A. Leff

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Respiratory Physiology: Basics and Applications

P. Schumacker, A. Leff, 1993 .

A genome-wide search for asthma susceptibility loci in ethnically diverse populations

Farhad Imani, Alan R. Leff, James L. Weber, 1997, Nature Genetics.

Augmentation of eosinophil degranulation and LTC4 secretion by integrin-mediated endothelial cell adhesion.

K. Rabe, H. Sano, K. Hamann, 1999, American journal of physiology. Lung cellular and molecular physiology.

Augmentation of eosinophil degranulation and LTC(4) secretion by integrin-mediated endothelial cell adhesion.

K. Rabe, H. Sano, K. Hamann, 1999, The American journal of physiology.

Outcomes after long-term acute care. An analysis of 133 mechanically ventilated patients.

P. Bach, S. Carson, A. Leff, 1999, American journal of respiratory and critical care medicine.

Mitogen-Activated Protein Phosphoinositide 3-Kinase Through a Phospholipase A2 in Human Eosinophils by Activation of Group IV Cytosolic

A. Leff, Xiangdong Zhu, A. Meliton, 2013 .

Regulation of interleukin-5-induced beta2-integrin adhesion of human eosinophils by phosphoinositide 3-kinase.

S. Myou, A. Leff, Xiangdong Zhu, 2005, American journal of respiratory cell and molecular biology.

Kinase-Independent Pathway Mitogen-Activated Protein Phosphoinositide 3-Kinase Through a in Human Eosinophils by 2 Phospholipase A Activation of Group IV Cytosolic

Xu, S. Myou, A. Leff, 2003 .

Blockade of Inflammation and Airway Hyperresponsiveness in Immune-sensitized Mice by Dominant-Negative Phosphoinositide 3-Kinase–TAT

S. Myou, J. Tong, A. Leff, 2003, The Journal of experimental medicine.

Activation of Group IV Cytosolic Phospholipase A2 in Human Eosinophils by Phosphoinositide 3-Kinase Through a Mitogen-Activated Protein Kinase-Independent Pathway 1

S. Myou, A. Leff, Xiangdong Zhu, 2003, The Journal of Immunology.

Glucocorticoid-induced surface expression of annexin 1 blocks beta2-integrin adhesion of human eosinophils to intercellular adhesion molecule 1 surrogate protein.

Chang Xu, Malcolm W Johnson, A. Leff, 2005, The Journal of allergy and clinical immunology.

Impact factor and its role in academic promotion.

R. Glenny, V. Brusasco, K. Adler, 2009, European Respiratory Journal.

Migration of human and guinea pig airway epithelial cells in response to calcitonin gene-related peptide.

H. Magnussen, K. Rabe, J. S. Kim, 1994, American journal of respiratory cell and molecular biology.

Roles of Trp31 in High Membrane Binding and Proinflammatory Activity of Human Group V Phospholipase A2 *

M. Gelb, R. Koduri, D. Wilton, 1999, The Journal of Biological Chemistry.

Mechanism of Human Group V Phospholipase A2(PLA2)-induced Leukotriene Biosynthesis in Human Neutrophils

Y. Snitko, W. Cho, A. Leff, 2001, The Journal of Biological Chemistry.

Churg-Strauss syndrome

I. Noth, M. Strek, A. Leff, 2003, The Lancet.

Panel 1 : Definitions of Churg-Strauss syndrome

I. Noth, M. Strek, A. Leff, 2022 .

Identifying patients at risk from the use of beta-adrenergic agonists.

A. Leff, 1996, American journal of respiratory and critical care medicine.

Outcomes and resource utilization for patients with prolonged critical illness managed by university-based or community-based subspecialists.

P. Bach, S. Carson, A. Leff, 1998, American journal of respiratory and critical care medicine.

Regulation of leukotrienes in the management of asthma: biology and clinical therapy.

A. Leff, Alan R. Leff, 2001, Annual review of medicine.

Group V Phospholipase A2 Induces Leukotriene Biosynthesis in Human Neutrophils through the Activation of Group IVA Phospholipase A2 *

H. Sano, W. Cho, A. Leff, 2002, The Journal of Biological Chemistry.

Current treatment modes for tuberculosis. Public policy and implementation.

D. Leff, A. Leff, 1985, Chest.

Tuberculosis control policies in major metropolitan health departments in the United States. VI. Standard of practice in 1996.

D. Leff, A. Leff, 1997, American journal of respiratory and critical care medicine.

Tuberculosis control policies in major metropolitan health departments in the United States. V. Standard of practice in 1992.

D. Leff, A. Leff, 1993, The American review of respiratory disease.

The pathogenesis of pulmonary and miliary tuberculosis.

A. Leff, E. Geppert, 1979, Archives of internal medicine.

Conservation of bronchiolar wall area during constriction and dilation of human airways.

H. Magnussen, K. Rabe, A. Leff, 1997, Journal of applied physiology.

Distribution of airway contractile responses within the major diameter bronchi during exogenous bronchoconstriction.

T. Shioya, J. Solway, A. Leff, 2015, The American review of respiratory disease.

Translation of contractile force to constriction in major diameter canine airways in vivo.

T. Shioya, A. Leff, N. Muñoz, 1989, The American review of respiratory disease.

Parasympathetic involvement in PAF-induced contraction in canine trachealis in vivo.

T. Shioya, A. Leff, S. White, 1987, Journal of applied physiology.

Hematopoietic Pyk2 regulates migration of differentiated HL-60 cells

A. Leff, Xiangdong Zhu, Yingli Duan, 2010, Journal of Inflammation.

ResearchPyk2 regulates migration of differentiated HL-60 cells

A. Leff, Xiangdong Zhu, Yingli Duan, 2010 .

Passive sensitization of human bronchi augments smooth muscle shortening velocity and capacity.

H. Magnussen, K. Rabe, A. Leff, 1994, The American journal of physiology.

Inflammatory mediation of airway hyperresponsiveness by peripheral blood granulocytes. The case for the eosinophil.

A. Leff, Alan R. Leff, 1994, Chest.

Augmentation of stimulated eosinophil degranulation by VLA-4 (CD49d)-mediated adhesion to fibronectin.

K. Hamann, A. Leff, S. White, 1994, American journal of respiratory cell and molecular biology.

Contraction of human bronchial smooth muscle caused by activated human eosinophils.

H. Magnussen, K. Rabe, A. Leff, 1994, The American journal of physiology.

Role of leukotrienes in bronchial hyperresponsiveness and cellular responses in airways.

A. Leff, 2000, Thorax.

Role of leukotrienes in bronchial hyperresponsiveness and cellular responses in airways

A. Leff, 2000, American journal of respiratory and critical care medicine.

Blockade of eosinophil migration and airway hyperresponsiveness by cPLA2-inhibition

K. Kurashima, H. Sano, W. Cho, 2001, Nature Immunology.

Regulation of human eosinophil degranulation and activation by endogenous phospholipase A2.

M. Strek, A. Leff, S. White, 1993, The Journal of clinical investigation.

IL‐5‐induced integrin adhesion of human eosinophils caused by ERK1/2‐mediated activation of cPLA2

H. Sano, S. Myou, A. Leff, 2002, Journal of leukocyte biology.

Human Eosinophils Activation in Arachidonic Acid Metabolism 2 Kinase-Mediated Cytosolic Phospholipase A Role of Mitogen-Activated Protein

H. Sano, W. Cho, A. Leff, 2001 .

Role of Mitogen-Activated Protein Kinase-Mediated Cytosolic Phospholipase A2 Activation in Arachidonic Acid Metabolism in Human Eosinophils1

H. Sano, W. Cho, A. Leff, 2001, The Journal of Immunology.

Extracellular Signal-Regulated Kinase 1/2-Mediated Phosphorylation of Cytosolic Phospholipase A2 Is Essential for Human Eosinophil Adhesion to Fibronectin1

H. Sano, T. Shioya, A. Leff, 2001, The Journal of Immunology.

Eosinophil Adhesion to Fibronectin Is Essential for Human 2 Phospholipase A 1 / 2-Mediated Phosphorylation of Cytosolic Extracellular Signal-Regulated Kinase

H. Sano, T. Shioya, A. Leff, 2001 .

A surrogate method for assessment of beta(2)-integrin-dependent adhesion of human eosinophils to ICAM-1.

H. Sano, A. Leff, A. Sano, 2000, Journal of immunological methods.

Selectivity of the Intrinsic Sympathomimetic Activity of the β‐Adrenergic Blocking Drug Bucindolol

E. Garrity, A. Leff, N. Muñoz, 1984, Journal of cardiovascular pharmacology.

Involvement of protein tyrosine kinases in activation of human eosinophils by platelet‐activating factor

H. Magnussen, K. Rabe, G. Dent, 2000, Immunology.

12 – Immunopharmacology of the Eosinophil in Asthma

A. Leff, 1993 .

Human Group V Phospholipase A2 Induces Group IVA Phospholipase A2-independent Cysteinyl Leukotriene Synthesis in Human Eosinophils*

J. Bonventre, W. Cho, S. Myou, 2003, Journal of Biological Chemistry.

Characterization of monoclonal antibodies specific for 14-kDa human group V secretory phospholipase A2 (hVPLA2).

H. Sano, S. K. Han, W. Cho, 2000, Hybridoma.

Studying human airway pharmacology in microsections: application of videomicrometry

K. Rabe, G. Dent, A. Leff, 1999, European Respiratory Journal.

Passive sensitization of human airways induces myogenic contractile responses in vitro.

H. Magnussen, K. Rabe, A. Leff, 1997, Journal of applied physiology.

Transcellular Secretion of Group V Phospholipase A2 from Epithelium Induces β2-Integrin-Mediated Adhesion and Synthesis of Leukotriene C4 in Eosinophils1

W. Cho, A. Leff, Xiangdong Zhu, 2006, The Journal of Immunology.

Direct effects and augmentation of airway smooth muscle contraction caused by phospholipase A2.

M. Strek, A. Leff, A. Garland, 1992, The American review of respiratory disease.

Immunobiology of Asthma and Rhinitis Pathogenic Factors and Therapeutic Options

A. Leff, 1999 .

Relationship of cellular transmigration and airway response after allergen challenge.

M. Waldman, E. Naureckas, I. Ndukwu, 1999, American journal of respiratory and critical care medicine.

Highly purified selective isolation of eosinophils from human peripheral blood by negative immunomagnetic selection

A. Leff, N. Muñoz, 2006, Nature Protocols.

Inflammation and cell-cell interactions in airway hyperresponsiveness.

C. Wegner, K. Hamann, A. Leff, 1991, The American journal of physiology.

Effect of enantiomeric forms of albuterol on stimulated secretion of granular protein from human eosinophils.

R. Naclerio, F. Baroody, D. Handley, 1997, Pulmonary pharmacology & therapeutics.

Selective regulation of expression of surface adhesion molecules Mac-1, L-selectin, and VLA-4 on human eosinophils and neutrophils.

K. Hamann, A. Leff, S. White, 1993, American journal of respiratory cell and molecular biology.

Epithelium-dependent contraction of airway smooth muscle caused by eosinophil MBP.

G. Gleich, J. Solway, A. Leff, 1990, The American journal of physiology.

Inhibition of cPLA2 translocation and leukotriene C4 secretion by fluticasone propionate in exogenously activated human eosinophils.

J. Choi, H. Sano, A. Leff, 1999, American journal of respiratory and critical care medicine.

Cytosolic phospholipase A2 activation is essential for beta 1 and beta 2 integrin-dependent adhesion of human eosinophils.

H. Sano, A. Leff, N. Muñoz, 1999, Journal of immunology.

Proline-rich tyrosine kinase 2 regulates spreading and migration of eosinophils after beta2-integrin adhesion.

A. Leff, Xiangdong Zhu, Yingli Duan, 2008, American journal of respiratory cell and molecular biology.

Additive blockade of β2‐integrin adhesion of eosinophils by salmeterol and fluticasone propionate For editorial comments see page 501.

S. Myou, A. Leff, A. Meliton, 2004, European Respiratory Journal.

Additive blockade of beta 2-integrin adhesion of eosinophils by salmeterol and fluticasone propionate.

S. Myou, A. Leff, A. Meliton, 2004, European Respiratory Journal.

Eosinophil chemotaxis inhibited by 5-lipoxygenase blockade and leukotriene receptor antagonism.

A. Leff, I. Douglas, N. Muñoz, 1997, American journal of respiratory and critical care medicine.

CD4+ T Cell and Eosinophil Adhesion Is Mediated by Specific ICAM-3 Ligation and Results in Eosinophil Activation1

I. Douglas, A. Sperling, A. Leff, 2000, The Journal of Immunology.

Future directions in asthma therapy. Is a cure possible?

A. Leff, 1997, Chest.

Pharmacologic management of asthma.

A. Leff, Alan R. Leff, 1998, The Journal of allergy and clinical immunology.

Effects of activated eosinophils cultured from human umbilical cord blood on guinea pig trachealis.

M. Strek, K. Hamann, A. Leff, 1993, The American journal of physiology.

Activated eosinophils elicit substance P release from cultured dorsal root ganglion neurons.

J. Solway, A. Leff, A. Garland, 1997, The American journal of physiology.

Canine bronchoconstriction, gas trapping, and hypoxia with methacholine.

P. Breen, P. Ruygrok, A. Leff, 1987, Journal of applied physiology.

Beta2-integrin adhesion caused by eotaxin but not IL-5 is blocked by PDE-4 inhibition and beta2-adrenoceptor activation in human eosinophils.

Chang Xu, S. Myou, Malcolm W Johnson, 2004, Pulmonary pharmacology & therapeutics.

Protein kinase C inhibition enhances platelet-activating factor-induced eicosanoid production in human eosinophils.

H. Magnussen, K. Rabe, G. Dent, 1998, American journal of respiratory cell and molecular biology.

Blockade of Airway Inflammation and Hyperresponsiveness by HIV-TAT-Dominant Negative Ras 1

S. Myou, A. Leff, Xiangdong Zhu, 2003, The Journal of Immunology.

EP1 receptor blockade attenuates both spontaneous tone and PGE2-elicited contraction in guinea pig trachealis.

I. Ndukwu, A. Leff, S. White, 1997, The American journal of physiology.

Advances in the understanding and future therapy of COPD

S. Rennard, L. Fabbri, B. O'connor, 2002 .

Additive effect of cysteinyl leukotriene or thromboxane modifiers to inhaled corticosteroids in asthmatic patients

M. Fujimura, S. Myou, A. Leff, 2004 .

Structural determinants of blockade of eosinophil activation, adhesion and secretion by synthetic analogs of phomactin.

V. Rawal, A. Leff, Xiangdong Zhu, 2003, Life sciences.

Blockade of LTC4 synthesis caused by additive inhibition of gIV-PLA2 phosphorylation: Effect of salmeterol and PDE4 inhibition in human eosinophils.

S. Myou, Malcolm W Johnson, A. Leff, 2003, The Journal of allergy and clinical immunology.

Beta adrenergic modulation of formyl-methionine-leucine-phenylalanine-stimulated secretion of eosinophil peroxidase and leukotriene C4.

A. Leff, S. White, N. Muñoz, 1994, The Journal of pharmacology and experimental therapeutics.

Regulation of eosinophil function by phosphatidylinositol-specific PLC and cytosolic PLA(2).

H. Sano, A. Leff, A. Sano, 2001, American journal of physiology. Lung cellular and molecular physiology.

A kinetic assay for eosinophil peroxidase activity in eosinophils and eosinophil conditioned media.

A. Leff, S. White, S. Spaethe, 1991, Journal of immunological methods.

Homeostatic regulation of bronchomotor tone by sympathetic activation during bronchoconstriction in normal and asthmatic humans.

G. Robertson, A. Leff, F. Douglas, 1985, The American review of respiratory disease.

Paradoxical blockade of beta adrenergically mediated inhibition of stimulated eosinophil secretion by salmeterol.

K. Rabe, A. Leff, N. Muñoz, 1995, The Journal of pharmacology and experimental therapeutics.

Tachykinin receptor antagonists inhibit hyperpnea-induced bronchoconstriction in guinea pigs.

J. Howbert, I. Rodger, J. Solway, 1993, The Journal of clinical investigation.

Augmentation of respiratory mast cell secretion of histamine caused by vagus nerve stimulation during antigen challenge.

T. Shioya, A. Leff, N. Muñoz, 1986, Journal of immunology.

Adhesion of Human Eosinophils Integrin-Dependent 2 β and 1 β Essential for Activation Is 2 Cytosolic Phospholipase A

H. Sano, W. Cho, A. Leff, 2022 .

Deletion of Secretory Group V Phospholipase A2 Attenuates Cell Migration and Airway Hyperresponsiveness in Immunosensitized Mice1

J. Bonventre, W. Cho, J. Arm, 2007, The Journal of Immunology.

Attenuated translocation of group IVa phospholipase A2 and up‐regulated annexin‐1 synthesis by glucocorticoid blocks β2‐integrin adhesion in neutrophils

A. Leff, Xiangdong Zhu, A. Meliton, 2008, Journal of leukocyte biology.

Endogenous sensory neuropeptide release enhances nonspecific airway responsiveness in guinea pigs.

T. Hsiue, J. Solway, M. Hershenson, 1992, The American review of respiratory disease.

Dose-response relationships in determining the safety:efficacy ratio.

A. Leff, 1997, Respiratory medicine.

Impaired sensorineural function after allergen-induced mediator release.

T. Hsiue, J. Solway, M. Hershenson, 1993, The American review of respiratory disease.

Tachykinins mediate bronchoconstriction elicited by isocapnic hyperpnea in guinea pigs.

J. Drazen, J. Solway, A. Leff, 1989, Journal of applied physiology.

Physiological Transition from Fetal to Neonatal Life in Pregnancy

A. Leff, 2009 .

Inhibition of Pyk2 blocks airway inflammation and hyperresponsiveness in a mouse model of asthma.

B. Clay, A. Leff, Xiangdong Zhu, 2009, American journal of respiratory cell and molecular biology.

Discovery of leukotrienes and development of antileukotriene agents.

A. Leff, Alan R. Leff, 2001, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Augmented muscarinic responsiveness caused by 5-lipoxygenase products secreted from alveolar macrophages in isolated-perfused rat lung.

J. Solway, A. Leff, P. Padrid, 1993, American Review of Respiratory Disease.

Epithelial augmentation of trachealis contraction caused by major basic protein of eosinophils.

G. Gleich, A. Leff, S. White, 1989, Journal of applied physiology.

Ontogeny of shortening velocity in porcine trachealis.

K. Ikeda, A. Leff, R. Mitchell, 1992, The American journal of physiology.

Ca2+-dependent facilitated shortening in isotonic contraction of trachealis muscle.

N. Stephens, A. Leff, R. Mitchell, 1989, Journal of applied physiology.

Tuberculosis chemotherapy practices in major metropolitan clinics in the United States

A. Leff, A. Brewin, 1981 .

Results in Eosinophil Activation Mediated by Specific ICAM-3 Ligation and T Cell and Eosinophil Adhesion Is + CD4

I. Douglas, A. Sperling, A. Leff, 2000 .

Negative Ras Hyperresponsiveness by HIV-TAT-Dominant Blockade of Airway Inflammation and

S. Myou, A. Leff, Xiangdong Zhu, 2003 .

Neurohumoral regulation of airway contractile responses.

A. Leff, 1988, Chest.

Pathophysiology of Asthmatic Bronchoconstriction

A. Leff, 1982 .

Pathogenesis of asthma. Neurophysiology and pharmacology of bronchospasm.

A. Leff, 1982, Chest.

Eosinophil VLA-4 binding to fibronectin augments bronchial narrowing through 5-lipoxygenase activation.

H. Magnussen, K. Rabe, A. Leff, 1996, The American journal of physiology.

Augmentation of LTC4 synthesis in human eosinophils caused by CD3-stimulated Th2-like cells in vitro

A. Leff, N. Muñoz, R. Semnani, 2000 .

Effect of interleukin-5 exposure during in vitro eosinophilopiesis on MAC-1 adhesion molecule expression and function on cultured human eosinophils.

K. Hamann, A. Leff, S. Neeley, 1996, Blood.

Persistent airway hyperresponsiveness and histologic alterations after chronic antigen challenge in cats.

J. Solway, A. Leff, P. Padrid, 1995, American journal of respiratory and critical care medicine.

Differential effects of cyclosporine A after acute antigen challenge in sensitized cats in vivo and ex vivo

A. Leff, P. Padrid, R. Mitchell, 1998, British journal of pharmacology.

Regulation of eosinophil adhesion by lysophosphatidylcholine via a non-store-operated Ca2+ channel.

V. Natarajan, A. Leff, Xiangdong Zhu, 2007, American journal of respiratory cell and molecular biology.

Phosphodiesterase 4 inhibition of β2-integrin adhesion caused by leukotriene B4 and TNF-α in human neutrophils

A. Leff, Xiangdong Zhu, A. Meliton, 2006, European Respiratory Journal.

Quantitation of secretory group V phospholipase A(2) in human tissues by sandwich enzyme-linked immunosorbent assay.

W. Cho, A. Sperling, A. Leff, 2002, Journal of immunological methods.

Upregulated surface expression of intracellularly sequestered Igε receptors (FcεRII/CD23) following activation in human peripheral blood eosinophils

H. Sano, John Choi, A. Leff, 1999 .

Intracellular expression of Fc gamma RIII (CD16) and its mobilization by chemoattractants in human eosinophils.

K. Hamann, A. Leff, N. Muñoz, 1998, Journal of immunology.

Quantitation of the cytosolic phospholipase A2 (type IV) in isolated human peripheral blood eosinophils by sandwich-ELISA.

A. Leff, I. Douglas, N. Muñoz, 1996, Journal of immunological methods.

Assessment of agonist- and cell-mediated responses in airway microsections by computerized videomicrometry.

K. Rabe, A. Leff, N. Muñoz, 1995, The American journal of physiology.

Effect of maturation on topographic distribution of bronchoconstrictor responses in large diameter airways of young swine.

A. Leff, N. Muñoz, R. Mitchell, 1991, The American review of respiratory disease.

Reduced activity of acetylcholinesterase in canine tracheal smooth muscle homogenates after active immune-sensitization.

A. Leff, R. Mitchell, E. Kelly, 1991, American journal of respiratory cell and molecular biology.

Hyaluronic acid enhances cell proliferation during eosinopoiesis through the CD44 surface antigen.

K. Hamann, A. Leff, S. Neeley, 1995, Journal of immunology.

Evidence for two subtypes of alpha adrenergic receptors in canine airway smooth muscle.

A. Leff, N. Muñoz, 1981, The Journal of pharmacology and experimental therapeutics.

Distribution of bronchoconstrictor responses in isolated-perfused rat lung.

N. Voelkel, C. Irvin, A. Leff, 1989, Journal of applied physiology.

Pertussis toxin augments beta-adrenergic relaxation of muscarinic contraction in canine trachealis.

A. Leff, R. Mitchell, S. Koenig, 1993, The American review of respiratory disease.

Direct effects on airway smooth muscle contractile response caused by endothelin-1 in guinea pig trachealis.

A. Leff, S. White, J. Umans, 1992, The American review of respiratory disease.

Iloprost improves endothelial barrier function in lipopolysaccharide-induced lung injury

A. Birukova, X. Tian, K. Birukov, 2012, European Respiratory Journal.

Group V phospholipase A2 increases pulmonary endothelial permeability through direct hydrolysis of the cell membrane

S. Dudek, A. Leff, L. Meliton, 2012, Pulmonary circulation.

Lysophosphatidic Acid Induces Interleukin-13 (IL-13) Receptor α2 Expression and Inhibits IL-13 Signaling in Primary Human Bronchial Epithelial Cells*

S. Georas, Yutong Zhao, V. Natarajan, 2007, Journal of Biological Chemistry.

The Masters Series

A. Leff, 2006 .

Bacillus cereus pneumonia. Survival in a patient with cavitary disease treated with gentamicin.

M. Stulbarg, A. Leff, R. Jacobs, 1977, The American review of respiratory disease.

Sympathetic secretory response to hypercapnic acidosis in swine.

A. Leff, S. White, N. Muñoz, 1990, Journal of applied physiology.

Group V phospholipase A2 mediates barrier disruption of human pulmonary endothelial cells caused by LPS in vitro.

S. Dudek, A. Leff, A. Meliton, 2011, American journal of respiratory cell and molecular biology.

Effect of mode of activation of human eosinophils on tracheal smooth muscle contraction in guinea pigs.

M. Strek, T. Hsiue, A. Leff, 1993, The American journal of physiology.

Cyclic nucleotide phosphodiesterase in human bronchial epithelial cells: characterization of isoenzymes and functional effects of PDE inhibitors.

H. Magnussen, K. Rabe, G. Dent, 1998, Pulmonary pharmacology & therapeutics.

Sympathetic modulation of biochemical and physiological response to immune degranulation in canine bronchial airways in vivo.

E. Garrity, A. Leff, N. Muñoz, 1985, The Journal of clinical investigation.

Radioenzymatic assay for measurement of tissue concentrations of histamine: adaptation to correct for adherence of histamine to mechanical homogenizers.

A. Leff, W. Gold, James K. Brown, 1984, The Journal of allergy and clinical immunology.

Interrelationship between alpha- and beta-adrenergic agonists and histamine in canine airways.

A. Leff, N. Muñoz, 1981, The Journal of allergy and clinical immunology.

Epithelial modulation of airway smooth muscle response to endothelin-1.

A. Leff, S. White, J. Umans, 1991, The American review of respiratory disease.

Physiologic and Pharmacologic Response Characteristics of Porcine Airways in Situ

E. Garrity, A. Leff, N. Muñoz, 1985 .

Future treatment to lessen exacerbations of chronic obstructive pulmonary disease.

A. Leff, N. Muñoz, 2007, Proceedings of the American Thoracic Society.

Circulatory heat sources for canine respiratory heat exchange.

J. Drazen, E. Ingenito, R. Ingram, 1986, The Journal of clinical investigation.

Radiofrequency ablation of airway smooth muscle for sustained treatment of asthma: preliminary investigations

W. Mitzner, A. Leff, John D. Miller, 2004, European Respiratory Journal.

The biology of leukotrienes, eosinophils, cytokines and nitric oxide in airway inflammation

A. Leff, 2001 .

Effect of immune sensitization on stimulated ACh release from trachealis muscle in vitro.

A. Leff, R. Mitchell, K. Arbetter, 1993, The American journal of physiology.

Leukotriene D4 activates β2-integrin adhesion in human polymorphonuclear leukocytes

A. Leff, L. Meliton, A. Meliton, 2009, European Respiratory Journal.

Blockade of avidity and focal clustering of beta 2-integrin by cysteinyl leukotriene antagonism attenuates eosinophil adhesion.

A. Leff, A. Meliton, N. Muñoz, 2007, The Journal of allergy and clinical immunology.

Ontogeny of dry gas hyperpnea-induced bronchoconstriction in guinea pigs.

J. Solway, A. Leff, L. Alger, 1994, Journal of applied physiology.

Blockade of eosinophil migration by 5-lipoxygenase and cyclooxygenase inhibition in explanted guinea pig trachealis.

A. Leff, N. Muñoz, 1995, The American journal of physiology.

Effect of airway inflammation on smooth muscle shortening and contractility in guinea pig trachealis.

J. Solway, I. Ndukwu, A. Leff, 1993, The American journal of physiology.

Association of granular exocytosis with Ca(2+)-activated K+ channels in human eosinophils.

R. Sato, T. Narahashi, A. Leff, 1997, The American journal of physiology.

Public health issues in control of tuberculosis. Surveillance techniques and the role of health care providers.

W. Stead, A. Leff, J. Sbarbaro, 1985, Chest.

Diffusing capacity predicts morbidity and mortality after pulmonary resection.

G. Glonek, A. Little, K. Popovich, 1988, The Journal of thoracic and cardiovascular surgery.

Mechanical induction of group V phospholipase A(2) causes lung inflammation and acute lung injury.

A. Birukova, K. Birukov, A. Leff, 2013, American journal of physiology. Lung cellular and molecular physiology.

Stimulation of Rho signaling by pathologic mechanical stretch is a "second hit" to Rho-independent lung injury induced by IL-6.

A. Birukova, K. Birukov, A. Leff, 2012, American journal of physiology. Lung cellular and molecular physiology.

Endotoxin in vivo impairs endothelium-dependent relaxation of canine arteries in vitro.

P. Schumacker, R. Samsel, A. Leff, 1990, The American review of respiratory disease.

Inhibition of Pyk2 blocks lung inflammation and injury in a mouse model of acute lung injury

A. Leff, Xiangdong Zhu, A. Meliton, 2012, Respiratory Research.

Epithelium-Dependent Responsiveness of Airway Smooth Muscle: The role of Epithelium-Derived Relaxant Factors

P. Barnes, M. Grunstein, A. Leff, 1997 .

Function after amputation, arthrodesis, or arthroplasty for tumors about the knee.

M. Simon, A. Leff, S. Gitelis, 1990, The Journal of bone and joint surgery. American volume.

Subtype-Specific Pharmacology

A. Leff, W. Addington, S. Rajfer, 1982 .

Oxidative stress contributes to lung injury and barrier dysfunction via microtubule destabilization.

A. Birukova, A. Leff, A. Meliton, 2012, American journal of respiratory cell and molecular biology.

Attenuation of lipopolysaccharide-induced lung vascular stiffening by lipoxin reduces lung inflammation.

M. Gardel, A. Birukova, K. Birukov, 2015, American journal of respiratory cell and molecular biology.

Sensory neuropeptides and airway function.

J. Solway, A. Leff, 1991, Journal of applied physiology.

Secretory group V phospholipase A2 regulates acute lung injury and neutrophilic inflammation caused by LPS in mice.

S. Dudek, A. Leff, L. Meliton, 2009, American journal of physiology. Lung cellular and molecular physiology.

Reduction in airway hyperresponsiveness to methacholine by the application of RF energy in dogs.

J. Hogg, C. Lombard, B. Loomas, 2004, Journal of applied physiology.

Cytosolic group IVa phospholipase A2 mediates IL-8/CXCL8-induced transmigration of human polymorphonuclear leukocytes in vitro

S. Dudek, A. Leff, L. Meliton, 2010, Journal of Inflammation.

Measurement of airway response by isometric and nonisometric techniques in situ.

A. Leff, N. Muñoz, B. Alderman, 1982, Journal of applied physiology: respiratory, environmental and exercise physiology.

Distribution of innervation and circulation in porcine cervical trachea.

A. Leff, N. Muñoz, L. Cera, 1984, American journal of veterinary research.

Tuberculosis control policies in major metropolitan health departments in the United States. IV. Standards in 1988.

D. Leff, A. Leff, 1989, The American review of respiratory disease.

Tuberculosis control practices in major metropolitan health departments in the United States. 3. Standard of practice in 1984.

D. Leff, A. Leff, 1985, Chest.

Effect of cooling on the responsiveness of canine tracheal muscle.

C. Irvin, S. Curtis, A. Leff, 1990, The American review of respiratory disease.

Physiological and pharmacological properties of canine trachealis muscle in vivo.

A. Leff, W. Gold, James K. Brown, 1980, Journal of applied physiology: respiratory, environmental and exercise physiology.

Pulmonary pharmacology and therapeutics

A. Leff, 1996 .

Public health and preventive aspects of pulmonary tuberculosis. Infectiousness, epidemiology, risk factors, classification, and preventive therapy.

A. Leff, E. Geppert, 1979, Archives of internal medicine.

Distribution of airway contractile responses in major resistance airways of the dog.

T. Shioya, A. Leff, N. Muñoz, 1987, The American journal of pathology.

Oscillatory hyperventilation in severe congestive heart failure secondary to idiopathic dilated cardiomyopathy or to ischemic cardiomyopathy.

C. Kremser, A. Leff, C B Kremser, 1987, The American journal of cardiology.

Potentiation of vagal contractile response by thromboxane mimetic U-46619.

S. Primack, T. Shioya, A. Leff, 1986, Journal of applied physiology.

Activated eosinophils elicit substance P release from cultured dorsal root ganglion neurons.

J. Solway, A. Leff, A. Garland, 1997, American journal of physiology. Lung cellular and molecular physiology.

Adhesion of bovine airway smooth muscle cells activates extracellular signal-regulated kinases.

M. Hershenson, K. Hamann, A. Leff, 1997, American journal of respiratory cell and molecular biology.

Heterogeneity of tracheobronchial lymphatic smooth muscle responses to histamine and 5-hydroxytryptamine.

M. Ferguson, A. Leff, R. Mitchell, 1993, Lymphology.

TAT-Protein Blockade during Ischemia/Reperfusion Reveals Critical Role for p85 PI3K-PTEN Interaction in Cardiomyocyte Injury

Z. Shao, A. Leff, L. Meliton, 2014, PloS one.

A novel pharmacological strategy by PTEN inhibition for improving metabolic resuscitation and survival after mouse cardiac arrest.

D. Beiser, E. Lewandowski, J. Costakis, 2015, American journal of physiology. Heart and circulatory physiology.

Cyclosporine A inhibits airway reactivity and remodeling after chronic antigen challenge in cats.

A. Leff, P. Padrid, P. Cozzi, 1996, American journal of respiratory and critical care medicine.

Tuberculosis chemotherapy practices in major metropolitan health departments in the United States.

D. Leff, A. Leff, A. Brewin, 2015, The American review of respiratory disease.

Tuberculosis chemoprophylaxis practices in metropolitan clinics.

A. Leff, A. Brewin, D. Herskowitz, 1979, The American review of respiratory disease.

Cytosolic Phospholipase A2 Activation Is Essential for β1 and β2 Integrin-Dependent Adhesion of Human Eosinophils

H. Sano, W. Cho, A. Leff, 1999, The Journal of Immunology.

How Clinical Observations of a Congenital Disease Can Be Translated in Terms of Molecular Biology

E. Mayr, R. Malouin, D. Luchins, 2015, Perspectives in biology and medicine.

Comparative distribution of cholinomimetic and parasympathetic contractile responses in the major diameter airways of dogs.

T. Shioya, A. Leff, N. Muñoz, 1988, Pulmonary pharmacology.

Endogenous regulation of bronchomotor tone.

A. Leff, 1988, American Review of Respiratory Disease.

Biochemical and physiological effects of compound 48/80 on canine trachea in vivo.

A. Leff, W. Gold, James K. Brown, 1983, Journal of applied physiology: respiratory, environmental and exercise physiology.

Effect of beta-adrenergic blockade and sympathetic stimulation on canine bronchial mast cell response to immune degranulation in vivo.

A. Leff, S. White, N. Muñoz, 1989, The American review of respiratory disease.

The ATS Journals' policy on image manipulation.

Steven D Shapiro, S. Shapiro, K. Adler, 2008, American journal of respiratory cell and molecular biology.

Blockade of Focal Clustering and Active Conformation in β2-Integrin-Mediated Adhesion of Eosinophils to Intercellular Adhesion Molecule-1 Caused by Transduction of HIV TAT-Dominant Negative Ras1

S. Myou, A. Leff, Xiangdong Zhu, 2002, The Journal of Immunology.

Physiologic significance of epithelial removal on guinea pig tracheal smooth muscle response to acetylcholine and serotonin.

M. Strek, I. Ndukwu, A. Leff, 1993, The American review of respiratory disease.

Parasympathetic and adrenergic contractile responses in canine trachea and bronchus.

A. Leff, N. Muñoz, S. Hendrix, 1983, Journal of applied physiology: respiratory, environmental and exercise physiology.

Highly sensitive determination of catecholamine and serotonin concentrations in plasma by liquid chromatography-electrochemistry.

A. Leff, N. Muñoz, C. Tutins, 1989, Journal of Chromatography A.

The Antileukotriene Working Group consensus conference overview.

A. Leff, 2001, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Physiological mechanisms mediating enhanced force generation during development and immune sensitization.

A. Leff, R. Mitchell, T. Murphy, 1992, Canadian journal of physiology and pharmacology.

Autonomic response characteristics of porcine airway smooth muscle in vivo.

E. Garrity, A. Leff, N. Muñoz, 1985, Journal of applied physiology.

Immortalization in culture: occurrence at a late stage in the progression of breast cancer.

S. Dairkee, H. Smith, M. Lippman, 1987, Journal of the National Cancer Institute.

Bioactivity of recombinant feline interleukin-2 on human and feline leukocytes.

M. Alegre, J. Takeda, A. Leff, 1995, Veterinary immunology and immunopathology.

The ATS journals' policy on image manipulation.

K. Adler, A. Leff, E. Abraham, 2008, Proceedings of the American Thoracic Society.

Regulation of adhesion of AML14.3D10 cells by surface clustering of β2‐integrin caused by ERK‐independent activation of cPLA2

S. Myou, K. Hamann, Yimin Qin, 2002, Immunology.

Changes in levels of mRNA encoding myosin heavy chain in porcine trachealis during ontogenesis.

R. Wiesner, R. Panettieri, A. Leff, 1993, American journal of respiratory cell and molecular biology.

Mechanical induction of group V phospholipase A(2) causes lung inflammation and acute lung injury.

A. Birukova, K. Birukov, A. Leff, 2013, American Journal of Physiology - Lung cellular and Molecular Physiology.

Augmentation of parasympathetic contraction in tracheal and bronchial airways by PGF2 alpha in situ.

A. Leff, N. Muñoz, J. Tallet, 1985, Journal of applied physiology.

Regulation of human eosinophil degranulation and activation by endogenous phospholipase A2.

M. Strek, A. Leff, S. Spaethe, 1993, The Journal of clinical investigation.

Therapeutic hypothermia cardioprotection in murine hemorrhagic shock/resuscitation differentially affects p38α/p38γ, Akt, and HspB1.

D. Beiser, S. Stern, A. Leff, 2011, The Journal of trauma.