A. Sampson

发表

FLAP inhibitors for the treatment of inflammatory diseases.

A. Sampson, 2009, Current opinion in investigational drugs.

Variant LTC4 synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast

I. Sayers, P. Howarth, S. Holgate, 2000, Thorax.

Variation in preparation for gastroscopy: lessons towards safer and better outcomes

P. Boger, P. Patel, A. Sampson, 2016, Frontline Gastroenterology.

The HLA-DPB1*0301 marker might predict the requirement for leukotriene receptor antagonist in patients with aspirin-intolerant asthma.

Choon-Sik Park, Hae‐Sim Park, Seung-Hyun Kim, 2004, The Journal of allergy and clinical immunology.

Expression of 5‐lipoxygenase and cyclooxygenase pathway enzymes in nasal polyps of patients with aspirin‐intolerant asthma

K. Austen, B. Lam, J. Penrose, 2006, The Journal of pathology.

Increased expression of the 5‐lipoxygenase pathway and its cellular localization in Barrett’s adenocarcinoma

Susan J Wilson, A. Bateman, J. Holloway, 2012, Histopathology.

39 – Antihistamines and allergic disease

A. Sampson, D. Waller, 2018 .

9 – Cerebrovascular disease and dementia

A. Sampson, D. Waller, 2018 .

The immune response and immunosuppressant drugs

A. Sampson, D. Waller, 2018 .

Resolvin E1, resolvin D1 and resolvin D2 inhibit constriction of rat thoracic aorta and human pulmonary artery induced by the thromboxane mimetic U46619

J. Warner, C. Torrens, A. Sampson, 2018, British journal of pharmacology.

1 – Principles of pharmacology and mechanisms of drug action

A. Sampson, D. Waller, 2018 .

Cysteinyl leukotrienes synergize with growth factors to induce proliferation of human bronchial fibroblasts.

S. Holgate, D. Davies, E. Healy, 2007, The Journal of allergy and clinical immunology.

n‐3 polyunsaturated fatty acid supplementation, monocyte adhesion molecule expression and pro‐inflammatory mediators in Type 2 diabetes mellitus

M. Sampson, D. Hughes, A. Sampson, 2001, Diabetic medicine : a journal of the British Diabetic Association.

51 – Chemotherapy of infections

A. Sampson, D. Waller, 2018 .

Promoter polymorphism influences the effect of dexamethasone on transcriptional activation of the LTC4 synthase gene

I. Sayers, S. Holgate, S. Ye, 2003, European Journal of Human Genetics.

Will the Advent of Antileukotriene Therapy Lead to Changes in Asthma Treatment Guidelines?

S. Holgate, J. Corne, A. Sampson, 1997, BioDrugs.

Profound overexpression of leukotriene C4 synthase in bronchial biopsies from aspirin-intolerant asthmatic patients.

S. Holgate, K. Austen, K. Sladek, 1997, International archives of allergy and immunology.

CysLTR1 promoter polymorphism and requirement for leukotriene receptor antagonist in aspirin-intolerant asthma patients.

G. Hur, Hyun-Young Lee, Y. Ye, 2007, Pharmacogenomics.

Antileukotriene therapy. Future directions.

S. Holgate, A. Sampson, 2000, American journal of respiratory and critical care medicine.

IL-5 increases expression of 5-lipoxygenase-activating protein and translocates 5-lipoxygenase to the nucleus in human blood eosinophils.

S. Holgate, A. Cowburn, A. Sampson, 1999, Journal of immunology.

Colonic expression of leukotriene‐pathway enzymes in inflammatory bowel diseases

Penny A. Johnson, A. Bateman, J. Jupp, 2007, Inflammatory bowel diseases.

leukotrienes after acute asthma . Persistent increase in plasma and urinary

C. P. Green, A. Sampson, J. Price, 2006 .

Persistent increase in plasma and urinary leukotrienes after acute asthma.

C. P. Green, A. Sampson, J. Price, 1995, Archives of disease in childhood.

Antileukotrienes in Asthma and Rhinitis

A. Sampson, 2009 .

The anti-inflammatory effects of leukotriene-modifying drugs and their use in asthma.

S. Salvi, S. Holgate, M. Krishna, 2001, Chest.

Leukotriene and prostanoid pathway enzymes in bronchial biopsies of seasonal allergic asthmatics.

S. Holgate, K. Austen, J. Penrose, 2001, American journal of respiratory and critical care medicine.

Eosinophils: provokers or bystanders in asthma?

A. Sampson, 2001 .

Effect of intravenous corticosteroid on ex vivo leukotriene generation by blood leucocytes of normal and asthmatic patients

A. Sampson, J. Costello, P. P. Hood, 1999, Thorax.

Effects of cysteinyl leukotrienes and leukotriene receptor antagonists on markers of inflammation.

H. Bisgaard, E. Pizzichini, A. Sampson, 2003, The Journal of allergy and clinical immunology.

Cysteinyl leukotriene interactions with other mediators and with glucocorticosteroids during airway inflammation.

M. Peters-Golden, A. Sampson, 2003, The Journal of allergy and clinical immunology.

The effect of inhaled leukotriene B4 in normal and in asthmatic subjects.

A. Sampson, J. Costello, A. Sampson, 1997, American journal of respiratory and critical care medicine.

Effect of inhaled prostaglandin D2 in normal and atopic subjects, and of pretreatment with leukotriene D4.

A. Sampson, J. Costello, S. Sampson, 1997, Thorax.

Nasal mucosal expression of the leukotriene and prostanoid pathways in seasonal and perennial allergic rhinitis

P. Howarth, J. Penrose, A. Sampson, 2009, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

The leukotrienes: mediators of chronic inflammation in asthma

A. Sampson, 1996, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Are cysteinyl leukotrienes involved in allergic responses in human skin?

T. J. Griffiths, A. Cowburn, G. Clough, 2002, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

IL‐5 priming of eosinophil function in asthma

A. Sampson, 2001, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Human bronchial epithelial cells express an active and inducible biosynthetic pathway for leukotrienes B4 and C4

I. Sayers, P. Lackie, J. Penrose, 2007, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

The role of eosinophils and neutrophils in inflammation.

A. Sampson, Anthony P. Sampson, 2000, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

ASTHMA | Aspirin-Intolerant

A. Sampson, 2006 .

Interleukin-13, but Not Indomethacin, Increases Cysteinyl-Leukotriene Synthesis in Human Lung Macrophages

J. Warner, J. Holloway, A. Sampson, 2011, Journal of allergy.

A Tale of Two CysLTs

A. Sampson, A. J. James, 2001, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Effects of leukotrienes C4 and D4 on human isolated saphenous veins.

M. Yacoub, A. Chester, A. Sampson, 1992, British journal of clinical pharmacology.

Leukotrienes in cardiovascular disease

A. Sampson, A P Sampson, 2001 .

Developments in the field of allergy in 2011 through the eyes of Clinical and Experimental Allergy

A. Wardlaw, S. H. Arshad, S. Dharmage, 2012, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Assessment of in vivo 5-lipoxygenase activity by analysis of leukotriene B4 in saliva: effects of treatment with zileuton.

S. Dahlén, B. Dahlén, M. Kumlin, 2007, The Journal of allergy and clinical immunology.

Exposure to systemic prednisolone for 4 hours reduces ex vivo synthesis of GM‐CSF by bronchoalveolar lavage cells and blood mononuclear cells of mild allergic asthmatics

A. Sampson, J. Costello, P. P. Hood, 1999, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Role of cysteinyl leukotrienes in adenosine 5`-monophosphate induced bronchoconstriction in asthma

S. Holgate, S. Jennison, H. Arshad, 2002, Thorax.

Enhanced excretion of urinary leukotriene E4 in coronary artery disease and after coronary artery bypass surgery

M. Yacoub, A. Chester, S. Ohri, 1993, Coronary artery disease.

Human bronchial fibroblasts express the 5-lipoxygenase pathway

S. Holgate, J. Penrose, A. James, 2006, Respiratory research.

Reduction in leukotriene B4 generation by bronchoalveolar lavage cells in asthma.

L. Restrick, A. Sampson, P. Piper, 1995, Thorax.

Leukotrienes in the sputum and urine of cystic fibrosis children.

C. P. Green, A. Sampson, J. Price, 1990, British journal of clinical pharmacology.

Enhanced leukotriene synthesis in leukocytes of atopic and asthmatic subjects.

A. Sampson, P. Piper, J. Costello, 1992, British journal of clinical pharmacology.

The generation and metabolism of leukotrienes in the ionophore-stimulated blood of normal and asthmatic subjects.

A. Sampson, P. Piper, J. Costello, 1990, Pulmonary pharmacology.

The biotransformation in vitro of cysteinyl leukotrienes in blood of normal and asthmatic subjects.

J. Zakrzewski, N. Barnes, A. Sampson, 1989, Prostaglandins.

Leukotrienes Are Dispensable for Vaginal Neutrophil Recruitment as Part of the Immunopathological Response During Experimental Vulvovaginal Candidiasis

F. Wormley, A. Sampson, P. Fidel, 2021, Frontiers in Microbiology.

Leukotrienes and Inflammatory Lung Disease

C. P. Green, J. Price, A. Sampson, 1991, Annals of the New York Academy of Sciences.

Specific immunoglobulin E for staphylococcal enterotoxins in nasal polyps from patients with aspirin‐intolerant asthma

H. Kim, C. Suh, Seung-Hyun Kim, 2004, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

ASPIRIN-INTOLERANT ASTHMA : NEW INSIGHTS FROM BRONCHIAL MUCOSAL BIOPSIES

A. Sampson, 1998 .

Leukotriene antagonists and synthesis inhibitors: new directions in asthma therapy.

S T Holgate, S. Holgate, P. Bradding, 1996, The Journal of allergy and clinical immunology.

Leukotriene C4 synthase: the engine of aspirin intolerance?

A. Sampson, 2011, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

The metabolism "in vitro" of leukotriene B4 in blood of normal subjects and asthmatic patients.

J. Zakrzewski, N. Barnes, A. Sampson, 1988, Prostaglandins.

Molecular mechanisms of the synergy between cysteinyl-leukotrienes and receptor tyrosine kinase growth factors on human bronchial fibroblast proliferation

S. Holgate, D. Davies, A. Sampson, 2006, European Respiratory Review.

Leukotriene C4 Synthase Gene Polymorphism in Severe Asthma

I. Sayers, P. Howarth, S. Holgate, 2001 .

ff ect of inhaled prostaglandin D 2 in normal and atopic subjects , and of pretreatment with leukotriene D 4

A. Sampson, J. Costello, S. Sampson, 1998 .

Activity of the leukotriene pathway in Barrett’s metaplasia and oesophageal adenocarcinoma

P. Boger, P. Patel, A. Sampson, 2012, Inflammation Research.

Inulin as a marker of dilution of bronchoalveolar lavage in asthmatic and normal subjects.

L. Restrick, A. Sampson, P. Piper, 1995, American journal of respiratory and critical care medicine.

Aspirin Exacerbated Respiratory Disease

S. Holgate, L. Teran, Hae‐Sim Park, 2012, Journal of allergy.

Promoter polymorphism in the 5‐lipoxygenase (ALOX5) and 5‐lipoxygenase‐activating protein (ALOX5AP) genes and asthma susceptibility in a Caucasian population

I. Sayers, B. Beghé, S. Holgate, 2003, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

The cysteinyl‐leukotriene type 1 receptor polymorphism 927T/C is associated with atopy severity but not with asthma

I. Sayers, B. Beghé, S. Holgate, 2006, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma.

S. Holgate, K. Sladek, B. Lam, 1998, The Journal of clinical investigation.

OTHER NEUROLOGICAL DISORDERS

A. Sampson, D. Waller, 1965, Developmental medicine and child neurology.

Effects of celecoxib augmentation of antidepressant or anxiolytic treatment on affective symptoms and inflammatory markers in patients with anxiety disorders: exploratory study

D. Baldwin, A. Sampson, Hesham Y Elnazer, 2021, International clinical psychopharmacology.

Mast cell derived mediators

S. Holgate, J. Shute, M. Church, 1998 .

CYCLO-OXYGENASE. AUTHOR'S REPLY

S. Holgate, K. Austen, M. Belvisi, 1998 .

New therapeutic indications for Cys‐LT1 antagonists: atopic dermatitis and urticaria

G. Clough, M. Church, P. Friedmann, 2001 .

CysLT1 antagonists in the treatment of atopic dermatitis and urticaria

G. Clough, M. Church, P. Friedmann, 2001 .

Combination therapy with anti‐mediator drugs in allergic disease

S. Rorke, A. Sampson, 2001, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Lithium and sexual dysfunction: an under‐researched area

D. Baldwin, A. Sampson, Hesham Y. Elnazer, 2015, Human psychopharmacology.

Inhaled corticosteroids and long acting β2 agonists can help patients with COPD

I. Sayers, P. van Eerdewegh, B. Beghé, 2003, Thorax.

MK886 Reduces Cerebral Amyloid Angiopathy Severity in TgCRND8 Mice

R. Carare, J. McLaurin, C. Hawkes, 2013, Neurodegenerative Diseases.

Signaling in Mast Cells

M. Church, A. Sampson, 1998 .

Rhinovirus infection increases 5-lipoxygenase and cyclooxygenase-2 in bronchial biopsy specimens from nonatopic subjects.

S. Johnston, S. Holgate, J. Penrose, 2002, The Journal of infectious diseases.

Leukotrienes in the cardiovascular system.

A. Sampson, P. Piper, H. Yaacob, 1988, Advances in prostaglandin, thromboxane, and leukotriene research.

Anti-Inflammatory Drugs in Asthma

M. Church, A. Sampson, 1999, Progress in Inflammation Research.