O. Ghribi

发表

Molecular events linking cholesterol to Alzheimer's disease and inclusion body myositis in a rabbit model.

Brandon Smith, D. L. Zhang, Q. Liu, 2016, American journal of neurodegenerative disease.

Caffeine protects against disruptions of the blood-brain barrier in animal models of Alzheimer's and Parkinson's diseases.

J. Geiger, O. Ghribi, Xuesong Chen, 2010, Journal of Alzheimer's disease : JAD.

Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina

Brij B. Singh, O. Ghribi, B. Dasari, 2011, BMC ophthalmology.

27-hydroxycholesterol: A novel player in molecular carcinogenesis of breast and prostate cancer.

Shaneabbas Raza, O. Ghribi, Gurdeep Marwarha, 2017, Chemistry and physics of lipids.

The role of the endoplasmic reticulum in the accumulation of beta-amyloid peptide in Alzheimer's disease.

O. Ghribi, 2006, Current molecular medicine.

Potential mechanisms linking cholesterol to Alzheimer's disease-like pathology in rabbit brain, hippocampal organotypic slices, and skeletal muscle.

O. Ghribi, 2008, Journal of Alzheimer's disease : JAD.

Leptin reduces the accumulation of Abeta and phosphorylated tau induced by 27-hydroxycholesterol in rabbit organotypic slices.

O. Ghribi, B. Dasari, J. Prasanthi, 2010, Journal of Alzheimer's disease : JAD.

The Rabbit Model System for Studies of Aluminum-Induced Neurofibrillary Degeneration: Relevance to Human Neurodegenerative Disorders

M. Herman, M. Forbes, O. Ghribi, 2001 .

Palmitate-induced Endoplasmic Reticulum stress and subsequent C/EBPα Homologous Protein activation attenuates leptin and Insulin-like growth factor 1 expression in the brain.

O. Ghribi, Gurdeep Marwarha, Jared Schommer, 2016, Cellular signalling.

Palmitate‐induced C/EBP homologous protein activation leads to NF‐κB‐mediated increase in BACE1 activity and amyloid beta genesis

O. Ghribi, Gurdeep Marwarha, Jared Schommer, 2018, Journal of neurochemistry.

GDNF regulates the Aβ-induced endoplasmic reticulum stress response in rabbit hippocampus by inhibiting the activation of gadd 153 and the JNK and ERK kinases

M. Herman, P. Pramoonjago, O. Ghribi, 2004, Neurobiology of Disease.

Palmitic Acid-Enriched Diet Increases α-Synuclein and Tyrosine Hydroxylase Expression Levels in the Mouse Brain

O. Ghribi, Gurdeep Marwarha, K. Nagamoto-Combs, 2018, Front. Neurosci..

Oxidative stress in blood in Alzheimer's disease and mild cognitive impairment: A meta-analysis

G. Perry, R. Squitti, M. Schrag, 2013, Neurobiology of Disease.

Differential effects of 24‐hydroxycholesterol and 27‐hydroxycholesterol on tyrosine hydroxylase and α‐synuclein in human neuroblastoma SH‐SY5Y cells

O. Ghribi, A. Thompson, Jaya Prasanthi Rantham Prabhakara, 2008, Journal of neurochemistry.

Endoplasmic reticulum stress-induced CHOP activation mediates the down-regulation of leptin in human neuroblastoma SH-SY5Y cells treated with the oxysterol 27-hydroxycholesterol.

O. Ghribi, B. Dasari, Gurdeep Marwarha, 2012, Cellular signalling.

Targeted glycomics by selected reaction monitoring for highly sensitive glycan compositional analysis

Jianjun Li, J. Geiger, Q. Liu, 2012, Proteomics.

A Diet Enriched in Palmitate and Deficient in Linoleate Exacerbates Oxidative Stress and Amyloid-β Burden in the Hippocampus of 3xTg-AD Mouse Model of Alzheimer's Disease.

O. Ghribi, Gurdeep Marwarha, Jared Schommer, 2019, Journal of Alzheimer's disease : JAD.

Peri-nuclear clustering of mitochondria is triggered during aluminum maltolate induced apoptosis.

K. Griffioen, O. Ghribi, J. Savory, 2006, Journal of Alzheimer's Disease.

Aluminum maltolate-induced toxicity in NT2 cells occurs through apoptosis and includes cytochrome c release.

K. Griffioen, O. Ghribi, J. Savory, 2004, Neurotoxicology.

Intracellular mechanisms underlying aluminum-induced apoptosis in rabbit brain.

M. Herman, O. Ghribi, J. Savory, 2003, Journal of inorganic biochemistry.

Regulation of β-amyloid levels in the brain of cholesterol-fed rabbit, a model system for sporadic Alzheimer’s disease

O. Ghribi, A. Thompson, Gwen Feist, 2008, Mechanisms of Ageing and Development.

Molecular interplay between leptin, insulin-like growth factor-1, and β-amyloid in organotypic slices from rabbit hippocampus

O. Ghribi, B. Dasari, J. Prasanthi, 2011, Molecular Neurodegeneration.

Lithium inhibits Aβ‐induced stress in endoplasmic reticulum of rabbit hippocampus but does not prevent oxidative damage and tau phosphorylation

M. Herman, O. Ghribi, J. Savory, 2003, Journal of neuroscience research.

The oxysterol 27-hydroxycholesterol increases β-amyloid and oxidative stress in retinal pigment epithelial cells

Brij B. Singh, O. Ghribi, B. Dasari, 2010, BMC Ophthalmology.

27-Hydroxycholesterol increases α-synuclein protein levels through proteasomal inhibition in human dopaminergic neurons

O. Ghribi, Gurdeep Marwarha, Jared Schommer, 2018, BMC Neuroscience.

Amelioration Effect ofEmblica officinalisExtract on Ovary in Endosulfan Induced Swiss Albino Mice

A. Nokhodchi, O. Ghribi, Xiong-hao Lin, 2016 .

MPP+ Induces the Endoplasmic Reticulum Stress Response in Rabbit Brain Involving Activation of the ATF‐6 and NF‐κB Signaling Pathways

M. Herman, P. Pramoonjago, O. Ghribi, 2003, Journal of neuropathology and experimental neurology.

The endoplasmic reticulum is the main site for caspase-3 activation following aluminum-induced neurotoxicity in rabbit hippocampus

M. Herman, O. Ghribi, J. Savory, 2002, Neuroscience Letters.

Broad DNA repair responses in neural injury are associated with activation of the IL‐6 pathway in cholesterol‐fed rabbits

Min Wu, O. Ghribi, R. Cochran, 2009, Journal of neurochemistry.

Impairment of synaptic transmission by transient hypoxia in hippocampal slices: improved recovery in glutathione peroxidase transgenic mice.

G. Massicotte, D. Furling, M. Mirault, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Preservation of the blood brain barrier integrity may underlie neuroprotective effects of statins in Alzheimer's disease.

O. Ghribi, 2006, Journal of Alzheimer's disease : JAD.

Maternal low-protein diet causes body weight loss in male, neonate Sprague-Dawley rats involving UCP-1-mediated thermogenesis.

J. Roemmich, T. Rhen, O. Ghribi, 2015, The Journal of nutritional biochemistry.

Ca nStudie so fAluminu mToxicit yIn Vivo an dIn Vitro Provid eRelevan tInformatio non the Pathogenesis and Etiology of Alzheimer's Disease?

O. Ghribi, J. Savory, 2007 .

Can studies of aluminum toxicity in vivo and in vitro provide relevant information on the pathogenesis and etiology of Alzheimer's disease?

O. Ghribi, J. Savory, 2007, Journal of Alzheimer's disease : JAD.

Hippocampus of Ames dwarf mice is resistant to β‐amyloid‐induced tau hyperphosphorylation and changes in apoptosis‐regulatory protein levels

M. Schrag, H. Brown-Borg, Sunita Sharma, 2008, Hippocampus.

Epigenetics of inflammation, maternal infection, and nutrition.

O. Ghribi, C. Brissette, K. Claycombe, 2015, The Journal of nutrition.

Mechanisms of aluminum-induced neurodegeneration in animals: Implications for Alzheimer's disease.

M. Herman, O. Ghribi, J. Savory, 2006, Journal of Alzheimer's disease : JAD.

Abeta(1-42) and aluminum induce stress in the endoplasmic reticulum in rabbit hippocampus, involving nuclear translocation of gadd 153 and NF-kappaB.

M. Herman, M. Forbes, O. Ghribi, 2001, Brain research. Molecular brain research.

Hypoxia‐Induced Loss of Synaptic Transmission Is Exacerbated in Hippocampal Slices of Transgenic Mice Expressing C‐Terminal Fragments of Alzheimer Amyloid Precursor Protein

M. Ohayon, G. Massicotte, J. Nalbantoglu, 1999, Hippocampus.

Hypercholesterolemia-induced Aβ accumulation in rabbit brain is associated with alteration in IGF-1 signaling

Sunita Sharma, O. Ghribi, Gwen Feist, 2008, Neurobiology of Disease.

Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation

Mason S Kleinjan, Jaclyn Lilek, O. Ghribi, 2017, Journal of Alzheimer's disease : JAD.

27-hydroxycholesterol decreases cell proliferation in colon cancer cell lines.

Jessica A Warns, O. Ghribi, Gurdeep Marwarha, 2018, Biochimie.

27-Hydroxycholesterol stimulates cell proliferation and resistance to docetaxel-induced apoptosis in prostate epithelial cells

B. Guo, O. Ghribi, Shaneabbas Raza, 2016, Medical Oncology.

The cholesterol metabolite 27-hydroxycholesterol regulates p53 activity and increases cell proliferation via MDM2 in breast cancer cells

J. Ohm, Archana Dhasarathy, O. Ghribi, 2015, Molecular and Cellular Biochemistry.

Method for organotypic tissue culture in the aged animal

M. Schrag, O. Ghribi, Gurdeep Marwarha, 2017, MethodsX.

The neuroprotective effect of fisetin in the MPTP model of Parkinson's disease.

O. Ghribi, K. Benzeroual, Mital Y Patel, 2012, Journal of Parkinson's disease.

Aluminum-induced dendritic pathology revisited: cytochemical and electron microscopic studies of rabbit cortical pyramidal neurons.

M. Herman, M. Forbes, O. Ghribi, 2002, Annals of clinical and laboratory science.

Aβ(1-42) and aluminum induce stress in the endoplasmic reticulum in rabbit hippocampus, involving nuclear translocation of gadd 153 and NF-κB

M. Herman, M. Forbes, O. Ghribi, 2001 .

Aluminium and neuronal cell injury: inter-relationships between neurofilamentous arrays and apoptosis.

M. Herman, M. Forbes, O. Ghribi, 2001, Journal of inorganic biochemistry.

Lithium inhibits aluminum‐induced apoptosis in rabbit hippocampus, by preventing cytochrome c translocation, Bcl‐2 decrease, Bax elevation and caspase‐3 activation

M. Herman, O. Ghribi, J. Savory, 2002, Journal of neurochemistry.

Leptin signaling and Alzheimer's disease.

O. Ghribi, Gurdeep Marwarha, 2012, American journal of neurodegenerative disease.

Deferiprone reduces amyloid-β and tau phosphorylation levels but not reactive oxygen species generation in hippocampus of rabbits fed a cholesterol-enriched diet.

M. Schrag, W. Kirsch, O. Ghribi, 2012, Journal of Alzheimer's disease : JAD.

Co-involvement of mitochondria and endoplasmic reticulum in regulation of apoptosis: changes in cytochrome c, Bcl-2 and Bax in the hippocampus of aluminum-treated rabbits

M. Herman, M. Forbes, O. Ghribi, 2001, Brain Research.

Cholesterol-enriched diet disrupts the blood-testis barrier in rabbits.

J. Geiger, O. Ghribi, Xuesong Chen, 2014, American journal of physiology. Endocrinology and metabolism.

β‐Amyloid regulates leptin expression and tau phosphorylation through the mTORC1 signaling pathway

O. Ghribi, B. Dasari, Gurdeep Marwarha, 2010, Journal of neurochemistry.

Caffeine protects against oxidative stress and Alzheimer's disease-like pathology in rabbit hippocampus induced by cholesterol-enriched diet.

J. Geiger, O. Ghribi, Xuesong Chen, 2010, Free radical biology & medicine.

The cholesterol metabolite 27-hydroxycholesterol stimulates cell proliferation via ERβ in prostate cancer cells

B. Guo, O. Ghribi, Shaneabbas Raza, 2017, Cancer Cell International.

Identification of microRNAs involved in Alzheimer's progression using a rabbit model of the disease.

Brandon Smith, Q. Liu, R. Koukiekolo, 2014, American journal of neurodegenerative disease.

GDNF Protects against Aluminum-Induced Apoptosis in Rabbits by Upregulating Bcl-2 and Bcl-XL and Inhibiting Mitochondrial Bax Translocation

M. Herman, M. Forbes, O. Ghribi, 2001, Neurobiology of Disease.

Does the oxysterol 27-hydroxycholesterol underlie Alzheimer's disease–Parkinson's disease overlap?

O. Ghribi, Gurdeep Marwarha, 2015, Experimental Gerontology.

Leptin attenuates BACE1 expression and amyloid-β genesis via the activation of SIRT1 signaling pathway.

O. Ghribi, Gurdeep Marwarha, Shaneabbas Raza, 2014, Biochimica et biophysica acta.

Leptin attenuates BACE 1 expression and amyloid-β genesis via the activation of SIRT 1 signaling pathway

O. Ghribi, Gurdeep Marwarha, Shaneabbas Raza, 2014 .

Silencing GADD153/CHOP Gene Expression Protects against Alzheimer's Disease-Like Pathology Induced by 27-Hydroxycholesterol in Rabbit Hippocampus

O. Ghribi, J. Prasanthi, Jared Schommer, 2011, PloS one.

Cellular model of Alzheimer's disease — Relevance to therapeutic testing

O. Ghribi, Gurdeep Marwarha, 2012, Experimental Neurology.

Abeta(1-42)-induced JNK and ERK activation in rabbit hippocampus is differentially regulated by lithium but is not involved in the phosphorylation of tau.

M. Herman, O. Ghribi, J. Savory, 2003, Brain research. Molecular brain research.

Endolysosome mechanisms associated with Alzheimer's disease-like pathology in rabbits ingesting cholesterol-enriched diet.

J. Geiger, O. Ghribi, Xuesong Chen, 2011, Journal of Alzheimer's disease : JAD.

Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease

J. Geiger, O. Ghribi, Xuesong Chen, 2008, Journal of Neuroinflammation.

Cellular hormetic response to 27-hydroxycholesterol promotes neuroprotection through AICD induction of MAST4 abundance and kinase activity

Christopher G. Wilson, Traci L. Marin, H. Vinters, 2017, Scientific Reports.

Cyclosporin A inhibits Al-induced cytochrome c release from mitochondria in aged rabbits.

M. Herman, M. Forbes, O. Ghribi, 2001, Journal of Alzheimer's disease : JAD.

Alpha-Synuclein-induced DNA Methylation and Gene Expression in Microglia

Brett A. McGregor, J. Hur, K. Guo, 2021, Neuroscience.

Supplementation of the diet with silicic acid to reduce body burden of aluminum: a miracle cure or useless treatment for Alzheimer's disease?

M. Herman, O. Ghribi, J. Savory, 2006, Journal of Alzheimer's disease : JAD.

Gadd153 and NF-κB Crosstalk Regulates 27-Hydroxycholesterol-Induced Increase in BACE1 and β-Amyloid Production in Human Neuroblastoma SH-SY5Y Cells

O. Ghribi, J. Prasanthi, Gurdeep Marwarha, 2013, PloS one.

High cholesterol content in neurons increases BACE, β-amyloid, and phosphorylated tau levels in rabbit hippocampus

M. Herman, M. Schrag, O. Ghribi, 2006, Experimental Neurology.

Maternal low-protein diet decreases brain-derived neurotrophic factor expression in the brains of the neonatal rat offspring.

O. Ghribi, Gurdeep Marwarha, Jared Schommer, 2017, The Journal of nutritional biochemistry.

Palmitate-Induced SREBP1 Expression and Activation Underlies the Increased BACE 1 Activity and Amyloid Beta Genesis

O. Ghribi, Gurdeep Marwarha, K. Claycombe-Larson, 2018, Molecular Neurobiology.

Metabolomic Identification in Cerebrospinal Fluid of the Effects of High Dietary Cholesterol in a Rabbit Model of Alzheimer’s Disease

J. Geiger, Q. Liu, O. Ghribi, 2012, Metabolomics : open access.

Deposition of iron and β‐amyloid plaques is associated with cortical cellular damage in rabbits fed with long‐term cholesterol‐enriched diets

M. Schrag, M. Golovko, O. Ghribi, 2006, Journal of neurochemistry.

Molecular Neurodegeneration Differential Effects of 24-hydroxycholesterol and 27-hydroxycholesterol on Β-amyloid Precursor Protein Levels and Processing in Human Neuroblastoma Sh-sy5y Cells

Prasanthi, O. Ghribi, J. Prasanthi, 2022 .

The oxysterol 27‐hydroxycholesterol regulates α‐synuclein and tyrosine hydroxylase expression levels in human neuroblastoma cells through modulation of liver X receptors and estrogen receptors–relevance to Parkinson’s disease

T. Rhen, O. Ghribi, Gurdeep Marwarha, 2011, Journal of neurochemistry.

Rabbits fed cholesterol-enriched diets exhibit pathological features of inclusion body myositis.

J. Geiger, O. Ghribi, Xuesong Chen, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

Cholinergic systems and long-term potentiation in memory-impaired apolipoprotein E-deficient mice

J. Poirier, G. Massicotte, S. Kar, 1999, Neuroscience.

Differential Effects of the Estrogen Receptor Agonist Estradiol on Toxicity Induced by Enzymatically-Derived or Autoxidation-Derived Oxysterols in Human ARPE-19 Cells

Brij B. Singh, O. Ghribi, B. Dasari, 2013, Current eye research.

Ovarian steroids and selective estrogen receptor modulators activity on rat brain NMDA and AMPA receptors

M. Cyr, M. Morissette, T. Paolo, 2001, Brain Research Reviews.

Is amyloid β-peptide neurotoxic or neuroprotective and what is its role in the binding of metal ions?

M. Herman, O. Ghribi, J. Savory, 2002, Neurobiology of Aging.

Competitive NMDA receptor blockers reduce striatal glutamate accumulation in ischaemia.

M. Plotkine, J. Callebert, O. Ghribi, 1994, Neuroreport.

Palmitate-Induced SREBP1 Expression and Activation Underlies the Increased BACE 1 Activity and Amyloid Beta Genesis

O. Ghribi, Gurdeep Marwarha, K. Claycombe-Larson, 2018, Molecular Neurobiology.

Abstract 5048: The cholesterol metabolite, 27-hydroxycholesterol stimulates cell proliferation in prostate epithelial cell lines via estrogen receptor beta

B. Guo, O. Ghribi, Shaneabbas Raza, 2015 .

Increased EID1 nuclear translocation impairs synaptic plasticity and memory function associated with pathogenesis of Alzheimer's disease

S. Lei, Q. Liu, O. Ghribi, 2012, Neurobiology of Disease.

Role of Endolysosomes in Skeletal Muscle Pathology Observed in a Cholesterol-Fed Rabbit Model of Alzheimer’s Disease

J. Geiger, O. Ghribi, Xuesong Chen, 2016, Front. Aging Neurosci..

Caffeine blocks cholesterol-enriched diet induced AD-like pathology in rabbits

J. Geiger, H. Tian, O. Ghribi, 2016 .

Elevated clozapine plasma concentrations after fluvoxamine initiation.

J. Desce, O. Ghribi, G. Dumortier, 1996, The American journal of psychiatry.

Folding Free-Energy Landscape of α-Synuclein (35-97) Via Replica Exchange Molecular Dynamics.

J. Delhommelle, O. Ghribi, Karnesh Jain, 2020, Journal of chemical information and modeling.

The cholesterol metabolite 27-hydroxycholesterol stimulates cell proliferation via ERβ in prostate cancer cells

B. Guo, O. Ghribi, Shaneabbas Raza, 2017, Cancer Cell International.

Alteration of glutamate receptors in the striatum of dyskinetic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys following dopamine agonist treatment

P. Blanchet, P. Bédard, F. Calon, 2002, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

LEPTIN ATTENUATES BACE1 EXPRESSION AND AMYLOID-B GENESIS VIA THE ACTIVATION OF SIRT1 SIGNALING PATHWAY

O. Ghribi, Gurdeep Marwarha, C. Meiers, 2014, Alzheimer's & Dementia.

Nuclear Factor Kappa-light-chain-enhancer of Activated B Cells (NF-κB) - a Friend, a Foe, or a Bystander - in the Neurodegenerative Cascade and Pathogenesis of Alzheimer's Disease.

O. Ghribi, Gurdeep Marwarha, 2017, CNS & neurological disorders drug targets.

AMPA receptor regulation and LTP in the hippocampus of young and aged apolipoprotein E-deficient mice

J. Poirier, G. Massicotte, O. Ghribi, 2001, Neurobiology of Aging.

Do Increased Levels of Oxysterols Underlie Alzheimer’s Disease/Parkinson’s Disease Overlap?

O. Ghribi, 2012 .

Inhibition of glutamate release in rat hippocampus by kynurenic acid does not protect CA1 cells from forebrain ischemia

M. Plotkine, J. Callebert, O. Ghribi, 1992, Brain Research.

Effect of kynurenic acid on the ischaemia-induced accumulation of glutamate in rat striatum.

M. Plotkine, J. Callebert, O. Ghribi, 1994, Neuroreport.

Blockers of NMDA‐operated channels decrease glutamate and aspartate extracellular accumulation in striatum during forebrain ischaemia in rats

M. Plotkine, J. Callebert, O. Ghribi, 1995, Fundamental & clinical pharmacology.

l-NAME modulates glutamate accumulation induced by K+-depolarization but not by forebrain ischaemia in the rat striatum

M. Plotkine, J. Callebert, O. Ghribi, 1994, Neuroscience Letters.