Michal Douša

发表

Direct analysis in real time--high resolution mass spectrometry as a valuable tool for the pharmaceutical drug development.

B. Klejdus, P. Stasiak, L. Nováková, 2014, Talanta.

Development of HPLC Method for the Purity Test by Design of Experiments and Determination of Activation Energy of Hydrolytic Degradation Reactions of Sofosbuvir

P. Řezanka, Michal Douša, J. Petřík, 2020 .

Quality by Design as a risk-based strategy in pharmaceutical analysis: Development of a liquid chromatography-tandem mass spectrometry method for the determination of nintedanib and its impurities.

R. Gotti, S. Furlanetto, S. Orlandini, 2020, Journal of chromatography. A.

Enantioseparation and impurity determination of ambrisentan using cyclodextrin-modified micellar electrokinetic chromatography: Visualizing the design space within quality by design framework.

S. Furlanetto, S. Pinzauti, S. Orlandini, 2016, Journal of chromatography. A.

Effect of Chromatographic Conditions on Enantioseparation of Bedaquiline Using Polysaccharide-based Chiral Stationary Phases in RP-HPLC.

Michal Douša, Josef Reitmajer, M. Štefko, 2016, Journal of chromatographic science.

General screening and optimization strategy for fast chiral separations in modern supercritical fluid chromatography.

L. Nováková, Michal Douša, 2017, Analytica chimica acta.

Fundamental study of enantioselective HPLC separation of tapentadol enantiomers using cellulose-based chiral stationary phase in normal phase mode.

Michal Douša, Z. Bosáková, P. Lehnert, 2013, Journal of pharmaceutical and biomedical analysis.

Enantiomeric Separation of (R,S)-Aclidinium Bromide with Negatively Charged Gamma-Cyclodextrin by CE

Michal Douša, Z. Bosáková, Hana Adamusová, 2017, Chromatographia.

HPLC/UV/MS method application for the separation of obeticholic acid and its related compounds in development process and quality control

Michal Douša, T. Kubelka, J. Zezula, 2018, Journal of pharmaceutical and biomedical analysis.

Optimization of o-phtaldialdehyde/2-mercaptoethanol postcolumn reaction for the hydrophilic interaction liquid chromatography determination of memantine utilizing a silica hydride stationary phase.

D. Sýkora, Michal Douša, Veronika Pivoňková, 2016, Journal of separation science.

Underivatized amylose and cellulose as new stationary phases for hydrophilic interaction chromatography.

K. Lemr, Michal Douša, P. Lehnert, 2013, Journal of separation science.

Chiral separation of aliphatic primary amino alcohols as o-phthaldialdehyde/mercaptoethanol derivatives on polysaccharide-based chiral stationary phases.

Michal Douša, 2019, Chirality.

Enantioseparation of N‐acetyl‐DL‐cysteine as o‐phtaldialdehyde derivatives obtained with various primary aliphatic amine additives on polysaccharide‐based chiral stationary phases

Michal Douša, 2019, Journal of pharmaceutical and biomedical analysis.

Quantification of 2‐aminoisobutyric acid impurity in enzalutamide bulk drug substance using hydrophilic interaction chromatography with fluorescence detection

Michal Douša, 2019, Journal of pharmaceutical and biomedical analysis.

The determination of pharmaceutically active thiols using hydrophilic interaction chromatography followed postcolumn derivatization with o‐phthaldialdehyde and fluorescence detection

Michal Douša, 2018, Journal of pharmaceutical and biomedical analysis.

Quantification of structurally related aliphatic amino alcohols in l-valinol by hydrophilic interaction liquid chromatography separation combined with postcolumn derivatization and fluorescence detection.

K. Lemr, Michal Douša, Petr Gibala, 2016, Journal of separation science.

Rapid HILIC method with fluorescence detection using derivatization reaction utilizing o-phthaldialdehyde for determination of degradation product of aliskiren.

Michal Douša, Jiří Břicháč, Robert Klvaňa, 2012, Journal of pharmaceutical and biomedical analysis.

Rapid hydrophilic interaction chromatography determination of lysine in pharmaceutical preparations with fluorescence detection after postcolumn derivatization with o-phtaldialdehyde.

Michal Douša, Jiří Břicháč, P. Lehnert, 2011, Journal of pharmaceutical and biomedical analysis.

Liquid chromatographic separation of pregabalin and its possible impurities with fluorescence detection after postcolumn derivatization with o-phtaldialdehyde.

K. Lemr, Michal Douša, Petr Gibala, 2010, Journal of pharmaceutical and biomedical analysis.

Quality by Design-Guided Development of a Capillary Electrophoresis Method for the Chiral Purity Determination of Ambrisentan

G. Scriba, Michal Douša, Sulaiman Krait, 2016, Chromatographia.

HILIC-MS determination of dimethylamine in the active pharmaceutical ingredients and in the dosage forms of metformin.

Michal Douša, J. Jireš, 2020, Journal of pharmaceutical and biomedical analysis.

Identification, characterization, synthesis and HPLC quantification of new process-related impurities and degradation products in retigabine.

Michal Douša, Petr Gibala, Lucie Nováková, 2014, Journal of pharmaceutical and biomedical analysis.

Supercritical fluid chromatography in chiral separations: Evaluation of equivalency of polysaccharide stationary phases.

L. Nováková, Michal Douša, P. Jakubec, 2020, Journal of separation science.

Detection and structure elucidation of the new degradation impurities in the pharmaceutical formulations of ruxolitinib hydrobromide.

J. Doubský, Michal Douša, M. Tkadlecová, 2020, Journal of pharmaceutical and biomedical analysis.

Rapid determination of amoxicillin in premixes by HPLC.

Michal Douša, R. Hosmanová, 2005, Journal of pharmaceutical and biomedical analysis.

Chiral capillary zone electrophoresis in enantioseparation and analysis of cinacalcet impurities: Use of Quality by Design principles in method development.

R. Gotti, S. Furlanetto, S. Orlandini, 2018, Journal of chromatography. A.

Enantiomeric separation of tapentadol by capillary electrophoresis--study of chiral selectivity manipulation by various types of cyclodextrins.

S. Béni, J. Znaleziona, V. Maier, 2015, Journal of pharmaceutical and biomedical analysis.

Enantiomeric purity control of R-cinacalcet in pharmaceutical product by capillary electrophoresis

J. Znaleziona, Jan Petr, R. Knob, 2016, Chemical Papers.

The formation of furfural compounds in selected saccharide- and polysaccharide-based pharmaceutical excipients.

J. Havlíček, Michal Douša, Jiří Břicháč, 2012, Journal of pharmaceutical sciences.

Separation of structurally related primary aliphatic amines using hydrophilic interaction chromatography with fluorescence detection after postcolumn derivatization with o-phthaldialdehyde/mercaptoethanol.

Michal Douša, Jan Doubský, J. Doubský, 2017, Journal of separation science.

Identification and structure elucidation of a new degradation impurity in the multi‐component tablets of amlodipine besylate

Michal Douša, Jiří Břicháč, M. Štefko, 2019, Journal of pharmaceutical and biomedical analysis.

Drug-excipient compatibility testing-Identification and characterization of degradation products of phenylephrine in several pharmaceutical formulations against the common cold.

Michal Douša, Petr Gibala, J. Havlíček, 2011, Journal of pharmaceutical and biomedical analysis.

Development, validation and comparison of UHPSFC and UHPLC methods for the determination of agomelatine and its impurities.

Michal Douša, Lucie Nováková, L. Nováková, 2016, Journal of pharmaceutical and biomedical analysis.

Analytical quality by design in the development of a solvent-modified micellar electrokinetic chromatography method for the determination of sitagliptin and its related compounds.

R. Gotti, S. Furlanetto, S. Orlandini, 2021, Journal of pharmaceutical and biomedical analysis.

1H-Tetrazole-5-amine Immobilized on Substituted Polymer Gel/Silica as a New Stationary Phase for Hydrophilic Interaction Chromatography

Michal Douša, 2018, Chromatographia.

A novel approach for HPLC determination of 2-cynaoacetamide using derivatization procedure with 2-hydroxyacetophenone as a new useful derivatization reagent.

J. Hájíček, Michal Douša, Jiří Břicháč, 2016, Journal of pharmaceutical and biomedical analysis.

Retention behavior of a homologous series and positional isomers of aliphatic amino acids in hydrophilic interaction chromatography.

L. Nováková, J. Srbek, Michal Douša, 2014, Journal of separation science.

Insight into the formation of N-nitrosodimethylamine in metformin products.

P. Řezanka, J. Rudovský, Michal Douša, 2020, Journal of pharmaceutical and biomedical analysis.

New approach of validation using internal normalization technique for quantification of related substances in raw material, intermediates and pharmaceutical substances by HPLC.

Michal Douša, T. Pekárek, Petr Gibala, 2015, Journal of pharmaceutical and biomedical analysis.

N-Nitrosation in the absence of nitrosating agents in pharmaceuticals?

Michal Douša, T. Kubelka, Petr Gibala, 2022, Journal of Pharmaceutical and Biomedical Analysis.

Esterification of Ibuprofen in Soft Gelatin Capsules Formulations-Identification, Synthesis and Liquid Chromatography Separation of the Degradation Products.

J. Srbek, Michal Douša, Jiří Břicháč, 2017, Journal of chromatographic science.

HILIC-MS Determination of Genotoxic Impurity of 2-Chloro-N-(2-Chloroethyl)Ethanamine in the Vortioxetine Manufacturing Process.

Michal Douša, Jan Doubský, Petr Gibala, 2015, Journal of chromatographic science.

Identification, preparation and UHPLC determination of process-related impurity in zolmitriptan.

Zuzana Mandelová, Michal Douša, Jiří Břicháč, 2012, Journal of pharmaceutical and biomedical analysis.

HPLC determination of lincomycin in premixes and feedstuffs with solid-phase extraction on HLB OASIS and LC-MS/MS confirmation.

K. Lemr, Michal Douša, M. Halama, 2006, Journal of pharmaceutical and biomedical analysis.

Utilization of Photochemically Induced Fluorescence Detection for HPLC Determination of Genotoxic Impurities in the Vortioxetine Manufacturing Process.

J. Doubský, J. Srbek, Michal Douša, 2016, Journal of chromatographic science.

Nitrites as precursors of N-nitrosation in pharmaceutical samples - A trace level analysis.

Michal Douša, J. Jireš, 2022, Journal of pharmaceutical and biomedical analysis.

HPLC/UV/MS method application for the separation of obeticholic acid and its related compounds in development process and quality control

Michal Douša, T. Kubelka, J. Zezula, 2018, Journal of pharmaceutical and biomedical analysis.

What is the role of current mass spectrometry in pharmaceutical analysis?

L. Nováková, Michal Douša, R. Kučera, 2023, Mass spectrometry reviews.

Development, validation and comparison of UHPSFC and UHPLC methods for the determination of agomelatine and its impurities.

L. Nováková, Michal Douša, Lucia Chrenková, 2016, Journal of pharmaceutical and biomedical analysis.

Analytical Quality by Design-Compliant Development of a Cyclodextrin-Modified Micellar ElectroKinetic Chromatography Method for the Determination of Trimecaine and Its Impurities

R. Gotti, S. Furlanetto, S. Orlandini, 2023, Molecules.