Y. Nakao

发表

In Vivo Gold Complex Catalysis within Live Mice.

H. Onoe, Yasuyoshi Watanabe, Katsunori Tanaka, 2017, Angewandte Chemie.

Effect of mycalolides isolated from a marine sponge Mycale aff. nullarosette on actin in living cells

H. Kimura, Yoko Hayashi-Takanaka, R. V. Soest, 2019, Scientific Reports.

Insights on pregnane-X-receptor modulation. Natural and semisynthetic steroids from Theonella marine sponges.

E. Novellino, V. Sepe, A. Zampella, 2014, European journal of medicinal chemistry.

Kakeromamide A, a new cyclic pentapeptide inducing astrocyte differentiation isolated from the marine cyanobacterium Moorea bouillonii.

Young‐Tae Chang, M. Kawamura, N. Fusetani, 2018, Bioorganic & medicinal chemistry letters.

Preliminary Structure-Activity Relationship on Theonellasterol, a New Chemotype of FXR Antagonist, from the Marine Sponge Theonella swinhoei

G. Bifulco, V. Sepe, A. Zampella, 2012, Marine drugs.

Evaluation of antiangiogenic activity of azumamides by the in vitro vascular organization model using mouse induced pluripotent stem (iPS) cells.

Minoru Yoshida, Satoko Maeda, J. Yamashita, 2008, Bioorganic & medicinal chemistry letters.

Gracilioethers A-C, antimalarial metabolites from the marine sponge Agelas gracilis.

R. Ueoka, R. V. van Soest, S. Matsunaga, 2009, The Journal of organic chemistry.

Piceatannol is superior to resveratrol in promoting neural stem cell differentiation into astrocytes.

M. Kawamura, Y. Nakao, Satoshi Otsuka, 2016, Food & function.

Efficient route to RIKEN click probes for glycoconjugation

Katsunori Tanaka, Kazuki Tsubokura, Y. Nakao, 2019, Journal of Carbohydrate Chemistry.

Cancer cell targeting driven by selective polyamine reactivity with glycine propargyl esters.

Katsunori Tanaka, S. Noguchi, N. Taniguchi, 2017, Chemical communications.

A new antiangiogenic C24 oxylipin from the soft coral Sinularia numerosa.

S. Matsunaga, Yukimitsu Imahara, N. Fusetani, 2009, Bioorganic & medicinal chemistry.

Disrupting tumor onset and growth via selective cell tagging (SeCT) therapy

H. Onoe, Yasuyoshi Watanabe, Katsunori Tanaka, 2021, Science Advances.

In vivo metal-catalyzed SeCT therapy by a proapoptotic peptide

Katsunori Tanaka, Takehiro Suzuki, N. Dohmae, 2021, Chemical science.

A Genetically Encoded FRET Probe to Detect Intranucleosomal Histone H3K9 or H3K14 Acetylation Using BRD4, a BET Family Member.

Minoru Yoshida, A. Ito, Y. Nakao, 2016, ACS chemical biology.

Kulokekahilide-2, a cytotoxic depsipeptide from a cephalaspidean mollusk Philinopsis speciosa.

P. Scheuer, S. Mooberry, Y. Nakao, 2004, Journal of natural products.

Spectomycin B1 as a novel SUMOylation inhibitor that directly binds to SUMO E2.

Kam Y. J. Zhang, K. Shin‐ya, Ashutosh Kumar, 2013, ACS chemical biology.

Spectomycin B 1 as a Novel SUMOylation Inhibitor That Directly Binds to SUMO E 2

Kam Y. J. Zhang, K. Shin‐ya, Ashutosh Kumar, 2013 .

One-Pot Evolution of Ageladine A through a Bio-Inspired Cascade towards Selective Modulators of Neuronal Differentiation.

Katsunori Tanaka, K. Fukase, Kazuki Tsubokura, 2016, Chemistry.

Epigenetic Effects of Exposure to Insecticide on Early Differentiation of Mouse Embryonic Stem Cells

J. Ohgane, H. Sone, K. Abe, 2019, bioRxiv.

Cultivation of previously uncultured sponge-associated bacteria using advanced cultivation techniques: A perspective on possible key mechanisms

T. Kindaichi, Y. Aoi, A. Ohashi, 2022, Frontiers in Marine Science.

Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells.

H. Aburatani, K. Shin‐ya, T. Umehara, 2022, Cell chemical biology.

Tokaramide A, a new cathepsin B inhibitor from the marine sponge Theonella aff. mirabilis.

S. Matsunaga, N. Fusetani, Y. Nakao, 1999, Bioorganic & medicinal chemistry letters.

Bioactive Marine Metabolites. Part 107. Isolation and Structure Elucidation of Two Phosphorylated Sterol Sulfates, MT1-MMP Inhibitors from a Marine Sponge Cribrochalina sp.: Revision of the Structures of Haplosamates A and B.

Y. Itoh, S. Matsunaga, M. Seiki, 2001 .

Calyceramides A–C: neuraminidase inhibitory sulfated ceramides from the marine sponge Discodermia calyx 1

S. Matsunaga, N. Fusetani, Y. Nakao, 2001 .

Preparation and Application of a Chemical Probe for Identifying the Targets of the Marine Cyclic Peptide Kapakahine A

Y. Nakao, Rie Kamihira, 2022, Molecules.

Cyclotheonamides E2 and E3, new potent serine protease inhibitors from the marine sponge of the genus Theonella.

S. Matsunaga, N. Fusetani, N. Oku, 1998, Journal of natural products.

Three more cyclotheonamides, C, D, and E, potent thrombin inhibitors from the marine sponge Theonella swinhoei.

S. Matsunaga, N. Fusetani, Y. Nakao, 1995, Bioorganic & medicinal chemistry.

Schulzeines A-C, new alpha-glucosidase inhibitors from the marine sponge Penares schulzei.

Taisuke Uehara, S. Matsunaga, N. Fusetani, 2004, Journal of the American Chemical Society.

Ageladine A: an antiangiogenic matrixmetalloproteinase inhibitor from the marine sponge Agelas nakamurai.

Y. Itoh, S. Matsunaga, M. Seiki, 2003, Journal of the American Chemical Society.

Enzyme inhibitors from marine invertebrates.

N. Fusetani, Y. Nakao, 2007, Journal of natural products.

A one-pot synthesis and biological activity of ageladine A and analogues.

L. Meijer, C. Parish, P. Karuso, 2011, Journal of medicinal chemistry.

Marine invertebrates: Sponges

N. Fusetani, Y. Nakao, 2010 .

KUMUSINE, A CHLOROADENINE RIBOSIDE FROM A SPONGE, THEONELLA SP.

M. Kelly-Borges, P. Scheuer, Y. Nakao, 1995 .

Carteramine A, an inhibitor of neutrophil chemotaxis, from the marine sponge Stylissa carteri.

S. Matsunaga, N. Fusetani, Y. Nakao, 2007 .

Ciliatamides A-C, bioactive lipopeptides from the deep-sea sponge Aaptos ciliata.

S. Matsunaga, M. Okamoto, N. Fusetani, 2008, Journal of natural products.

The Kapakahines, Cyclic Peptides from the Marine Sponge Cribrochalina olemda.

M. Kelly-Borges, J. Carney, P. Scheuer, 1996, The Journal of organic chemistry.

Penarolide Sulfates A1 and A2, New α-Glucosidase Inhibitors from a Marine Sponge Penares sp.

S. Matsunaga, N. Fusetani, Takashi Maki, 2000 .

Perplexing distribution of 3-alkylpyridines in haplosclerid sponges

S. Matsunaga, L. Becking, N. Fusetani, 2007 .

Synthesis and antileishmanial activity of the core structure of cristaxenicin A.

Y. Goto, Y. Osada, S. Hosokawa, 2016, Bioorganic & medicinal chemistry letters.

Total Synthesis and Biological Evaluation of Kakeromamide A and Its Analogues

Y. Nakao, T. Ye, Satoshi Otsuka, 2020, Frontiers in Chemistry.

A quantitative shRNA screen identifies ATP1A1 as a gene that regulates cytotoxicity by aurilide B

Minoru Yoshida, Ken Matsumoto, R. Kurokawa, 2017, Scientific Reports.

Miraziridine A, a Novel Cysteine Protease Inhibitor from the Marine Sponge Theonella aff. mirabilis1

S. Matsunaga, N. Fusetani, Y. Nakao, 2000 .

Asteropine A, a sialidase-inhibiting conotoxin-like peptide from the marine sponge Asteropus simplex.

H. Hirota, S. Matsunaga, N. Fusetani, 2006, Chemistry & biology.

Callyspongynic acid, a polyacetylenic acid which inhibits alpha-glucosidase, from the marine sponge Callyspongia truncata.

Taisuke Uehara, S. Matsunaga, N. Fusetani, 2002, Journal of natural products.

Sodium 1-(12-hydroxy)octadecanyl sulfate, an MMP2 inhibitor, isolated from a tunicate of the family Polyclinidae.

S. Matsunaga, T. Nishikawa, N. Fusetani, 2002, Journal of natural products.

Shishicrellastatins, inhibitors of cathepsin B, from the marine sponge Crella (Yvesia) spinulata.

S. Okada, S. Matsunaga, Y. Nakao, 2011, Bioorganic & medicinal chemistry.

Cinanthrenol A, an estrogenic steroid containing phenanthrene nucleus, from a marine sponge Cinachyrella sp.

N. D. de Voogd, N. Fusetani, Y. Nakao, 2014, Organic letters.

More kapakahines from the marine sponge Cribrochalina olemda.

P. Scheuer, M. Kelly, Y. Nakao, 2003, Organic letters.

Absolute structure of prunustatin A, a novel GRP78 molecular chaperone down-regulator.

K. Shin‐ya, T. Doi, M. Takagi, 2007, Organic letters.

Direct Guanylation of Amino Groups by Cyanamide in Water: Catalytic Generation and Activation of Unsubstituted Carbodiimide by Scandium(III) Triflate

Katsunori Tanaka, K. Fukase, Kazuki Tsubokura, 2014, Synlett.

In Vitro Modeling of Blood-Brain Barrier with Human iPSC-Derived Endothelial Cells, Pericytes, Neurons, and Astrocytes via Notch Signaling

H. Inoue, M. Nakagawa, Mio Iwasaki, 2017, Stem cell reports.

Sameuramide A, a new cyclic depsipeptide isolated from an ascidian of the family Didemnidae.

Shoubin Tang, N. Fusetani, J. Yamashita, 2018, Bioorganic & medicinal chemistry.

Axinelloside A, an unprecedented highly sulfated lipopolysaccharide inhibiting telomerase, from the marine sponge, Axinella infundibula.

H. Hirota, S. Matsunaga, N. Fusetani, 2005, Journal of the American Chemical Society.

Kulolide: A cytotoxic depsipeptide from a cephalaspidean mollusk, Philinopsis speciosa

M. Hamann, P. Scheuer, Y. Nakao, 1996 .

Structure-activity relationship study on 13-deoxytedanolide, a highly antitumor macrolide from the marine sponge Mycale adhaerens.

H. Hirota, S. Matsunaga, N. Fusetani, 2005, Bioorganic & medicinal chemistry.

A Soft Spot for Chemistry–Current Taxonomic and Evolutionary Implications of Sponge Secondary Metabolite Distribution

P. Schupp, G. Wörheide, D. Erpenbeck, 2021, Marine drugs.

Bioactive Marine Metabolites. Part 106. Calyceramides A—C (I): Neuraminidase Inhibitory Sulfated Ceramides from the Marine Sponge Discodermia Calyx

S. Matsunaga, N. Fusetani, Y. Nakao, 2001 .

Halenaquinone, a chemical compound that specifically inhibits the secondary DNA binding of RAD51

H. Kurumizaka, Motoki Takaku, Y. Nakao, 2011, Genes to cells : devoted to molecular & cellular mechanisms.

Cytotoxic C47-polyacetylene carboxylic acids from a marine sponge Pertrosia sp.

T. Iwashita, S. Matsunaga, N. Fusetani, 2007, Journal of natural products.

An epigenetic regulatory element of the Nodal gene in the mouse and human genomes

J. Ohgane, Satoshi Tanaka, K. Shiota, 2015, Mechanisms of Development.

Histone modification dynamics as revealed by multicolor immunofluorescence-based single-cell analysis

T. Nagase, H. Kimura, N. Nozaki, 2020, Journal of Cell Science.

Histone modification dynamics as revealed by a multicolor immunofluorescence-based single-cell analysis

T. Nagase, H. Kimura, N. Nozaki, 2020, bioRxiv.

Epigenetic effects of insecticides on early differentiation of mouse embryonic stem cells.

J. Ohgane, H. Sone, K. Abe, 2021, Toxicology in vitro : an international journal published in association with BIBRA.

Koshikamide A1, a new cytotoxic linear peptide isolated from a marine sponge, Theonella sp.

S. Matsunaga, N. Fusetani, Y. Nogata, 1999 .

Nobiloside, a new neuraminidase inhibitory triterpenoidal saponin from the marine sponge Erylus nobilis.

S. Matsunaga, N. Fusetani, Y. Nakao, 2002, Journal of natural products.

Identification of Renieramycin A as an Antileishmanial Substance in a Marine Sponge Neopetrosia sp.

Y. Goto, S. Matsunaga, N. Fusetani, 2004, Marine Drugs.

Identification of zinc finger transcription factor EGR2 as a novel acetylated protein.

Minoru Yoshida, A. Ito, Y. Nakao, 2017, Biochemical and biophysical research communications.

Effect of mycalolides isolated from a marine sponge Mycale aff. nullarosette on actin in living cells

H. Kimura, Yoko Hayashi-Takanaka, S. Yamazaki, 2019, Scientific Reports.

Efficient biallelic knock-in in mouse embryonic stem cells by in vivo-linearization of donor and transient inhibition of DNA polymerase θ/DNA-PK

Y. Nakao, D. Arai, 2021, Scientific Reports.

Two Onnamide Analogs from the Marine Sponge Theonella conica: Evaluation of Geometric Effects in the Polyene Systems on Biological Activity

N. Fusetani, Fumiaki Nakamura, Y. Nakao, 2023, Molecules.

Triggering Growth via Growth Initiation Factors in Nature: A Putative Mechanism for in situ Cultivation of Previously Uncultivated Microorganisms

T. Kindaichi, Y. Aoi, Dawoon Jung, 2021, Frontiers in Microbiology.

Cultivating in situ triggers growth of previously uncultivated microorganisms via a growth initiation factor in nature

T. Kindaichi, Y. Aoi, Dawoon Jung, 2019, bioRxiv.

Asteropterin, an inhibitor of cathepsin B, from the marine sponge Asteropus simplex

S. Matsunaga, Y. Nakao, Y. Nakao, 2008 .

Combinatorial Effects of Soluble, Insoluble, and Organic Extracts from Jerusalem Artichokes on Gut Microbiota in Mice

S. Shibata, Hiroyuki Sasaki, Fumiaki Nakamura, 2020, Microorganisms.

T. Tashiro, Y. Nakao, T. Negishi, 2012, Bioorganic & medicinal chemistry letters.

Cristaxenicin A, an antiprotozoal xenicane diterpenoid from the deep sea gorgonian Acanthoprimnoa cristata.

Y. Goto, H. Nakai, Yukimitsu Imahara, 2012, The Journal of organic chemistry.

Aplysinoplides A-C, cytotoxic sesterterpenes from the marine sponge Aplysinopsis digitata.

R. Ueoka, S. Matsunaga, Y. Nakao, 2008, Journal of natural products.

Callysponginol sulfate A, an MT1-MMP inhibitor isolated from the marine sponge Callyspongia truncata.

Y. Itoh, S. Matsunaga, M. Seiki, 2003, Journal of natural products.

Mutualistic relationship between Nitrospira and concomitant heterotrophs

T. Kindaichi, Y. Aoi, A. Ohashi, 2021, Environmental microbiology reports.

Stereochemical analysis and cytotoxicity of kulokekahilide-2 and its analogues

Y. Nakao, T. Negishi, M. Umehara, 2013 .

Halistanol sulfates I and J, new SIRT1–3 inhibitory steroid sulfates from a marine sponge of the genus Halichondria

Minoru Yoshida, A. Ito, N. Kudo, 2017, The Journal of Antibiotics.

Dogger Bank Itch revisited: isolation of (2-hydroxyethyl) dimethylsulfoxonium chloride as a cytotoxic constituent from the marine sponge Theonella aff. mirabilis.

S. Matsunaga, N. Fusetani, Y. Nakao, 2001, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Complete structure elucidation of shishididemniols, complex lipids with tyramine-derived tether and two serinol units, from a marine tunicate of the family Didemnidae.

T. Iwashita, S. Matsunaga, N. Fusetani, 2007, The Journal of organic chemistry.

Penasulfate A, a new α-glucosidase inhibitor from a marine sponge Penares sp.

S. Matsunaga, R. V. Soest, N. Fusetani, 2004 .

Application of a 6pi-1-azatriene electrocyclization strategy to the total synthesis of the marine sponge metabolite ageladine A and biological evaluation of synthetic analogues.

N. Fusetani, Y. Nakao, S. Weinreb, 2007, The Journal of organic chemistry.

Azumamides A-E: histone deacetylase inhibitory cyclic tetrapeptides from the marine sponge Mycale izuensis.

A. Ganesan, S. Matsunaga, N. Shindoh, 2006, Angewandte Chemie.

Kulokekahilide-1, a cytotoxic depsipeptide from the cephalaspidean mollusk Philinopsis speciosa.

P. Scheuer, Y. Nakao, G. Goetz, 2002, The Journal of organic chemistry.

11 C-Labeling of the C(1)-C(10) Dihydroxy Acid Moiety for the Study on the Synthesis of Kulokekahilide-2 PET Tracer

Masaaki Suzuki, H. Doi, Y. Nakao, 2014 .

Inhibition of protein SUMOylation by davidiin, an ellagitannin from Davidia involucrata

H. Handa, Y. Yamaguchi, Minoru Yoshida, 2014, The Journal of Antibiotics.

Small-Scale Preparation of Fluorescently Labeled Chemical Probes from Marine Cyclic Peptides, Kapakahines A and F

Y. Nakao, Rie Kamihira, 2021, Marine drugs.

Coronarin D, a Metabolite from the Wild Turmeric, Curcuma aromatica, Promotes the Differentiation of Neural Stem Cells into Astrocytes

M. Kawamura, N. Fusetani, Fumiaki Nakamura, 2022, Journal of agricultural and food chemistry.

Three new bromotyrosine derivatives lethal to crab from the marine sponge, Pseudoceratina purpurea

S. Matsunaga, N. Fusetani, Y. Nakao, 2001 .

iGEM as a human iPS cell-based global epigenetic modulation detection assay provides throughput characterization of chemicals affecting DNA methylation

W. Fujibuchi, H. Sone, K. Abe, 2023, Scientific reports.

Assay methods for small ubiquitin-like modifier (SUMO)-SUMO-interacting motif (SIM) interactions in vivo and in vitro using a split-luciferase complementation system.

Kam Y. J. Zhang, A. Voet, Minoru Yoshida, 2014, Analytical Biochemistry.

Ancorinosides B-D, inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP), from the marine sponge Penares sollasi Thiele.

Y. Itoh, S. Matsunaga, M. Seiki, 2001 .

Koshikamide B, a cytotoxic peptide lactone from a marine sponge Theonella sp.

S. Matsunaga, D. Faulkner, N. Fusetani, 2008, The Journal of organic chemistry.

Cupolamide A: A Cytotoxic Cyclic Heptapeptide from Two Samples of the Sponge Theonella cupola

P. Scheuer, J. Tanaka, Y. Nakao, 1997 .

Cupolamide A: A Cytotoxic Cyclic Heptapeptide from Two Samples of the Sponge Theonella cupola.

P. Scheuer, J. Tanaka, Y. Nakao, 1998 .

Pupukeamide, a Linear Tetrapeptide from a Cephalaspidean Mollusk Philinopsis speciosa.

P. Scheuer, Y. Nakao, W. Yoshida, 1997 .

The total synthesis and structure-activity relationships of a highly cytotoxic depsipeptide kulokekahilide-2 and its analogs

Y. Nakao, Y. Nakao, Yuuki Takada, 2012 .

Reinvestigation of the stereochemistry of kulokekahilide-2

Y. Nakao, Y. Nakao, Yuuki Takada, 2007 .

Penasulfate A, a new alpha-glucosidase inhibitor from a marine sponge Penares sp.

S. Matsunaga, N. Fusetani, Takashi Maki, 2004, Journal of Natural Products.

Total synthesis of azumamide A and azumamide E, evaluation as histone deacetylase inhibitors, and design of a more potent analogue.

A. Ganesan, G. Packham, N. Fusetani, 2007, Organic letters.

In Vivo Gold Complex Catalysis within Live Mice.

H. Onoe, Yasuyoshi Watanabe, Katsunori Tanaka, 2017, Angewandte Chemie.

Azumamides A-E: histone deacetylase inhibitory cyclic tetrapeptides from the marine sponge Mycale izuensis.

A. Ganesan, S. Matsunaga, N. Shindoh, 2006, Angewandte Chemie.

Waiakeamide, a Cyclic Hexapeptide from the Sponge Ircinia dendroides(1).

M. Kelly-Borges, P. Scheuer, Y. Nakao, 1996, Journal of Organic Chemistry.