R. Castino

发表

Guidelines for the use and interpretation of assays for monitoring autophagy

Robert Clarke, Hong Jiang, Hiroyuki Ishida, 2012 .

Cathepsin D released by lactating rat mammary epithelial cells is involved in prolactin cleavage under physiological conditions

C. Isidoro, M. Lkhider, M. Ollivier-Bousquet, 2004, Journal of Cell Science.

Autophagy is a prosurvival mechanism in cells expressing an autosomal dominant familial neurohypophyseal diabetes insipidus mutant vasopressin transgene

David Murphy, J. Davies, C. Isidoro, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Akt Induces Apoptosis in Neuroblastoma Cells Expressing a C98X Vasopressin Mutant Following Autophagy Suppression

C. Isidoro, C. Thepparit, D. Murphy, 2008, Journal of neuroendocrinology.

Preconditioning-induced cytoprotection in hepatocytes requires Ca2+-dependent exocytosis of lysosomes

C. Isidoro, M. Démoz, E. Albano, 2004, Journal of Cell Science.

Chelation of lysosomal iron protects dopaminergic SH-SY5Y neuroblastoma cells from hydrogen peroxide toxicity by precluding autophagy and Akt dephosphorylation.

Antonino Giovia, C. Isidoro, R. Castino, 2011, Toxicological sciences : an official journal of the Society of Toxicology.

The transport of soluble lysosomal hydrolases from the Golgi complex to lysosomes

C. Isidoro, R. Castino, 2008 .

Suppression of autophagy precipitates neuronal cell death following low doses of methamphetamine

G. Lazzeri, F. Fornai, P. Lenzi, 2008, Journal of neurochemistry.

Inhibition of PI3k class III-dependent autophagy prevents apoptosis and necrosis by oxidative stress in dopaminergic neuroblastoma cells.

Carlo Follo, C. Isidoro, D. Murphy, 2010, Toxicological sciences : an official journal of the Society of Toxicology.

Differential role of cathepsins B and L in autophagy-associated cell death induced by arsenic trioxide in U87 human glioblastoma cells

C. Isidoro, R. Castino, T. Lah, 2010, Biological chemistry.

Transformation by oncogenic ras‐p21 alters the processing and subcellular localization of the lysosomal protease cathepsin D

C. Isidoro, M. Démoz, R. Castino, 1999, Journal of cellular biochemistry.

Resveratrol reduces the invasive growth and promotes the acquisition of a long-lasting differentiated phenotype in human glioblastoma cells.

C. Isidoro, R. Castino, T. Lah, 2011, Journal of agricultural and food chemistry.

Destination ‘Lysosome’: a target organelle for tumour cell killing?

C. Isidoro, M. Démoz, R. Castino, 2003, Journal of molecular recognition : JMR.

Endosomal-Lysosomal Proteolysis Mediates Death Signalling by TNFα, Not by Etoposide, in L929 Fibrosarcoma Cells: Evidence for an Active Role of Cathepsin D

C. Isidoro, M. Démoz, P. Cesaro, 2002, Biological chemistry.

cFLIP expression correlates with tumour progression and patient outcome in non‐Hodgkin lymphomas of low grade of malignancy

C. Isidoro, G. Nicosia, R. Castino, 2006, British journal of haematology.

Expression of protein kinase C β1 confers resistance to TNFα‐ and paclitaxel‐induced apoptosis in HT‐29 colon carcinoma cells

C. Isidoro, M. Démoz, P. Cesaro, 2001 .

Lysosomal proteases as potential targets for the induction of apoptotic cell death in human neuroblastomas

C. Isidoro, M. Démoz, R. Castino, 2002, International journal of cancer.

Knock-Down of Cathepsin D Affects the Retinal Pigment Epithelium, Impairs Swim-Bladder Ontogenesis and Causes Premature Death in Zebrafish

Carlo Follo, C. Isidoro, M. Santoro, 2011, PloS one.

Folding, activity and targeting of mutated human cathepsin D that cannot be processed into the double-chain form.

Carlo Follo, C. Isidoro, R. Castino, 2007, The international journal of biochemistry & cell biology.

The lysosomal protease cathepsin D is efficiently sorted to and secreted from regulated secretory compartments in the rat basophilic/mast cell line RBL.

A. Luini, C. Isidoro, M. Démoz, 2000, Journal of cell science.

DNA damage response by single-strand breaks in terminally differentiated muscle cells and the control of muscle integrity

M. Crescenzi, E. Dogliotti, C. Isidoro, 2012, Cell Death and Differentiation.

High yield synthesis and characterization of phosphorylated recombinant human procathepsin D expressed in mammalian cells.

Bonnie F. Sloane, Carlo Follo, C. Isidoro, 2006, Protein expression and purification.

High Expression of Cathepsin D in Non-Hodgkin’s Lymphomas Negatively Impacts on Clinical Outcome

Carlo Follo, C. Isidoro, N. Fusco, 2010, Disease markers.

KNOCK-DOWN OF CATHEPSIN D AFFECTS THE RETINAL PIGMENT EPITHELIUM, IMPAIRS SWIM-BLADDER ONTOGENESIS AND CAUSES TO PRAECOX DEATH IN ZEBRAFISH / Carlo Follo;

Carlo Follo, C. Isidoro, M. Santoro, 2022 .

PI3K-dependent lysosome exocytosis in nitric oxide-preconditioned hepatocytes.

C. Isidoro, E. Albano, R. Castino, 2006, Free radical biology & medicine.

Lysosomal segregation of a mannose‐rich glycoprotein imparted by the prosequence of myeloperoxidase

C. Isidoro, A. Hasilik, N. Harth, 1998, Journal of cellular biochemistry.

Cathepsin D-Bax death pathway in oxidative stressed neuroblastoma cells.

Carlo Follo, C. Isidoro, R. Castino, 2007, Free radical biology & medicine.

Expression of protein kinase C beta1 confers resistance to TNFalpha- and paclitaxel-induced apoptosis in HT-29 colon carcinoma cells.

C. Isidoro, M. Démoz, P. Cesaro, 2001, International journal of cancer.

Chemotherapy drug response in ovarian cancer cells strictly depends on a cathepsin D-Bax activation loop

C. Isidoro, M. Démoz, R. Castino, 2008, Journal of cellular and molecular medicine.

The expression of prolactin and its cathepsin D-mediated cleavage in the bovine corpus luteum vary with the estrous cycle.

J. Martial, F. Gaunitz, C. Isidoro, 2007, American journal of physiology. Endocrinology and metabolism.

Patented Biomarkers for the Early Detection of Ovarian Cancer

C. Isidoro, R. Castino, R. Veneroni, 2011 .

Co-Expression of Plexin-B1 and Met in Human Breast and Ovary Tumours Enhances the Risk of Progression

C. Isidoro, M. Prat, L. Tamagnone, 2009, Cellular oncology : the official journal of the International Society for Cellular Oncology.

Autophagy-active beclin-1 correlates with favourable clinical outcome in non-Hodgkin lymphomas

Carlo Follo, C. Isidoro, R. Castino, 2010, Modern Pathology.

Resveratrol-induced apoptosis depends on the lipid kinase activity of Vps34 and on the formation of autophagolysosomes.

Carlo Follo, C. Isidoro, R. Castino, 2008, Carcinogenesis.

Autophagy‐dependent cell survival and cell death in an autosomal dominant familial neurohypophyseal diabetes insipidus in vitro model

C. Isidoro, D. Murphy, R. Castino, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Resveratrol induces cell death in colorectal cancer cells by a novel pathway involving lysosomal cathepsin D.

Carlo Follo, C. Isidoro, R. Castino, 2006, Carcinogenesis.

Rorschach records of Nazi war criminals: a reanalysis using current scoring and interpretation practices.

E. Zillmer, R. Archer, R. Castino, 1989, Journal of personality assessment.

Inhibition of Autophagy In Vivo Extends Methamphetamine Toxicity to Mesencephalic Cell Bodies

F. Biagioni, L. Ryskalin, A. Frati, 2021, Pharmaceuticals.

The dilemma: does tissue expression of cathepsin D reflect tumor malignancy? The question: does the assay truly mirror cathepsin D mis-function in the tumor?

Carlo Follo, C. Isidoro, R. Castino, 2010, Cancer biomarkers : section A of Disease markers.

Contextual effects in duration experience.

D J Bobko, D. J. Bobko, H. Schiffman, 1977, The American journal of psychology.

Guidelines for the use and interpretation of assays for monitoring autophage

T. P. Neufeld, Thomas J. Begley, H. Coller, 2012 .

Prolactin promotes the secretion of active cathepsin D at the basal side of rat mammary acini.

C. Isidoro, M. Démoz, M. Ollivier-Bousquet, 2008, Endocrinology.

Chelation of lysosomal iron protects dopaminergic SH-SY5Y neuroblastoma cells from hydrogen peroxide toxicity by precluding autophagy and Akt dephosphorylation.

Antonino Giovia, C. Isidoro, R. Castino, 2011, Toxicological sciences : an official journal of the Society of Toxicology.