A. Lewis

发表

A chemical biology toolbox to study protein methyltransferases and epigenetic signaling

Jian Jin, Matthieu Schapira, Jennifer A. Ward, 2019, Nature Communications.

Phylogenetic Analysis of Polyomavirus Simian Virus 40 from Monkeys and Humans Reveals Genetic Variation

G. Fox, J. Butel, Z. Forsman, 2004, Journal of Virology.

E1A oncogene-induced sensitization of human tumor cells to innate immune defenses and chemotherapy-induced apoptosis in vitro and in vivo.

D. Ikle, A. Lewis, Tanya A. Miura, 2003, Cancer research.

A Mouse Strain Defective in Both T Cells and NK Cells Has Enhanced Sensitivity to Tumor Induction by Plasmid DNA Expressing Both Activated H-Ras and c-Myc

S. Hughes, J. Coffin, D. Blair, 2014, PloS one.

Development of a Neutralization Assay for Influenza Virus Using an Endpoint Assessment Based on Quantitative Reverse-Transcription PCR

K. Peden, B. Teferedegne, A. Lewis, 2013, PloS one.

A quantitative PCR assay for SV40 neutralization adaptable for high-throughput applications.

K. Peden, B. Teferedegne, A. Lewis, 2009, Journal of virological methods.

STAT3 pathway regulates lung-derived brain metastasis initiating cell capacity through miR-21 activation

I. Jurisica, M. Geletu, P. Lai, 2015, Oncotarget.

A novel canine kidney cell line model for the evaluation of neoplastic development: karyotype evolution associated with spontaneous immortalization and tumorigenicity

K. Peden, M. Breen, Rachael Thomas, 2015, Chromosome Research.

A Chemical Probe For Tudor Domain Protein Spin1 to Investigate Chromatin Functions

O. Fedorov, C. Bountra, C. Arrowsmith, 2019 .

Oncogenicity of simian virus 40 deletion mutants that induce altered 17-kilodalton t-proteins.

A. Lewis, R. Martin, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Chemical Instability and Promiscuity of Arylmethylidenepyrazolinone-Based MDMX Inhibitors

G. Wynne, T. Lundbäck, C. Bataille, 2018, ACS chemical biology.

Transformation of rat embryo cells by adenovirus type 1.

R. Huebner, A. Lewis, R. McAllister, 1969, Journal of General Virology.

SV40 in adenovirus vaccines and adenovirus-SV40 recombinants.

A. Lewis, 1998, Developments in biological standardization.

Characterization of hamster tumors induced by simian virus 40 small t deletion mutants as true histiocytic lymphomas.

M. Carbone, A. Levine, B. Matthews, 1989, Cancer research.

DNA virus‐transformed hamster cell – host effector cell interactions: Level of resistance to cytolysis correlated with tumorigenicity

A. Lewis, J. Hibbs, J. L. Cook, 1982, International journal of cancer.

Tumorigenicity of hamster and mouse cells transformed by adenovirus types 2 and 5 is not influenced by the level of class I major histocompatibility antigens expressed on the cells.

J. Coligan, H. Haddada, A. Levine, 1986, Proceedings of the National Academy of Sciences of the United States of America.

A new role for DNA virus early proteins in viral carcinogenesis.

A. Lewis, J. L. Cook, J. Cook, 1985, Science.

The adenovirus type 2-simian virus 40 hybrid virus Ad2+ND4 requires deletion variants to grow in monkey cells

H. Westphal, A. Lewis, 1983, Journal of virology.

The Adenovirus-SV40 Hybrid Viruses

A. Levine, A. Lewis, C. Patch, 1979 .

Mapping of Simian Virus 40 Early Functions on the Viral Chromosome

T. Kelly, P. Berg, P. Berg, 1973, Journal of virology.

Real-time, quantitative PCR assays for the detection of virus-specific DNA in samples with mixed populations of polyomaviruses.

K. Peden, L. Sirota, A. Lewis, 2006, Journal of virological methods.

Recovery of strains of the polyomavirus SV40 from rhesus monkey kidney cells dating from the 1950s to the early 1960s.

K. Peden, M. Laassri, K. Chumakov, 2008, Virology.

Responsiveness to basement membrane extract as a possible trait for tumorigenicity characterization

K. Peden, A. Lewis, Kathryn Phy, 2019, Vaccine: X.

Relationship of Adenovirus 2 Deoxyribonucleic Acid and Simian Virus 40 Deoxyribonucleic Acid in the Ad 2 + ND , Genome

M. Levin, M. Oxman, A. Lewis, 2003 .

Content and expression of integrated viral DNA in hamster cells transformed by nondefective adenovirus type 2- simian virus 40 hybrid viruses

A. Levine, L. Schnipper, A. Lewis, 1976, Journal of virology.

Analysis of pp60c-src protein kinase activity in hamster embryo cells transformed by simian virus 40, human adenoviruses, and bovine papillomavirus 1

M. Israel, J. Butel, S. Amini, 1986, Journal of virology.

Heterogeneity of the tumorigenic phenotype expressed by Madin-Darby canine kidney cells.

P. Snoy, K. Peden, B. Teferedegne, 2011, Comparative medicine.

Use of Nondefective Adenovirus-Simian Virus 40 Hybrids for Mapping the Simian Virus 40 Genome

T. Kelly, A. Lewis, 1973, Journal of virology.

A novel canine kidney cell line model for the evaluation of neoplastic development: karyotype evolution associated with spontaneous immortalization and tumorigenicity

K. Peden, M. Breen, B. Teferedegne, 2015, Chromosome Research.

Viral DNA sequences and gene products in hamster cells transformed by adenovirus type 2

C. Tibbetts, U. Pettersson, L. Philipson, 1978, Journal of virology.

Identification of a neutralization epitope in the VP1 capsid protein of SV40.

K. Peden, B. Teferedegne, A. Lewis, 2008, Virology.

Identification of a mutation in the SV40 capsid protein VP1 that influences plaque morphology, vacuolization, and receptor usage.

K. Peden, A. Lewis, Haruhiko Murata, 2008, Virology.

Simian virus 40 DNA replication, transcription, and antigen induction during infection with two adenovirus 2-SV40 hybrids that contain the entire SV40 genome

A. Levine, S. Siegel, A. Lewis, 1975, Journal of virology.

Driving adenovirus type 12-transformed BALB/c mouse cells to express high levels of class I major histocompatibility complex proteins enhances, rather than abrogates, their tumorigenicity

S. Soddu, A. Lewis, 1992, Journal of virology.

Failure-to-thrive syndrome associated with tumor formation by Madin-Darby canine kidney cells in newborn nude mice.

P. Snoy, K. Peden, B. Teferedegne, 2013, Comparative medicine.

Immunological surveillance against DNA-virus-transformed cells: correlations between natural killer cell cytolytic competence and tumor susceptibility of athymic rodents

A. Lewis, J. L. Cook, J. Cook, 1987, Journal of virology.

Host response to adenovirus 2-transformed hamster embryo cells.

A. Lewis, J. L. Cook, J. Cook, 1979, Cancer research.

Quantitative determination of the infectivity of the proviral DNA of a retrovirus in vitro: Evaluation of methods for DNA inactivation.

K. Peden, A. Lewis, Li Sheng-Fowler, 2009, Biologicals : journal of the International Association of Biological Standardization.

Nanomolar-Potency Small Molecule Inhibitor of STAT5 Protein

David E. Muench, X. Cheng, M. Minden, 2014, ACS medicinal chemistry letters.

Inhibiting aberrant signal transducer and activator of transcription protein activation with tetrapodal, small molecule Src homology 2 domain binders: promising agents against multiple myeloma.

S. Trudel, P. Spagnuolo, A. Schimmer, 2013, Journal of medicinal chemistry.

Developing an approach to evaluate the use of neoplastic cells as vaccine substrates.

A. Lewis, 2001, Developments in biologicals.

Resistance of simian virus 40-transformed hamster cells to the cytolytic effect of activated macrophages: a possible factor in species-specific viral oncogenicity.

A. Lewis, J. Hibbs, J. L. Cook, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Recovery of Mycoplasmas in the Study of Human Leukæmia and Other Malignancies

L. Hayflick, A. Girardi, N. Somerson, 1965, Nature.

Issues associated with residual cell-substrate DNA in viral vaccines.

K. Peden, A. Lewis, Li Sheng-Fowler, 2009, Biologicals : journal of the International Association of Biological Standardization.

A. Lewis, C. Kirkpatrick, J. L. Cook, 1979, Cancer research.

The interface between adenovirus-transformed cells and cellular immune response in the challenged host.

A. Lewis, J. Cook, 1984, Current topics in microbiology and immunology.

Spectrum of tumorigenic phenotypes among adenovirus 2-, adenovirus 12-, and simian virus 40-transformed Syrian hamster cells defined by host cellular immune-tumor cell interactions.

A. Lewis, J. Cook, 1982, Cancer research.

The implications of the different tumor-inducing capacities of adenovirus 2 and SV40 transformed hamster cells.

A. Lewis, C. Kirkpatrick, A. Rabson, 1981, Advances in experimental medicine and biology.

A relationship between SV40-transformed cell susceptibility to macrophage killing and tumor induction in rodents.

A. Lewis, J. Hibbs, J. Cook, 1981, Advances in experimental medicine and biology.

Rejection of adenovirus 2-transformed cell tumors and immune responsiveness in Syrian hamsters.

A. Lewis, C. Kirkpatrick, A. Rabson, 1979, Cancer research.

Differential NK cell and macrophage killing of hamster cells infected with nononcogenic or oncogenic adenovirus.

A. Lewis, J. Cook, 1984, Science.

Stimulation of pp60c‐src tyrosyl kinase activity in polyoma virus–infected mouse cells is closely associated with polyoma middle tumor antigen synthesis

M. Israel, J. Bolen, A. Lewis, 1985, Journal of cellular biochemistry.

The level of expression of adenovirus type 2 transforming genes governs sensitivity to nonspecific immune cytolysis and other phenotypic properties of adenovirus 2-simian virus 40-transformed cell hybrids

A. Levine, K. Akagi, A. Lewis, 1985, Molecular and cellular biology.

Control of Simian Virus 40 Gene Expression in Adenovirus-Simian Virus 40 Hybrid Viruses Synthesis of Hybrid Adenovirus 2-Simian Virus 40 RNA Molecules in Cells Infected with a Nondefective Adenovirus 2-Simian Virus 40 Hybrid Virus

M. Levin, M. Oxman, A. Lewis, 1974, Journal of virology.

Studies of Nondefective Adenovirus 2-Simian Virus 40 Hybrid Viruses. VI. Characterization of the DNA from Five Nondefective Hybrid Viruses

C. Crumpacker, A. Levine, L. Schnipper, 1973, Journal of virology.

Studies of Nondefective Adenovirus 2-Simian Virus 40 Hybrid Viruses IV. Characterization of the Simian Virus 40 Ribonucleic Acid Species Induced by Wild-Type Simian Virus 40 and by the Nondefective Hybrid Virus, Ad2+ND1

C. Crumpacker, M. Levin, A. Levine, 1971, Journal of virology.

Studies of Nondefective Adenovirus 2-Simian Virus 40 Hybrid Viruses Transformation of Hamster Kidney Cells by Adenovirus 2 and the Nondefective Hybrid Viruses

A. Levine, A. Lewis, A. Rabson, 1974, Journal of virology.

Assessment of potential miRNA biomarkers of VERO-cell tumorigenicity in a new line (AGMK1-9T7) of African green monkey kidney cells.

Daniel M. Rotroff, D. Rotroff, B. Teferedegne, 2017, Vaccine.

MicroRNAs as potential biomarkers for VERO cell tumorigenicity.

K. Peden, E. Dragunsky, K. Chumakov, 2014, Vaccine.

Complete Nucleotide Sequence of Polyomavirus SA12

J. Pipas, P. Cantalupo, K. Peden, 2005, Journal of Virology.

Oncogenicity of DNA in vivo: tumor induction with expression plasmids for activated H-ras and c-myc.

S. Hughes, J. Coffin, D. Blair, 2008, Biologicals : journal of the International Association of Biological Standardization.

Studies of hamster cells transformed by adenovirus 2 and the nondefective Ad2-SV40 hybrids.

A. Levine, L. Schnipper, A. Lewis, 1975, Cold Spring Harbor symposia on quantitative biology.

Downregulation of Waf1, C2, C3, and major histocompatibility complex class I loci within an 18‐cM region of chromosome 17 in adenovirus‐transformed mouse cells

K. Huppi, A. Lewis, D. Siwarski, 1997, Molecular carcinogenesis.

Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agent

Derek J. Wilson, P. Gunning, A. Lewis, 2016, Oncotarget.

Activated macrophage mediated cytotoxicity for transformed target cells.

A. Lewis, J. Hibbs, D. Granger, 1982, Advances in experimental medicine and biology.

Lymphocytic-Choriomeningitis Virus in Hamster Tumor: Spread to Hamsters and Humans

R. Huebner, H. Turner, A. Lewis, 1965, Science.

Patterns of microRNA Expression in Non-Human Primate Cells Correlate with Neoplastic Development In Vitro

M. Quiñones, K. Peden, B. Teferedegne, 2010, PloS one.

Expression of the adenovirus E1A oncogene during cell transformation is sufficient to induce susceptibility to lysis by host inflammatory cells.

H. Ruley, F. Graham, S. Pilder, 1986, Proceedings of the National Academy of Sciences of the United States of America.

The AGMK1-9T7 cell model of neoplasia: Evolution of DNA copy-number aberrations and miRNA expression during transition from normal to metastatic cancer cells

Daniel M. Rotroff, A. Motsinger-Reif, D. Rotroff, 2022, PloS one.

Assessing the tumorigenic phenotype of VERO cells in adult and newborn nude mice.

K. Peden, A. Lewis, B. Orrison, 2008, Biologicals : journal of the International Association of Biological Standardization.

Studies ofNondefective Adenovirus 2-Simian Virus 40Hybrid Viruses. VI.Characterization oftheDNA fromFiveNondefective Hybrid Viruses

L. Schnipper, A. Lewis, A. S. Levine, 1973 .

Adenovirus Type 2-Simian Virus 40 Hybrid Population: Evidence for a Hybrid Deoxyribonucleic Acid Molecule and the Absence of Adenovirus-Encapsidated Circular Simian Virus 40 Deoxyribonucleic Acid

C. Crumpacker, M. Levin, W. Wiese, 1970, Journal of virology.

In vivo evolution of adenovirus 2-transformed cell virulence associated with altered E1A gene function.

T. Klimkait, W. Doerfler, A. Lewis, 1988, Virology.

Adenovirus E1A gene induction of susceptibility to lysis by natural killer cells and activated macrophages in infected rodent cells

A. Lewis, T. Walker, D. May, 1987, Journal of virology.

Two adenovirus type 2-simian virus 40 hybrid populations that contain the entire SV40 genome differ in their ability to induce SV40 transplantation immunity in hamsters but not in mice

S. Tevethia, A. Lewis, 1976, Journal of virology.

Evaluating virus-transformed cell tumorigenicity.

D. Alling, S. Banks, S. Soddu, 1999, Journal of virological methods.

Developing Inhibitors of STAT3: Targeting Downstream of the Kinases for Treating Disease

Jisung Park, P. Lai, P. Gunning, 2015 .

A p53 mutation in exon 5 associated with adenovirus transformation

K. Huppi, A. Lewis, D. Siwarski, 1995, Molecular carcinogenesis.

Viral gene inhibition of class I major histocompatibility antigen expression: not a general mechanism governing the tumorigenicity of adenovirus type 2-, adenovirus type 12-, and simian virus 40-transformed Syrian hamster cells

J. Coligan, H. Haddada, M. Carbone, 1988, Journal of virology.

Identification of Bidentate Salicylic Acid Inhibitors of PTP1B.

M. Tremblay, P. Gunning, A. Lewis, 2015, ACS medicinal chemistry letters.

Plaque purification as a method to mitigate the risk of adventitious-agent contamination in influenza vaccine virus seeds.

K. Peden, A. Lewis, Haruhiko Murata, 2011, Vaccine.

STUDIES OF ADENOVIRUS-SV 40 HYBRID VIRUSES , IV . AN ADENOVIRUS TYPE 2 STRAIN CARRYING THE INFECTIOUS SV 40 GENOME

A. Lewis, W. Rowe, K. Prigge, 2003 .

A colinear map relating the simian virus 40 (SV40) DNA segments of six adenovirus-SV40 hybrids to the DNA fragments produced by restriction endonuclease cleavage of SV40 DNA.

T. N. Lee, T. Kelly, D. Nathans, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Squirrel Monkeys Support Replication of BK Virus More Efficiently than Simian Virus 40: an Animal Model for Human BK Virus Infection

M. Raffeld, G. Fahle, S. Fischer, 2005, Journal of Virology.

Strand orientation of SV40 transcription in cells infected by non-defective adenovirus 2-SV40 hybrid viruses.

G. Khoury, A. Levine, M. Oxman, 1973, Nature: New biology.

Studies ofNondefective Adenovirus 2-Simian Virus 40Hybrid Viruses III. BaseComposition, Molecular Weight, andConformation oftheAd2+ND1Genome

C. Crumpacker, M. Levin, A. Lewis, 1971 .

A chemical biology toolbox to study protein methyltransferases and epigenetic signaling

Jennifer A. Ward, P. Richardson, C. Arrowsmith, 2018, bioRxiv.

Biological activity of residual cell-substrate DNA.

K. Peden, A. Lewis, L. Sheng, 2006, Developments in biologicals.

E1A oncogene induction of cytolytic susceptibility eliminates sarcoma cell tumorigenicity.

B. Wilson, A. Lewis, T. Walker, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Studies ofNondefective Adenovirus 2-Simian Virus 40Hybrid Viruses IV.Characterization oftheSimian Virus40Ribonucleic AcidSpecies Induced byWild-Type Simian Virus40andbytheNondefective HybridVirus, Ad2+ND1

C. Crumpacker, M. Levin, A. Levine, 1971 .

Structure of two adenovirus-simian virus 40 hybrids which contain the entire SV40 genome.

T. Kelly, A. Levine, S. Siegel, 1974, Journal of molecular biology.

A defined-risks approach to the regulatory assessment of the use of neoplastic cells as substrates for viral vaccine manufacture.

K. Peden, A. Lewis, P. Krause, 2001, Developments in biologicals.

Distribution, frequency, and quantitative analysis of estrogen, progesterone, androgen, and glucocorticoid receptors in human breast cancer.

G. Hortobagyi, E. Gehan, D. Greenblatt, 1979, Cancer research.

Method for determining the extent and copy number of overlapping and nonoverlapping segments of integrated viral genomes

A. Levine, A. Lewis, J. Hauser, 1979, Journal of Virology.

Studies of Nondefective Adenovirus 2-Simian Virus 40 Hybrid Viruses IX. Template Topography in the Early Region of Simian Virus 40

A. Levine, A. Lewis, C. Patch, 1974, Journal of virology.

Induction of Cellular DNA Synthesis by the Nondefective Adenovirus 2-Simian Virus 40 Hybrid Viruses

A. Levine, L. Schnipper, A. Lewis, 1973, Journal of Virology.

Evidence for a transcription-control region of Simian virus 40 in the adenovirus 2--Simian virus 40 hybrid, Ad2+ND 1 .

A. Levine, A. Lewis, C. Patch, 1972, Proceedings of the National Academy of Sciences of the United States of America.

Driving Adenovirus Type12-Transformed BALB/cMouseCellsTo Express HighLevels ofClassIMajorHistocompatibili ty ComplexProteins Enhances, Rather Than Abrogates, TheirTumorigenicity

A. Lewis, 1992 .

Suppression of the simian virus 40 tumorigenic phenotype in hybrid cells formed from simian virus 40- and adenovirus 2-transformed hamster embryo cells.

A. Levine, A. Lewis, J. Hauser, 1983, Cancer research.

A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function.

O. Fedorov, C. Bountra, C. Arrowsmith, 2019, Journal of Medicinal Chemistry.

A quantitative PCR assay for SV40 neutralization adaptable for high-throughput applications.

K. Peden, B. Teferedegne, A. Lewis, 2009, Journal of Virological Methods.

Flow cytometric detection of DNA tumor virus nuclear oncogene products in unfixed cells: saponin FACS of viral oncogene products.

A. Lewis, L. Lantz, Y. Eyler, 1994, Journal of virological methods.