P. Roy

发表

Trisubstituted ureas as potent and selective mPGES-1 inhibitors.

N. Méthot, D. Riendeau, Daigen Xu, 2011, Bioorganic & medicinal chemistry letters.

The discovery and synthesis of potent zwitterionic inhibitors of renin.

J. Falgueyret, M. Percival, S. Gagné, 2011, Bioorganic & medicinal chemistry letters.

Industrial Synthesis of Semisynthetic Antibiotics

P. Roy, A. Bruggink, 2001 .

The development of potent non-peptidic PTP-1B inhibitors.

E. Asante-Appiah, Y. Boie, B. Kennedy, 2004, Bioorganic & medicinal chemistry letters.

Identification of prostaglandin D2 receptor antagonists based on a tetrahydropyridoindole scaffold.

D. Denis, Y. Leblanc, G. O'neill, 2008, Bioorganic & medicinal chemistry letters.

Identification of a new biaryl scaffold generating potent renin inhibitors.

C. Bayly, D. McKay, R. Aspiotis, 2010, Bioorganic & medicinal chemistry letters.

A new series of potent LTD4 antagonists in the styrylquinoline class.

J. Gauthier, R. Zamboni, D. Guay, 1993 .

The discovery of a new structural class of potent orally active leukotriene D4 antagonists

R. Young, P. Prasit, A. Ford-hutchinson, 1992 .

Synthetic peptides comprising sequences of the human immunoglobulin E heavy chain capable of releasing histamine.

P. Roy, D. Stanworth, D. Moran, 1979, The Biochemical journal.

Investigation of the reputed inhibition of the Prausnitz-Küstner reaction by the pentapeptide Asp-Ser-Asp-Pro-Arg.

P. Roy, D. Stanworth, D. Moran, 1978, International archives of allergy and applied immunology.

Synthesis and biological evaluation of 5,6-diarylimidazo[2.1-b]thiazole as selective COX-2 inhibitors

D. Riendeau, P. Prasit, C. Brideau, 1997 .

A series of non-quinoline cysLT1 receptor antagonists: SAR study on pyridyl analogs of Singulair.

P. Prasit, J. Gauthier, R. Zamboni, 1998, Bioorganic & medicinal chemistry letters.

From indomethacin to a selective COX-2 inhibitor. Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors.

P. Prasit, C. Chan, S. Charleson, 1997, Advances in experimental medicine and biology.

From indomethacin to a selective COX-2 inhibitor: Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors

C. Bayly, D. Denis, P. Prasit, 1996 .

The Hemetsberger-Knittel Synthesis of Substituted 5-, 6-, and 7-Azaindoles

Y. Leblanc, Zhaoyin Wang, P. Roy, 2005 .

SAR in the alkoxy lactone series: the discovery of DFP, a potent and orally active COX-2 inhibitor.

D. Riendeau, S. Boyce, P. Prasit, 1999, Bioorganic & medicinal chemistry letters.

Synthesis, characterization, and activity of metabolites derived from the cyclooxygenase-2 inhibitor rofecoxib (MK-0966, Vioxx).

D. Riendeau, R. Young, P. Prasit, 2000, Bioorganic & medicinal chemistry letters.

CONDENSATION OF 2-AMINO-5-CHLOROBENZOXAZOLE WITH ALPHA -BROMOKETONES : A MECHANISTIC STUDY

Y. Leblanc, P. Roy, N. Tsou, 1997 .

A new series of selective COX-2 inhibitors : 5,6-diarylthiazolo[3,2-b][1,2,4]triazoles

P. Prasit, C. Brideau, C. Chan, 1997 .

The Use of 3‐Phenylselenobutanal as a Crotonaldehyde Equivalent in Synthesis.

S. Hanessian, P. Roy, S. Sahoo, 1986 .

Synthetic Studies on the Mevinic Acids Using the Chiron Approach: Total Synthesis of (+)-Dihydromevinolin."

S. Hanessian, M. Petrini, P. Roy, 1990 .

SYNTHESIS AND BIOLOGICAL EVALUATION OF BOTH ENANTIOMERS OF L-761,000 AS INHIBITORS OF CYCLOOXYGENASE 1 AND 2

Yves Leblanc, Daniel Guay, Petpiboon Prasit, 1996 .

Further studies on histamine release from rat mast cells in vitro induced by peptides. Characteristics of a synthetic intermediate with potent releasing activity.

P. Roy, D. Stanworth, D. Moran, 1980, The Biochemical journal.

The structure of PTP-1B in complex with a peptide inhibitor reveals an alternative binding mode for bisphosphonates.

Claude Dufresne, Yves Leblanc, E. Asante-Appiah, 2002, Biochemistry.

Discovery of potent and selective DP1 receptor antagonists in the azaindole series.

D. Denis, Y. Leblanc, G. O'neill, 2009, Bioorganic & medicinal chemistry letters.

Discovery of a potent and selective COX-2 inhibitor in the alkoxy lactone series with optimized metabolic profile.

D. Riendeau, P. Prasit, C. Brideau, 2002, Bioorganic & medicinal chemistry letters.

A New Series of Selective COX-2 Inhibitors: 5,6-Diarylthiazolo(3,2-b)( 1,2,4)triazoles.

P. Prasit, C. Brideau, C. Chan, 1997 .

The interaction of arginine 106 of human prostaglandin G/H synthase-2 with inhibitors is not a universal component of inhibition mediated by nonsteroidal anti-inflammatory drugs.

C. Bayly, J. Falgueyret, M. Percival, 1997, Molecular pharmacology.

Synthesis and reactions of pyrrolo[2,1-c][1,2,4]benzotriazine and 4-oxo-4H-pyrrolo[2,1-c][1,4]benzoxazine

G. V. Boyd, P. Roy, C. Turner, 1971 .