Liang Chen

发表

Discovery of Novel Inhibitor for WNT/β-Catenin Pathway by Tankyrase 1/2 Structure-Based Virtual Screening

Qian Zhou, Jindao Zhang, Bo Li, 2020, Molecules.

FOXM1c promotes oesophageal cancer metastasis by transcriptionally regulating IRF1 expression

G. Cai, Liang Chen, K. Zhao, 2018, Cell proliferation.

GATA6 Exerts Potent Lung Cancer Suppressive Function by Inducing Cell Senescence

Xiaolong Fu, Yahui Tian, Guandi Zeng, 2020, Frontiers in Oncology.

Strategies for developing PD-1 inhibitors and future directions.

Liang Chen, Meng Xu, Wenting Pan, 2022, Biochemical pharmacology.

Discovery of Isoform-Selective Akt3 Degraders Overcoming Osimertinib-Induced Resistance in Non-Small Cell Lung Cancer Cells.

J. Smaill, Liang Chen, A. Patterson, 2022, Journal of medicinal chemistry.

In vivo genome-wide CRISPR screening identifies ZNF24 as a negative NF-κB modulator in lung cancer

Guandi Zeng, Liang Chen, Zhiyi Zhang, 2022, Cell & Bioscience.

Dual cyclin‐dependent kinase 4/6 inhibition by PD‐0332991 induces apoptosis and senescence in oesophageal squamous cell carcinoma cells

Liang Chen, Jingxuan Pan, 2017, British journal of pharmacology.

Genome-wide identification of CDC34 that stabilizes EGFR and promotes lung carcinogenesis

Guang-Biao Zhou, Yongchun Zhou, Liang Chen, 2018, bioRxiv.

Systematic identification of CDC34 that functions to stabilize EGFR and promote lung carcinogenesis

Guang-Biao Zhou, Chen Zhang, Min Wang, 2020, EBioMedicine.

In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis

H. Ji, Luonan Chen, Kwok-Kin Wong, 2018, Proceedings of the National Academy of Sciences.

IRF8 induces senescence of lung cancer cells to exert its tumor suppressive function

Bo Li, Jinxia Liang, Feng Lu, 2019, Cell cycle.

Targeting hyperactive TGFBR2 for treating MYOCD deficient lung cancer

Meng Xu, Biao Yu, Jinxia Liang, 2021, Theranostics.

Blocking interaction between SHP2 and PD‐1 denotes a novel opportunity for developing PD‐1 inhibitors

Chenqi Xu, C. Dong, Yahui Tian, 2020, EMBO molecular medicine.

Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition

Xin Hu, H. Ji, Qingsong Liu, 2019, Nature Communications.

Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition

Xin Hu, H. Ji, Qingsong Liu, 2019, Nature Communications.

Genetically Engineered PD-1 Displaying Nanovesicles for Synergistic Checkpoint Blockades and Chemo-Metabolic Therapy Against Non-Small Cell Lung Cancer.

Bo Li, Jinxia Liang, Guandi Zeng, 2023, Acta biomaterialia.

Inactivation of tumor suppressor gene Clusterin leads to hyperactivation of TAK1-NF-κB signaling axis in lung cancer cells and denotes a therapeutic opportunity

Qing‐Yu He, Guandi Zeng, Qian Zhou, 2020, Theranostics.

Phase separation of EML4–ALK in firing downstream signaling and promoting lung tumorigenesis

H. Ji, Xinhua Feng, Xiumin Yan, 2021, Cell discovery.

An EGFR/PI3K/AKT axis promotes accumulation of the Rac1-GEF Tiam1 that is critical in EGFR-driven tumorigenesis

Z. Fan, Z. Chang, M. Ding, 2015, Oncogene.

6‐Mercaptopurine potently inhibits recruitment of SHP2 by phosphorylated PD‐1 to inhibit PD‐1 signalling and enhance T cell function

Guandi Zeng, Liang Chen, Lu Liu, 2023, Immunology.