Rajalekshmy Shyam

发表

Processing of Optineurin in Neuronal Cells*

Y. Qiu, B. Yue, T. Iwata, 2010, The Journal of Biological Chemistry.

Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease

Binxing Li, Paul S. Bernstein, P. Bernstein, 2016, Progress in Retinal and Eye Research.

Wnt gene expression in human trabecular meshwork cells

B. Yue, Xiang Shen, Rajalekshmy Shyam, 2010, Molecular vision.

Impairment of Protein Trafficking upon Overexpression and Mutation of Optineurin

Y. Qiu, B. Yue, Xiang Shen, 2010, PloS one.

Ammonia sensitive SLC4A11 mitochondrial uncoupling reduces glutamine induced oxidative stress

Rajalekshmy Shyam, J. Bonanno, Moonjung Choi, 2019, Redox biology.

Effects of mutations and deletions in the human optineurin gene

B. Yue, Xiang Shen, Hongyu Ying, 2014, SpringerPlus.

Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth.

Y. Qiu, B. Yue, Xiang Shen, 2010, The American journal of pathology.

MitoROS due to loss of Slc4a11 in corneal endothelial cells induces ER stress, lysosomal dysfunction and impairs autophagy

Rajalekshmy Shyam, J. Bonanno, Moonjung Choi, 2020, bioRxiv.

Rescue of the Congenital Hereditary Endothelial Dystrophy Mouse Model by Adeno-Associated Virus–Mediated Slc4a11 Replacement

Rajalekshmy Shyam, J. Bonanno, Moonjung Choi, 2021, Ophthalmology science.

Rescue of the CHED Mouse Model by AAV-mediated Slc4a11 Replacement

Rajalekshmy Shyam, J. Bonanno, Moonjung Choi, 2021, Ophthalmology Science.

Mitochondrial ROS in Slc4a11 KO Corneal Endothelial Cells Lead to ER Stress

Rajalekshmy Shyam, J. Bonanno, D. Ogando, 2022, Frontiers in Cell and Developmental Biology.

Bicarbonate activates glycolysis and lactate production in corneal endothelial cells by increased pHi.

Rajalekshmy Shyam, J. Bonanno, D. Ogando, 2020, Experimental eye research.

Mitochondrial ROS Induced Lysosomal Dysfunction and Autophagy Impairment in an Animal Model of Congenital Hereditary Endothelial Dystrophy

P. Liton, Rajalekshmy Shyam, J. Bonanno, 2021, Investigative ophthalmology & visual science.

Inducible Slc4a11 Knockout Triggers Corneal Edema Through Perturbation of Corneal Endothelial Pump

Chia-Yang Liu, Rajalekshmy Shyam, J. Bonanno, 2021, Investigative ophthalmology & visual science.

RPE65 has an additional function as the lutein to meso-zeaxanthin isomerase in the vertebrate eye

P. Bernstein, Rajalekshmy Shyam, M. Horvath, 2017, Proceedings of the National Academy of Sciences.

AUTOPHAGY IN THE EYE: FROM PHYSIOLOGY TO PATHOPHYSOLOGY.

G. Laurie, P. Boya, M. Boulton, 2023, Autophagy reports.

Cellular Processing of Myocilin

Y. Qiu, B. Yue, Xiang Shen, 2014, PloS one.

All three human scavenger receptor class B proteins can bind and transport all three macular xanthophyll carotenoids.

P. Bernstein, Rajalekshmy Shyam, Aruna Gorusupudi, 2017, Archives of biochemistry and biophysics.

Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease

P. Bernstein, J. Nolan, Binxing Li, 2016, Progress in Retinal and Eye Research.