B. Refouvelet

发表

Synthesis, structure, and estrogenic activity of 4-amino-3-(2-methylbenzyl)coumarins on human breast carcinoma cells.

G. Leclercq, Y. Jacquot, G. Laurent, 2007, Bioorganic & medicinal chemistry.

Dihydrothienopsoralens: New furocoumarins as potential photoreacting agents

F. Aubin, B. Refouvelet, A. Xicluna, 1999 .

Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease

Simone Brogi, K. Nikolić, D. Agbaba, 2017, Progress in Neurobiology.

The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators.

Oscar M. Bautista-Aguilera, D. Jun, R. León, 2016, Journal of medicinal chemistry.

Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer’s disease therapy

K. Musílek, Ignacio Moraleda, I. Iriepa, 2019, Journal of enzyme inhibition and medicinal chemistry.

5-amino salicylic acid bound nanoparticles for the therapy of inflammatory bowel disease.

A. Lamprecht, D. Neumann, A. Nadaradjane, 2007, Journal of controlled release : official journal of the Controlled Release Society.

3-Aminoacetylthiazolidine-4-carboxylate esters and their l-thia-4-azaspiro[4.5]decane-3-carboxylate derivatives. Synthesis and stereochemical properties

J. Rouland, B. Refouvelet, B. Bachet, 1997 .

Anticonvulsant activity of 3-oxo-5-substituted benzylidene-6-methyl-(4H)-2-pyridazinylacetamides and 2-pyridazinylacetylhydrazides.

B. Refouvelet, J. Bastide, P. Coudert, 1990, Chemical & pharmaceutical bulletin.

Donepezil-ferulic acid hybrids as anti-Alzheimer drugs.

T. Gharbi, J. Marco-Contelles, M. Pudlo, 2015, Future medicinal chemistry.

Pharmacophore Modelling and Synthesis of Quinoline-3-Carbohydrazide as Antioxidants

M. Pudlo, B. Refouvelet, L. Ismaili, 2011, International journal of medicinal chemistry.

Synthesis of new ferulic/lipoic/comenic acid-melatonin hybrids as antioxidants and Nrf2 activators via Ugi reaction.

J. Marco-Contelles, H. Martin, B. Refouvelet, 2019, Future medicinal chemistry.

Synthesis of Hantzsch Adducts as Cholinesterases and Calcium Flux inhibitors, Antioxidants and Neuroprotectives

Ignacio Moraleda, I. Iriepa, J. Marco-Contelles, 2020, International journal of molecular sciences.

Multicomponent reactions as a privileged tool for multitarget-directed ligand strategies in Alzheimer's disease therapy.

B. Refouvelet, S. Grosjean, L. Ismaili, 2022, Future medicinal chemistry.

Synthesis of 4-hydroxycoumarin and 2,4-quinolinediol derivatives and evaluation of their effects on the viability of HepG2 cells and human hepatocytes culture.

Y. Jacquot, G. Mantion, B. Refouvelet, 2004, European journal of medicinal chemistry.

Synthesis and antioxidant activity evaluation of new hexahydropyrimido[5,4-c]quinoline-2,5-diones and 2-thioxohexahydropyrimido[5,4-c]quinoline-5-ones obtained by Biginelli reaction in two steps.

A. Nadaradjane, B. Refouvelet, A. Xicluna, 2008, European journal of medicinal chemistry.

Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer’s disease therapy

D. Jun, O. Soukup, Ignacio Moraleda, 2018, Journal of enzyme inhibition and medicinal chemistry.

New Dipeptides Containing Thiazolidine-4-carboxylic Acid Derivatives : Synthesis and Characterization Using NMR Techniques and X-Ray Data

G. Crini, O. Blacque, B. Refouvelet, 1999 .

Synthesis, biological assessment and molecular modeling of new dihydroquinoline-3-carboxamides and dihydroquinoline-3-carbohydrazide derivatives as cholinesterase inhibitors, and Ca channel antagonists.

Abdelouahid Samadi, E. Soriano, J. Marco-Contelles, 2011, European journal of medicinal chemistry.

Synthesis and Antioxidant Activity Evaluation of New Hexahydropyrimido[5,4‐c]quinoline‐2,5‐diones and 2‐Thioxohexahydropyrimido[5,4‐c]quinoline‐5‐ones Obtained by Biginelli Reaction in Two Steps.

A. Nadaradjane, B. Refouvelet, A. Xicluna, 2008 .

Recent advances in the development of phytoestrogens and derivatives: an update of the promising perspectives in the prevention of postmenopausal diseases.

Y. Jacquot, G. Leclercq, B. Refouvelet, 2003, Mini reviews in medicinal chemistry.

Pharmacological profile of 6,12-dihydro-3-methoxy-1-benzopyrano[3,4-b] [1,4]benzothiazin-6-one, a novel human estrogen receptor agonist.

G. Leclercq, Y. Jacquot, G. Adessi, 2002, Biological & pharmaceutical bulletin.

An efficient two-step synthesis of 4-methyl-1,2,3,5,6,10b -hexahydropyrimido [5,4 -C ]quinoline -2,5-diones via biginelli reaction

B. Refouvelet, A. Xicluna, L. Ismaili, 2007 .

Substituted benzopyranobenzothiazinones. Synthesis and estrogenic activity on MCF-7 breast carcinoma cells.

Y. Jacquot, G. Adessi, L. Bermont, 2001, European journal of medicinal chemistry.

(±)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease.

E. M. García-Frutos, V. Andrisano, M. Bartolini, 2021, ACS chemical neuroscience.

Design, Synthesis and Biological Evaluation of New Antioxidant and Neuroprotective Multitarget Directed Ligands Able to Block Calcium Channels

J. Marco-Contelles, H. Martin, B. Refouvelet, 2020, Molecules.

Synthesis, regioselectivity, and DFT analysis of new antioxidant pyrazolo[4,3-c]quinoline-3,4-diones

Oscar M. Bautista-Aguilera, T. Gharbi, G. Herlem, 2016, Monatshefte für Chemie - Chemical Monthly.

Synthesis and stereochemical studies of 2-substituted thiazolidine-4-carboxamide derivatives

G. Crini, O. Blacque, B. Refouvelet, 2000 .

Thiazolidine-2,4-dicarboxylic acid and its esters : synthesis, in solution behaviour and regioselective cyclocondensation

B. Refouvelet, J. Robert, J. Couquelet, 1994 .

Behaviour of coumarin in chloride bath: Relationship with coumarin influence on zinc electrodeposition

P. Berçot, M. Mouanga, L. Ricq, 2007 .

Chromatographic Determination of the Association Constants Between Psoralen Derivatives and Modified β‐Cyclodextrin: Effect of Sucrose as a Co‐enhancer Association Agent

Y. Guillaume, S. Makki, J. Millet, 2003 .

Phloroglucinol: novel synthesis and role of the magnesium cation on its binding with human serum albumin (HSA) using a biochromatographic approach based on Langmuir isotherms.

Y. Guillaume, B. Refouvelet, A. Xicluna, 2003, Journal of pharmaceutical and biomedical analysis.

Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer’s Disease Therapy

Oscar M. Bautista-Aguilera, F. López-Muñoz, K. Musílek, 2020, International journal of molecular sciences.

A novel cyclic hexapeptide as chiral selector: Application for HPLC separation of a series of dansyl amino and arylalkanoic acids.

Y. Guillaume, C. André, B. Refouvelet, 2007, Talanta.

Quinolone-benzylpiperidine derivatives as novel acetylcholinesterase inhibitor and antioxidant hybrids for Alzheimer disease.

M. Pudlo, B. Refouvelet, V. Luzet, 2014, Bioorganic & medicinal chemistry.

Synthesis and Biological Evaluation of Novel Chromone+Donepezil Hybrids for Alzheimer's Disease Therapy.

K. Musílek, I. Iriepa, J. Marco-Contelles, 2019, Current Alzheimer research.

Novel Tacrine‐Grafted Ugi Adducts as Multipotent Anti‐Alzheimer Drugs: A Synthetic Renewal in Tacrine–Ferulic Acid Hybrids

V. Andrisano, M. Bartolini, M. Bolognesi, 2015, ChemMedChem.

Anticonvulsant Activity of 3-Oxo-5-Substituted Benzylidene-6-methyl-( 4H)-2-pyridazinylacetamides and 2-Pyridazinylacetylhydrazides.

B. Refouvelet, J. Bastide, P. Coudert, 1991 .

Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer’s Disease Treatment

I. Iriepa, J. Marco-Contelles, R. Cornu, 2023, International journal of molecular sciences.

Structure elucidation of benzopyran-2-ol in solution and in solid state following the reduction of coumarin by DIBAL-H

Y. Jacquot, O. Blacque, B. Refouvelet, 2001 .

Discovery of New Highly Potent Histamine H3 Receptor Antagonists, Calcium Channel Blockers, and Acetylcholinesterase Inhibitors.

T. Karcz, K. Kieć‐Kononowicz, I. Iriepa, 2024, ACS chemical neuroscience.