Xiaoxia Gao

X. Qin, G. Du, Yuzhi Zhou, 2020, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Integrated Network Pharmacology and Metabolomics to Dissect the Combination Mechanisms of Bupleurum chinense DC-Paeonia lactiflora Pall Herb Pair for Treating Depression.

X. Qin, G. Du, Yuzhi Zhou, 2020, Journal of ethnopharmacology.

Chaigui granule exerts anti-depressant effects by regulating the synthesis of Estradiol and the downstream of CYP19A1-E2-ERKs signaling pathway in CUMS-induced depressed rats

Yao Gao, Teng Xu, X. Qin, 2022, Frontiers in Pharmacology.

Pharmacokinetics-pharmacodynamics and tissue distribution analysis of Low Polar extract of Xiaoyao Powder combined with rat model of chronic unpredictable mild stress

X. Qin, G. Du, Yuzhi Zhou, 2019, Journal of Liquid Chromatography & Related Technologies.

Synergistic neuroprotective effect of saikosaponin A and albiflorin on corticosterone-induced apoptosis in PC12 cells via regulation of metabolic disorders and neuroinflammation

Yuzhi Zhou, Yan-fei Wu, Xiaoxia Gao, 2022, Molecular Biology Reports.

Discovery of 1,3-diyne compounds as novel and potent antidepressant agents: synthesis, cell-based assay and behavioral studies

X. Qin, Jianbin Chao, Yuzhi Zhou, 2017 .

Neuroprotective and Cytotoxic Phthalides from Angelicae Sinensis Radix

X. Qin, G. Du, Yuzhi Zhou, 2016, Molecules.

Total syntheses of bupleurynol and its analog

Jianbin Chao, Xiaoxia Gao, Kaiqing Ma, 2017 .

Identification and quantification of the major volatile constituents in antidepressant active fraction of xiaoyaosan by gas chromatography-mass spectrometry.

Xuemei Qin, X. Qin, Yuzhi Zhou, 2012, Journal of ethnopharmacology.

Research on the Pathological Mechanism and Drug Treatment Mechanism of Depression

X. Qin, Yuzhi Zhou, Guo-jiang Peng, 2015, Current neuropharmacology.

Plasma-metabolite-biomarkers for the therapeutic response in depressed patients by the traditional Chinese medicine formula Xiaoyaosan: A (1)H NMR-based metabolomics approach.

X. Qin, G. Du, Yuzhi Zhou, 2015, Journal of affective disorders.

Anti‐depressant effects of Xiaoyaosan on rat model of chronic unpredictable mild stress: a plasma metabonomics study based on NMR spectroscopy

X. Qin, G. Du, Hai-feng Sun, 2012, The Journal of pharmacy and pharmacology.

Chemical profliling of Dingkun Dan by ultra High performance liquid chromatography Q exactive orbitrap high resolution mass spectrometry.

X. Qin, Xiaoxia Gao, J. Jia, 2020, Journal of pharmaceutical and biomedical analysis.

Dose-Effect/Toxicity of Bupleuri Radix on Chronic Unpredictable Mild Stress and Normal Rats Based on Liver Metabolomics

X. Qin, Xiaoxia Gao, Zhenyu Li, 2021, Frontiers in Pharmacology.

Deciphering the Differential Effective and Toxic Responses of Bupleuri Radix following the Induction of Chronic Unpredictable Mild Stress and in Healthy Rats Based on Serum Metabolic Profiles

X. Qin, Yuan Fang, Xiaoxia Gao, 2018, Front. Pharmacol..

Protective effect of isoliquiritin against corticosterone-induced neurotoxicity in PC12 cells.

X. Qin, Li Gao, G. Du, 2017, Food & function.

Study of plasma metabolic profiling and biomarkers of chronic unpredictable mild stress rats based on gas chromatography/mass spectrometry.

X. Qin, G. Du, Hai-feng Sun, 2010, Rapid communications in mass spectrometry : RCM.

Multi-omics reveals the mechanisms of antidepressant-like effects of the low polarity fraction of Bupleuri Radix.

X. Qin, Xiaoxia Gao, Yan Feng, 2020, Journal of ethnopharmacology.

Brain and testicular metabonomics revealed the protective effects of Guilingji on senile sexual dysfunction rats.

X. Qin, Xiaoxia Gao, Sijun Zhao, 2022, Journal of ethnopharmacology.

Antidepressant Response Metabonomics

X. Qin, Yuzhi Zhou, Xiaoxia Gao, 2014 .

Effects of Guilingji on Aging Rats and Its Underlying Mechanisms.

X. Qin, G. Du, Xiaoxia Gao, 2020, Rejuvenation research.

Plasma metabolomics of depressed patients and treatment with Xiaoyaosan based on mass spectrometry technique.

X. Qin, G. Du, Ke Li, 2020, Journal of ethnopharmacology.

Antidepressant-like effect of triterpenoids extracts from Poria cocos on the CUMS rats by 16S rRNA gene sequencing and LC–MS metabolomics

X. Qin, Xiaoxia Gao, Yan Feng, 2020 .

Antidepressant-like effects of the fractions of Xiaoyaosan on rat model of chronic unpredictable mild stress.

X. Qin, Yuzhi Zhou, Xiaoxia Gao, 2011, Journal of ethnopharmacology.

Metabonomic study on chronic unpredictable mild stress and intervention effects of Xiaoyaosan in rats using gas chromatography coupled with mass spectrometry.

Haifeng Sun, X. Qin, G. Du, 2011, Journal of ethnopharmacology.

Metabonomic Analysis of Urine from Chronic Unpredictable Mild Stress Rats Using Gas Chromatography–Mass Spectrometry

X. Qin, G. Du, Hai-feng Sun, 2012, Chromatographia.

Exploration of chemical composition and absorption characteristics of Chaigui granules based on UHPLC-Q-orbitrap-MS/MS.

X. Qin, Xiaoxia Gao, Peng-Wen Wang, 2020, Journal of pharmaceutical and biomedical analysis.

Forsythiaside prevents β-amyloid-induced hippocampal slice injury by upregulating 2-arachidonoylglycerol via cannabinoid receptor 1-dependent NF-κB pathway

Xiaoxia Gao, Liwei Zhang, Yan Yan, 2019, Neurochemistry International.

Study of the Neurotransmitter Changes Adjusted by Circadian Rhythm in Depression Based on Liver Transcriptomics and Correlation Analysis.

Yao Gao, X. Qin, Xiaoxia Gao, 2021, ACS chemical neuroscience.

Urinary metabonomic study using a CUMS rat model of depression

X. Qin, G. Du, Hai-feng Sun, 2012, Magnetic resonance in chemistry : MRC.

Studies on the potential link between antidepressant effect of Xiaoyao San and its pharmacological activity of hepatoprotection based on multi-platform metabolomics.

X. Qin, G. Du, Yuzhi Zhou, 2019, Journal of ethnopharmacology.

[An exploration in the action targets for antidepressant bioactive components of Xiaoyaosan based on network pharmacology].

Yao Gao, X. Qin, Li Gao, 2015, Yao xue xue bao = Acta pharmaceutica Sinica.

Selection and dynamic metabolic response of rat biomarkers by metabonomics and multivariate statistical analysis combined with GC–MS

X. Qin, G. Du, Xiaoqing Zhang, 2014, Pharmacology Biochemistry and Behavior.

Studies on the Changes of Pharmacokinetics Behaviors of Phytochemicals and the Influence on Endogenous Metabolites After the Combination of Radix Bupleuri and Radix Paeoniae Alba Based on Multi-Component Pharmacokinetics and Metabolomics

X. Qin, G. Du, Yuzhi Zhou, 2021, Frontiers in Pharmacology.

An Investigation of the Antidepressant Action of Xiaoyaosan in Rats Using Ultra performance Liquid Chromatography–Mass Spectrometry Combined with Metabonomics

X. Qin, G. Du, Y. Choi, 2013, Phytotherapy research : PTR.

Integrating serum pharmacochemistry and metabolomics to study the combination mechanisms of Bupleurum chinense DC and Paeonia lactiflora pall for treating depression.

Xuemei Qin, Yuzhi Zhou, Xiaoxia Gao, 2022, Journal of ethnopharmacology.

[Research progress of circadian rhythm].

X. Qin, G. Du, Xiaoxia Gao, 2021, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

Radix Paeoniae Alba attenuates Radix Bupleuri-induced hepatotoxicity by modulating gut microbiota to alleviate the inhibition of saikosaponins on glutathione synthetase

Xuemei Qin, Yuzhi Zhou, Xiaoxia Gao, 2023, Journal of pharmaceutical analysis.

A qualitative, and quantitative determination and pharmacokinetic study of four polyacetylenes from Radix Bupleuri by UPLC-PDA-MS.

X. Qin, G. Du, Yuan Fang, 2015, Journal of pharmaceutical and biomedical analysis.

Integrating UHPLC-MS/MS quantitative analysis and exogenous purine supplementation to elucidate the antidepressant mechanism of Chaigui granules by regulating purine metabolism

Xuemei Qin, Yuzhi Zhou, Xiaoxia Gao, 2023, Journal of pharmaceutical analysis.