J. Fiandor

发表

New Compound Sets Identified from High Throughput Phenotypic Screening Against Three Kinetoplastid Parasites: An Open Resource

David H. Drewry, Gonzalo Colmenarejo, James R. Brown, 2015, Scientific Reports.

Identification and Characterization of Hundreds of Potent and Selective Inhibitors of Trypanosoma brucei Growth from a Kinase-Targeted Library Screening Campaign

Gonzalo Colmenarejo, William G. Devine, T. Geary, 2014, PLoS neglected tropical diseases.

Cyclin-dependent kinase 12, a novel drug target for visceral leishmaniasis

Michael D. Urbaniak, David W. Gray, G. Drewes, 2018, Nature.

A facile regioselective 1-O-deacylation of peracylated glycopyranoses

M. García-López, F. Heras, J. Fiandor, 1985 .

Antifungal sordarins. part 3: synthesis and structure-activity relationships of 2',3'-fused oxirane derivatives.

J. Cuevas, J. Ruiz, Julia Castro, 2002, Bioorganic & medicinal chemistry letters.

Identification and Optimization of a Series of 8-Hydroxy Naphthyridines with Potent In Vitro Antileishmanial Activity: Initial SAR and Assessment of In Vivo Activity

S. Norval, Frederick R. C. Simeons, L. Stojanovski, 2020, Journal of medicinal chemistry.

University of Dundee Identification and Optimization of a Series of 8-Hydroxy Naphthyridines with Potent In Vitro Antileishmanial Activity

S. Norval, Frederick R. C. Simeons, L. Stojanovski, 2020 .

Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma

A. Hill, Frederick R. C. Simeons, L. Stojanovski, 2017 .

Metabolic Clustering Analysis as a Strategy for Compound Selection in the Drug Discovery Pipeline for Leishmaniasis.

M. Barrett, C. Barbas, Emily G. Armitage, 2018, ACS chemical biology.

A Facile Regioselective 1-O-Deacylation of Peracylated Glycopyranoses.

M. García-López, F. Heras, J. Fiandor, 1986 .

Synthesis and Antiviral Activity of 5′-O-Sulfamoyluridine Derivatives

M. García-López, F. Heras, J. Fiandor, 1989 .

Discovery of pyrazolopyrrolidinones as potent, broad-spectrum inhibitors of Leishmania infection

S. Schaus, Ignacio Cotillo, J. McKerrow, 2023, Frontiers in Tropical Diseases.

Synthesis and structure-activity relationships of 4-pyridones as potential antimalarials.

James M. Woolven, E. Herreros, D. Gargallo‐Viola, 2008, Journal of medicinal chemistry.

Nucleosides: Potential Drugs for AIDS Therapy

M. Camarasa, F. Heras, J. Fiandor, 1990 .

Synthesis of 3′-deoxy-3′-(2-propynyl)thymidine and 3′-cyanomethyl-3′-deoxythymidine, analogs of AZT☆

S. Tam, J. Fiandor, 1990 .

Stereoselective synthesis of the antifungal GM222712

J. Fiandor, A. Fernández-Mayoralas, J. L. Chiara, 2000 .

Hexose-modified anti-viral analogues of uridine 5′-disphosphate glucose derivatives

Luis Carrasco, M. García-López, F. Heras, 1987 .

Scaffold-Hopping Strategy on a Series of Proteasome Inhibitors Led to a Preclinical Candidate for the Treatment of Visceral Leishmaniasis

Peter G. Dodd, Frederick R. C. Simeons, L. Stojanovski, 2021, Journal of medicinal chemistry.

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

Juan A. Bueren-Calabuig, David W. Gray, Frederick R. C. Simeons, 2019, Proceedings of the National Academy of Sciences.

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

David W. Gray, A. Hill, G. Drewes, 2018, Journal of medicinal chemistry.

Synthesis of 3′-C-Substituted-2′,3′-Dideoxynucleosldes as Potential Antcaids Agents

D. Huryn, S. Tam, J. Fiandor, 1989 .

Antifungal Sordarins. Part 4: synthesis and structure--activity relationships of 3',4'-fused alkyl-tetrahydrofuran derivatives.

S. Huss, J. Fiandor, F. Gómez de las Heras, 2002, Bioorganic & medicinal chemistry letters.

Antifungal Sordarins. Part 4. Synthesis and Structure—Activity Relationships of 3′,4′‐Fused Alkyl‐tetrahydrofuran Derivatives.

S. Huss, F. Heras, J. Fiandor, 2002 .

Antifungal sordarins. Synthesis and structure-activity relationships of 3',4'-fused dioxolane and dioxane derivatives.

J. Cuevas, J. Fiandor, F. Gómez de las Heras, 2002, Bioorganic & medicinal chemistry letters.

Antifungal Sordarins. Synthesis and Structure—Activity Relationships of 3′,4′-Fused Dioxolane and Dioxane Derivatives.

J. Cuevas, F. Heras, J. Fiandor, 2002 .

Stereocontrolled glycosylation of sordaricin in the presence of ammonium salts

J. Fiandor, A. Fernández-Mayoralas, J. L. Chiara, 2000 .

Selective benzoylation of 2-deoxy-D-arabino-hexose: synthesis of 3,6-di-O-benzoyl-2,4-dideoxy-D-threo-hexopyranose.

F. G. de las Heras, J. Fiandor, 1986, Carbohydrate research.

Synthesis of 5′-C-Chain-Extended Uridines by Reaction of 5′-Halonucleosides with Malonic Acid Type Derivatives

M. García-López, F. Heras, J. Fiandor, 1989 .

Exploration of 4(1H)-pyridones as a novel family of potent antimalarial inhibitors of the plasmodial cytochrome bc1.

F. Gamo, E. Herreros, Iñigo Angulo-Barturen, 2012, Future medicinal chemistry.

Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi

A. Hill, Frederick R. C. Simeons, L. Stojanovski, 2017, Journal of medicinal chemistry.

Identifying inhibitors of the Leishmania inositol phosphorylceramide synthase with antiprotozoal activity using a yeast-based assay and ultra-high throughput screening platform

E. Alvarez, Gonzalo Colmenarejo, J. G. Mina, 2018, Scientific Reports.

Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis

Michael D. Urbaniak, G. Drewes, Markus Boesche, 2018, Nature.

Falcipain inhibitors: optimization studies of the 2-pyrimidinecarbonitrile lead series.

Juan Miguel, Jiri Gut, Maria Marco, 2010, Journal of medicinal chemistry.

An Invitation to Open Innovation in Malaria Drug Discovery: 47 Quality Starting Points from the TCAMS.

José María Bueno, Esther Fernández, Simon J F Macdonald, 2011, ACS medicinal chemistry letters.

Synthesis and Structure-Activity Relationships of the Novel Antimalarials 5-Pyridinyl-4(1 H)-Pyridones.

J. Burrows, E. Herreros, Iñigo Angulo-Barturen, 2018, Journal of medicinal chemistry.

Potent antimalarial 4-pyridones with improved physico-chemical properties.

J. Vidal, J. Lavandera, E. Herreros, 2011, Bioorganic & medicinal chemistry letters.

Author Correction: Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis

Michael D. Urbaniak, David W. Gray, G. Drewes, 2023, Nature.

Identifying inhibitors of the Leishmania inositol phosphorylceramide synthase with antiprotozoal activity using a yeast-based assay and ultra-high throughput screening platform

E. Alvarez, Gonzalo Colmenarejo, P. Denny, 2018, Scientific Reports.

Identification of 6-amino-1H-pyrazolo[3,4-d]pyrimidines with in vivo efficacy against visceral leishmaniasis† †Electronic supplementary information (ESI) available. See DOI: 10.1039/d0md00203h

S. Norval, Frederick R. C. Simeons, L. Stojanovski, 2020, RSC medicinal chemistry.

Cyclin-dependent kinase 12, a novel drug target for visceral leishmaniasis

Michael D. Urbaniak, David W. Gray, G. Drewes, 2018, Nature.