G. Drummond

C. Sobey, B. Broughton, K. Jackman, 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

C. Sobey, B. Broughton, G. Drummond, 2011, Brain Research.

Brain infarct volume after permanent focal ischemia is not dependent on Nox2 expression

C. Sobey, Hyun Ah Kim, G. Drummond, 2012, Brain Research.

Reconstituted High-Density Lipoproteins Inhibit the Acute Pro-Oxidant and Proinflammatory Vascular Changes Induced by a Periarterial Collar in Normocholesterolemic Rabbits

P. Barter, G. Dusting, K. Rye, 2005, Circulation.

Reactive Oxygen species and cerebrovascular diseases

C. Sobey, S. Chrissobolis, G. Drummond, 2014 .

Oxidative stress and endothelial dysfunction

C. Sobey, G. Drummond, S. D. Dios, 2010 .

Modulation of expression of endothelial nitric oxide synthase by nordihydroguaiaretic acid, a phenolic antioxidant in cultured endothelial cells.

D. Harrison, S. Parthasarathy, G. Drummond, 1999, Molecular pharmacology.

PB1-F2 Peptide Derived from Avian Influenza A Virus H7N9 Induces Inflammation via Activation of the NLRP3 Inflammasome*

E. Latz, M. Tate, J. McAuley, 2016, Journal of Biological Chemistry.

Inhibition of Nox2 Oxidase Activity Ameliorates Influenza A Virus-Induced Lung Inflammation

J. Stambas, S. Bozinovski, R. Vlahos, 2011, PLoS pathogens.

Successful Renal Denervation Decreases the Platelet Activation Status in Hypertensive Patients.

K. Peter, M. Esler, D. Hering, 2019, Cardiovascular research.

Self-renewing tissue-resident endothelial-macrophage progenitor cells originate from yolk sac and are a local source of inflammation and neovascularization in postnatal aorta

Aaron Long, S. Nicholls, A. Misra, 2021 .

NOX1 deficiency in apolipoprotein E-knockout mice is associated with elevated plasma lipids and enhanced atherosclerosis

C. Sobey, B. Broughton, G. Drummond, 2015, Free radical research.

Nox1 upregulates the function of vascular T-type calcium channels following chronic nitric oxide deficit

C. Hill, K. Matthaei, G. Drummond, 2015, Pflügers Archiv - European Journal of Physiology.

Endothelial NADPH oxidases: which NOX to target in vascular disease?

C. Sobey, G. Drummond, 2014, Trends in Endocrinology & Metabolism.

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

C. Sobey, K. Griendling, G. Drummond, 2011, Nature Reviews Drug Discovery.

Nox isoforms in vascular pathophysiology: insights from transgenic and knockout mouse models

C. Sobey, G. Drummond, A. Walduck, 2010, Redox report : communications in free radical research.

Importance of NOX1 for angiotensin II-induced cerebrovascular superoxide production and cortical infarct volume following ischemic stroke

C. Sobey, K. Jackman, G. Drummond, 2009, Brain Research.

Diagnosing and Treating Hypertensive Disorders of Pregnancy? The Answer May Now Be Less BAFF-ling.

C. Sobey, Antony Vinh, G. Drummond, 2017, Hypertension.

Glucose-6-phosphate dehydrogenase contributes to the regulation of glucose uptake in skeletal muscle

Nolan J. Hoffman, M. Febbraio, P. Iliades, 2016, Molecular metabolism.

Angiotensin (1-7) as a therapy to prevent rupture of intracranial aneurysms?

C. Sobey, S. Kuruppu, G. Drummond, 2014, Hypertension.

Reactive Oxygen Species in the Cerebral Circulation

C. Sobey, T. Paravicini, G. Drummond, 2012, Drugs.

The contribution of Nox4 to NADPH oxidase activity in mouse vascular smooth muscle.

G. Dusting, G. Drummond, N. Guzzo-Pernell, 2005, Cardiovascular research.

Distinct Redox Signalling following Macrophage Activation Influences Profibrotic Activity

Antony Vinh, G. Drummond, C. Samuel, 2019, Journal of immunology research.

Aldosterone and the mineralocorticoid receptor in the cerebral circulation and stroke

T. Arumugam, C. Sobey, M. Young, 2012, Experimental & Translational Stroke Medicine.

Reduced cerebrovascular remodeling and functional impairment in spontaneously hypertensive rats following combined treatment with suboptimal doses of telmisartan and ramipril: is less really more?

C. Sobey, G. Drummond, K. Budzyn, 2010, Journal of hypertension.

Role of CCR2 in Inflammatory Conditions of the Central Nervous System

T. Arumugam, C. Sobey, M. Gelderblom, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

A call to action for new global approaches to cardiovascular disease drug solutions.

R. Califf, F. Crea, J. Freedman, 2021, European heart journal.

A Call to Action for New Global Approaches to Cardiovascular Disease Drug Solutions.

R. Califf, F. Crea, J. Freedman, 2021, Circulation.

CEACAM1: an adhesion molecule that limits blood-brain barrier damage by neutrophils after stroke.

C. Sobey, G. Drummond, 2013, Circulation research.

Gender influences cerebral vascular responses to angiotensin II through Nox2‐derived reactive oxygen species

C. Sobey, B. Broughton, G. Drummond, 2009, Stroke.

eNOS-overexpressing mice: too much NO makes the blood pressure low.

D. Harrison, G. Drummond, 1998, The Journal of clinical investigation.

Myocardial oxidative stress contributes to transgenic β2‐adrenoceptor activation‐induced cardiomyopathy and heart failure

A. Dart, R. Ritchie, Xiao-Ming Gao, 2011, British journal of pharmacology.

The IL-18/IL-18R1 signalling axis: Diagnostic and therapeutic potential in hypertension and chronic kidney disease.

C. Sobey, Antony Vinh, G. Drummond, 2022, Pharmacology & therapeutics.

Effect of a Selective Mas Receptor Agonist in Cerebral Ischemia In Vitro and In Vivo

C. Sobey, Hyun Ah Kim, R. Widdop, 2015, PloS one.

Deficiency of Prebiotic Fiber and Insufficient Signaling Through Gut Metabolite-Sensing Receptors Leads to Cardiovascular Disease

T. Spector, C. Mackay, A. El-Osta, 2020, Circulation.

G protein‐coupled estrogen receptor 1: a novel target to treat cardiovascular disease in a sex‐specific manner?

T. Arumugam, C. Sobey, Antony Vinh, 2021 .

Anakinra reduces blood pressure and renal fibrosis in one kidney/DOCA/salt‐induced hypertension

E. Latz, C. Sobey, A. Mansell, 2017, Pharmacological research.

NOX2 oxidase expressed in endosomes promotes cell proliferation and prostate tumour development

C. Sobey, D. Brooks, E. Williams, 2018, Oncotarget.

Adjustment for body mass index changes inverse associations of HDL-cholesterol with blood pressure and hypertension to positive associations

J. Golledge, C. Sobey, P. Witting, 2021, Journal of Human Hypertension.

Synthesis of six mexiletine derivatives with isoindolines attached as potential antioxidants and their evaluation as cardioprotective agents

W. R. Jackson, P. White, C. Wright, 2015 .

Sex-Dependent Effects of G Protein–Coupled Estrogen Receptor Activity on Outcome After Ischemic Stroke

T. Arumugam, C. Sobey, B. Broughton, 2014, Stroke.

Stroke Increases G Protein-Coupled Estrogen Receptor Expression in the Brain of Male but Not Female Mice

Sung-Chun Tang, T. Arumugam, C. Sobey, 2012, Neurosignals.

Unexpected anti-hypertrophic responses to low-level stimulation of protease-activated receptors in adult rat cardiomyocytes

R. Ritchie, G. Dusting, A. Fender, 2014, Naunyn-Schmiedeberg's Archives of Pharmacology.

UNEXPECTED ANTIHYPERTROPHIC RESPONSES TO LOW-LEVEL STIMULATION OF PROTEASE-ACTIVATED RECEPTORS IN ADULT RAT CARDIOMYOCYTES

R. Ritchie, G. Dusting, A. Fender, 2014 .

Using machine learning to ace cardiovascular risk tests.

G. Figtree, J. Bell, G. Drummond, 2020, Cardiovascular research.

Evidence That Ly6Chi Monocytes Are Protective in Acute Ischemic Stroke by Promoting M2 Macrophage Polarization

C. Sobey, B. Broughton, G. Drummond, 2015, Stroke.

Evidence That Ly 6 Chi Monocytes Are Protective in Acute Ischemic Stroke by Promoting M 2 Macrophage Polarization

C. Sobey, B. Broughton, Hyun Ah Kim, 2022 .

Diastolic dysfunction in a pre-clinical model of diabetes is associated with changes in the cardiac non-myocyte cellular composition

A. Murphy, D. Prakoso, R. Ritchie, 2021, Cardiovascular Diabetology.

Obligatory Role for B Cells in the Development of Angiotensin II–Dependent Hypertension

K. Peter, C. Sobey, P. Tipping, 2015, Hypertension.

3´, 4´-Dihydroxyflavonol Enhances Nitric Oxide Bioavailability and Improves Vascular Function after Ischemia and Reperfusion Injury in the Rat

O. Woodman, G. Drummond, E. C. Chan, 2003, Journal of cardiovascular pharmacology.

Nox1 Oxidase Suppresses Influenza A Virus-Induced Lung Inflammation and Oxidative Stress

C. Sobey, Antony Vinh, S. Bozinovski, 2013, PloS one.

Antioxidant and Nitric Oxide-Sparing Actions of Dihydropyridines and ACE Inhibitors Differ in Human Endothelial Cells

G. Drummond, R. Berkels, H. Lob, 2005, Pharmacology.

Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition

E. Latz, P. Hertzog, M. Tate, 2016, Scientific Reports.

Role of chemokine RANTES in the regulation of perivascular inflammation, T-cell accumulation, and vascular dysfunction in hypertension

D. Harrison, Antony Vinh, T. Guzik, 2016, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Adventitial application of the NADPH oxidase inhibitor apocynin in vivo reduces neointima formation and endothelial dysfunction in rabbits.

G. Dusting, Elsa C Chan, R. Dilley, 2007, Cardiovascular research.

Nitric oxide suppresses NADPH oxidase-dependent superoxide production by S-nitrosylation in human endothelial cells.

G. Dusting, H. Peshavariya, G. Drummond, 2007, Cardiovascular research.

Increased NADPH Oxidase Activity, gp91phox Expression, and Endothelium-Dependent Vasorelaxation During Neointima Formation in Rabbits

G. Dusting, T. Paravicini, G. Drummond, 2002, Circulation research.

Nox2 Oxidase Activity Accounts for the Oxidative Stress and Vasomotor Dysfunction in Mouse Cerebral Arteries following Ischemic Stroke

C. Sobey, G. Drummond, T. M. De Silva, 2011, PloS one.

Nitroxyl (HNO) reduces endothelial and monocyte activation and promotes M2 macrophage polarization.

K. Andrews, O. Huet, D. Michell, 2016, Clinical science.

Endothelium-dependent relaxation to the B1 kinin receptor agonist des-Arg9-bradykinin in human coronary arteries.

T. Cocks, G. Drummond, 1995, British journal of pharmacology.

SPECIAL REPORT Endothelium‐dependent relaxation to the B1 kinin receptor agonist des‐Arg ‐bradykinin in human coronary arteries

T. Cocks, G. Drummond, 1995 .

Novel isoforms of NADPH oxidase in vascular physiology and pathophysiology

G. Dusting, G. Drummond, L. Gulluyan, 2003, Clinical and experimental pharmacology & physiology.

Apamin‐sensitive, non‐nitric oxide (NO) endothelium‐dependent relaxations to bradykinin in the bovine isolated coronary artery: no role for cytochrome P450 and K+

T. Cocks, G. Drummond, S. Selemidis, 2000, British journal of pharmacology.

Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE-/- mice.

C. Sobey, G. Dusting, B. Broughton, 2010, American journal of physiology. Heart and circulatory physiology.

Reactive oxygen species in the cerebral circulation: are they all bad?

C. Sobey, G. Drummond, A. Miller, 2006, Antioxidants & redox signaling.

Flow-Induced Cerebral Vasodilatation in Vivo Involves Activation of Phosphatidylinositol-3 Kinase, NADPH-Oxidase, and Nitric Oxide Synthase

C. Sobey, T. Paravicini, G. Drummond, 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Chronic recurrent dehydration associated with periodic water intake exacerbates hypertension and promotes renal damage in male spontaneously hypertensive rats

Victor G. Puelles, R. Evans, Antony Vinh, 2016, Scientific Reports.

Over-Expression of DSCR1 Protects against Post-Ischemic Neuronal Injury

T. Arumugam, C. Sobey, B. Broughton, 2012, PloS one.

Evidence that nitric oxide inhibits vascular inflammation and superoxide production via a p47phox‐dependent mechanism in mice

C. Sobey, G. Drummond, S. Selemidis, 2010, Clinical and experimental pharmacology & physiology.

Nitroxyl (HNO) suppresses vascular Nox2 oxidase activity.

C. Sobey, S. Chrissobolis, G. Drummond, 2013, Free radical biology & medicine.

Neuroprotective effect of an angiotensin receptor type 2 agonist following cerebral ischemia in vitro and in vivo

T. Arumugam, C. Sobey, Hyun Ah Kim, 2012, Experimental & Translational Stroke Medicine.

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy

S. Lewin, J. O’Leary, C. Sobey, 2017, Nature Communications.

Vasorelaxant and antiaggregatory actions of the nitroxyl donor isopropylamine NONOate are maintained in hypercholesterolemia.

C. Sobey, G. Drummond, B. Kemp-Harper, 2011, American journal of physiology. Heart and circulatory physiology.

Antioxidant actions contribute to the antihypertrophic effects of atrial natriuretic peptide in neonatal rat cardiomyocytes.

R. Ritchie, D. Kaye, O. Woodman, 2006, Cardiovascular research.

Evidence for mediation by endothelium‐derived hyperpolarizing factor of relaxation to bradykinin in the bovine isolated coronary artery independently of voltage‐operated Ca2+ channels

T. Cocks, G. Drummond, T. Cocks, 1996, British journal of pharmacology.

Sex hormones, intestinal inflammation, and the gut microbiome: Major influencers of the sexual dimorphisms in obesity

A. Franks, S. Petrovski, Antony Vinh, 2022, Frontiers in Immunology.

Repurposing drugs targeting the P2X7 receptor to limit hyperinflammation and disease during influenza virus infection

M. Tate, A. Mansell, K. E. Lawlor, 2019, British journal of pharmacology.

Pressor response to angiotensin II is enhanced in aged mice and associated with inflammation, vasoconstriction and oxidative stress

C. Sobey, M. Cooper, A. Mansell, 2017, Aging.

NADPH oxidase activity is higher in cerebral versus systemic arteries of four animal species: role of Nox2.

C. Sobey, B. Broughton, G. Drummond, 2009, American journal of physiology. Heart and circulatory physiology.

Endothelium‐dependent relaxations mediated by inducible B1 and constitutive B2 kinin receptors in the bovine isolated coronary artery

G. Drummond, T. Cocks, 1995, British journal of pharmacology.

Antibodies in the Pathogenesis of Hypertension

C. Sobey, B. Toh, A. Bobik, 2014, BioMed research international.

Chlamydia pneumoniae induces a pro‐inflammatory phenotype in murine vascular smooth muscle cells independently of elevating reactive oxygen species

C. Sobey, R. Strugnell, G. Drummond, 2012, Clinical and experimental pharmacology & physiology.

C-type natriuretic peptide (CNP) suppresses plasminogen activator inhibitor-1 (PAI-1) in vivo.

G. Drummond, C. Anderson, M. Kanagasundaram, 2005, Cardiovascular research.

Prior cancer diagnosis and mortality profile in US adults.

C. Sobey, G. Drummond, Yutang Wang, 2022, The American journal of the medical sciences.

Aldosterone-Induced Hypertension is Sex-Dependent, Mediated by T Cells and Sensitive to GPER Activation.

C. Sobey, B. Broughton, Hyun Ah Kim, 2020, Cardiovascular research.

Acute or Delayed Systemic Administration of Human Amnion Epithelial Cells Improves Outcomes in Experimental Stroke

V. Srikanth, T. Phan, T. Arumugam, 2018, Stroke.

The antioxidant tempol inhibits cardiac hypertrophy in the insulin-resistant GLUT4-deficient mouse in vivo.

R. Ritchie, D. Kaye, J. Proietto, 2007, Journal of molecular and cellular cardiology.

Activin and NADPH-oxidase in preeclampsia: insights from in vitro and murine studies.

C. Sobey, E. Wallace, R. Lim, 2015, American journal of obstetrics and gynecology.

Cardiac Tissue Injury and Remodeling Is Dependent Upon MR Regulation of Activation Pathways in Cardiac Tissue Macrophages.

M. Young, G. Tesch, P. Fuller, 2016, Endocrinology.

Y‐chromosome lineage determines cardiovascular organ T‐cell infiltration in the stroke‐prone spontaneously hypertensive rat

K. Andrews, A. Murphy, G. Jennings, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Chronic angiotensin IV treatment reverses endothelial dysfunction in ApoE-deficient mice.

Antony Vinh, R. Widdop, G. Drummond, 2008, Cardiovascular research.

Accumulation of serum lipids by vascular smooth muscle cells involves a macropinocytosis-like uptake pathway and is associated with the downregulation of the ATP-binding cassette transporter A1

C. Sobey, E. Glaros, Shane R Thomas, 2013, Naunyn-Schmiedeberg's Archives of Pharmacology.

Intermittent Fasting Attenuates Hallmark Vascular and Neuronal Pathologies in a Mouse Model of Vascular Cognitive Impairment

T. Arumugam, C. Sobey, D. Jo, 2022, International journal of biological sciences.

Vascular cognitive impairment and Alzheimer’s disease: role of cerebral hypoperfusion and oxidative stress

A. Thrift, V. Srikanth, T. Phan, 2012, Naunyn-Schmiedeberg's Archives of Pharmacology.

Accumulation of serum lipids by vascular smooth muscle cells involves a macropinocytosis-like uptake pathway and is associated with the downregulation of the ATP-binding cassette transporter A1

C. Sobey, E. Glaros, Shane R Thomas, 2013, Naunyn-Schmiedeberg's Archives of Pharmacology.

Induction of Endothelial NO Synthase by Hydrogen Peroxide via a Ca2+/Calmodulin-Dependent Protein Kinase II/Janus Kinase 2–Dependent Pathway

D. Harrison, Michael E. Davis, G. Drummond, 2001, Arteriosclerosis, thrombosis, and vascular biology.

Translating atherosclerosis research from bench to bedside: navigating the barriers for effective preclinical drug discovery

L. May, G. Figtree, J. D. de Haan, 2022, Clinical science.

Potential Efficacy of Amnion Epithelial Cells to Treat Post-stroke Inflammation

C. Sobey, B. Broughton, E. Wallace, 2014 .

Amnion epithelial cells – a novel therapy for ischemic stroke?

T. Phan, C. Sobey, B. Broughton, 2018, Neural regeneration research.

Post-stroke inflammation and the potential efficacy of novel stem cell therapies: focus on amnion epithelial cells

T. Arumugam, C. Sobey, B. Broughton, 2012, Front. Cell. Neurosci..

B2 kinin receptor activation is the predominant mechanism by which trypsin mediates endothelium-dependent relaxation in bovine coronary arteries

T. Cocks, G. Drummond, S. Selemidis, 2008, Naunyn-Schmiedeberg's Archives of Pharmacology.

Evidence that NF-κB and MAPK Signaling Promotes NLRP Inflammasome Activation in Neurons Following Ischemic Stroke

T. Arumugam, S. Baik, C. Sobey, 2017, Molecular Neurobiology.

Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke

M. Mattson, Sung-Chun Tang, T. Arumugam, 2013, Cell Death and Disease.

M. Sleeman, C. Sobey, Z. Andrews, 2015, Endocrinology.

NADPH oxidases as regulators of tumor angiogenesis: current and emerging concepts.

C. Sobey, E. Williams, Antony Vinh, 2012, Antioxidants & redox signaling.

NADPH oxidases in the vasculature: molecular features, roles in disease and pharmacological inhibition.

H. Schmidt, C. Sobey, K. Wingler, 2008, Pharmacology & therapeutics.

Novel isoforms of NADPH-oxidase in cerebral vascular control.

C. Sobey, G. Drummond, A. Miller, 2006, Pharmacology & therapeutics.

Evidence of CCR2-independent transmigration of Ly6Chi monocytes into the brain after permanent cerebral ischemia in mice

C. Sobey, B. Broughton, Hyun Ah Kim, 2016, Brain Research.

M2 macrophage accumulation in the aortic wall during angiotensin II infusion in mice is associated with fibrosis, elastin loss, and elevated blood pressure.

C. Sobey, Antony Vinh, S. Ricardo, 2015, American journal of physiology. Heart and circulatory physiology.

2 macrophage accumulation in the aortic wall during angiotensin II infusion in mice is associated with fibrosis , elastin loss , and elevated blood pressure

C. Sobey, Antony Vinh, S. Ricardo, 2015 .

Reversal of Vascular Macrophage Accumulation and Hypertension by a CCR2 Antagonist in Deoxycorticosterone/Salt-Treated Mice

J. Armitage, C. Sobey, Antony Vinh, 2012, Hypertension.

microRNA-367-3p regulation of GPRC5A is suppressed in ischemic stroke

K. Vickers, A. Remaley, C. Sobey, 2020, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxide.

D. Harrison, M. Davis, G. Drummond, 2000, Circulation research.

Immune Cell Infiltration in Malignant Middle Cerebral Artery Infarction: Comparison with Transient Cerebral Ischemia

T. Arumugam, C. Sobey, M. Gelderblom, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Pathophysiology of blood brain barrier dysfunction during chronic cerebral hypoperfusion in vascular cognitive impairment

T. Arumugam, C. Sobey, Hyun Ah Kim, 2022, Theranostics.

Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension

K. Peter, E. Latz, C. Sobey, 2018, Cardiovascular research.

Innovative Anti-Inflammatory and Pro-resolving Strategies for Pulmonary Hypertension: High Blood Pressure Research Council of Australia Award 2019

A. Hobbs, G. Drummond, T. Scott, 2021, Hypertension.

Shear Stress Regulates Endothelial Nitric Oxide Synthase Expression Through c-Src by Divergent Signaling Pathways

D. Harrison, Michael E. Davis, G. Drummond, 2001, Circulation research.

Oxidative stress and endothelial dysfunction in cerebrovascular disease.

C. Sobey, S. Chrissobolis, G. Drummond, 2011, Frontiers in bioscience.

Increased NADPH-Oxidase Activity and Nox4 Expression During Chronic Hypertension Is Associated With Enhanced Cerebral Vasodilatation to NADPH In Vivo

C. Sobey, T. Paravicini, S. Chrissobolis, 2004, Stroke.

Risk of Major Cardiovascular Events in People with Down Syndrome

V. Srikanth, T. Phan, V. Sundararajan, 2015, PloS one.

NADPH-Induced Contractions of Mouse Aorta Do Not Involve NADPH Oxidase: A Role for P2X Receptors

C. Sobey, G. Dusting, G. Drummond, 2006, Journal of Pharmacology and Experimental Therapeutics.

NOX2β: A Novel Splice Variant of NOX2 That Regulates NADPH Oxidase Activity in Macrophages

C. Sobey, P. King, G. Drummond, 2012, PloS one.

Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt‐induced hypertension in mice

E. Latz, T. Arumugam, C. Sobey, 2016, British journal of pharmacology.

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy

S. Lewin, C. Sobey, P. King, 2017, Nature Communications.

Importance of T Lymphocytes in Brain Injury, Immunodeficiency, and Recovery after Cerebral Ischemia

T. Arumugam, C. Sobey, G. Drummond, 2012, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Immune mechanisms of hypertension

C. Sobey, Antony Vinh, T. Guzik, 2019, Nature Reviews Immunology.

Bacteriophages in Natural and Artificial Environments

A. Franks, C. Sobey, Daniel T. F. Rice, 2019, Pathogens.

Hyperuricemia is independently associated with hypertension in men under 60 years in a general Chinese population

J. Golledge, C. Sobey, F. Charchar, 2020, Journal of Human Hypertension.

Integrative Epigenomic and Transcriptomic Analysis Reveals Robust Metabolic Switching in the Brain During Intermittent Fasting

M. Mattson, B. Kennedy, M. Hande, 2020, bioRxiv.

IL–1β and IL–18: inflammatory markers or mediators of hypertension?

E. Latz, C. Sobey, A. Mansell, 2014, British journal of pharmacology.

Adipose Tissue Compartments, Inflammation, and Cardiovascular Risk in the Context of Depression

D. Hartung, K. Kahl, G. Drummond, 2022, Frontiers in Psychiatry.

Reduced renal function may explain the higher prevalence of hyperuricemia in older people

J. Golledge, C. Sobey, F. Charchar, 2021, Scientific Reports.

Roles of Inflammation, Oxidative Stress, and Vascular Dysfunction in Hypertension

C. Sobey, S. Chrissobolis, G. Drummond, 2014, BioMed research international.

Advanced atherosclerosis is associated with inflammation, vascular dysfunction and oxidative stress, but not hypertension

C. Sobey, D. Ferens, S. Chrissobolis, 2017, Pharmacological research.

IL-18 (Interleukin-18) Produced by Renal Tubular Epithelial Cells Promotes Renal Inflammation and Injury During Deoxycorticosterone/Salt-Induced Hypertension in Mice

M. Hickey, E. Latz, T. Arumugam, 2021, Hypertension.

Integrative epigenomic and transcriptomic analyses reveal metabolic switching by intermittent fasting in brain

M. Mattson, M. Hande, T. Arumugam, 2022, GeroScience.

Diet-induced vitamin D deficiency has no effect on acute post-stroke outcomes in young male mice

T. Arumugam, C. Sobey, G. Zosky, 2017, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Redox control of endothelial function and dysfunction: molecular mechanisms and therapeutic opportunities.

P. Witting, Shane R Thomas, G. Drummond, 2008, Antioxidants & redox signaling.

NADPH oxidase isoform selective regulation of endothelial cell proliferation and survival

C. Sobey, G. Dusting, H. Peshavariya, 2009, Naunyn-Schmiedeberg's Archives of Pharmacology.

Selective inhibition of NADPH-oxidase isoforms as a therapeutic strategy in hypertension

C. Sobey, G. Drummond, A. Miller, 2005 .

Downloaded from http://circres.ahajournals.org / by guest on February 23, 2013Shear Stress Regulates Endothelial Nitric Oxide Synthase Expression Through c-Src by Divergent Signaling Pathways

D. Harrison, Michael E. Davis, G. Drummond, 2001 .

Effect of Gender on NADPH-Oxidase Activity, Expression, and Function in the Cerebral Circulation: Role of Estrogen

H. Schmidt, C. Sobey, G. Drummond, 2007, Stroke.

Dietary fatty acids and mortality risk from heart disease in US adults: an analysis based on NHANES

J. Golledge, C. Sobey, P. Witting, 2023, Scientific Reports.

NADPH Oxidase Activity and Function Are Profoundly Greater in Cerebral Versus Systemic Arteries

H. Schmidt, C. Sobey, G. Drummond, 2005, Circulation research.

Multiomics Analyses Reveal Dynamic Bioenergetic Pathways and Functional Remodeling of the Heart During Intermittent Fasting

M. Mattson, B. Kennedy, T. Arumugam, 2021, bioRxiv.

New opportunities for targeting redox dysregulation in cardiovascular disease.

G. Figtree, G. Drummond, K. Bubb, 2020, Cardiovascular research.

The anti-platelet effects of apocynin in mice are not mediated by inhibition of NADPH oxidase activity

C. Sobey, G. Drummond, J. Arthur, 2010, Naunyn-Schmiedeberg's Archives of Pharmacology.

The Vascular Consequences of Metabolic Syndrome: Rodent Models, Endothelial Dysfunction, and Current Therapies

Christopher G. Sobey, C. Sobey, Antony Vinh, 2020, Frontiers in Pharmacology.

AIM2 inflammasome mediates hallmark neuropathological alterations and cognitive impairment in a mouse model of vascular dementia

P. Wong, D. Hess, M. Lai, 2020, bioRxiv.

The opposing roles of NO and oxidative stress in cardiovascular disease.

C. Sobey, R. Ritchie, G. Drummond, 2017, Pharmacological research.

IL-37 increases in patients after ischemic stroke and protects from inflammatory brain injury, motor impairment and lung infection in mice

Sung-Chun Tang, T. Arumugam, C. Sobey, 2019, Scientific Reports.

Hippocampal transcriptome profiling reveals common disease pathways in chronic hypoperfusion and aging

Michael de Silva, D. Herr, K. Lim, 2021, Aging.

Hippocampal Transcriptome Profiling Reveals Common Disease Pathways in Chronic Hypoperfusion and Ageing

D. Herr, K. Lim, M. Lai, 2020, bioRxiv.

A flow cytometric method for the analysis of macrophages in the vascular wall.

C. Sobey, S. Ricardo, G. Drummond, 2013, Journal of immunological methods.

Experimental Factors Influence Diversity Metrics of the Gut Microbiome in Laboratory Mice

D. Kaye, F. Marques, Hamdi A. Jama, 2023 .

Role of Oxidative Stress in Hypertension

C. Sobey, S. Chrissobolis, G. Drummond, 2017 .

Aldosterone-induced oxidative stress and inflammation in the brain are mediated by the endothelial cell mineralocorticoid receptor

C. Sobey, M. Young, S. Chrissobolis, 2016, Brain Research.

Multiomics analyses reveal dynamic bioenergetic pathways and functional remodeling of the heart during intermittent fasting

M. Mattson, B. Kennedy, T. Arumugam, 2023, bioRxiv.

Myocarditis: causes, mechanisms, and evolving therapies

K. Peter, A. Bobik, T. Kyaw, 2023, Expert opinion on therapeutic targets.

Mild Closed-Head Injury in Conscious Rats Causes Transient Neurobehavioral and Glial Disturbances: A Novel Experimental Model of Concussion.

B. Christie, S. Shultz, C. Sobey, 2019, Journal of neurotrauma.

Pathophysiological Links Between Obesity and Dementia.

C. Sobey, Antony Vinh, G. Drummond, 2023, Neuromolecular medicine.

Immune mechanisms of hypertension

C. Sobey, Antony Vinh, T. Guzik, 2019, Nature Reviews Immunology.

Vasoactive actions of nitroxyl (HNO) are preserved in resistance arteries in diabetes

C. Sobey, R. Ritchie, H. Parkington, 2017, Naunyn-Schmiedeberg's Archives of Pharmacology.

Effect of a Broad-Specificity Chemokine-Binding Protein on Brain Leukocyte Infiltration and Infarct Development

C. Sobey, L. Wise, A. Mercer, 2015, Stroke.

Intermittent Fasting Mitigates Vascular and Neuronal Pathologies in a Mouse Model of Vascular Dementia

T. Arumugam, C. Sobey, D. Jo, 2022, bioRxiv.

Chronic cerebral hypoperfusion: a critical feature in unravelling the etiology of vascular cognitive impairment

Acta Neuropathologica Communications, T. Arumugam, C. Sobey, 2023, Acta Neuropathologica Communications.

Impact of the COVID‐19 pandemic and lockdown restrictions on psychosocial and behavioural outcomes among Australian adults with type 2 diabetes: Findings from the PREDICT cohort study

J. Shaw, P. Zimmet, K. Anstey, 2021, Diabetic medicine : a journal of the British Diabetic Association.

The 'A's and 'O's of NADPH oxidase regulation: a commentary on "Subcellular localization and function of alternatively spliced Noxo1 isoforms".

H. Schmidt, N. Opitz, G. Drummond, 2007, Free radical biology & medicine.

Proteasome inhibition reduces plasma cell and antibody secretion, but not angiotensin II-induced hypertension

C. Sobey, Antony Vinh, A. Bobik, 2023, Frontiers in Cardiovascular Medicine.

Immunity and hypertension: New targets to lighten the pressure

C. Sobey, Antony Vinh, G. Drummond, 2019, British journal of pharmacology.

Vitamin D3 Supplementation Reduces Subsequent Brain Injury and Inflammation Associated with Ischemic Stroke

T. Arumugam, C. Sobey, G. Zosky, 2018, NeuroMolecular Medicine.

Suppression of oxidative stress in the endothelium and vascular wall.

G. Dusting, F. Jiang, G. Drummond, 2004, Endothelium : journal of endothelial cell research.

Nox1 upregulates the function of vascular T-type calcium channels following chronic nitric oxide deficit

C. Hill, K. Matthaei, G. Drummond, 2015, Pflügers Archiv - European Journal of Physiology.

Phase I trial outcome of amnion cell therapy in patients with ischemic stroke (I-ACT)

J. Ly, C. Sobey, Henry Ma, 2023, Frontiers in Neuroscience.

Protection against brain injury after ischemic stroke by intravenous human amnion epithelial cells in combination with tissue plasminogen activator

C. Sobey, Hyun Ah Kim, R. Lim, 2023, Frontiers in neuroscience.

Embryonic origins of bipotent endothelial-macrophage progenitor cells in postnatal aorta

M. Dona, J. Polo, P. Psaltis, 2023, bioRxiv.

Direct evidence for a role of Nox2 in superoxide production, reduced nitric oxide bioavailability and early atherogenesis in ApoE-/- mice

C. Sobey, G. Dusting, B. Broughton, 2010 .

Augmented Superoxide Production By Nox2-Containing NADPH Oxidase Causes Cerebral Artery Dysfunction During Hypercholesterolemia

Christopher G Sobey, C. Sobey, G. Drummond, 2010, Stroke.

Interferon regulatory factor 4 a master regulator of hypertensive kidney fibrosis and inflammation?

A. Bobik, T. Kyaw, G. Drummond, 2023, Journal of hypertension.

Fasting triglycerides are positively associated with cardiovascular mortality risk in people with diabetes

D. Magliano, J. Golledge, C. Sobey, 2022, Cardiovascular research.

Sympathetic Nervous System and Atherosclerosis

C. Sobey, K. Denton, G. Drummond, 2023, International journal of molecular sciences.

Discovery of embryonically derived bipotent endothelial-macrophage progenitor cells in postnatal aorta

M. Dona, J. Polo, P. Psaltis, 2021, bioRxiv.

Association of constipation with increased risk of hypertension and cardiovascular events in elderly Australian patients

C. Sobey, Antony Vinh, A. Bobik, 2023, Scientific reports.

How good are our models of cardiovascular disease? Introducing our themed issue on preclinical models for cardiovascular disease research.

Christopher H George, C. Sobey, G. Drummond, 2022, British journal of pharmacology.

How good are our models of cardiovascular disease?

Christopher H George, C. Sobey, G. Drummond, 2022, British journal of pharmacology.

Proteomic Identification of Interferon-Induced Proteins with Tetratricopeptide Repeats as Markers of M1 Macrophage Polarization.

M. Stone, N. Borg, Antony Vinh, 2018, Journal of proteome research.