Adam M. Lopez

发表

Ontogenic changes in lung cholesterol metabolism, lipid content, and histology in mice with Niemann-Pick type C disease.

A. Weinberg, S. Turley, Charina M Ramirez, 2014, Biochimica et biophysica acta.

Suppression of brain cholesterol synthesis in male Mecp2-deficient mice is age dependent and not accompanied by a concurrent change in the rate of fatty acid synthesis

J. Chuang, S. Turley, Adam M. Lopez, 2017, Brain Research.

Niemann-Pick C1-deficient mice lacking sterol O-acyltransferase 2 have less hepatic cholesterol entrapment and improved liver function.

Ryan D. Jones, J. Repa, S. Turley, 2018, American journal of physiology. Gastrointestinal and liver physiology.

Delineation of metabolic responses of Npc1−/−nih mice lacking the cholesterol-esterifying enzyme SOAT2 to acute treatment with 2-hydroxypropyl-β-cyclodextrin

J. Repa, S. Turley, Charina M Ramirez, 2020, Steroids.

Ontogenesis and Modulation of Intestinal Unesterified Cholesterol Sequestration in a Mouse Model of Niemann–Pick C1 Disease

Ryan D. Jones, J. Repa, S. Turley, 2019, Digestive Diseases and Sciences.

Impact of loss of SOAT2 function on disease progression in the lysosomal acid lipase-deficient mouse

J. Chuang, S. Turley, Adam M. Lopez, 2018, Steroids.

Quantitation of the rates of hepatic and intestinal cholesterol synthesis in lysosomal acid lipase‐deficient mice before and during treatment with ezetimibe

J. Chuang, S. Turley, Adam M. Lopez, 2017, Biochemical pharmacology.

PRD125, a Potent and Selective Inhibitor of Sterol O-Acyltransferase 2 Markedly Reduces Hepatic Cholesteryl Ester Accumulation and Improves Liver Function in Lysosomal Acid Lipase-Deficient Mice

L. Rudel, H. Tomoda, J. Chuang, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Impact of physiological levels of chenodeoxycholic acid supplementation on intestinal and hepatic bile acid and cholesterol metabolism in Cyp7a1-deficient mice

Ryan D. Jones, J. Repa, J. Chuang, 2015, Steroids.

Ezetimibe markedly attenuates hepatic cholesterol accumulation and improves liver function in the lysosomal acid lipase-deficient mouse, a model for cholesteryl ester storage disease.

J. Chuang, S. Turley, Adam M. Lopez, 2014, Biochemical and biophysical research communications.

Hepatic entrapment of esterified cholesterol drives continual expansion of whole body sterol pool in lysosomal acid lipase-deficient mice.

J. Repa, D. Burns, S. Turley, 2014, American journal of physiology. Gastrointestinal and liver physiology.

Sustained and selective suppression of intestinal cholesterol synthesis by Ro 48-8071, an inhibitor of 2,3-oxidosqualene:lanosterol cyclase, in the BALB/c mouse.

J. Repa, M. Valasek, J. Chuang, 2014, Biochemical pharmacology.

Identification of Correlative Shifts in Indices of Brain Cholesterol Metabolism in the C57BL6/Mecp2tm1.1Bird Mouse, a Model for Rett Syndrome.

D. Lütjohann, J. Chuang, S. Turley, 2018, Lipids.

Measurement of Rates of Cholesterol and Fatty Acid Synthesis In Vivo Using Tritiated Water.

J. Chuang, S. Turley, Adam M. Lopez, 2017, Methods in molecular biology.

Impact of the loss of caveolin-1 on lung mass and cholesterol metabolism in mice with and without the lysosomal cholesterol transporter, Niemann-Pick type C1.

P. Scherer, D. Mundy, J. Chuang, 2014, Biochimica et biophysica acta.

Paneth cell–derived growth factors support tumorigenesis in the small intestine

I. Dozmorov, E. Burstein, Jie Song, 2020, Life Science Alliance.

Liver and Biliary Tract Physiology/Pathophysiology Niemann-Pick C1-deﬁcient mice lacking sterol O -acyltransferase 2 have less hepatic cholesterol entrapment and improved liver function

Ryan D. Jones, J. Repa, S. Turley, 2018 .

Deletion of sterol O-acyltransferase 2 (SOAT2) function in mice deficient in lysosomal acid lipase (LAL) dramatically reduces esterified cholesterol sequestration in the small intestine and liver.

S. Turley, Adam M. Lopez, Kenneth S. Posey, 2014, Biochemical and biophysical research communications.

Systemic administration of 2‐hydroxypropyl‐β‐cyclodextrin to symptomatic Npc1‐deficient mice slows cholesterol sequestration in the major organs and improves liver function

Benny Liu, S. Turley, Charina M Ramirez, 2014, Clinical and experimental pharmacology & physiology.

Microbial Sensing by Intestinal Myeloid Cells Controls Carcinogenesis and Epithelial Differentiation

Haiying Li, E. Burstein, Wenhan Zhu, 2018, Cell reports.

NK cell defects in X-linked pigmentary reticulate disorder

N. Grishin, A. Zinn, L. Kinch, 2019, JCI insight.

Molecular markers of brain cholesterol homeostasis are unchanged despite a smaller brain mass in a mouse model of cholesteryl ester storage disease.

J. Repa, D. Burns, S. Turley, 2021, Lipids.

Endosomal PI(3)P regulation by the COMMD/CCDC22/CCDC93 (CCC) complex controls membrane protein recycling

L. Weisman, E. Burstein, Jie Song, 2019, Nature Communications.

Regulation of murine copper homeostasis by members of the COMMD protein family

B. van de Sluis, E. Burstein, Jie Song, 2020, Disease Models & Mechanisms.

An enteroendocrine-microbial axis in the large intestine controls host metabolism

J. Elmquist, J. McDonald, E. Burstein, 2023, Research square.