Jianxin Yu

发表

Apoptosis is induced by shikonin through the mitochondrial signaling pathway.

Xuxia Tang, Chen Zhang, J-C Wei, 2016, Molecular medicine reports.

Discovery of 6-(2-(dimethylamino)ethyl)-N-(5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole-6-yl)pyrimidin-2-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-amine as a highly potent cyclin-dependent kinase 4/6 inhibitor for treatment of cancer.

Q. Wang, Jianxin Yu, W. Xiao, 2019, European journal of medicinal chemistry.

Discovery of a novel series of imidazo[1',2':1,6]pyrido[2,3-d]pyrimidin derivatives as potent cyclin-dependent kinase 4/6 inhibitors.

Jianxin Yu, X. Liao, Guangxin Xia, 2020, European journal of medicinal chemistry.

Discovery and optimization of a series of imidazo[4,5-b]pyrazine derivatives as highly potent and exquisitely selective inhibitors of the mesenchymal-epithelial transition factor (c-Met) protein kinase.

Jianxin Yu, Jing Zhang, Guangxin Xia, 2016, Bioorganic & medicinal chemistry.

Gefitinib suppresses cervical cancer progression by inhibiting cell cycle progression and epithelial-mesenchymal transition.

Li Tang, Min Yang, Jianyun Zheng, 2019, Experimental and therapeutic medicine.

Potent and novel 11β-HSD1 inhibitors identified from shape and docking based virtual screening.

Bing Xiong, Jingkang Shen, Guangxin Xia, 2011, Bioorganic & medicinal chemistry letters.

Identification of 3-substituted-6-(1-(1H-[1,2,3]triazolo[4,5-b]pyrazin-1-yl)ethyl)quinoline derivatives as highly potent and selective mesenchymal-epithelial transition factor (c-Met) inhibitors via metabolite profiling-based structural optimization.

Jianxin Yu, Jing Zhang, Guangxin Xia, 2017, European journal of medicinal chemistry.

Discovery of 2-Alkyl-1-arylsulfonylprolinamides as 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors.

B. Xiong, Jing-kang Shen, Jianxin Yu, 2012, ACS medicinal chemistry letters.

Discovery of novel sulfonamides as potent and selective inhibitors against human and mouse 11β-hydroxysteroid dehydrogenase type 1

Mengzhu Xue, B. Xiong, Jing-kang Shen, 2012, Molecular and Cellular Endocrinology.