T. Zimmermann

发表

Loss of organic cation transporter 3 (Oct3) leads to enhanced proliferation and hepatocarcinogenesis

D. Schuppan, P. Galle, Jan Baumgart, 2017, Oncotarget.

Cloning and characterization of the promoter of Hugl-2, the human homologue of Drosophila lethal giant larvae (lgl) polarity gene.

P. Galle, S. Strand, G. Otto, 2008, Biochemical and biophysical research communications.

Selection and use of immunosuppressive therapies after liver transplantation: current German practice

F. Lehner, C. Strassburg, M. Guba, 2016, Clinical transplantation.

Efficacy and safety of a conversion from the original tacrolimus and mycophenolate mofetil to the generics Tacpan® and Mowel® after liver transplantation

P. Galle, H. Lang, J. Vollmar, 2015, Drug design, development and therapy.

Efficacy and safety of direct-acting antiviral therapy in previous hard-to-treat patients with recurrent hepatitis C virus infection after liver transplantation: a real-world cohort

P. Galle, H. Lang, D. Grimm, 2017, Drug design, development and therapy.

Early virological response may predict treatment response in sofosbuvir-based combination therapy of chronic hepatitis c in a multi-center “real-life” cohort

P. Galle, W. Stremmel, J. Schattenberg, 2015, BMC Gastroenterology.

Alterations in lipid, carbohydrate and iron metabolism in patients with non-alcoholic steatohepatitis (NASH) and metabolic syndrome.

P. Galle, H. Rossmann, J. Schattenberg, 2011, European journal of internal medicine.

Alterations in Lipid and Carbohydrate Metabolism in Patients with Classic Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency

K. Lackner, H. Rossmann, Matthias M. Weber, 2010, Hormone Research in Paediatrics.

Changes in lipid and carbohydrate metabolism under mTOR- and calcineurin-based immunosuppressive regimen in adult patients after liver transplantation.

P. Galle, H. Lang, T. Zimmermann, 2016, European journal of internal medicine.

[Detection of hepatic micrometastases in the context of adjuvant chemotherapy and surgery for hepatic metastases].

D. Jäger, M. Berger, H. Lang, 2010, Deutsche medizinische Wochenschrift.

Effects of Smoking on Pegylated Interferon alpha 2a and First Generation Protease Inhibitor-based Antiviral Therapy in Naïve Patients Infected with Hepatitis C Virus Genotype 1.

P. Galle, S. Mauss, P. Buggisch, 2016, Journal of gastrointestinal and liver diseases : JGLD.

Impact of pancreatic comorbidities in patients with end-stage liver disease on outcome after liver transplantation.

P. Galle, H. Lang, D. Grimm, 2014, European journal of internal medicine.

MRI Findings and Genotype Analysis in Patients with Childhood Onset Growth Hormone Deficiency- Correlation with Severity of Hypopituitarism

R. Pfäffle, M. Bettendorf, T. Zimmermann, 2007, Journal of pediatric endocrinology & metabolism : JPEM.

Liver Transplantation for Hepatocellular Carcinoma – Is There a Risk of Recurrence Caused by Intraoperative Blood Salvage Autotransfusion?

G. Otto, M. Kaths, A. Lautem, 2011, European Surgical Research.

No beneficial effect of all-trans retinoic acid in previous non-responder patients with chronic hepatitis C: the ATRACTION study, a phase II randomised trial.

C. Trautwein, T. Berg, P. Galle, 2013, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Downregulation of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) in human hepatocellular carcinoma and their prognostic significance

P. Galle, G. Otto, J. Schattenberg, 2012, BMC Cancer.

Predictive Factors for Sustained Virological Response after Treatment with Pegylated Interferon α-2a and Ribavirin in Patients Infected with HCV Genotypes 2 and 3

A. Schober, C. Niederau, S. Mauss, 2014, PloS one.

Direct‐acting antiviral treatment of chronic HCV‐infected patients on opioid substitution therapy: Still a concern in clinical practice?

S. Mauss, H. Wedemeyer, K. Böker, 2018, Addiction.

Real‐world experience with the all‐oral, interferon‐free regimen of ombitasvir/paritaprevir/ritonavir and dasabuvir for the treatment of chronic hepatitis C virus infection in the German Hepatitis C Registry

T. Berg, C. Sarrazin, S. Mauss, 2017, Journal of viral hepatitis.

Early changes in dynamic biomarkers of liver fibrosis in hepatitis C virus-infected patients treated with sofosbuvir.

D. Schuppan, P. Galle, J. Schattenberg, 2016, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Real-world effectiveness of 8-week treatment with ledipasvir/sofosbuvir in chronic hepatitis C.

C. Niederau, S. Zeuzem, S. Mauss, 2017, Journal of hepatology.

S3-Leitlinie „Prophylaxe, Diagnostik und Therapie der Hepatitis-C-Virus (HCV) -Infektion“

T. Berg, T. Zimmermann, S. Wirth, 2018, Zeitschrift für Gastroenterologie.

Combination therapy with silibinin, pegylated interferon and ribavirin in a patient with hepatitis C virus genotype 3 reinfection after liver transplantation: a case report

P. Galle, M. Wörns, T. Zimmermann, 2014, Journal of Medical Case Reports.

Cirrhosis risk score of the donor organ predicts early fibrosis progression after liver transplantation.

D. Schuppan, P. Galle, H. Lang, 2019, Journal of gastrointestinal and liver diseases : JGLD.

Lower Prevalence of the OCT2 Ser270 Allele in Patients with Essential Hypertension

A. Kastrati, A. Schömig, D. Gründemann, 2006, Clinical and experimental hypertension.

Ablation of c-FLIP in hepatocytes enhances death-receptor mediated apoptosis and toxic liver injury in vivo.

P. Galle, You-Wen He, J. Schattenberg, 2011, Journal of hepatology.

Managing hepatitis C in liver transplant patients with recurrent infection

G. Otto, M. Schuchmann, T. Zimmermann, 2009 .

Urinary ethyl glucuronide (uEtG) as a marker for alcohol consumption in liver transplant candidates: a real-world cohort

P. Galle, K. Lackner, J. Marquardt, 2020, Zeitschrift für Gastroenterologie.

Preoperative left ventricular hypertrophy is associated with reduced patient survival after liver transplantation

G. Otto, D. Grimm, T. Zimmermann, 2013, Clinical transplantation.

Interferon- and ribavirin-free therapy with new direct acting antivirals (DAA) for chronic hepatitis C improves vascular endothelial function.

P. Galle, T. Münzel, A. Grambihler, 2018, International journal of cardiology.

The recipient CYP2D6 allele 4‐associated poor metabolizer status correlates with an early fibrosis development after liver transplantation

P. Galle, I. Schmidtmann, G. Otto, 2011, Transplant international : official journal of the European Society for Organ Transplantation.

Pilot Study on Malnutrition and DNA Damage in Patients with Newly Diagnosed Gastrointestinal Tumors: Is DNA Damage Reversible by Early Individualized Nutritional Support?

P. Galle, H. Rossmann, B. Kaina, 2020, Journal of gastrointestinal and liver diseases : JGLD.

Diabetic liver injury from streptozotocin is regulated through the caspase-8 homolog cFLIP involving activation of JNK2 and intrahepatic immunocompetent cells

P. Galle, J. Schattenberg, T. Kohl, 2013, Cell Death and Disease.

The role of death effector domain-containing proteins in acute oxidative cell injury in hepatocytes.

P. Galle, You-Wen He, J. Schattenberg, 2012, Free radical biology & medicine.

Pretransplant coronary artery disease is a predictor for myocardial infarction and cardiac death after liver transplantation.

P. Galle, G. Otto, H. Lang, 2017, European journal of internal medicine.

Posttransplant Lymphoproliferative Disease in Liver Transplant Patients

M. Schuchmann, T. Zimmermann, C. Hartmann, 2011, Current infectious disease reports.

Prevention and Management of CMV Infections after Liver Transplantation: Current Practice in German Transplant Centers

F. Tacke, H. Schlitt, K. Weiss, 2020, Journal of clinical medicine.

Validation of the simplified Animal Naming Test as primary screening tool for the diagnosis of covert hepatic encephalopathy.

P. Galle, J. Schattenberg, C. Labenz, 2019, European journal of internal medicine.

Dynamics of liver stiffness by transient elastography in patients with chronic hepatitis C virus infection receiving direct‐acting antiviral therapy—Results from the German Hepatitis C‐Registry

M. Friedrich-Rust, S. Mauss, A. Geier, 2020, Journal of viral hepatitis.

285 DOWNREGULATION OF ORGANIC CATION TRANSPORTERS OCT1 (SLC22A1) AND OCT3 (SLC22A3) IN HUMAN HEPATOCELLULAR CARCINOMA AND THEIR PROGNOSTIC SIGNIFICANCE

P. Galle, G. Otto, M. Schuchmann, 2012 .

Activation of the extraneuronal monoamine transporter (EMT) from rat expressed in 293 cells

D. Gründemann, E. Schömig, T. Zimmermann, 2002, British journal of pharmacology.

New onset of diabetes after transplantation is associated with improved patient survival after liver transplantation due to confounding factor.

P. Galle, J. Schattenberg, H. Lang, 2015, European journal of internal medicine.

Acute organ failure following the loss of anti-apoptotic cellular FLICE-inhibitory protein involves activation of innate immune receptors

J. Schattenberg, I. Bergheim, J. Menke, 2014, Cell Death and Differentiation.

Cetuximab-induced skin exanthema: Improvement by a reactive skin therapy.

P. Galle, T. Zimmermann, M. Moehler, 2010, Molecular medicine reports.

Increased hepatic fibrosis and JNK2-dependent liver injury in mice exhibiting hepatocyte-specific deletion of cFLIP.

D. Schuppan, P. Galle, You-Wen He, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Tacrolimus effects and side effects after liver transplantation: is there a difference between immediate and extended release?

G. Otto, T. Zimmermann, M. Heise, 2013, Transplantation proceedings.

Hepatitis E virus genotype 3 is a common finding in liver‐transplanted patients undergoing liver biopsy for elevated liver enzymes with a low De Ritis ratio and suspected acute rejection: A real‐world cohort

P. Galle, J. Wenzel, H. Lang, 2018, Clinical transplantation.

Hepatitis E Is a Rare Finding in Liver Transplant Patients With Chronic Elevated Liver Enzymes and Biopsy-Proven Acute Rejection.

P. Galle, G. Otto, H. Lang, 2020, Transplantation proceedings.

Liver transplanted patients with preoperative autoimmune hepatitis and immunological disorders are at increased risk for Post-Transplant Lymphoproliferative Disease (PTLD).

P. Galle, G. Otto, J. Schattenberg, 2010, European journal of internal medicine.

Clinical significance of detectable and quantifiable HCV RNA at the end of treatment with ledipasvir/sofosbuvir in GT1 patients

M. Manns, C. Sarrazin, S. Mauss, 2018, Liver international : official journal of the International Association for the Study of the Liver.

[Prophylaxis, diagnosis and therapy of hepatitis-C-virus (HCV) infection: the German guidelines on the management of HCV infection - AWMF-Register-No.: 021/012].

P. Schirmacher, T. Berg, U. Spengler, 2018, Zeitschrift fur Gastroenterologie.

Early Steroid-Free Immunosuppression With FK506 After Liver Transplantation: Long-Term Results of a Prospectively Randomized Double-Blinded Trial

G. Otto, T. Zimmermann, N. Weiler, 2010, Transplantation.

Dynamic changes of lipid profile in Romanian patients with Gaucher disease type 1 under enzyme replacement therapy: a prospective study

D. Leucuta, K. Lackner, H. Rossmann, 2013, Journal of Inherited Metabolic Disease.

Prophylaxe, Diagnostik und Therapie der Hepatitis-C-Virus(HCV)-Infektion

T. Berg, S. Zeuzem, H. Wedemeyer, 2020, Zeitschrift für Gastroenterologie.

Telaprevir drug monitoring during antiviral therapy of hepatitis C graft infection after liver transplantation

P. Galle, N. Ferreirós, W. Bechstein, 2015, Liver international : official journal of the International Association for the Study of the Liver.

Risk factors in patients with rapid recurrent hepatitis C virus-related cirrhosis within 1 year after liver transplantation.

P. Galle, G. Otto, M. Schuchmann, 2009, Transplantation proceedings.

Efficacy of an escalating dose regimen of pegylated interferon α‐2a plus ribavirin in the early phase of HCV reinfection after liver transplantation

P. Galle, G. Otto, A. Lohse, 2007, Transplant international : official journal of the European Society for Organ Transplantation.

Defer or treat? Reasons for treatment decisions in patients with chronic hepatitis C genotype 1 in the early era of directly acting antiviral agents.

A. Grambihler, S. Koch, N. Weiss, 2014, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

K-ras mutation status correlates with the expression of VEGFR1, VEGFR2, and PDGFRα in colorectal cancer

P. Galle, I. Schmidtmann, M. Berger, 2010, International Journal of Colorectal Disease.

Low expression of chemokine receptor CCR5 in human colorectal cancer correlates with lymphatic dissemination and reduced CD8+ T-cell infiltration

M. Berger, H. Lang, I. Gockel, 2010, International Journal of Colorectal Disease.

Genetic variability of the extraneuronal monoamine transporter EMT (SLC22A3)

D. Gründemann, E. Schömig, A. Lazar, 2003, Journal of Human Genetics.

Exercise-induced increases in cell free DNA in human plasma originate predominantly from cells of the haematopoietic lineage.

M. Giacca, P. Simon, T. Zimmermann, 2015, Exercise immunology review.

SDF 1 β Expression in Renal Cell Carcinoma Correlates with Grading and Infiltration by CD 8 + T-Cells

P. Galle, W. Brenner, J. Thüroff, 2011 .

Surgical Duct-to-Duct Reconstruction: an Alternative Approach to Late Biliary Anastomotic Stricture After Deceased Donor Liver Transplantation

R. Kloeckner, H. Lang, K. Chavin, 2020, Journal of Gastrointestinal Surgery.

Hepatische Manifestation eines Makrophagen-Aktivierungs-Syndroms (MAS)

P. Galle, A. Schwarting, B. Straub, 2017, Zeitschrift für Gastroenterologie.

Expression and prognostic significance of insulin‑like growth factor-2 receptor in human hepatocellular carcinoma and the influence of transarterial chemoembolization.

P. Galle, G. Otto, H. Lang, 2019, Oncology reports.

Functional inhibition of Oct leads to HNF4α upregulation

D. Schuppan, P. Galle, J. Marquardt, 2021, Experimental and therapeutic medicine.

Deletion of organic cation transporter Oct3 promotes hepatic fibrosis via upregulation of TGFbeta.

D. Schuppan, P. Galle, J. Marquardt, 2019, American journal of physiology. Gastrointestinal and liver physiology.

Ten years of simultaneous pancreas-kidney transplantation: a retrospective single-center analysis of prospectively obtained data.

G. Otto, J. M. Kaths, T. Zimmermann, 2011, Transplantation proceedings.

Downregulation of organic cation transporter 1 (SLC22A1) is associated with tumor progression and reduced patient survival in human cholangiocellular carcinoma.

Marcus Schuchmann, Anca Zimmermann, Tim Zimmermann, 2013, International journal of oncology.

Decision making for transjugular intrahepatic portosystemic stent shunt in refractory ascites and variceal bleeding: MELD, or not MELD, that is the question

G. Otto, C. Düber, R. Kloeckner, 2020, European journal of gastroenterology & hepatology.

Long-term observation of hepatocellular carcinoma recurrence after liver transplantation at a European transplantation centre

P. Galle, G. Otto, J. Marquardt, 2019, United European gastroenterology journal.

Treatment and survival of non-alcoholic steatohepatitis associated hepatocellular carcinoma

P. Galle, G. Otto, J. Schattenberg, 2015, BMC Cancer.

Effectiveness and Safety of Direct-Acting Antiviral Combination Therapies for Treatment of Hepatitis C Virus in Elderly Patients: Results from the German Hepatitis C Registry

M. Muche, T. Berg, S. Zeuzem, 2018, Drugs & Aging.

Prospective evaluation of the impact of covert hepatic encephalopathy on quality of life and sleep in cirrhotic patients

P. Galle, J. Schattenberg, C. Labenz, 2018, Alimentary pharmacology & therapeutics.

Sarcopenia as prognostic factor for survival after orthotopic liver transplantation

P. Galle, D. Zöller, S. Koch, 2019, European journal of gastroenterology & hepatology.

Alcohol and Cannabis Consumption Does Not Diminish Cure Rates in a Real-World Cohort of Chronic Hepatitis C Virus Infected Patients on Opioid Substitution Therapy—Data From the German Hepatitis C-Registry (DHC-R)

S. Mauss, H. Wedemeyer, K. Böker, 2019, Substance abuse : research and treatment.

Progression of transthyretin (TTR) amyloidosis in donors and recipients after domino liver transplantation—a prospective single‐center cohort study

P. Galle, G. Otto, A. Barreiros, 2018, Transplant international : official journal of the European Society for Organ Transplantation.

Expression of chemokine receptor CCR5 correlates with the presence of hepatic molecular metastases in K-ras positive human colorectal cancer

P. Galle, M. Berger, H. Lang, 2011, Journal of Cancer Research and Clinical Oncology.

Ribavirin Improves NK Cell IFNγ Response During Sofosbuvir-based DAA Therapy in HCV-infected Liver Transplant Recipients

E. Geissler, H. Schlitt, J. Marquardt, 2020, Transplantation.

Serum markers of type III and IV procollagen processing predict recurrence of fibrosis in liver transplanted patients

M. Karsdal, D. Schuppan, A. Krag, 2019, Scientific Reports.

SDF1β expression in renal cell carcinoma correlates with grading and infiltration by CD8+ T-cells.

P. Galle, W. Brenner, J. Thüroff, 2011, Anticancer research.

Organic Cation Transporter 1 (OCT1) mRNA expression in hepatocellular carcinoma as a biomarker for sorafenib treatment

P. Galle, J. Schattenberg, S. Koch, 2016, BMC Cancer.

Characterization of the cancer immune microenvironment of Mdr2(abcb4)-/- mice treated with diethylnitrosamine – a novel model close to human hepatocarcinogenesis

D. Schuppan, Yong Ook Kim, T. Zimmermann, 2017 .

[Etiology and complications of liver cirrhosis: data from a German centre].

P. Galle, J. Schattenberg, J. Marquardt, 2014, Deutsche medizinische Wochenschrift.

Antiviral triple therapy with boceprevir in a chronic hepatitis C haemodialysis patient awaiting kidney re-transplantation.

P. Galle, T. Zimmermann, J. Knapstein, 2014, Digestive and Liver Disease.

Mo1658 EVALUATION OF BOWEL CLEANSING EFFICACY IN HOSPITALIZED PATIENT POPULATION USING THE PURE-VU SYSTEM

S. Gross, V. Kushnir, J. Samarasena, 2019, Gastrointestinal Endoscopy.

Identification of RARRES1 as a core regulator in liver fibrosis

S. Dooley, F. Lammert, C. Niehrs, 2012, Journal of Molecular Medicine.

Ghrelin/Leptin-imbalance in patients with primary biliary cirrhosis.

G. Ehninger, M. Breidert, T. Zimmermann, 2004, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

Triple antiviral therapy with telaprevir after liver transplantation: a case series

P. Galle, H. Lang, D. Grimm, 2014 .

Addendum zur S3-Leitlinie „Prophylaxe, Diagnostik und Therapie der Hepatitis-C-Virus-Infektion“

T. Zimmermann, C. Sarrazin, S. Zeuzem, 2020, Zeitschrift für Gastroenterologie.

[Expert recommendations: Hepatitis C and transplantation].

C. Strassburg, T. Berg, S. Beckebaum, 2016, Zeitschrift fur Gastroenterologie.

A Comparative, Multicenter, Observational Study of Medication Adherence in Liver Cirrhosis Patients and Dialysis Patients Using Electronic Event Measurement

J. Lutz, T. Mettang, M. Berres, 2017 .

Metabolic syndrome and its association with fatty liver disease after orthotopic liver transplantation

P. Galle, G. Otto, J. Schattenberg, 2013, Transplant international : official journal of the European Society for Organ Transplantation.

Glecaprevir/pibrentasvir is safe and effective in hepatitis C patients with cirrhosis: Real‐world data from the German Hepatitis C‐Registry

S. Mauss, H. Wedemeyer, T. Zimmermann, 2021, Liver international : official journal of the International Association for the Study of the Liver.