of thoracic and cardiovascular surgery.

Transforming growth factor-beta 1 (TGF-beta1) induces angiogenesis through vascular endothelial growth factor (VEGF)-mediated apoptosis.

Brandoch D. Cook, V. Terushkin, P. Mignatti, 2009, Journal of Cellular Physiology.

Urokinase Receptor Promotes Skin Tumor Formation by Preventing Epithelial Cell Activation of Notch1.

C. Brombin, A. Gandelli, F. Blasi, 2015, Cancer research.

Arrested Development: Infantile Hemangioma and the Stem Cell Teratogenic Hypothesis.

L. Chiriboga, P. Mignatti, Michael Gregory, 2017, Lymphatic research and biology.

Inhibition of rous sarcoma‐virus‐induced transformation by proteins involved in blood coagulation

A. Brega, P. Mignatti, S. Barlati, 1980, International journal of cancer.