D. Cipolla

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In vitro and ex vivo methods predict the enhanced lung residence time of liposomal ciprofloxacin formulations for nebulisation.

B. Forbes, M. Bebawy, P. Young, 2014, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Patient Focus and Regulatory Considerations for Inhalation Device Design: Report from the 2015 IPAC-RS/ISAM Workshop.

N. Roche, M. Dolovich, G. Scheuch, 2017, Journal of aerosol medicine and pulmonary drug delivery.

Inhaled nicotine replacement therapy

I. Gonda, D. Cipolla, 2015 .

Development of Liposomal Ciprofloxacin to Treat Lung Infections

I. Gonda, D. Cipolla, J. Blanchard, 2016, Pharmaceutics.

Emerging Opportunities for Inhaled Antibiotic Therapy

I. Gonda, D. Cipolla, J. Froehlich, 2015 .

Effective Treatment of Mycobacterium avium subsp. hominissuis and Mycobacterium abscessus Species Infections in Macrophages, Biofilm, and Mice by Using Liposomal Ciprofloxacin

L. Bermudez, I. Gonda, D. Cipolla, 2018, Antimicrobial Agents and Chemotherapy.

Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections

M. Corboz, Zhili Li, F. Leifer, 2021, Antimicrobial agents and chemotherapy.

Personalizing aerosol medicine: development of delivery systems tailored to the individual.

H. Chan, D. Farina, D. Cipolla, 2010, Therapeutic delivery.

Characterisation of cough evoked by inhaled treprostinil and treprostinil palmitil

M. Corboz, Zhili Li, D. Cipolla, 2020, ERJ Open Research.

Service Based Asynchronous Service Execution Environment

D. Cipolla, P. Renditore, F. Cosso, 2008 .

Recent Advances in Prodrug-based Nanoparticle Therapeutics.

F. Leifer, D. Cipolla, Kuan-Ju Chen, 2021, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Design and testing of aerosol delivery systems for reproducible clinical performance.

I. Gonda, D. Cipolla, C. Herst, 1998, Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine.

Will pulmonary drug delivery for systemic application ever fulfill its rich promise?

D. Cipolla, 2016, Expert opinion on drug delivery.

Pulmonary formulations: what remains to be done?

A. Hickey, H. Chan, D. Cipolla, 2010, Journal of aerosol medicine and pulmonary drug delivery.

AERx®Pulmonary Drug Delivery Systems

D. Cipolla, Eric Johansson, 2008 .

Prostanoid receptor subtypes involved in treprostinil-mediated vasodilation of rat pulmonary arteries and in treprostinil-mediated inhibition of collagen gene expression of human lung fibroblasts.

M. Corboz, D. Salvail, D. Cipolla, 2020, Prostaglandins & other lipid mediators.

Treprostinil palmitil inhibits the hemodynamic and histopathological changes in the pulmonary vasculature and heart in an animal model of pulmonary arterial hypertension.

M. Corboz, Zhili Li, D. Cipolla, 2021, European journal of pharmacology.

Treprostinil palmitil, an inhaled long-acting pulmonary vasodilator, does not show tachyphylaxis with daily dosing in rats.

M. Corboz, Zhili Li, D. Cipolla, 2020, Pulmonary pharmacology & therapeutics.

Changes in respiratory symptoms during 48-week treatment with ARD-3150 (inhaled liposomal ciprofloxacin) in bronchiectasis: results from the ORBIT-3 and -4 studies

A. O'donnell, C. Haworth, J. Chalmers, 2020, European Respiratory Journal.

Changes in respiratory symptoms during 48weeks treatment with ARD-3150 (inhaled liposomal ciprofloxacin) in bronchiectasis

A. O'donnell, C. Haworth, J. Chalmers, 2020 .

Current and Emerging Inhaled Therapies of Repositioned Drugs.

H. Chan, D. Cipolla, 2018, Advanced drug delivery reviews.

Sweetening Inhaled Antibiotic Treatment for Eradication of Chronic Respiratory Biofilm Infection

P. Young, H. Ong, D. Traini, 2018, Pharmaceutical Research.

Microbiological changes observed over 48 weeks of treatment with inhaled liposomal ciprofloxacin in individuals with non-cystic fibrosis bronchiectasis and chronic Pseudomonas aeruginosa lung infection.

J. Chalmers, I. Gonda, D. Cipolla, 2019, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Urgent Appeal from International Society for Aerosols in Medicine (ISAM) During COVID-19: Clinical Decision Makers and Governmental Agencies Should Consider the Inhaled Route of Administration: A Statement from the ISAM Regulatory and Standardization Issues Networking Group.

Jolyon P. Mitchell, H. Boushey, M. Dolovich, 2020, Journal of aerosol medicine and pulmonary drug delivery.

Delivery of Biologics to the Lung

I. Gonda, D. Cipolla, B. Otulana, 2001 .

Physical stability of dry powder inhaler formulations

Q. Zhou, D. Cipolla, Heejun Park, 2019, Expert opinion on drug delivery.

Inhaled antibiotics to treat lung infection.

H. Chan, D. Cipolla, 2013, Pharmaceutical patent analyst.

Formation of drug nanocrystals under nanoconfinement afforded by liposomes

T. Rades, D. Vanhecke, B. Rothen‐Rutishauser, 2016 .

Characterization of Aerosols of Human Recombinant Deoxyribonuclease I (rhDNase) Generated by Jet Nebulizers

S. Shire, I. Gonda, D. Cipolla, 1994, Pharmaceutical Research.

Coarse spray delivery to a localized region of the pulmonary airways for gene therapy.

R. Crystal, S. Shak, T. Sweeney, 2000, Human gene therapy.

Development and Characterization of an In Vitro Release Assay for Liposomal Ciprofloxacin for Inhalation

S. Eastman, T. Redelmeier, H. Chan, 2014 .

Production of solid lipid nanoparticle suspensions using supercritical fluid extraction of emulsions (SFEE) for pulmonary delivery using the AERx system.

B. Shekunov, P. Chattopadhyay, B. Boyd, 2007, Advanced drug delivery reviews.

Safety, Tolerability And Pharmacokinetics Of Novel Liposomal Ciprofloxacin Formulations For Inhalation In Healthy Volunteers And Non-Cystic Bronchiectasis Patients

P. Bruinenberg, D. Cipolla, D. Serisier, 2010, ATS 2010.

Assessment of aerosol delivery systems for recombinant human deoxyribonuclease

S. Shire, I. Gonda, D. Cipolla, 1994 .

Modifying the release properties of liposomes toward personalized medicine.

S. Eastman, T. Redelmeier, H. Chan, 2014, Journal of pharmaceutical sciences.

Solid State Characterization of Ciprofloxacin Liposome Nanocrystals.

T. Rades, B. Boyd, D. Cipolla, 2018, Molecular pharmaceutics.

Drug nanocrystallisation within liposomes

T. Rades, B. Boyd, D. Cipolla, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Direct Comparison of Standard Transmission Electron Microscopy and Cryogenic-TEM in Imaging Nanocrystals Inside Liposomes.

T. Rades, C. Nowell, B. Boyd, 2019, Molecular pharmaceutics.

Controlling the size and shape of liposomal ciprofloxacin nanocrystals by varying the lipid bilayer composition and drug to lipid ratio.

T. Rades, C. Nowell, B. Boyd, 2019, Journal of colloid and interface science.

Inhalation delivery systems with compliance and disease management capabilities.

S J Farr, I Gonda, I. Gonda, 1998, Journal of controlled release : official journal of the Controlled Release Society.

Inhaled, dual release liposomal ciprofloxacin in non-cystic fibrosis bronchiectasis (ORBIT-2): a randomised, double-blind, placebo-controlled trial

P. Thompson, D. Bilton, I. Gonda, 2013, Thorax.

Liposomal formulations for inhalation.

H. Chan, I. Gonda, D. Cipolla, 2013, Therapeutic delivery.

Storage stability of inhalable, controlled-release powder formulations of ciprofloxacin nanocrystal-containing liposomes.

H. Chan, D. Cipolla, Wei-Ren Ke, 2021, International journal of pharmaceutics.

Formation of ciprofloxacin nanocrystals within liposomes by spray drying for controlled release via inhalation.

H. Chan, D. Cipolla, P. Tang, 2020, International journal of pharmaceutics.

Ciprofloxacin nanocrystals liposomal powders for controlled drug release via inhalation.

H. Chan, D. Cipolla, Juanfang Ruan, 2019, International journal of pharmaceutics.

Aerosol Performance and Stability of Liposomes Containing Ciprofloxacin Nanocrystals

H. Chan, I. Gonda, D. Cipolla, 2015, Journal of aerosol medicine and pulmonary drug delivery.

Lipid-based carriers for pulmonary products: preclinical development and case studies in humans.

B. Shekunov, A. Hickey, D. Cipolla, 2014, Advanced drug delivery reviews.

Aerosol Performance and Long-Term Stability of Surfactant-Associated Liposomal Ciprofloxacin Formulations with Modified Encapsulation and Release Properties

H. Chan, I. Gonda, D. Cipolla, 2014, AAPS PharmSciTech.

Formulation technology to repurpose drugs for inhalation delivery

I. Gonda, D. Cipolla, 2011 .

Pharmacokinetics and antibacterial activity of inhaled liposomal ciprofloxacin hydrochloride in healthy volunteers and in cystic fibrosis (CF) patients

P. Bruinenberg, D. Cipolla, D. Serisier, 2009 .

Tuning Ciprofloxacin Release Profiles from Liposomally Encapsulated Nanocrystalline Drug

S. Eastman, T. Redelmeier, H. Chan, 2016, Pharmaceutical Research.

Development and Characterization of Treprostinil Palmitil Inhalation Aerosol for the Investigational Treatment of Pulmonary Arterial Hypertension

M. Corboz, Zhili Li, D. Cipolla, 2021, International journal of molecular sciences.

Liposomal Nanoparticles Control the Uptake of Ciprofloxacin Across Respiratory Epithelia

M. Bebawy, P. Young, H. Ong, 2012, Pharmaceutical Research.

Service-Oriented Architectures for Distributed Cooperative Instrumentation Grids

Anna Marina Scapolla, D. Cipolla, Andrea Bagnasco, 2009 .

Equivalence considerations for orally inhaled products for local action-ISAM/IPAC-RS European Workshop report.

David Cipolla, Svetlana Lyapustina, Dennis Sandell, 2012, Journal of aerosol medicine and pulmonary drug delivery.

Robustness of Aerosol Delivery of Amikacin Liposome Inhalation Suspension using the eFlow® Technology.

Zhili Li, D. Cipolla, W. Perkins, 2021, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Changes in respiratory symptoms during 48 weeks treatment with ARD-3150 (inhaled liposomal ciprofloxacin) in bronchiectasis: results from the ORBIT-3 and -4 studies

A. O'donnell, C. Haworth, J. Chalmers, 2020, Respiratory infections.

Comment on: inhaled antimicrobial therapy--barriers to effective treatment, by J. Weers, inhaled antimicrobial therapy - barriers to effective treatment, Adv. Drug Deliv. Rev. (2015), http://dx.doi.org/10.1016/j.addr.2014.08.013.

I. Gonda, D. Cipolla, J. Froehlich, 2015, Advanced drug delivery reviews.

113 Safety, tolerability and pharmacokinetics of novel liposomal ciprofloxacin formulations for inhalation in healthy volunteers (HV) and non-cystic fibrosis bronchiectasis (BE) patients

P. Bruinenberg, D. Cipolla, J. Blanchard, 2011 .

Nanoscale probing of liposome encapsulating drug nanocrystal using Atomic Force Microscopy-Infrared Spectroscopy.

H. Chan, W. Chrzanowski, D. Cipolla, 2020, Analytical chemistry.

Minimizing Variability of Cascade Impaction Measurements in Inhalers and Nebulizers

C. Quale, D. Cipolla, D. Christopher, 2008, AAPS PharmSciTech.

Reflections on Digital Health Tools for Respiratory Applications.

David Cipolla, Svetlana Lyapustina, Andy Dundon, 2020, Journal of aerosol medicine and pulmonary drug delivery.

Modeling of a spray drying method to produce ciprofloxacin nanocrystals inside the liposomes utilizing a response surface methodology: Box-Behnken experimental design.

H. Chan, D. Cipolla, Juanfang Ruan, 2021, International journal of pharmaceutics.

Aerosolized protein delivery in asthma: gamma camera analysis of regional deposition and perfusion.

G. Smaldone, D. Cipolla, J. Agosti, 2001, Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine.

Liposomal Nanoparticles Control the Uptake of Ciprofloxacin Across Respiratory Epithelia

M. Bebawy, P. Young, H. Ong, 2012, Pharmaceutical Research.

Sweetening Inhaled Antibiotic Treatment for Eradication of Chronic Respiratory Biofilm Infection

P. Young, H. Ong, D. Traini, 2018, Pharmaceutical Research.

In vitro and ex vivo methods predict the enhanced lung residence time of liposomal ciprofloxacin formulations for nebulisation.

B. Forbes, M. Bebawy, P. Young, 2014, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Safety, tolerability, pharmacokinetics and antimicrobial activity of inhaled liposomal ciprofloxacin formulations in humans

P. Bruinenberg, D. Cipolla, D. Serisier, 2010 .

Investigation of Protein-Surfactant Interactions by Analytical Ultracentrifugation and Electron Paramagnetic Resonance: The Use of Recombinant Human Tissue Factor as an Example

T. Randolph, S. Shire, L. Jones, 1999, Pharmaceutical Research.