P. Nara

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Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development

L K Pannell, L. Pannell, K. Gustafson, 1997, Antimicrobial agents and chemotherapy.

Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody.

D R Burton, R. M. Hendry, J. Pyati, 1994, Science.

Deceptive imprinting and immune refocusing in vaccine design.

L. Pena, M. Grubman, J. Long, 2008, Vaccine.

Refocusing neutralizing antibody response by targeted dampening of an immunological epitope

G. Rimmelzwaan, J. Goudsmit, A. Minassian, 2001 .

Identification of a new neutralizing epitope conformationally affected by the attachment of CD4 to gp120.

M. Posner, P. Nara, C. Kang, 1993, Journal of immunology.

Infl uenza A Pandemic ( H 1 N 1 ) 2009 Virus Infection in Domestic Cat

K. Harmon, K. Yoon, M. Killian, 2019 .

Influenza A Pandemic (H1N1) 2009 Virus Infection in Domestic Cat

K. Harmon, K. Yoon, M. Killian, 2010, Emerging infectious diseases.

Quantitative infectivity assay for HIV-1 and -2

P. Nara, P. Fischinger, 1988, Nature.

Blocking of human immunodeficiency virus infection depends on cell density and viral stock age

J. Spouge, M. Dembo, P. Nara, 1991, Journal of virology.

Inhibition of human immunodeficiency virus infectivity by chloroquine.

H. Kung, P. Nara, S. Oroszlan, 1990, AIDS research and human retroviruses.

Candidate HIV type 1 multideterminant cluster peptide-P18MN vaccine constructs elicit type 1 helper T cells, cytotoxic T cells, and neutralizing antibody, all using the same adjuvant immunization.

J. Berzofsky, M. Newman, C. D. Pendleton, 1996, AIDS research and human retroviruses.

Insertion of primary syncytium-inducing (SI) and non-SI envelope V3 loops in human immunodeficiency virus type 1 (HIV-1) LAI reduces neutralization sensitivity to autologous, but not heterologous, HIV-1 antibodies

J. Goudsmit, A. V. van Wijk, M. Bakker, 1995, Journal of virology.

Genomic diversity and antigenic variation of HIV‐1: links between pathogenesis, epidemiology and vaccine development

J. Goudsmit, P. Nara, N. Back, 1991, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cross-neutralizing antibodies to HIV-1 in mice after immunization with gp160 iscoms. Dissection of the immune response.

P. Nara, B. Morein, L. Åkerblom, 1991, AIDS research and human retroviruses.

Antibody-mediated in vitro neutralization of human immunodeficiency virus type 1 abolishes infectivity for chimpanzees

S. Matsushita, W. Schleif, E. Emini, 1990, Journal of virology.

Predominance of HIV-1 serotype distinct from LAV-1/HTLV-IIIB

J. Goudsmit, G. Zwart, P. Nara, 1990, The Lancet.

Cytokine-in-adjuvant steering of the immune response phenotype to HIV-1 vaccine constructs: granulocyte-macrophage colony-stimulating factor and TNF-alpha synergize with IL-12 to enhance induction of cytotoxic T lymphocytes.

J. Berzofsky, D. Alling, J. Ahlers, 1997, Journal of immunology.

Clonal patterns in the human immune response to HIV-1 infection.

G. Silverman, H. Wang, R. D’Amelio, 1992, International reviews of immunology.

Stimulation of HIV-1-neutralizing antibodies in simian HIV-IIIB-infected macaques.

W. Alvord, D. Margolin, S. Müller, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Serological characterization of guinea pigs infected with H3N2 human influenza or immunized with hemagglutinin protein

S. Schultz-Cherry, J. Long, P. Nara, 2010, Virology Journal.

Selective Pressure to Increase Charge in Immunodominant Epitopes of the H3 Hemagglutinin Influenza Protein

Michael W. Deem, M. Deem, Keyao Pan, 2010, Journal of Molecular Evolution.

A Novel Hypothesis for Original Antigenic Sin in the Severe Disease of SARS-CoV-2 Infection.

P. Nara, H. Kohler, 2020, Monoclonal antibodies in immunodiagnosis and immunotherapy.

Glycosylation affects both the three-dimensional structure and antibody binding properties of the HIV-1IIIB GP120 peptide RP135.

P. Roller, F. Lung, X. Huang, 1997, Biochemistry.

Topical application of Porphyromonas gingivalis into the gingival pocket in mice leads to chronic-active infection, periodontitis and systemic inflammation

N. Park, R. Kim, H. Ton-That, 2022, International journal of molecular medicine.

A group specific anamnestic immune reaction against HIV-1 induced by a candidate vaccine against AIDS

A. Burny, R. Cheynier, R. Gallo, 1988, Nature.

A cytopathic infectivity assay of human immunodeficiency virus type 1 in human primary macrophages.

J. Spouge, P. Nara, M. Merges, 1996, Journal of virological methods.

Porphyromonas gingivalis Outer Membrane Vesicles as the Major Driver of and Explanation for Neuropathogenesis, the Cholinergic Hypothesis, Iron Dyshomeostasis, and Salivary Lactoferrin in Alzheimer’s Disease

M. Penn, W. Griffin, J. Potempa, 2021, Journal of Alzheimer's disease : JAD.

CD4 antigen-based antireceptor peptides inhibit infectivity of human immunodeficiency virus in vitro at multiple stages of the viral life cycle.

K. M. Hwang, J. Lifson, L. Eiden, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Synthetic CD4 peptide derivatives that inhibit HIV infection and cytopathicity.

K. M. Hwang, J. Lifson, L. Eiden, 1988, Science.

Clonal dominance: cause for a limited and failing immune response to HIV-1 infection and vaccination.

J. Goudsmit, P. Nara, H. Kohler, 1992, Journal of acquired immune deficiency syndromes.

Guidelines for the Prevention of Simian Immunodeficiency Virus Infection in Laboratory Workers and Animal Handlers

R. Purcell, P. Jahrling, H. McClure, 1989, Journal of medical primatology.

The Biology of Human Immunodeficiency Virus‐1 IIIB Infection in the Chimpanzee: In Vivo and In Vitro Correlations

P. Nara, W. Hatch, J. Kessler, 1989, Journal of medical primatology.

Plant Proteins with Antiviral Activity Against Human Immunodeficiency Virus

S. Lee-Huang, Paul L Huang, H. Kung, 1992 .

Epitope Dampening Monotypic Measles Virus Hemagglutinin Glycoprotein Results in Resistance to Cocktail of Monoclonal Antibodies

F. Cosset, S. Russell, E. Verhoeyen, 2013, PloS one.

Immunohistochemical localization of human and simian immunodeficiency viral antigens in fixed tissue sections.

T. O'Leary, R. Rhodes, J. M. Ward, 1987, The American journal of pathology.

Partial purification of native HIV transmembrane protein gp41: generation of polyclonal and monoclonal antibodies.

L. Arthur, R. Gilden, S. Showalter, 1988, AIDS research and human retroviruses.

Genotypic and Phenotypic Variation of HIV-1: Impact on AIDS Pathogenesis and Vaccination (Part 1 of 2)

J. Goudsmit, P. Nara, T. Wolfs, 1993 .

Genotypic and phenotypic variation of HIV-1: impact on AIDS pathogenesis and vaccination.

J. Goudsmit, P. Nara, T. Wolfs, 1993, Chemical Immunology.

Challenge of chimpanzees (Pan troglodytes) immunized with human immunodeficiency virus envelope glycoprotein gp120

L. Arthur, J. Bess, R. Gallo, 1989, Journal of virology.

MAP 30: a new inhibitor of HIV‐1 infection and replication

S. Lee-Huang, Paul L Huang, H. Kung, 1990, FEBS letters.

Native but not denatured recombinant human immunodeficiency virus type 1 gp120 generates broad-spectrum neutralizing antibodies in baboons

K. Steimer, C. Scandella, N. Haigwood, 1992, Journal of virology.

The natural history of HIV-1 infection: virus load and virus phenotype independent determinants of clinical course?

D. van Strijp, H. Schuitemaker, G. Weverling, 1994, Virology.

Immune response to immunostimulatory complexes (ISCOMs) prepared from human immunodeficiency virus type 1 (HIV-1) or the HIV-1 external envelope glycoprotein (gp120).

L. Arthur, J. Bess, S. Pyle, 1989, Vaccine.

Targeted Alteration of Antibody-Based Immunodominance Enhances the Heterosubtypic Immunity of an Experimental PCV2 Vaccine

Gagandeep Singh, E. Leclerc, Oleksandr Kolyvushko, 2020, Vaccines.

Early antibody responses map to non-protective, PCV2 capsid protein epitopes.

P. Nara, S. Ramamoorthy, M. Ilha, 2019, Virology.

Rapid assessment of relationships among HIV isolates by oligopeptide analyses of external envelope glycoproteins.

M. Essex, P. Nara, M. Popovič, 1987, AIDS research and human retroviruses.

Immunization of chimpanzees confers protection against challenge with human immunodeficiency virus.

M. Kieny, P. Fultz, F. Barré-Sinoussi, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Neutralization of HIV‐1: a paradox of humoral proportions

J. Goudsmit, P. Nara, R. Garrity, 1991, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Loss of infectivity by progeny virus from alpha interferon-treated human immunodeficiency virus type 1-infected T cells is associated with defective assembly of envelope gp120

H. Gendelman, M. Meltzer, J. Bernbaum, 1992, Journal of virology.

LossofInfectivity byProgeny VirusfromAlphaInterferon- Treated HumanImmunodeficiency VirusType1-Infected T Cells IsAssociated withDefective Assembly ofEnvelope gpl20

H. Gendelman, M. Meltzer, J. Bernbaum, 1992 .

Anti-idiotype monoclonal antibody elicits broadly neutralizing anti-gp120 antibodies in monkeys.

H. Yoshiyama, D. Ho, W. Morrow, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Simple, rapid, quantitative, syncytium-forming microassay for the detection of human immunodeficiency virus neutralizing antibody.

M. Gonda, L. Arthur, P. Nara, 1987, AIDS research and human retroviruses.

Deceptive imprinting in the immune response against HIV-1.

S. Müller, P. Nara, H. Kohler, 1994, Immunology today.

Preliminary findings of an in vitro human spleen mononuclear cell culture system for primary isolates of HIV type 1.

H. Kung, J. Goudsmit, P. Nara, 1997, AIDS Research and Human Retroviruses.

The inability of human immunodeficiency virus to infect chimpanzee monocytes can be overcome by serial viral passage in vivo

H. Gendelman, M. Meltzer, B. Poiesz, 1991, Journal of virology.

Factors underlying spontaneous inactivation and susceptibility to neutralization of human immunodeficiency virus.

J. L. Raina, J. Spouge, J. Moore, 1992, Virology.

Antibody repertoire development in fetal and neonatal piglets XXI. Usage of most VH genes remains constant during fetal and postnatal development.

K. Chaloner, J. Urban, K. Lager, 2011, Molecular immunology.

Lipoprotein-associated oncornavirus-inactivating factor in the genus Mus: effects on murine leukemia viruses of laboratory and exotic mice.

P. Nara, N. Dunlop, P. Fischinger, 1987, Cancer research.

HIV requires multiple gp120 molecules for CD4-mediated infection

J. Spouge, M. Dembo, P. Nara, 1990, Nature.

Recombinant human Fab fragments neutralize human type 1 immunodeficiency virus in vitro.

C. Barbas, F. Chiodi, E. Norrby, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Two major groups of neutralizing anti-gp120 antibodies exist in HIV-infected individuals. Evidence for epitope diversity around the CD4 attachment site.

W. Morrow, H. Köhler, P. Nara, 1992, Journal of immunology.

Humoral Immunity to HIV-1:

P. Nara, 1996 .

Studies on murine lipoprotein associated oncornavirus inactivating factor : species distribution, developmental biology, mechanisms of viral inactivation, and identification of responsible proteins /

P. Nara, 1986 .

The presence and absence of histocompatibility antigens in HIV type 1 produced by autologous blood-derived macrophages and peripheral blood lymphoblasts.

H. Kung, P. Nara, W. Tsai, 1999, AIDS research and human retroviruses.

What role do periodontal pathogens play in osteoarthritis and periprosthetic joint infections of the knee?

J. Parvizi, G. Ehrlich, F. Hu, 2014, Journal of applied biomaterials & functional materials.

Perspectives on advancing preventative medicine through vaccinology at the comparative veterinary, human and conservation medicine interface: Not missing the opportunities

P. Nara, G. Tobin, G. Lin, 2008, Vaccine.

Vaccine-induced protection of chimpanzees against infection by a heterologous human immunodeficiency virus type 1

M. Kieny, P. Fultz, F. Barré-Sinoussi, 1995, Journal of virology.

Vaccine protection of chimpanzees against challenge with HIV-1-infected peripheral blood mononuclear cells.

M. Kieny, P. Fultz, F. Barré-Sinoussi, 1992, Science.

Human Immunodeficiency Virus (HIV)-Positive Sera Obtained Shortly after Seroconversion Neutralize Autologous HIV Type 1 Isolates on Primary Macrophages but Not on Lymphocytes

P. Nara, H. Rübsamen-Waigmann, U. Dietrich, 2000, Journal of Virology.

Evolution of human immunodeficiency virus type 1 envelope sequences in infected individuals with differing disease progression profiles.

G. Learn, A. Rodrigo, J. Mullins, 1998, Virology.

Deceptive imprinting: insights into mechanisms of immune evasion and vaccine development.

P. Nara, Peter L. Nara, 1999, Advances in veterinary medicine.

Deceptive imprinting: a cosmopolitan strategy for complicating vaccination.

P. Nara, R. Garrity, Peter L. Nara, 1998, Vaccine.

Immune strategies utilized by lentivirus infected chimpanzees to resist progression to AIDS.

J. Heeney, H. Niphuis, P. Nara, 1996, Immunology letters.

Effects of prednisolone on the development of immune responses to canine distemper virus in beagle pups.

S. Krakowka, P. Nara, T. Powers, 1979, American journal of veterinary research.

Experimental Streptococcus equi infection in the horse: correlation with in vivo and in vitro immune responses.

S. Krakowka, P. Nara, R. Garg, 1983, American journal of veterinary research.

HIV-specific immunity following immunization with HIV synthetic envelope peptides in asymptomatic HIV-infected patients.

S. Steinberg, J. Berzofsky, G. Shearer, 1999, AIDS.

Peptides Derived from the CDR3‐Homologous Domain of the CD4 Molecule Are Specific Inhibitors of HIV‐1 and SIV Infection, Virus‐Induced Cell Fusion, and Postinfection Viral Transmission in Vitro

K. M. Hwang, J. Lifson, M. McGrath, 1990, Annals of the New York Academy of Sciences.

Purified envelope glycoproteins from human immunodeficiency virus type 1 variants induce individual, type-specific neutralizing antibodies

L. Arthur, J. Bess, S. Pyle, 1988, Journal of virology.

Specific cellular immune response and neutralizing antibodies in goats immunized with native or recombinant envelope proteins derived from human T-lymphotropic virus type IIIB and in human immunodeficiency virus-infected men.

L. Arthur, R. Gallo, F. Wong-Staal, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Challenge of chimpanzees immunized with a recombinant canarypox-HIV-1 virus.

E. Paoletti, P. Fultz, F. Barré-Sinoussi, 1997, Virology.

Temporal analysis of the antibody response to HIV envelope protein in HIV-infected laboratory workers.

W. Blattner, M. Reitz, S. Pincus, 1994, The Journal of clinical investigation.

The role of the V3 loop of gp120 in HIV infection.

J. Moore, P. Nara, 1991, AIDS.

Antibody neutralization of retargeted measles viruses.

S. Russell, Takafumi Nakamura, P. Lech, 2014, Virology.

Short communication: no evidence of HTLV-3 and HTLV-4 infection in New York State subjects at risk for retroviral infection.

F. Siegal, C. Welch, Anish Thomas, 2010, AIDS research and human retroviruses.

Differential role of V3-specific antibodies in neutralization assays involving primary and laboratory-adapted isolates of HIV type 1.

D. Birx, N. Michael, V. Polonis, 1995, AIDS research and human retroviruses.

The Status and Role of Vaccines in the U.S. Food Animal Industry: Implications for Biological Terrorism

P. Nara, 1999, Annals of the New York Academy of Sciences.

Quantitative Assays for Virus Infectivity

Roy E. Byington, Victoria A. Johnson, V. Johnson, 1990 .

Qualitative and quantitative detection of HIV‐1 RNA by nucleic acid sequence‐based amplification

T. Kievits, J. Goudsmit, S. Jurriaans, 1993, AIDS.

Persistent infection of chimpanzees with human immunodeficiency virus: serological responses and properties of reisolated viruses

L. Arthur, D. Gajdusek, D. Asher, 1987, Journal of virology.

Stimulation of Antiviral Antibody Response in SHIV‐IIIB‐Infected Macaques

M. Axthelm, D. Margolin, P. Nara, 2001, Scandinavian journal of immunology.

Analysis of the cross-reactive anti-gp120 antibody population in human immunodeficiency virus-infected asymptomatic individuals

N. Haigwood, P. Nara, C. Kang, 1993, Journal of virology.

How Can Vaccines Against Influenza and Other Viral Diseases Be Made More Effective?

N. Wingreen, S. Levin, W. Ndifon, 2010, PLoS biology.

Preliminary in vitro growth cycle and transmission studies of HIV-1 in an autologous primary cell assay of blood-derived macrophages and peripheral blood mononuclear cells.

H. Kung, P. Nara, P L Nara, 1996, Virology.

Systemic and local intestinal antibody response in dogs given both infective and inactivated canine parvovirus.

S. Krakowka, P. Nara, R. Olsen, 1983, American journal of veterinary research.

Construction of an HIV-1 peptide vaccine containing a multideterminant helper peptide linked to a V3 loop peptide 18 inducing strong neutralizing antibody responses in mice of multiple MHC haplotypes after two immunizations.

J. Berzofsky, A. Minassian, C. D. Pendleton, 1993, Journal of immunology.

Epitopes recognized by the neutralizing antibodies of an HIV-1-infected individual.

L. Eckler, A. Profy, P. Nara, 1990, Journal of immunology.

Emergence of viruses resistant to neutralization by V3-specific antibodies in experimental human immunodeficiency virus type 1 IIIB infection of chimpanzees

R. Gallo, J. Goudsmit, P. Nara, 1990, Journal of virology.

In vitro evolution of a neutralizing human antibody to human immunodeficiency virus type 1 to enhance affinity and broaden strain cross-reactivity.

D R Burton, R. M. Hendry, C. Barbas, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Mutations in human immunodeficiency virus type 1 gp41 affect sensitivity to neutralization by gp120 antibodies

J. Goudsmit, M. Schutten, M Schutten, 1993, Journal of virology.

Mutations inHumanImmunodeficiency VirusType1gp4l Affect Sensitivity toNeutralization bygpl20Antibodies

P. Nara, T. Nicolek, 1993 .

Immunization with a soluble CD4-gp120 complex preferentially induces neutralizing anti-human immunodeficiency virus type 1 antibodies directed to conformation-dependent epitopes of gp120

J. Sodroski, J. Moore, P. Nara, 1994, Journal of virology.

Evolution of H3N2 Influenza Virus in a Guinea Pig Model

M. Deem, Keyao Pan, J. Long, 2011, PloS one.

Human plasma enhances the infectivity of primary human immunodeficiency virus type 1 isolates in peripheral blood mononuclear cells and monocyte-derived macrophages

J. Spouge, P. Nara, W. Tsai, 1995, Journal of virology.

gpl20 Generates Broad-Spectrum Neutralizing Antibodies in Baboons

C. Scandella, N. Haigwood, G. Ott, 2003 .

Decrease in cytokine production by HIV-infected macrophages in response to LPS-mediated activation.

K. Matsushima, H. Kung, P. Nara, 1991, Lymphokine and cytokine research.

Serological responses in chimpanzees inoculated with human immunodeficiency virus glycoprotein (gp120) subunit vaccine.

M. Gonda, L. Arthur, J. Bess, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Increase of Primary HIV‐1 Production in Human Peripheral Blood Mononuclear Cells by Intermittent Medium Replenishment

J. Spouge, Suh-Chin Wu, P. Nara, 1998, Biotechnology progress.

Priming with T helper cell epitope peptides enhances the antibody response to the envelope glycoprotein of HIV-1 in primates.

K. Cease, R. Desrosiers, M. Zweig, 1991, Journal of immunology.

Use of Old World Monkeys for Acquired Immunodeficiency Syndrome Research

R. Gallo, P. Nara, D. Zagury, 1989, Journal of medical primatology.

Analysis of B cell repertoire specific to the neutralizing epitopes of glycoprotein 120 in HIV-infected individuals.

J. McCutchan, P. Nara, C. Kang, 1994, AIDS research and human retroviruses.

Soluble CD4-gpl20 Complex Preferentially Induces Neutralizing Anti-Human Immunodeficiency Virus

J. Sodroski, John P. Moore, P. Nara, 2022 .

Evidence for non-V3-specific neutralizing antibodies that interfere with gp120/CD4 binding in human immunodeficiency virus 1-infected humans.

N. Haigwood, H. Köhler, P. Nara, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Few clues for AIDS vaccines from structural data on gp120 and its receptors and antibodies.

M. Schiffer, P. Nara, H. Kohler, 1999, Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association.

Persistent HIV-2 infection of rhesus macaque, baboon, and mangabeys.

P. Dubouch, P. Nara, J. Bernard, 1989, Intervirology.

Absence of cytotoxic antibody to human immunodeficiency virus-infected cells in humans and its induction in animals after infection or immunization with purified envelope glycoprotein gp120.

M. Gonda, P. Nara, P. Fischinger, 1987, Proceedings of the National Academy of Sciences of the United States of America.

HIV-1: the confounding variables of virus neutralization.

P. Nara, George Lin, Peter L Nara, 2005, Current drug targets. Infectious disorders.

Universal cellular tropism?

H. Kung, J. Goudsmit, P. Nara, 1992, Nature.

HIV-1 tropism: truth or consequences?

H. Kung, J. Goudsmit, P. Nara, 1992, AIDS research and human retroviruses.

Multicenter evaluation of quantification methods for plasma human immunodeficiency virus type 1 RNA.

M. Winters, S. Kwok, P. Reichelderfer, 1994, The Journal of infectious diseases.

Simultaneous isolation of simian foamy virus and HTLV-III/LAV from chimpanzee lymphocytes following HTLV-III or LAV inoculation

M. Gonda, L. Arthur, D. Gajdusek, 2005, Archives of Virology.

Immunohistochemical localization of human and simian immunodeficiency viral antigens in fixed tissue sections.

T. O'Leary, R. Rhodes, J. M. Ward, 1987, The American journal of pathology.

Refocusing neutralizing antibody response by targeted dampening of an immunodominant epitope.

P. Nara, G. Lin, G. Rimmelzwaan, 1997, Journal of immunology.

Evidence for rapid selection and deletion of HIV-1 subpopulations in vivo by V3-specific neutralizing antibody: a model of humoral-associated selection.

J. Goudsmit, P. Nara, L. Smit, 1990, Developments in biological standardization.

Preliminaryin VitroGrowth Cycle and Transmission Studies of HIV-1 in an Autologous Primary Cell Assay of Blood-Derived Macrophages and Peripheral Blood Mononuclear Cells

P. Nara, Hsiang-Fu Kung, Wen-Po Tsai, 1996 .