S. Stein

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Fluorescamine: A Reagent for Assay of Amino Acids, Peptides, Proteins, and Primary Amines in the Picomole Range

Sidney Udenfriend, S. Udenfriend, S. Stein, 1972, Science.

Quantitative assessment of the cell penetrating properties of RI-Tat-9: evidence for a cell type-specific barrier at the plasma membrane of epithelial cells.

Yaming Su, P. Sinko, M. Leibowitz, 2004, Molecular pharmaceutics.

Doxycycline hydrogels with reversible disulfide crosslinks for dermal wound healing of mustard injuries.

P. Sinko, J. Laskin, A. Menjoge, 2011, Biomaterials.

Tumor-targeted bioconjugate based delivery of camptothecin: design, synthesis and in vitro evaluation.

W. Welsh, V. Kholodovych, P. Sinko, 2004, Journal of controlled release : official journal of the Controlled Release Society.

Microsequence analysis of peptides and proteins. IV. Structural studies on human leukocyte interferons.

S. Pestka, D. Hawke, J. Shively, 1982, Analytical biochemistry.

Hybridization properties of oligodeoxynucleotide pairs bridged by polyarginine peptides.

K. Breslauer, M. Leibowitz, S. Stein, 1996, Nucleic acids research.

Fluorometric assay of vasopressin and oxytocin: a general approach to the assay of peptides in tissues.

S. Udenfriend, K. Gruber, S. Stein, 1976, Proceedings of the National Academy of Sciences of the United States of America.

Protected thiol-polyethylene glycol: a new activated polymer for reversible protein modification.

S. Stein, C. Woghiren, B. Sharma, 1993, Bioconjugate chemistry.

Preparation and applications of peptide-oligonucleotide conjugates.

S. Stein, C. Tung, S. Stein, 2000, Bioconjugate chemistry.

Tumor-specific targeting of an anticancer drug delivery system by LHRH peptide.

S. Dharap, T. Minko, P. Sinko, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Tumor-targeted and activated bioconjugates for improved camptothecin delivery

P. Sinko, S. Stein, Pankaj V. Paranjpe, 2005, Anti-cancer drugs.

Amino Acid Analysis and Enzymatic Sequence Determination of Peptides by an Improved o-Phthaldialdehyde Precolumn Labeling Procedure

S. Pääbo, S. Stein, B. Jones, 1981 .

Active site of human liver aldehyde dehydrogenase.

Alexander D. MacKerell, R. Pietruszko, S. Stein, 1987, Biochemistry.

Conjugates bearing multiple formyl-methionyl peptides display enhanced binding to but not activation of phagocytic cells.

P. Sinko, M. Leibowitz, M. Chan, 2002, Bioconjugate chemistry.

Isolation and characterization of the opioid peptides from rat pituitary: beta-lipotropin.

S. Udenfriend, S. Stein, M. Rubinstein, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of pro-opiocortin, a precursor to opioid peptides and corticotropin.

S. Udenfriend, S. Stein, M. Rubinstein, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Separation of opioid peptides utilizing high performance liquid chromatography.

S. Udenfriend, R. Lewis, S. Stein, 2009, International journal of peptide and protein research.

An about 50,000-dalton protein in adrenal medulla: a common precursor of [Met]- and [Leu]enkephalin.

J. Rossier, S. Udenfriend, R. Lewis, 1980, Science.

[2] High-performance liquid chromatography and picomole-level detection of peptides and proteins

J. Moschera, S. Stein, 1981 .

Selection of continuous epitope sequences and their incorporation into poly(ethylene glycol)-peptide conjugates for use in serodiagnostic immunoassays: application to Lyme disease.

L. Sigal, S. Stein, M. Brunner, 2000, Biopolymers.

Purification and molecular characterization of human fibroblast interferon.

S. Pestka, J. Shively, J. Meienhofer, 1981, Archives of biochemistry and biophysics.

Purification and properties of a type beta transforming growth factor from bovine kidney.

A. Roberts, Y. Pan, J. M. Smith, 1983, Biochemistry.

Structure of two adrenal polypeptides containing multiple enkephalin sequences.

S. Udenfriend, J. Shively, R. Lewis, 1980, Archives of biochemistry and biophysics.

High-Performance Liquid Chromatography

S. Stein, 1982 .

Chapter 4 – Ultramicroanalysis of Peptides and Proteins by High-Performance Liquid Chromatography and Fluorescence Detection

S. Stein, 1981 .

BIOSYNTHESIS OF THE ENKEPHALINS: PRECURSORS AND INTERMEDIATES

S. Udenfriend, R. Lewis, J. Shively, 1980 .

Opioid hexapeptides and heptapeptides in adrenal medulla and brain possible implications on the biosynthesis of enkephalins.

J. Rossier, S. Udenfriend, R. Lewis, 1980, Archives of biochemistry and biophysics.

Analgesic activity of the naturally occurring heptapeptide [Met]enkephalin-Arg6-Phe7.

S. Udenfriend, R. Lewis, S. Stein, 1980, Proceedings of the National Academy of Sciences of the United States of America.

On βH-Leu5-Endorphin and Schizophrenia

S. Udenfriend, R. Lewis, B. I. Grosser, 1979 .

A re-evaluation of the opioid peptides present in the central nervous system utilizing microfluorometry

S. Udenfriend, S. Stein, M. Rubinstein, 1979 .

Binding assay for opioid peptides with neuroblastoma × glioma hybrid cells: Specificity of the receptor site

S. Udenfriend, S. Stein, M. Rubinstein, 1978, Brain Research.

An Improved Reverse Phase HPLC Separation and Postcolumn Detection of Amino Acids

S. Stein, N. Meltzer, G. Tous, 1987 .

Amino Acid Analysis With Postcolumn Fluorescent Derivatization

S. Stein, Y. Pan, 1986 .

Preparation of vitamin B6-conjugated peptides at the amino terminus and of vitamin B6-peptide-oligonucleotide conjugates.

S. Stein, T. Zhu, 1994, Bioconjugate chemistry.

Molecular targeting of drug delivery systems to ovarian cancer by BH3 and LHRH peptides.

S. Dharap, T. Minko, P. Sinko, 2003, Journal of controlled release : official journal of the Controlled Release Society.

Probable precursors of [Leu]enkephalin and [Met]enkephalin in adrenal medulla: peptides of 3-5 kilodaltons.

J. Rossier, S. Udenfriend, R. Lewis, 1980, Proceedings of the National Academy of Sciences of the United States of America.

High molecular weight opioid-containing proteins in striatum.

S. Udenfriend, R. Lewis, S. Stein, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Two adrenal opioid polypeptides: proposed intermediates in the processing of proenkephalin.

J. Shively, S. Undenfriend, S. Stein, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Molecular mimicry in Lyme disease: monoclonal antibody H9724 to B. burgdorferi flagellin specifically detects chaperonin-HSP60.

S. Williams, L. Sigal, S. Stein, 1993, Biochimica et biophysica acta.

Structure and chromosomal localization of the human and mouse muscle fructose-1,6-bisphosphatase genes.

T. Liehr, K. Eschrich, S. Stein, 2000, Gene.

Pharmacokinetic and pharmacodynamic evaluation of a novel in situ forming poly(ethylene glycol)-based hydrogel for the controlled delivery of the camptothecins.

P. Sinko, P. Chao, S. Stein, 2006, Journal of controlled release : official journal of the Controlled Release Society.

Purification of human fibroblast interferon by high-performance liquid chromatography.

S. Pestka, S. Stein, H. Friesen, 1981, Methods in enzymology.

Preparation and physical properties of conjugates of oligodeoxynucleotides with poly(delta)ornithine peptides.

K. Breslauer, S. Stein, C. Tung, 1993, Antisense research and development.

Oligonucleotide-poly-L-ornithine conjugates: binding to complementary DNA and RNA.

K. Breslauer, M. Leibowitz, S. Stein, 1993, Antisense research and development.

Design of peptide-acridine mimics of ribonuclease activity

M. Leibowitz, S. Stein, Z. Wei, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Preparation of oligonucleotide-peptide conjugates.

S. Stein, C. Tung, M. Rudolph, 1991, Bioconjugate chemistry.

Preparation of vitamin B6-peptide and vitamin B6-peptide-oligonucleotide conjugates.

S. Stein, T. Zhu, 1997, Methods in Enzymology.

Gel shift assay: demonstration of enhanced binding of oligo(delta)-L-ornithine-oligodeoxynucleotide conjugates to complementary DNA and RNA.

M. Leibowitz, S. Stein, S. Pooyan, 1996, Antisense & nucleic acid drug development.

Synthesis of oligoarginine-oligonucleotide conjugates and oligoarginine-bridged oligonucleotide pairs.

S. Stein, Z. Wei, C. Tung, 1994, Bioconjugate chemistry.

Purification and Analysis of Antigen-specific Suppressor Proteins derived from T-Cell

D. Webb, K. Wieder, J. Kapp, 1983 .

Purification and characterization of a monoclonal T-cell suppressor factor specific for poly(LGlu60LAla30LTyr10).

D. Webb, K. Wieder, J. Kapp, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Multi-well ELISA based on independent peptide antigens for antibody capture. Application to Lyme disease serodiagnosis.

L. Sigal, Z. Yu, S. Stein, 1996, Journal of immunological methods.

Specific G proteins mediate endothelin induced contraction.

K. Bitar, G. Omann, S. Stein, 1992, Life sciences.

Presence of an N-terminal polyhistidine tag facilitates stable expression of an otherwise unstable N-terminal domain of mouse tissue inhibitor of metalloproteinase-1 in Escherichia coli.

D. Denhardt, S. Stein, H. Lackland, 1998, Protein expression and purification.

A polyethylene glycol copolymer for carrying and releasing multiple copies of cysteine-containing peptides.

M. Leibowitz, S. Stein, S. Pooyan, 1998, Bioconjugate chemistry.

Purified membrane and soluble folate binding proteins from cultured KB cells have similar amino acid compositions and molecular weights but differ in fatty acid acylation.

B. Slomiany, S. Stein, S. Rothenberg, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Application of Fluorescent Techniques to the Study of Peptides

S. Stein, 1977 .

Characterization of the mouse liver fructose-1,6-bisphosphatase gene.

T. Liehr, K. Eschrich, S. Stein, 2001, Gene.

High-efficiency cation-exchange chromatography of polypeptides and polyamines in the nanomole range.

S. Udenfriend, A. Licht, K. Gruber, 1977, Journal of chromatography.

Isolation of the opioid heptapeptide Met-enkephalin [Arg6,Phe7] from bovine adrenal medullary granules and striatum.

J. Rossier, S. Udenfriend, R. Lewis, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Marked increases in large enkephalin-containing polypeptides in the rat adrenal gland following denervation

J. Rossier, S. Udenfriend, R. Lewis, 1981, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Studies with [35S]methionine indicate that the 22,000-dalton [Met]enkephalin-containing protein in chromaffin cells is a precursor of [Met]enkephalin.

J. Rossier, S. Udenfriend, R. Lewis, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Enkephalin biosynthetic pathway: proteins of 8000 and 14,000 daltons in bovine adrenal medulla.

S. Udenfriend, R. Lewis, S. Kimura, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Release of enkephalins and enkephalin-containing polypeptides from perfused beef adrenal glands.

S. Udenfriend, R. Lewis, D. Kilpatrick, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of recombinant human interleukin-2 with micromethods.

H. Lahm, S. Stein, Hans-Werner Lahm, 1985, Journal of chromatography.

Parathymosin alpha: a peptide from rat tissues with structural homology to prothymosin alpha.

B. Horecker, S. Stein, R. Blacher, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Protein and free amino acid content in preimplantation mouse embryos and in blastocysts under various culture conditions.

M. Sherman, M. Sellens, S. Stein, 1981, Journal of reproduction and fertility.

Multiple-Peptide Conjugates for Binding β-Amyloid Plaques of Alzheimer's Disease

P. Sinko, M. Leibowitz, Guobao Zhang, 2003 .

Enhancing the anticancer efficacy of camptothecin using biotinylated poly(ethyleneglycol) conjugates in sensitive and multidrug-resistant human ovarian carcinoma cells

T. Minko, P. Sinko, S. Stein, 2002, Cancer Chemotherapy and Pharmacology.

Pulmonary targeting microparticulate camptothecin delivery system: anticancer evaluation in a rat orthotopic lung cancer model

D. Laskin, S. S. Rajan, P. Sinko, 2010, Anti-cancer drugs.

Fluorometric assay of proteins in the nanogram range.

S. Udenfriend, S. Stein, W. Dairman, 1973, Archives of biochemistry and biophysics.

Targeting the Sodium-Dependent Multivitamin Transporter (SMVT) for Improving the Oral Absorption Properties of a Retro-Inverso Tat Nonapeptide

V. Ganapathy, P. Prasad, P. Sinko, 2001, Pharmaceutical Research.

Synthesis of poly(ethylene glycol)-based saquinavir prodrug conjugates and assessment of release and anti-HIV-1 bioactivity using a novel protease inhibition assay.

A. Rabson, P. Sinko, M. Leibowitz, 2004, Bioconjugate chemistry.

Design and evaluation of novel fast forming pilocarpine-loaded ocular hydrogels for sustained pharmacological response.

P. Sinko, Y. Singh, S. Stein, 2009, Journal of controlled release : official journal of the Controlled Release Society.

Nonenzymatic, Self‐Elimination Degradation Mechanism of Glutathione

P. Sinko, S. Stein, M. Deshmukh, 2009, Chemistry & biodiversity.

A hydrogel prepared by in situ cross-linking of a thiol-containing poly(ethylene glycol)-based copolymer: a new biomaterial for protein drug delivery.

P. Sinko, M. Leibowitz, Patrick J Sinko, 2003, Biomaterials.

Detection of fluorescamine-labeled amino acids, peptides, and other primary amines on thin-layer chromatograms

S. Udenfriend, K. Imai, S. Stein, 1974 .

Biodegradable poly(ethylene glycol) hydrogels based on a self-elimination degradation mechanism.

P. Sinko, Y. Singh, S. Stein, 2010, Biomaterials.

[64] Purification of human fibroblast interferon produced in the absence of serum by cibacron blue F3GA-agarose and high-performance liquid chromatography

J. Moschera, S. Stein, C. Kenny, 1981 .

Recombinant rat and murine immune interferons are phosphorylated at a single site, Ser132.

S. Pestka, T. Mariano, S. Stein, 1988, Journal of interferon research.

Primary structure of rat thymus prothymosin alpha.

B. Horecker, S. Stein, R. Blacher, 1985, Proceedings of the National Academy of Sciences of the United States of America.

A peptide-acridine conjugate with ribonucleolytic activity

Y. Ebright, S. Stein, C. Tung, 1992 .

Studies with 2-(butyldiphenylsiloxymethyl)-benzoyl protected oligodeoxyribonucleotides

Y. Ebright, S. Stein, C. Tung, 1993 .

Threshold size for optimal passive pulmonary targeting and retention of rigid microparticles in rats.

D. Laskin, P. Sinko, P. Chao, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Novel multi-component nanopharmaceuticals derived from poly(ethylene) glycol, retro-inverso-Tat nonapeptide and saquinavir demonstrate combined anti-HIV effects

A. Rabson, P. Sinko, M. Leibowitz, 2006, AIDS research and therapy.

Purification and biochemical analysis of antigen-specific suppressor factors isolated from T-cell hybridomas.

D. Webb, K. Wieder, J. Kapp, 1982, Current topics in microbiology and immunology.

[24] GAT antigen-specific suppressor factors

C. Turck, D. Webb, J. Kapp, 1985 .

Identification of the alpha subunit half-cystine specifically labeled by an affinity reagent for the acetylcholine receptor binding site.

A. Dwork, A. Karlin, P. Kao, 1984, The Journal of biological chemistry.

Resting state in normal and simian virus 40 transformed Chinese hamster lung cells.

S. Stein, R. Martin, 1976, Proceedings of the National Academy of Sciences of the United States of America.

Immunoglobulin M Capture Assay for Serologic Confirmation of Early Lyme Disease: Analysis of Immune Complexes with Biotinylated Borrelia burgdorferi Sonicate Enhanced with Flagellin Peptide Epitope

P. Mitchell, L. Sigal, S. Stein, 1998, Journal of Clinical Microbiology.

NH2-terminal amino acid sequence of human fibroblast interferon.

S. Pestka, J. Shively, S. Stein, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Design, Synthesis and Assay of Tetrapeptide‐Acridine Mimics of Ribonuclease

S. Stein, C. Tung, 1992, Annals of the New York Academy of Sciences.

Molecular Targeting of BCL2 and BCLXL Proteins by Synthetic BCL2 Homology 3 Domain Peptide Enhances the Efficacy of Chemotherapy

S. Dharap, T. Minko, S. Stein, 2006, Journal of Pharmacology and Experimental Therapeutics.

[63] Purification of human fibroblast interferon by high-performance liquid chromatography

S. Pestka, S. Stein, H. Friesen, 1981 .

Biodistribution and renal clearance of biocompatible lung targeted poly(ethylene glycol) (PEG) nanogel aggregates.

Debra L Laskin, Jeffrey D Laskin, D. Laskin, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Enhanced passive pulmonary targeting and retention of PEGylated rigid microparticles in rats.

D. Laskin, P. Sinko, P. Chao, 2010, International journal of pharmaceutics.

The primary structure of monkey pituitary growth hormone.

H. Lahm, S. Stein, C. Li, 1986, Archives of biochemistry and biophysics.

Noninvasive detection of passively targeted poly(ethylene glycol) nanocarriers in tumors.

P. Sinko, Y. Singh, S. Stein, 2012, Molecular pharmaceutics.

Multimeric peptide-based PEG nanocarriers with programmable elimination properties.

P. Sinko, S. Stein, Xiaoping Zhang, 2009, Biomaterials.

Putative enkephalin precursors in bovine adrenal medulla.

J. Rossier, S. Udenfriend, R. Lewis, 1979, Biochemical and biophysical research communications.

Novel monodisperse PEGtide dendrons: design, fabrication, and evaluation of mannose receptor-mediated macrophage targeting.

P. Sinko, Y. Singh, S. Stein, 2013, Bioconjugate chemistry.

Presentation of peptide antigens as albumin conjugates for use in detection of serum antibodies by enzyme-linked immunosorbent assay.

L. Sigal, Z. Yu, S. Stein, 1996, Bioconjugate chemistry.

Amino acid analysis of proteins and peptides at the picomole level: the fluorescamine amino acid analyzer.

S. Stein, L. Brink, 1981, Methods in Enzymology.

Purification to homogeneity of camel pituitary pro-opiocortin, the common precursor of opioid peptides and corticotropin.

S. Udenfriend, R. Lewis, S. Kimura, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Influence of Molecular Size on the Retention of Polymeric Nanocarrier Diagnostic Agents in Breast Ducts

S. Love, P. Sinko, Y. Singh, 2012, Pharmaceutical Research.

Discrimination of Primary Amines from Other Fluorescent Compounds in Biological Fluids

A. Licht, S. Stein, R. Bowman, 1981 .

Stabilization of DNA triple-helix formation by appended cationic peptides.

K. Breslauer, S. Stein, C. Tung, 1996, Bioconjugate chemistry.

Novel Detox Gel Depot Sequesters β-Amyloid Peptides in a Mouse Model of Alzheimer’s Disease

R. Sundaram, S. Stein, C. Kasinathan, 2012, International Journal of Peptide Research and Therapeutics.

Chromatographic Purification of Non-Ionic Methylphosphonate Oligodeoxyribonucleosides

J. Fausnaugh, Y. Ebright, S. Stein, 1988 .

Role for heme in mammalian protein synthesis: activation of an initiation factor.

C. Raffel, R. Kaempfer, S. Stein, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Preparation of Vitamin B6-Peptide and Vitamin B6-Peptide- Oligonucleotide Conjugates

S. Stein, T. Zhu, 1997 .

PHYSICS OF SLIGHTLY ENRICHED, NORMAL WATER LATTICES (THEORY AND EXPERIMENT)

R. L. Hellens, H. Arnold, S. Stein, 1958 .

Peritoneal Macrophage Uptake, Pharmacokinetics and Biodistribution of Macrophage-Targeted PEG-fMLF (N-Formyl-Methionyl-Leucyl-Phenylalanine) Nanocarriers for Improving HIV Drug Delivery

P. Sinko, M. Leibowitz, S. Stein, 2007, Pharmaceutical Research.

Pig brain contains cholecystokinin octapeptide and several cholecystokinin desoctapeptides.

R. Yalow, S. Stein, J. Eng, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Detoxification Depot for β -Amyloid Peptides

R. Sundaram, S. Stein, C. Kasinathan, 2008 .

An acridine amino acid derivative for use in Fmoc peptide synthesis.

S. Stein, C. Tung, T. Zhu, 1992, Peptide research.

Human prothymosin alpha: amino acid sequence and immunologic properties.

T. Komiyama, B. Horecker, S. Stein, 1986, Archives of Biochemistry and Biophysics.

Human prothymosin α: Amino acid sequence and immunologic properties

T. Komiyama, B. Horecker, S. Stein, 1986 .

Optimizing size and copy number for PEG-fMLF (N-formyl-methionyl-leucyl-phenylalanine) nanocarrier uptake by macrophages.

P. Sinko, M. Leibowitz, S. Stein, 2008, Bioconjugate chemistry.

Purification and molecular characterization of human fibroblast interferon.

S. Pestka, J. Shively, J. Meienhofer, 1981, Archives of biochemistry and biophysics.

Dual-specificity interaction of HIV-1 TAR RNA with Tat peptide-oligonucleotide conjugates.

M. Leibowitz, S. Stein, C. Tung, 1995, Bioconjugate chemistry.