H. Kase

发表

Inhibitors of calmodulin and protein kinase C block different phases of hippocampal long-term potentiation

Hiroshi Kase, Klaus G. Reymann, K. Reymann, 1988, Brain Research.

2-Hydroxysagamicin: a new antibiotic produced by mutational biosynthesis of Micromonospora sagamiensis.

H. Kase, S. Kitamura, Y. Odakura, 1982, The Journal of antibiotics.

KT5926, a potent and selective inhibitor of myosin light chain kinase.

S. Nakanishi, H. Kase, K. Yamada, 1990, Molecular pharmacology.

Progress in pursuit of therapeutic A2A antagonists: the adenosine A2A receptor selective antagonist KW6002: research and development toward a novel nondopaminergic therapy for Parkinson's disease.

M. Ochi, R. Hauser, T. Chase, 2003, Neurology.

Industry forum: Progress in pursuit of therapeutic A2A antagonists

Hiroshi Kase, H. Kase, 2003, Neurology.

Depletion of ryanodine-sensitive Ca2+ store activates Ca2+ entry in rat submandibular gland acinar cells.

M. Wakui, H. Kase, Y. Fukushi, 1996, The Tohoku journal of experimental medicine.

An On-Site Serology Monitoring System Consisting of a Multiplex Microfluidic Chip Fabricated Using the Electrospray Deposition Method for Laboratory Mice

Y. Yamagata, F. Ike, H. Kase, 2012 .

Chapter 12 – Selective Adenosine A2AReceptor Antagonism as an Alternative Therapy for Parkinson's Disease: A Study in Nonhuman Primates

L. Grégoire, P. Bédard, R. Grondin, 2000 .

A new cyclic nucleotide phosphodiesterase isozyme expressed in the T-lymphocyte cell lines.

H. Kase, M. Ichimura, 1993, Biochemical and biophysical research communications.

Studies on lipoxygenase inhibitors. I. MY3-469 (3-methoxytropolone), a potent and selective inhibitor of 12-lipoxygenase, produced by Streptoverticillium hadanonense KY11449.

H. Kase, S. Kitamura, T. Iida, 1986, The Journal of antibiotics.

Evaluation of [4‐O‐methyl‐11C]KW‐6002 as a potential PET ligand for mapping central adenosine A2A receptors in rats

D. Brooks, S. Luthra, S. Osman, 2001, Synapse.

KF17837 ((E)-8-(3,4-dimethoxystyryl)-1,3-dipropyl-7-methylxanthine), a potent and selective adenosine A2 receptor antagonist.

H. Kase, J. Shimada, M. Ichimura, 1994, European journal of pharmacology.

Adenosine A2A-receptor antagonists: beyond dopaminergic therapies for Parkinson's disease

P. Jenner, H. Kase, A. Mori, 2004 .

Binding of [3H]KF17837S, a selective adenosine A2 receptor antagonist, to rat brain membranes.

T. Shindou, H. Kase, A. Mori, 1994, Molecular pharmacology.

Polyamine Oxidase and Acrolein as Novel Biochemical Markers for Diagnosis of Cerebral Stroke

K. Kashiwagi, N. Saeki, K. Igarashi, 2005, Stroke.

Radioligand binding characteristics of the endothelin receptor in the rabbit iris.

T. Yoshitomi, S. Ishikawa, H. Kase, 1998, Japanese journal of pharmacology.

Potent and selective inhibitors of platelet-derived growth factor receptor phosphorylation. 1. Synthesis, structure-activity relationship, and biological effects of a new class of quinazoline derivatives.

K. Matsuno, Jin-Chen Yu, N. Giese, 2002, Journal of medicinal chemistry.

Stimulatory and inhibitory actions of VIP and cyclic AMP on cytoplasmic Ca2+ signal generation in pancreatic acinar cells

O. Petersen, M. Wakui, H. Kase, 1991, Pflügers Archiv.

HS-142-1, a novel nonpeptide atrial natriuretic peptide (ANP) antagonist, blocks ANP-induced renal responses through a specific interaction with guanylyl cyclase-linked receptors.

Y. Matsuda, T. Inagami, H. Kase, 1992, European journal of pharmacology.

Microbial polysaccharide, HS-142-1, competitively and selectively inhibits ANP binding to its guanylyl cyclase-containing receptor.

Y. Matsuda, H. Kase, Y. Saitoh, 1991, Biochemical and biophysical research communications.

Production of L-Threonine by Analog-resistant Mutants

H. Kase, K. Nakayama, 1972 .

L-Isoleucine production by analog-resistant mutants derived from threonine-producing strain of Corynebacterium glutamicum.

H. Kase, K. Nakayama, 1977 .

Studies on lipoxygenase inhibitors. II. KF8940 (2-n-heptyl-4-hydroxyquinoline-N-oxide), a potent and selective inhibitor of 5-lipoxygenase, produced by Pseudomonas methanica.

H. Kase, S. Kitamura, T. Iida, 1986, The Journal of antibiotics.

Parallel inhibition of platelet-activating factor-induced protein phosphorylation and serotonin release by K-252a, a new inhibitor of protein kinases, in rabbit platelets.

H. Kase, K. Iwahashi, K. Yamada, 1988, Biochemical pharmacology.

Adenosine A2a Receptor‐Mediated Modulation of Striatal Acetylcholine Release In Vivo

H. Kase, K. Koga, M. Kurokawa, 1996, Journal of neurochemistry.

Assay of myosin light chain kinase activity by high-performance liquid chromatography using a synthetic peptide as substrate.

S. Nakanishi, Y. Matsuda, H. Kase, 1991, Analytical biochemistry.

The effect of K-252a, a potent microbial inhibitor of protein kinase, on activated cyclic nucleotide phosphodiesterase.

S. Nakanishi, Y. Matsuda, H. Kase, 1988, The Biochemical journal.

K-252a, a novel microbial product, inhibits smooth muscle myosin light chain kinase.

Y. Nonomura, S. Nakanishi, H. Kase, 1988, The Journal of biological chemistry.

l-Methionine Production by Methionine Analog-resistant Mutants Of Corynebacterium glutamicum

H. Kase, K. Nakayama, 1975 .

The regulation of L-methionine synthesis and the properties of cystathionine .ALPHA.-synthase and .BETA.-cystathionase in Corynebacterium glutamicum.

H. Kase, K. Nakayama, 1974 .

Fermentation production of L-methionine and regulation of L-methionine biosynthesis on Corynebacterium glutamicum. I. Production of O-acetyl-L-homoserine by methionine analogresisttant mutants and regulation of homoserine-O-transacetylase in Corynebacterium glutamicum.

H. Kase, K. Nakayama, 1974 .

KS-505a, a novel inhibitor of bovine brain Ca2+ and calmodulin-dependent cyclic-nucleotide phosphodiesterase from Streptomyces argenteolus.

I. Kawamoto, S. Nakanishi, H. Kase, 1992, The Journal of antibiotics.

K-259-2, a new inhibitor of Ca2+ and calmodulin-dependent cyclic nucleotide phosphodiesterase from Micromonospora olivasterospora.

I. Kawamoto, Y. Matsuda, K. Asano, 1987, The Journal of antibiotics.

New bronchodilators. 3. Imidazo[4,5-c][1,8]naphthyridin-4(5H)-ones.

H. Kase, S. Kitamura, M. Ichimura, 1992, Journal of medicinal chemistry.

Neurite formation in NG108-15 neuroblastoma x glioma hybrid cells by KS-505a, a potent inhibitor of brain cyclic nucleotide phosphodiesterase.

S. Nakanishi, Y. Matsuda, H. Kase, 1993, The Journal of antibiotics.

KS-619-1, a new inhibitor of Ca2+ and calmodulin-dependent cyclic nucleotide phosphodiesterase from Streptomyces californicus.

Y. Matsuda, H. Kase, 1987, The Journal of antibiotics.

Muscarinic receptor subtypes in feline tracheal submucosal gland secretion.

H. Sasaki, T. Takishima, T. Masuda, 1992, The American journal of physiology.

RES-701-1, a novel, potent, endothelin type B receptor-selective antagonist of microbial origin.

Y. Matsuda, T. Tanaka, T. Tanaka, 1994, Molecular pharmacology.

Studies of cardiotonic agents. 8. Synthesis and biological activities of optically active 6-(4-(benzylamino)-7-quinazolinyl)-4,5-dihydro-5-methyl-3(2H)- pyridazinone (KF15232).

K. Kubo, K. Nagashima, H. Kase, 1996, Journal of medicinal chemistry.

K-252a, a potent inhibitor of protein kinase C from microbial origin.

Y. Matsuda, H. Kase, H Kase, 1986, The Journal of antibiotics.

Novel Amido-Bridged Dinuclear Iridium(III) and Iridium(II) Complexes. Synthesis and Characterization of [Cp*Ir(μ2-NHC6H4R-p)3IrCp*]Cl (Cp* = η5-C5Me5; R = Me, H, Cl, CF3), [Cp*Ir{(μ2-NH)2C10H6-1,8}(μ2-X)IrCp*]X (X = Cl, Br), Cp*Ir{(μ2-NH)2C10H6-1,8}IrCp*, and [Cp*Ir{(μ2-NH)2C10H6-1,8}(μ2-H)IrCp*]O2C

S. Kitagawa, H. Kase, H. Matsuzaka, 1997 .

K-26, a novel inhibitor of angiotensin I converting enzyme produced by an actinomycete K-26.

H. Kase, K. Nakayama, A. Karasawa, 1986, The Journal of antibiotics.

K-4, a novel inhibitor of angiotensin I converting enzyme produced by Actinomadura spiculosospora.

H. Kase, K. Nakayama, M. Yamato, 1986, The Journal of antibiotics.

Differential effects of protein kinase inhibitors on pre-established long-term potentiation in rat hippocampal neurons in vitro

Hiroshi Kase, Klaus G. Reymann, K. Reymann, 1991, Neuroscience Letters.

K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases.

C. Murakata, S. Nakanishi, Y. Matsuda, 1987, Biochemical and biophysical research communications.

Activation of a K‐252b‐Sensitive Protein Kinase is Necessary for a Post‐Synaptic Phase of Long‐Term Potentiation in Area CA1 of Rat Hippocampus

K. Reymann, G. Collingridge, S. Davies, 1990, The European journal of neuroscience.

Wortmannin, a microbial product inhibitor of myosin light chain kinase.

I. Takahashi, S. Nakanishi, Y. Matsuda, 1992, The Journal of biological chemistry.

Simple colorimetric cell-cell adhesion assay using MTT-stained leukemia cells.

I. Miki, H. Kase, N. Ishihara, 1993, Journal of immunological methods.

Distribution of adenosine A2A receptor antagonist KW-6002 and its effect on gene expression in the rat brain

H. Kase, A. Mori, S. Aoyama, 2002, Brain Research.

Biosynthesis of astromicin and related antibiotics. II. Biosynthetic studies with blocked mutants of Micromonospora olivasterospora.

H. Kase, Y. Odakura, K. Shirahata, 1984, The Journal of antibiotics.

KS-501 and KS-502, new inhibitors of Ca2+ and calmodulin-dependent cyclic-nucleotide phosphodiesterase from Sporothrix sp.

I. Kawamoto, S. Nakanishi, H. Kase, 1989, The Journal of antibiotics.

Phorbol ester-induced hippocampal long-term potentiation is counteracted by inhibitors of protein kinase C

K. Reymann, K. Schulzeck, H. Kase, 2004, Experimental Brain Research.

Biotransformation of Sisomicin and Verdamicin by Micromonospora sagamiensis

H. Kase, T. Iida, K. Nakayama, 1982 .

Accumulation of 2-deoxy-scyllo-inosamine by a 2-deoxystreptamine-requiring idiotroph of Micromonospora sagamiensis.

H. Kase, Y. Odakura, T. Iida, 1980, The Journal of antibiotics.

Sagamicin and the related aminoglycosides: fermentation and biosynthesis. III. Isolation and characterization of Micromonospora sagamiensis mutants blocked in gentamicin C1 pathway.

H. Kase, Y. Odakura, K. Nakayama, 1983, The Journal of antibiotics.

Production of antibiotic SU-2 complex by a 2-deoxystreptamine idiotroph of Micromonospora sagamiensis.

H. Kase, S. Kitamura, K. Nakayama, 1982, The Journal of antibiotics.

Sagamicin and the related aminoglycosides: fermentation and biosynthesis. I. Biosynthetic studies with the blocked mutants of Micromonospora sagamiensis.

H. Kase, Y. Odakura, K. Nakayama, 1982, The Journal of antibiotics.

The structures of aminoglycoside antibiotics, SU-1, 2, and 3.

H. Kase, S. Kitamura, T. Iida, 1982, The Journal of antibiotics.

Adenosine A2A Antagonist: A novel antiparkinsonian agent that does not provoke dyskinesia in Parkinsonian monkeys

P. Jenner, R. Pearce, H. Kase, 1998, Annals of neurology.

Biosynthesis of astromicin and related antibiotics. I. Biosynthetic studies by bioconversion experiments.

H. Kase, Y. Odakura, T. Iida, 1984, The Journal of antibiotics.

Rescue of Locomotor Impairment in Dopamine D2 Receptor-Deficient Mice by an Adenosine A2A Receptor Antagonist

Hiroshi Kase, E. Borrelli, H. Kase, 2000, The Journal of Neuroscience.

Inhibition of calmodulin-dependent cyclic nucleotide phosphodiesterase by flunarizine, a calcium-entry blocker.

Y. Matsuda, K. Kubo, H. Kase, 1984, Biochemical and biophysical research communications.

K-252b, c and d, potent inhibitors of protein kinase C from microbial origin.

S. Nakanishi, Y. Matsuda, H. Kase, 1986, The Journal of antibiotics.

In vivo regulation of acetylcholine release via adenosine A1 receptor in rat cerebral cortex

H. Kase, S. Shiozaki, M. Kurokawa, 1996, Neuroscience Letters.

Cytoplasmic Ca+ signals evoked by activation of cholecystokinin receptors: Ca2+-Dependent current recording in internally perfused pancreatic acinar cells

O. Petersen, M. Wakui, H. Kase, 1991, The Journal of Membrane Biology.

Knockout Mice in the Study of Dopaminergic Diseases

J. Baik, E. Borrelli, H. Kase, 2000 .

Differences in activities of thromboxane A2 receptor antagonists in smooth muscle cells.

I. Miki, H. Kase, A. Ishii, 1992, European journal of pharmacology.

Adenosine A2A receptor antagonists as new agents for the treatment of Parkinson's disease.

P. Jenner, P. Richardson, H. Kase, 1997, Trends in pharmacological sciences.

Production of O-Succinyl-L-homoserine by Auxotrophic Mutants of Aerobacter aerogenes

S. Kinoshita, H. Kase, K. Nakayama, 1970 .

Unique binding pocket for KW-4679 in the histamine H1 receptor.

H. Kase, M. Ichimura, H. Nonaka, 1998, European journal of pharmacology.

KW-4679, an antiallergic drug, inhibits the production of inflammatory lipids in human polymorphonuclear leukocytes and guinea pig eosinophils.

I. Miki, H. Ishii, H. Kase, 1996, International archives of allergy and immunology.

Introductory Remarks: Adenosine A2A Receptor Antagonists: A Novel Approach to the Treatment of Parkinson's Disease

H. Kase, 2000 .

Positron emission tomography analysis of [11C]KW‐6002 binding to human and rat adenosine A2A receptors in the brain

D J Brooks, S Osman, D. Brooks, 2008, Synapse.

Inhibition by KF17837 of adenosine A2A receptor‐mediated modulation of striatal GABA and ACh release

H. Kase, M. Kurokawa, I. Kirk, 1994, British journal of pharmacology.

Isolation and Purification of HS-142-1, a Novel Nonpeptide Antagonist for the Atrial Natriuretic Peptide Receptor, from Aureobasidium sp.

I. Kawamoto, Y. Matsuda, H. Sano, 1991 .

K-13, a novel inhibitor of angiotensin I converting enzyme produced by Micromonospora halophytica subsp. exilisia. I. Fermentation, isolation and biological properties.

M. Kaneko, H. Kase, K. Yamada, 1987, The Journal of antibiotics.

Combined Use of the Adenosine A2A Antagonist KW-6002 with l -DOPA or with Selective D1 or D2 Dopamine Agonists Increases Antiparkinsonian Activity but Not Dyskinesia in MPTP-Treated Monkeys

P. Jenner, R. Pearce, H. Kase, 2000, Experimental Neurology.

Adenosine A2A receptor-mediated modulation of GABA and glutamate release in the output regions of the basal ganglia in a rodent model of Parkinson's disease

M. Ochi, H. Kase, S. Shiozaki, 2004, Neuroscience.

Presynaptic adenosine A2A receptors enhance GABAergic synaptic transmission via a cyclic AMP dependent mechanism in the rat globus pallidus

Hiroshi Kase, Michio Ichimura, Akihisa Mori, 2002, British journal of pharmacology.

Adenosine A2A receptor enhances GABAA‐mediated IPSCs in the rat globus pallidus

T. Shindou, H. Kase, A. Mori, 2001, The Journal of physiology.

Antiparkinsonian effect of a new selective adenosine A2A receptor antagonist in MPTP-treated monkeys

L. Grégoire, R. Grondin, A. Tahar, 1999, Neurology.

Mechanism of L-Threonine and L-Lysine Production by Analog-resistant Mutants of Corynebacterium glutamicum

Hiroshi Kase, Kiyoshi Nakayama, H. Kase, 1974 .

KS-504 compounds, novel inhibitors of Ca2+ and calmodulin-dependent cyclic nucleotide phosphodiesterase from Mollisia ventosa.

I. Kawamoto, S. Nakanishi, H. Sano, 1989, The Journal of antibiotics.

K252a, a new inhibitor of protein kinase C, concomitantly inhibits 40K protein phosphorylation and serotonin secretion in a phorbol ester-stimulated platelets.

H. Kase, K. Iwahashi, K. Yamada, 1987, Biochemical and biophysical research communications.

Microbial production of essential amino acid with Corynebacterium glutamicum mutants.

H. Kase, K. Nakayama, K. Araki, 1978, Advances in experimental medicine and biology.

Adenosine receptors and Parkinson's disease

P. Jenner, P. Richardson, H. Kase, 1999 .

MY336-a, a novel beta-adrenergic receptor antagonist produced by Streptomyces gabonae.

K. Kubo, H. Kase, K. Shuto, 1986, Journal of antibiotics (Tokyo. 1968).

KW‐3902, a selective high affinity antagonist for adenosine A1 receptors

H. Kase, T. Kanda, J. Shimada, 1996, British journal of pharmacology.

Adenosine A2A antagonists with potent anti-cataleptic activity

Hiroshi Kase, Joji Nakamura, Michio Ichimura, 1997 .

The role of adenosine A2a receptors in regulating GABAergic synaptic transmission in striatal medium spiny neurons.

T. Shindou, H. Kase, A. Mori, 1996, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Anti-inflammatory and bronchodilator properties of KF19514, a phosphodiesterase 4 and 1 inhibitor.

H. Kase, S. Kitamura, M. Ichimura, 1997, European journal of pharmacology.

Photoisomerization of a potent and selective adenosine A2 antagonist, (E)-1,3-Dipropyl-8-(3,4-dimethoxystyryl)-7-methylxanthine.

H. Kase, J. Shimada, N. Koike, 1993, Journal of medicinal chemistry.

New Aspects of Physiological and Pathophysiological Functions of Adenosine A2A Receptor in Basal Ganglia

H. Kase, 2001, Bioscience, biotechnology, and biochemistry.

Systemic administration of adenosine A2A receptor antagonist reverses increased GABA release in the globus pallidus of unilateral 6-hydroxydopamine-lesioned rats: a microdialysis study

M. Ochi, H. Kase, K. Koga, 2000, Neuroscience.

ReviewNew Aspects of Physiological of Adenosine A 2 A Receptor inand Pathophysiological Basal Ganglia Functions JS , su

H. Kase, H. Kaser, 2017 .

Cytoplasmic Ca2+ signals evoked by activation of cholecystokinin receptors: Ca(2+)-dependent current recording in internally perfused pancreatic acinar cells.

O. Petersen, M. Wakui, H. Kase, 1991, Journal of Membrane Biology.

Antiinflammatory and antiallergic effects of a novel metabolite of Nocardiopsis sp. as a potent protein kinase C inhibitor from microbial origin.

H. Ishii, H. Kase, T. Tamura, 1988, Arzneimittel-Forschung.

L‐DOPA‐induced modulation of GABA and glutamate release in substantia nigra pars reticulata in a rodent model of Parkinson's disease

M. Ochi, H. Kase, S. Shiozaki, 2004, Synapse.

Adenosine modulates the striatal GABAergic inputs to the globus pallidus via adenosine A2A receptors in rats

T. Shindou, P. Richardson, H. Kase, 2003, Neuroscience Letters.

Antiparkinsonian activity of adenosine A2A antagonists in experimental models.

M. Ochi, P. Jenner, R. Pearce, 1999, Advances in neurology.

Distribution of adenosine A(2A) receptor antagonist KW-6002 and its effect on gene expression in the rat brain.

H. Kase, A. Mori, S. Aoyama, 2002, Brain research.

Adenosine A(2A) receptor-mediated modulation of GABA and glutamate release in the output regions of the basal ganglia in a rodent model of Parkinson's disease.

M. Ochi, H. Kase, S. Shiozaki, 2004, Neuroscience.

Richardson et al. reply

P. Jenner, P. Richardson, H. Kase, 1998 .

Gold sodium thiomalate down-regulates intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 expression on vascular endothelial cells.

N. Miyasaka, I. Miki, I. Saito, 1994, Molecular pharmacology.

Essential role of aspartokinase in L-threonine production by Escherichia coli W mutants.

T. Mizukami, H. Kase, M. Yagisawa, 1986 .