G. Luheshi

N. Rothwell, K. Takeda, O. Touzani, 2003, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Attenuated fever in rats during late pregnancy is linked to suppressed interleukin‐6 production after localized inflammation with turpentine

Sylvain Williams, A. Aguilar-Valles, Y. Mistry, 2007, The Journal of physiology.

On the use of animal modeling to study maternal infection during pregnancy and prenatal cytokine exposure as risk factors for schizophrenia

P. Boksa, G. Luheshi, 2003, Clinical Neuroscience Research.

Leptin regulates leukocyte recruitment into the brain following systemic LPS-induced inflammation

S. Poole, G. Luheshi, W. Inoue, 2010, Molecular Psychiatry.

Effect of Obesity on the Acute Inflammatory Response in Pregnant and Cycling Female Rats

B. Woodside, G. Luheshi, J. Pohl, 2013, Journal of neuroendocrinology.

Named Series : Diet , Inflammation and the Brain Diet-induced weight gain produces a graded increase in behavioral responses to an acute immune challenge

B. Woodside, G. Luheshi, M. Sheppard, 2018 .

Acute starvation alters lipopolysaccharide-induced fever in leptin-dependent and -independent mechanisms in rats.

G. Luheshi, W. Inoue, 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

Interleukin-1 receptor antagonist as a modulator of gender differences in the febrile response to lipopolysaccharide in rats.

S. Poole, P. Boksa, H. Ashdown, 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

Sites of action of IL‐1 in the development of fever and cytokine responses to tissue inflammation in the rat

S. Hopkins, G. Luheshi, A. J. Miller, 1997, British journal of pharmacology.

Interleukin-1 receptor antagonist inhibits endotoxin fever and systemic interleukin-6 induction in the rat.

N. Rothwell, S. Hopkins, A. Miller, 1996, The American journal of physiology.

Circulating leptin mediates lipopolysaccharide‐induced anorexia and fever in rats

S. Poole, G. Luheshi, C. Sachot, 2004, The Journal of physiology.

Named Series : Diet , Inflammation and the Brain Leptin modulates the late fever response to LPS in diet-induced obese animals

B. Woodside, G. Luheshi, J. Pohl, 2014 .

Relationship between Interleukin‐1 and Interleukin‐1 Receptor Antagonist during the Development of Fever in the Rat a

N. Rothwell, S. Poole, G. Luheshi, 1998, Annals of the New York Academy of Sciences.

Fever and production of cytokines in response to repeated injections of muramyl dipeptide in guinea-pigs

J. Roth, B. Störr, E. Zeisberger, 1997, Pflügers Archiv.

Brain TNF: Damage limitation or damaged reputation?

N. Rothwell, G. Luheshi, 1996, Nature Medicine.

Vagotomy attenuates the behavioural but not the pyrogenic effects of interleukin-1 in rats

R. Dantzer, R. Bluthé, J. Konsman, 2000, Autonomic Neuroscience.

Circulating IL-6 contributes to peripheral LPS-induced mPGES-1 expression in the rat brain

G. Luheshi, K. Matsumura, C. Rummel, 2011, Brain Research Bulletin.

Circulating interleukin-6 induces fever through a STAT3-linked activation of COX-2 in the brain.

S. Poole, G. Luheshi, C. Rummel, 2006, American journal of physiology. Regulatory, integrative and comparative physiology.

Role of brain transmigrating neutrophils in depression-like behavior during systemic infection

B. Woodside, A. Aguilar-Valles, G. Luheshi, 2015, Molecular Psychiatry.

Acute brain cytokine responses after global birth hypoxia in the rat

P. Boksa, H. Ashdown, G. Luheshi, 2008, Journal of neuroscience research.

Local cytokine induction by LPS in the rat air pouch and its relationship to the febrile response.

N. Rothwell, S. Hopkins, A. Miller, 1997, The American journal of physiology.

MIP-1γ : molecular cloning, expression, and biological activities of a novel CC chemokine that is constitutively secreted in vivo

B. Beutler, A. Poltorak, I. Smirnova, 1995 .

The Role of the Vagus Nerve in Mediating the Long‐Term Anorectic Effects of Leptin

G. Luheshi, C. Rummel, A. Bristow, 2007, Journal of neuroendocrinology.

The vagus nerve mediates behavioural depression, but not fever, in response to peripheral immune signals; a functional anatomical analysis

R. Dantzer, R. Bluthé, J. Konsman, 2000, The European journal of neuroscience.

The viral mimic, polyinosinic:polycytidylic acid, induces fever in rats via an interleukin-1-dependent mechanism.

Stephen Kent, S. Poole, P. Boksa, 2004, American journal of physiology. Regulatory, integrative and comparative physiology.

Purinoceptor desensitization impairs but does not abolish the non-cholinergic motor transmission in rat isolated urinary bladder.

G. Luheshi, A. Zar, 1990, European journal of pharmacology.

Importance of brain IL-1 type II receptors in fever and thermogenesis in the rat.

N. Rothwell, S. Hopkins, G. Luheshi, 1993, The American journal of physiology.

Microglia along sex lines: From brain colonization, maturation and function, to implication in neurodevelopmental disorders.

M. Tremblay, G. Luheshi, Micaël Carrier, 2019, Seminars in cell & developmental biology.

Febrile response to tissue inflammation involves both peripheral and brain IL-1 and TNF-alpha in the rat.

N. Rothwell, A. Turnbull, S. Hopkins, 1997, The American journal of physiology.

Leptin and interleukin-6 alter the function of mesolimbic dopamine neurons in a rodent model of prenatal inflammation

A. Aguilar-Valles, S. Poole, C. Flores, 2012, Psychoneuroendocrinology.

Alterations in cognitive function and behavioral response to amphetamine induced by prenatal inflammation are dependent on the stage of pregnancy

A. Aguilar-Valles, G. Luheshi, 2011, Psychoneuroendocrinology.

Changes in hypothalamically mediated acute-phase inflammatory responses to lipopolysaccharide in diet-induced obese rats.

B. Woodside, G. Luheshi, J. Pohl, 2009, Endocrinology.

The Use of Cytokine Knockout Mice in Neuroimmunology

H. Boutin, E. Pinteaux, G. Luheshi, 2003 .

Prenatal infection leads to ASD-like behavior and altered synaptic pruning in the mouse offspring

Andrea L. Guzman, G. Luheshi, Suzanne van der Veldt, 2017, Brain, Behavior, and Immunity.

Prenatal maternal stress exposure and immune function in the offspring

S. King, D. Laplante, G. Luheshi, 2014, Stress.

Interleukin-10 modulates the synthesis of inflammatory mediators in the sensory circumventricular organs: implications for the regulation of fever and sickness behaviors

J. Roth, S. Poole, G. Luheshi, 2013, Journal of Neuroinflammation.

Central nervous action of interleukin‐1 mediates activation of limbic structures and behavioural depression in response to peripheral administration of bacterial lipopolysaccharide

R. Dantzer, J. Konsman, S. Poole, 2008, European Journal of Neuroscience.

Leptin modulates cell morphology and cytokine release in microglia

G. Luheshi, W. Inoue, B. Kan, 2010, Brain, Behavior, and Immunity.

Interleukin 1 in the brain: biology, pathology and therapeutic target

N. Rothwell, G. Luheshi, 2000, Trends in Neurosciences.

Interleukin-10 modulates the synthesis of inflammatory mediators in the sensory circumventricular organs: implications for the regulation of fever and sickness behaviors

J. Roth, S. Poole, G. Luheshi, 2013, Journal of Neuroinflammation.

Prenatal Inflammation-Induced Hypoferremia Alters Dopamine Function in the Adult Offspring in Rat: Relevance for Schizophrenia

A. Aguilar-Valles, C. Flores, G. Luheshi, 2010, PloS one.

Effects of prenatal immune activation on hippocampal neurogenesis in the rat

P. Boksa, H. Ashdown, G. Luheshi, 2009, Schizophrenia Research.

Chronic LPS exposure produces changes in intrinsic membrane properties and a sustained IL‐β‐dependent increase in GABAergic inhibition in hippocampal CA1 pyramidal neurons

M. Danik, Sylvain Williams, G. Luheshi, 2005, Hippocampus.

Maternal exposure to bacterial endotoxin during pregnancy enhances amphetamine-induced locomotion and startle responses in adult rat offspring.

R. Joober, P. Boksa, G. Luheshi, 2004, Journal of psychiatric research.

Tumor necrosis factor-alpha and fever after peripheral inflammation in the rat.

N. Rothwell, S. Kunkel, A. Turnbull, 1994, The American journal of physiology.

Effect of nifedipine on the contractile responses of the isolated rat bladder.

M. Zar, G. Luheshi, M. Iravani, 1990, The Journal of urology.

Obesity, adipokines and neuroinflammation

A. Aguilar-Valles, G. Luheshi, W. Inoue, 2015, Neuropharmacology.

Dark microglia: A new phenotype predominantly associated with pathological states

C. Limatola, M. Tremblay, D. Gomez-Nicola, 2016, Glia.

Leptin actions on food intake and body temperature are mediated by IL-1.

A. Loudon, N. Rothwell, G. Luheshi, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Maternal infection and fever during late gestation are associated with altered synaptic transmission in the hippocampus of juvenile offspring rats.

Sylvain Williams, G. Luheshi, Germaine C. Lowe, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

Effects of endogenous glucocorticoid secretion on the interleukin-6 response to bacterial endotoxin in pregnant and non-pregnant rats.

P. Boksa, G. Luheshi, Ke Cui, 2011, The Journal of endocrinology.

Altered expression of lipid metabolism and immune response genes in the frontal cortex of suicide completers.

A. Sequeira, G. Turecki, T. Klempan, 2010, Journal of affective disorders.

Interleukin (IL)-6 release and fever induced by a pre-formed pyrogenic factor (PFPF) derived from LPS-stimulated macrophages.

N. Rothwell, S. Hopkins, G. Luheshi, 2000, European cytokine network.

Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E

J. Lacaille, R. Nadon, N. Sonenberg, 2018, Nature Communications.

Inhibition of non-cholinergic motor transmission in isolated rat urinary-bladder by nifedipine

M. Zar, G. Luheshi, M. Iravani, 1988 .

Cholesterol content in brains of suicide completers.

E. Levy, A. Sequeira, G. Turecki, 2007, The international journal of neuropsychopharmacology.

Leptin is involved in age-dependent changes in response to systemic inflammation in the rat

J. Roth, T. Wenz, G. Luheshi, 2014, Brain, Behavior, and Immunity.

Cytokines as messengers of neuroimmune interactions

G. Luheshi, A. Dam, E. Hammond, 1996, Trends in Neurosciences.

Identification of a truncated IL-18Rβ mRNA: a putative regulator of IL-18 expressed in rat brain

N. Rothwell, S. Pickering-Brown, I. Kimber, 2003, Journal of Neuroimmunology.

Leptin induces interleukin‐1β release from rat microglial cells through a caspase 1 independent mechanism

N. Rothwell, E. Pinteaux, L. Schmidt, 2007, Journal of neurochemistry.

Prenatal maternal stress predicts reductions in CD4+ lymphocytes, increases in innate-derived cytokines, and a Th2 shift in adolescents: Project Ice Storm

S. King, D. Laplante, G. Luheshi, 2015, Physiology & Behavior.

Multiple mechanisms mediate antipyretic action of glucocorticoids.

N. Rothwell, S. Hopkins, G. Luheshi, 1995, The American journal of physiology.

IL-1beta induced changes in hypothalamic IL-1R1 and IL-1R2 mRNA expression in the rat.

N. Rothwell, G. Luheshi, L. Parker, 2000, Brain research. Molecular brain research.

IL-1 receptor antagonist inhibits the endotoxin-induced rise in plasma IL-6 in the rat.

N. Rothwell, S. Hopkins, G. Bate, 1994 .

Obesity‐ and Neuroinflammation‐Associated Mood and Cognitive Disorders

N. Castanon, S. Layé, G. Luheshi, 2015 .

Leptin and cytolines:Actions and interactions in fever and appetite control

G. Luheshi, 2001 .

Is programming of weight regulation immune to neonatal inflammation?

G. Luheshi, C. Rummel, 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

Leptin induces cyclooxygenase‐2 via an interaction with interleukin‐1β in the rat brain

Adrian F Bristow, S. Poole, G. Luheshi, 2006, The European journal of neuroscience.

Immune-to-brain signaling and central prostaglandin E2 synthesis in fasted rats with altered lipopolysaccharide-induced fever.

S. Poole, G. Luheshi, W. Inoue, 2008, American Journal of Physiology. Regulatory Integrative and Comparative Physiology.

Central nervous action of interleukin‐1 mediates activation of limbic structures and behavioural depression in response to peripheral administration of bacterial lipopolysaccharide

J. Konsman, G. Luheshi, C. Combe, 2008, The European journal of neuroscience.

The effects of dietary saturated fat on basal hypothalamic neuroinflammation in rats

B. Woodside, G. Luheshi, Tia Maric, 2014, Brain, Behavior, and Immunity.

Prenatal infection leads to ASD-like behavior and altered synaptic pruning in the mouse offspring

Andrea L. Guzman, G. Luheshi, Suzanne van der Veldt, 2017, Brain, Behavior, and Immunity.

Maternal infection and fever during late gestation are associated with altered synaptic transmission in the hippocampus of juvenile offspring rats.

Sylvain Williams, G. Luheshi, Germaine C. Lowe, 2008, American Journal of Physiology. Regulatory Integrative and Comparative Physiology.

The effect of streptozotocin‐induced diabetes on cholinergic motor transmission in the rat urinary bladder

M. Zar, G. Luheshi, M.A. Zar, 1991, British journal of pharmacology.

Acute brain cytokine responses after global birth hypoxia in the rat

P. Boksa, H. Ashdown, G. Luheshi, 2008, Journal of neuroscience research.