M. Rafestin-Oblin

发表

Crucial role of the H11-H12 loop in stabilizing the active conformation of the human mineralocorticoid receptor.

D. Moras, J. Wurtz, D Moras, 2000, Molecular endocrinology.

Mineralocorticosteroid receptor of the chick intestine. Oligomeric structure and transformation.

E. Baulieu, M. Lombès, C. Radanyi, 1989, The Journal of biological chemistry.

Statistical test of models and computerised parameter estimation for aldosterone binding in rat kidney

A. Venot, J. Boisvieux, A. Mallet, 1978 .

Ligand-induced conformational change in the human mineralocorticoid receptor occurs within its hetero-oligomeric structure.

M. Lombès, J. Fagart, A. Souque, 1996, The Biochemical journal.

Antagonism in the human mineralocorticoid receptor

D. Moras, J. Wurtz, C. Hellal-Levy, 1998, The EMBO journal.

Corticosteroid-dependent sodium transport in a novel immortalized mouse collecting duct principal cell line.

A. Kahn, B. Rossier, A. Vandewalle, 1999, Journal of the American Society of Nephrology : JASN.

Dehydroepiandrosterone and its 7-hydroxylated metabolites do not interfere with the transactivation and cellular trafficking of the glucocorticoid receptor

M. Rafestin-Oblin, F. Cluzeaud, R. Morfin, 2004, The Journal of Steroid Biochemistry and Molecular Biology.

Phenotypic effects of aldosterone and dexamethasone in a SV40‐transformed mammalian cortical ascending limb cell line exhibiting mineralocorticoid receptors

A. Vandewalle, R. Cassingena, J. Hagège, 1993, Journal of cellular physiology.

Folding requirements of the ligand-binding domain of the human mineralocorticoid receptor.

C. Hellal-Levy, J. Fagart, M. Rafestin-Oblin, 1998, Molecular endocrinology.

Steroid profiling in preeclamptic women: evidence for aromatase deficiency.

M. Schumacher, N. Berkane, N. Chabbert-Buffet, 2010, American journal of obstetrics and gynecology.

Aldosterone Activates NF- (cid:1) B in the Collecting Duct

M. Vinciguerra, U. Hasler, M. Rafestin-Oblin, 2008 .

The mineralocorticoid receptor discriminates aldosterone from glucocorticoids independently of the 11ß-hydroxysteroid dehydrogenase

N. Farman, M. Lombès, J. Funder, 1995, Journal of endocrinological investigation.

The mineralocorticoid receptor discriminates aldosterone from glucocorticoids independently of the 11 beta-hydroxysteroid dehydrogenase.

N. Farman, M. Lombès, A. Souque, 1994, Endocrinology.

Spironolactone, an aldosterone antagonist, acts as an antiglucocorticosteroid on the mouse mammary tumor virus promoter.

E. Baulieu, H. Richard-Foy, M. Rafestin-Oblin, 1992, Endocrinology.

Conditional gene expression in renal collecting duct epithelial cells: use of the inducible Cre-lox system.

N. Farman, F. Jaisser, M. Blot-Chabaud, 2004, American journal of physiology. Renal physiology.

A Structural Explanation of the Effects of Dissociated Glucocorticoids on Glucocorticoid Receptor Transactivation

T. Idziorek, D. Hétuin, J. Fagart, 2014, Molecular Pharmacology.

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T. Idziorek, D. Hétuin, J. Fagart, 2013 .

Binding and antimineralocorticoid activities of spirolactones in toad bladder.

K. Geering, P. Corvol, B. Rossier, 1983, The American journal of physiology.

A new strategy for selective targeting of progesterone receptor with passive antagonists.

M. Lombès, N. Chabbert-Buffet, G. Meduri, 2013, Molecular endocrinology.

11-deoxycorticosterone is a potent agonist of the rainbow trout (Oncorhynchus mykiss) mineralocorticoid receptor.

G. Flouriot, P. Prunet, N. Bury, 2005, Endocrinology.

Affinity of corticosteroids for mineralocorticoid and glucocorticoid receptors of the rabbit kidney: effect of steroid substitution.

M. Lombès, P. Lustenberger, A. Michaud, 1986, Journal of steroid biochemistry.

Aldosterone binding in the human colon carcinoma cell line HT29: correlation with cell differentiation.

M. Lombès, A. Michaud, M. Rafestin-Oblin, 1984, Journal of steroid biochemistry.

Mineralocorticoid receptor mutations and a severe recessive pseudohypoaldosteronism type 1.

X. Jeunemaître, M. Zennaro, F. Fernandes-Rosa, 2011, Journal of the American Society of Nephrology : JASN.

Effects of thyroid hormones and aldosterone on mineralocorticoid binding sites in the toad bladder

K. Geering, B. Rossier, M. Rafestin-Oblin, 2005, Journal of Membrane Biology.

Molecular determinants of the recognition of ulipristal acetate by oxo-steroid receptors

J. Fagart, M. Rafestin-Oblin, A. Ulmann, 2014, The Journal of Steroid Biochemistry and Molecular Biology.

Aldosterone activates NF-kappaB in the collecting duct.

M. Vinciguerra, S. de Seigneux, U. Hasler, 2009, Journal of the American Society of Nephrology : JASN.

Dramatic protective effect of ligand against thermal degradation on mineraloand glucocorticoid receptors of rat kidney.

P. Corvol, A. Michaud, M. Rafestin-Oblin, 1977, Journal of steroid biochemistry.

Mechanism of action of a new antialdosterone compound, prorenone.

P. Corvol, A. Michaud, M. Rafestin-Oblin, 1979, Endocrinology.

Photoaffinity labelling of the human mineralocorticoid receptor with steroids having a reactive group at position 3, 18 or 21.

J. Fagart, A. Souque, M. Rafestin-Oblin, 1998, Biochimica et biophysica acta.

Structure-activity relationships of steroids with mineralocorticoid activity

G. Grassy, J. Fagart, M. Rafestin-Oblin, 1997 .

The mineralocorticoid activity of progesterone derivatives depends on the nature of the C18 substituent.

J. Fagart, A. Souque, M. Rafestin-Oblin, 1995, Endocrinology.

The establishment of the long terminal repeat of the mouse mammary tumor virus into CV-1 cells allows a functional analysis of steroid receptors.

H. Richard-Foy, D. Fortin, M. Rafestin-Oblin, 1994, Biochimica et biophysica acta.

Evidence for two distinct functional glucocorticoid receptors in teleost fish.

V. Laudet, P. Prunet, Y. Guiguen, 2003, Journal of molecular endocrinology.

Mineralocorticoid receptors during normal kidney growth and compensatory renal hypertrophy.

P. Corvol, A. Michaud, M. Rafestin-Oblin, 1981, Journal of steroid biochemistry.

Multiple aspects of mineralocorticoid selectivity.

N. Farman, M. Rafestin-Oblin, 2001, American journal of physiology. Renal physiology.

Mechanistic aspects of mineralocorticoid receptor activation.

C. Hellal-Levy, J. Fagart, A. Souque, 2000, Kidney international.

The Met852 Residue Is a Key Organizer of the Ligand-Binding Cavity of the Human Mineralocorticoid Receptor

J. Fagart, M. Rafestin-Oblin, C. Seguin, 2005, Molecular Pharmacology.

Mineralocorticoid receptors in the epithelial cells of human colon and ileum.

M. Lombès, A. Michaud, M. Rafestin-Oblin, 1984, Journal of steroid biochemistry.

Structural determinants of ligand binding to the mineralocorticoid receptor

J. Fagart, M. Rafestin-Oblin, M. Fay, 2012, Molecular and Cellular Endocrinology.

Cell-specific, promoter-dependent mineralocorticoid agonist activity of spironolactone.

R. Barouki, M. Lombès, C. Massaad, 1997, Molecular pharmacology.

A single amino acid mutation of ala-773 in the mineralocorticoid receptor confers agonist properties to 11beta-substituted spirolactones.

D. Moras, J. Wurtz, C. Hellal-Levy, 2000, Molecular pharmacology.

A Single Amino Acid Mutation of Ala-773 in the Mineralocorticoid Receptor Confers Agonist Properties to 11 b -Substituted Spirolactones

D. Moras, J. Wurtz, C. Hellal-Levy, 2000 .

Identification of steroid ligands able to inactivate the mineralocorticoid receptor harboring the S810L mutation responsible for a severe form of hypertension

A. Vandewalle, J. Fagart, A. Souque, 2004, Molecular and Cellular Endocrinology.

A new affinity matrix for mineralocorticoid receptors.

M. Lombès, P. Lustenberger, A. Michaud, 1987, The Journal of biological chemistry.

Specific hydroxylations determine selective corticosteroid recognition by human glucocorticoid and mineralocorticoid receptors

C. Gomez-Sanchez, C. Hellal-Levy, J. Fagart, 1999, FEBS letters.

Spirolactones: clinical and pharmacologic studies.

J. Ménard, P. Corvol, A. Michaud, 1977, Advances in nephrology from the Necker Hospital.

Finerenone Impedes Aldosterone-dependent Nuclear Import of the Mineralocorticoid Receptor and Prevents Genomic Recruitment of Steroid Receptor Coactivator-1*

M. Lombès, S. Viengchareun, A. Hillisch, 2015, The Journal of Biological Chemistry.

Structural Basis of Spirolactone Recognition by the Mineralocorticoid Receptor

Jessica Huyet, Marie-Edith Rafestin-Oblin, J. Fagart, 2007, Molecular Pharmacology.

11β-Hydroxyprogesterone Acts as a Mineralocorticoid Agonist in Stimulating Na+ Absorption in Mammalian Principal Cortical Collecting Duct Cells

A. Vandewalle, M. Bens, J. Fagart, 2002 .

Are receptor-associated nuclear proteins associated with the earliest effects of steroid hormones?

J. Garnier, E. Baulieu, F. Cadepond, 1990, Revista espanola de fisiologia.

Differential intracellular localization of human mineralocorticosteroid receptor on binding of agonists and antagonists.

E. Baulieu, M. Lombès, N. Binart, 1994, The Biochemical journal.

Characterization of human mineralocorticosteroid receptor expressed in the baculovirus system.

E. Baulieu, M. Lombès, N. Binart, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Nestorone® as a Novel Progestin for Nonoral Contraception: Structure-Activity Relationships and Brain Metabolism Studies

M. Schumacher, J. Lambert, P. Liere, 2017, Endocrinology.

The severe form of hypertension caused by the activating S810L mutation in the mineralocorticoid receptor is cortisone related.

A. Vandewalle, J. Fagart, A. Souque, 2003, Endocrinology.

A New Mode of Mineralocorticoid Receptor Antagonism by a Potent and Selective Nonsteroidal Molecule*

Alexander Hillisch, Stefan Schäfer, E. Pook, 2010, The Journal of Biological Chemistry.

The Synthetic Androgen Methyltrienolone (R1881) Acts as a Potent Antagonist of the Mineralocorticoid Receptor

A. Vandewalle, M. Bens, J. Fagart, 2007, Molecular Pharmacology.

Tritiated 9α-fluorocortisol metabolism and binding in rat kidney

P. Corvol, A. Michaud, M. Rafestin-Oblin, 1977, Steroids.

Sulfhydryl groups are involved in the binding of agonists and antagonists to the human mineralocorticoid receptor

J. Fagart, A. Souque, M. Rafestin-Oblin, 1996, The Journal of Steroid Biochemistry and Molecular Biology.

11beta-hydroxyprogesterone acts as a mineralocorticoid agonist in stimulating Na+ absorption in mammalian principal cortical collecting duct cells.

A. Vandewalle, M. Bens, J. Fagart, 2002, Molecular pharmacology.

Aldosterone antagonists destabilize the mineralocorticosteroid receptor.

E. Baulieu, M. Lombès, M. Rafestin-Oblin, 1992, The Biochemical journal.

Differences between aldosterone and its antagonists in binding kinetics and ligand-induced hsp90 release from mineralocorticosteroid receptor

E. Baulieu, M. Lombès, M. Rafestin-Oblin, 1992, The Journal of Steroid Biochemistry and Molecular Biology.

Mineralocorticoid receptors in SV40-transformed tubule cell lines derived from rabbit kidney

N. Farman, A. Vandewalle, R. Cassingena, 1993, Journal of Steroid Biochemistry and Molecular Biology.

Modulation of aldosterone receptors in rat kidney: effects of steroid treatment and potassium diet.

M. Lombès, P. Corvol, A. Michaud, 1984, Journal of steroid biochemistry.

Crystal structure of a mutant mineralocorticoid receptor responsible for hypertension

Claudine Mayer, C. Mayer, M. Rochel, 2005, Nature Structural &Molecular Biology.

Conformational Change in the Human Glucocorticoid Receptor Induced by Ligand Binding Is Altered by Mutation of Isoleucine 747 by a Threonine*

J. Nicolas, M. Rafestin-Oblin, B. Couette, 1999, The Journal of Biological Chemistry.

Met909 Plays a Key Role in the Activation of the Progesterone Receptor and Also in the High Potency of 13-Ethyl Progestins

J. Fagart, M. Rafestin-Oblin, A. Ulmann, 2009, Molecular Pharmacology.

Mineralocorticoid receptor mutations differentially affect individual gene expression profiles in pseudohypoaldosteronism type 1.

X. Jeunemaître, N. Tchitchek, M. Zennaro, 2011, The Journal of clinical endocrinology and metabolism.

Glucocorticoid metabolism by 11-β hydroxysteroid dehydrogenase type 2 modulates human mineralocorticoid receptor transactivation activity

N. Farman, J. Fagart, M. Rafestin-Oblin, 2003, The Journal of Steroid Biochemistry and Molecular Biology.

Cross-reactivity of a monoclonal antiglucocorticoid receptor antibody BuGR1 with glucocorticoid and mineralocorticoid receptors of various species.

R. Harrison, M. Lombès, M. Rafestin-Oblin, 1986, Journal of steroid biochemistry.