K. Facchine

发表

A Detailed Study of Sulfonate Ester Formation and Solvolysis Reaction Rates and Application toward Establishing Sulfonate Ester Control in Pharmaceutical Manufacturing Processes

Patrick Sandra, Andrew Teasdale, Frank David, 2010 .

Chemical Mechanism of the Covalent Modification of 5.alpha.-Reductases by Finasteride as Probed by Secondary Tritium Isotope Effects

K. Facchine, Shiang-yuan Chen, G. Tian, 1995 .

Separation and identification of retinoic acid photo-isomers

A. Oyler, D. J. Burinsky, K. Facchine, 1989 .

Available guidance and best practices for conducting force degradation studies

Dan W. Reynolds, Kevin L. Facchine, June F. Mullaney, 2002 .

The utility of sulfonate salts in drug development.

Patrick Sandra, Andrew Teasdale, Frank David, 2010, Journal of pharmaceutical sciences.

Characterization of autoxidation products of the antifungal compounds econazole nitrate and miconazole nitrate

A. Oyler, D. J. Burinsky, K. Facchine, 1991 .

Characterization of Autoxidation Products of the Antifungal Compounds Econazole Nitrate and Miconazole Nitrate.

A. Oyler, D. J. Burinsky, K. Facchine, 1991 .

Characterizationf of autoxidation products of retinoic acid

A. Oyler, D. J. Burinsky, K. Facchine, 1989 .

Mechanism and Processing Parameters Affecting the Formation of Methyl Methanesulfonate from Methanol and Methanesulfonic Acid: An Illustrative Example for Sulfonate Ester Impurity Formation

Patrick Sandra, Andrew Teasdale, Frank David, 2009 .

Simultaneous quantitation of trace level hydrazine and acetohydrazide in pharmaceuticals by benzaldehyde derivatization with sample 'matrix matching' followed by liquid chromatography-mass spectrometry.

David Q. Liu, David Q Liu, K. Facchine, 2016, Journal of chromatography. A.

The Degradation Chemistry of Farglitazar and Elucidation of the Oxidative Degradation Mechanisms.

K. Facchine, I. Paulus, T. M. O'Connell, 2017, Journal of pharmaceutical sciences.

An Approach to Control Strategies for Sulfonate Ester Formation in Pharmaceutical Manufacturing Based on Recent Scientific Understanding

D. Elder, R. L. Parsons, A. Teasdale, 2012 .

An improved HPLC assay for the assessment of liver slice metabolic viability using 7-ethoxycoumarin.

J. Walsh, K. Facchine, K. Halm, 1995, Drug metabolism and disposition: the biological fate of chemicals.

Analysis of unstable degradation impurities of a benzodiazepine and their quantification without isolation using multiple linear regression

B. Igne, K. Facchine, Jacalyn S. Clawson, 2019, Journal of pharmaceutical and biomedical analysis.

Elucidating the pathways of degradation of denagliptin.

D. E. Patterson, R. Copley, K. Facchine, 2010, Journal of pharmaceutical sciences.