Shiyu Zhang

发表

Restricted HIV-1 Env glycan engagement by lectin-reengineered DAVEI protein chimera is sufficient for lytic inactivation of the virus.

I. Chaiken, C. Abrams, Amos B. Smith, 2018, The Biochemical journal.

Bifunctional Chimera That Coordinately Targets Human Immunodeficiency Virus 1 Envelope gp120 and the Host-Cell CCR5 Coreceptor at the Virus-Cell Interface.

M. Kutzler, I. Chaiken, Y. Long, 2018, Journal of medicinal chemistry.

Identification of a glycan cluster in gp120 essential for irreversible HIV-1 lytic inactivation by a lectin-based recombinantly engineered protein conjugate.

I. Chaiken, C. Abrams, B. Parajuli, 2020, The Biochemical journal.

Altered Env conformational dynamics as a mechanism of resistance to peptide-triazole HIV-1 inactivators

I. Chaiken, M. Root, Adel A Rashad, 2021, Retrovirology.

Peptide Triazole Thiol Irreversibly Inactivates Metastable HIV-1 Env by Accessing Conformational Triggers Intrinsic to Virus–Cell Entry

M. Kutzler, I. Chaiken, C. Abrams, 2021, Microorganisms.

Encapsulation of tricopper cluster in a protein-like cavitand enables facile redox processes from CuCuCu to CuCuCu states

Shiyu Zhang, C. Moore, Weiyao Zhang, 2020 .

Improved Durability to SARS-CoV-2 Vaccine Immunity following Coimmunization with Molecular Adjuvant Adenosine Deaminase-1

Emma A. Gordon, D. Weiner, M. Kutzler, 2022, The Journal of Immunology.

Molecular Adjuvant Adenosine Deaminase-1 Immunity following Coimmunization with Improved Durability to SARS-CoV-2 Vaccine

Emma A. Gordon, M. Kutzler, I. Chaiken, 2022 .

Controlling the Direction of S-Nitrosation versus Denitrosation: Reversible Cleavage and Formation of an S-N Bond within a Dicopper Center.

H. Shafaat, Shiyu Zhang, C. Moore, 2022, Journal of the American Chemical Society.

CXCL8 in Tumor Biology and Its Implications for Clinical Translation

Shiyu Zhang, L. Yang, S. Qiu, 2022, Frontiers in Molecular Biosciences.

DNA damage by reactive oxygen species resulting from metabolic activation of 8-epidiosbulbin E acetate in vitro and in vivo.

Shiyu Zhang, Jiang Zheng, Peng Luo, 2022, Toxicology and applied pharmacology.

Xanthone derivatives as phosphoglycerate mutase 1 inhibitors: Design, synthesis, and biological evaluation.

Deyong Ye, Shiyu Zhang, Yang Cao, 2018, Bioorganic & medicinal chemistry.

Discovery of 4-(1,2,4-Oxadiazol-5-yl)azepan-2-one Derivatives as a New Class of Cannabinoid Type 2 Receptor Agonists for the Treatment of Inflammatory Pain.

Yifei Wang, Mingli Xiang, Xin Yang, 2023, Journal of medicinal chemistry.

Discovery of Small Molecule Agonist of Gonadotropin-Releasing Hormone Receptor (GnRH1R)

Yifei Wang, Xin Yang, Yangli Zhou, 2022, J. Chem. Inf. Model..

A new generation Mpro inhibitor with potent activity against SARS-CoV-2 Omicron variants

Yifei Wang, H. Chu, J. Nan, 2023, Signal Transduction and Targeted Therapy.