A. Cordeiro

发表

Inhibition of Trypanosoma brucei glucose-6-phosphate dehydrogenase by human steroids and their effects on the viability of cultured parasites.

P. Michels, O. Thiemann, Paul A M Michels, 2009, Bioorganic & medicinal chemistry.

16-bromoepiandrosterone, an activator of the mammalian immune system, inhibits glucose 6-phosphate dehydrogenase from Trypanosoma cruzi and is toxic to these parasites grown in culture.

O. Thiemann, A. Cordeiro, 2010, Bioorganic & medicinal chemistry.

Glucose-6-phosphate dehydrogenase is the target for the trypanocidal action of human steroids.

P. Michels, A. Cordeiro, Shreedhara Gupta, 2011, Molecular and biochemical parasitology.

Discovery of New Uncompetitive Inhibitors of Glucose-6-Phosphate Dehydrogenase

A. Cordeiro, G. F. Mercaldi, A. T. Ranzani, 2014, Journal of biomolecular screening.

Biochemical characterization and inhibition of the alternative oxidase enzyme from the fungal phytopathogen Moniliophthora perniciosa

G. Pereira, A. Moore, A. Cordeiro, 2020, Communications Biology.

Synthesis and testing of novel alternative oxidase (AOX) inhibitors with antifungal activity against Moniliophthora perniciosa (Stahel), the causal agent of witches' broom disease of cocoa, and other phytopathogens.

M. Carazzolle, P. S. Oliveira, José G C Pereira, 2018, Pest management science.

Trypanosoma cruzi Malic Enzyme Is the Target for Sulfonamide Hits from the GSK Chagas Box.

A. Cordeiro, G. F. Mercaldi, A. T. Ranzani, 2021, ACS infectious diseases.

Cloning, expression, purification, and characterization of Leishmania major dihydroorotate dehydrogenase.

A. Costa-Filho, M. Nonato, A. Cordeiro, 2006, Protein expression and purification.

High-Throughput Screening Reveals New Glutaminase Inhibitor Molecules.

M. M. Dias, Rafael V. C. Guido, D. Adamoski, 2021, ACS pharmacology & translational science.

The structure of a Trypanosoma cruzi glucose‐6‐phosphate dehydrogenase reveals differences from the mammalian enzyme

A. Cordeiro, G. F. Mercaldi, A. Dawson, 2016, FEBS letters.

Discovery and structural characterization of chicoric acid as a SARS-CoV-2 nucleocapsid protein ligand and RNA binding disruptor

Helder Veras Ribeiro Filho, M. Bajgelman, R. E. Marques, 2022, Scientific Reports.

Discovery of antichagasic inhibitors by high-throughput screening with Trypanosoma cruzi glucokinase.

Ana Rodriguez, A. Cordeiro, G. F. Mercaldi, 2019, Bioorganic & medicinal chemistry letters.

Selenocysteine incorporation in Kinetoplastid: selenophosphate synthetase (SELD) from Leishmania major and Trypanosoma brucei.

O. Thiemann, A. Cordeiro, A. L. Braga, 2008, Molecular and biochemical parasitology.

Identification of Specific Inhibitors of Trypanosoma cruzi Malic Enzyme Isoforms by Target-Based HTS

S. Wilkinson, A. Cordeiro, A. T. Ranzani, 2017, SLAS discovery : advancing life sciences R & D.

NADPH producing enzymes as promising drug targets for Chagas Disease.

A. Cordeiro, 2019, Current medicinal chemistry.

In Vitro Image-Based Assay for Trypanosoma cruzi Intracellular Forms.

A. Cordeiro, Amanda G Eufrásio, 2020, Methods in molecular biology.

The crystal structure of Trypanosoma cruzi glucokinase reveals features determining oligomerization and anomer specificity of hexose-phosphorylating enzymes.

D. Vertommen, W. Versées, P. Michels, 2007, Journal of molecular biology.

Molecular and biochemical characterization of novel glucokinases from Trypanosoma cruzi and Leishmania spp.

P. Michels, A. Cáceres, J. Concepción, 2007, Molecular and biochemical parasitology.

Glucose-6-Phosphate Dehydrogenase of Trypanosomatids: Characterization, Target Validation, and Drug Discovery

M. Igoillo-Esteve, P. Michels, A. Cordeiro, 2011, Molecular biology international.

Molecular basis for diaryldiamine selectivity and competition with tRNA in a type 2 methionyl-tRNA synthetase from a Gram-negative bacterium

Maxuel O. Andrade, C. Benedetti, A. Cordeiro, 2021, The Journal of biological chemistry.

Crystallization and preliminary X-ray diffraction analysis of Leishmania major dihydroorotate dehydrogenase.

M. Nonato, A. Cordeiro, P. Feliciano, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

First Nonphosphorylated Inhibitors of Phosphoglucose Isomerase Identified by Chemical Library Screening

Ana Rodriguez, P. S. Oliveira, A. Cordeiro, 2018, SLAS discovery : advancing life sciences R & D.

Crystal structure of dihydroorotate dehydrogenase from Leishmania major.

M. P. Pinheiro, M. Nonato, A. Cordeiro, 2012, Biochimie.

The crystal structure of glucose-6-phosphate isomerase from Leishmania mexicana reveals novel active site features.

L. Delboni, P. Michels, O. Thiemann, 2004, European journal of biochemistry.

Identification of Compounds With Antiviral Activity Against SARS-CoV-2 in the MMV Pathogen Box Using a Phenotypic High-Throughput Screening Assay

Jacqueline Farinha Shimizu, J. H. Smetana, R. E. Marques, 2022, Frontiers in Virology.

Structural role of the active‐site metal in the conformation of Trypanosoma brucei phosphoglycerate mutase

P. Michels, O. Thiemann, A. Cordeiro, 2012, The FEBS journal.

Adenosine Kinase couples sensing of cellular potassium depletion to purine metabolism

M. Murakami, K. Franchini, A. Cordeiro, 2018, Scientific Reports.

Crystal structure of human phosphoglucose isomerase and analysis of the initial catalytic steps.

G. Oliva, O. Thiemann, R. Garratt, 2003, Biochimica et biophysica acta.

Mutations in the tetramer interface of human glucose‐6‐phosphate dehydrogenase reveals kinetic differences between oligomeric states

A. Cordeiro, A. T. Ranzani, 2017, FEBS letters.

Pyrrole-indolinone SU11652 targets the nucleoside diphosphate kinase from Leishmania parasites.

M. Murakami, L. Zanphorlin, A. Cordeiro, 2017, Biochemical and biophysical research communications.

Discovery of Potent N-Ethylurea Pyrazole Derivatives as Dual Inhibitors of Trypanosoma brucei and Trypanosoma cruzi.

Ana Rodriguez, J. Baell, V. Avery, 2019, ACS medicinal chemistry letters.

Discovery and structural characterization of chicoric acid as a SARS-CoV-2 nucleocapsid protein ligand and RNA binding disruptor

Jacqueline Farinha Shimizu, M. Bajgelman, R. E. Marques, 2022, Scientific Reports.

Adenosine Kinase couples sensing of cellular potassium depletion to purine metabolism

M. Murakami, K. Franchini, A. Cordeiro, 2018, Scientific Reports.

Didydroorotate dehydrogenase from Leishmania major

M. Nonato, A. Cordeiro, P. Feliciano, 2010 .