A. Marques

发表

Chemical Proteomic Analysis of Serine Hydrolase Activity in Niemann-Pick Type C Mouse Brain

B. Florea, M. van der Stelt, E. V. van Rooden, 2018, Front. Neurosci..

Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes

A. Kalsbeek, E. Hol, W. Kamphuis, 2015, PloS one.

The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1

A. Kalsbeek, R. Seeley, M. Tschöp, 2019, Diabetes.

Current methods to analyze lysosome morphology, positioning, motility and function

A. Galione, J. Luzio, C. Futter, 2022, Traffic.

Lysosomal storage disorders – challenges, concepts and avenues for therapy: beyond rare diseases

P. Saftig, A. Marques, A. R. Marques, 2019, Journal of Cell Science.

Lysosomal Storage Diseases. For Better or Worse: Adapting to Defective Lysosomal Glycosphingolipid Breakdown

R. Boot, J. Aerts, A. Marques, 2017 .

Human glucocerebrosidase mediates formation of xylosyl-cholesterol by β-xylosidase and transxylosidase reactions

M. Artola, N. Pannu, T. Cox, 2020, Journal of lipid research.

Simultaneous quantitation of sphingoid bases by UPLC-ESI-MS/MS with identical 13C-encoded internal standards.

G. A. van der Marel, A. Marques, H. Overkleeft, 2017, Clinica chimica acta; international journal of clinical chemistry.

The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation[S]

E. Maspero, J. Nelson, N. Zelcer, 2013, Journal of Lipid Research.

Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis

Mahmoud A. Bassal, R. Lüllmann-Rauch, P. Saftig, 2020, Autophagy.

Gaucher disease and Fabry disease: new markers and insights in pathophysiology for two distinct glycosphingolipidoses.

R. Boot, A. Marques, H. Overkleeft, 2014, Biochimica et biophysica acta.

Novel activity-based probes for broad-spectrum profiling of retaining β-exoglucosidases in situ and in vivo.

G. A. van der Marel, J. Jiang, M. Witte, 2012, Angewandte Chemie.

Glucosylated cholesterol in mammalian cells and tissues: formation and degradation by multiple cellular β-glucosidases[S]

S. Karlsson, N. Pannu, Y. Hirabayashi, 2016, Journal of Lipid Research.

Delay of EGF-Stimulated EGFR Degradation in Myotonic Dystrophy Type 1 (DM1)

M. Niso-Santano, J. M. Fuentes, A. Aiastui, 2022, Cells.

Accurate quantification of sphingosine-1-phosphate in normal and Fabry disease plasma, cells and tissues by LC-MS/MS with (13)C-encoded natural S1P as internal standard.

M. van Eijk, C. V. van Roomen, A. Marques, 2016, Clinica chimica acta; international journal of clinical chemistry.

Lyso-glycosphingolipid abnormalities in different murine models of lysosomal storage disorders.

C. V. van Roomen, A. Marques, R. Ottenhoff, 2016, Molecular genetics and metabolism.

Lysosomal glycosphingolipid catabolism by acid ceramidase: formation of glycosphingoid bases during deficiency of glycosidases

R. Boot, A. Marques, H. Overkleeft, 2016, FEBS letters.

GCase and LIMP2 Abnormalities in the Liver of Niemann Pick Type C Mice

M. van Eijk, N. Claessen, A. Marques, 2021, International journal of molecular sciences.

Cathepsin D: Analysis of its potential role as an amyloid beta degrading protease

P. Saftig, A. Tholey, Lisa Gallwitz, 2022, Neurobiology of Disease.

Lysosome (Dys)function in Atherosclerosis—A Big Weight on the Shoulders of a Small Organelle

A. Marques, O. Vieira, G. Machado-Oliveira, 2021, Frontiers in Cell and Developmental Biology.

Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice

C. D. De Zeeuw, N. Claessen, Y. Yildiz, 2015, PloS one.

A Specific Activity‐Based Probe to Monitor Family GH59 Galactosylceramidase, the Enzyme Deficient in Krabbe Disease

H. Overkleeft, B. Florea, T. Cox, 2017, Chembiochem : a European journal of chemical biology.

Application of fluorescent β-glucopyrano-syl-configured cyclophellitol-aziridines for simultaneous differential fluorescent labeling of β-glucosidases and β-galactosidases

B. Florea, R. Boot, J. Aerts, 2017 .

Cell Senescence, Multiple Organelle Dysfunction and Atherosclerosis

A. Marques, O. Vieira, G. Machado-Oliveira, 2020, Cells.

Lentiviral gene therapy using cellular promoters cures type 1 Gaucher disease in mice.

A. Schambach, S. Karlsson, M. Ehinger, 2015, Molecular therapy : the journal of the American Society of Gene Therapy.

A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution

A. Heck, L. Johannes, R. Desnick, 2023, Frontiers in Bioengineering and Biotechnology.

Gpnmb Is a Potential Marker for the Visceral Pathology in Niemann-Pick Type C Disease

M. van Eijk, N. Claessen, C. V. van Roomen, 2016, PloS one.

Cholesteryl hemiazelate identified in CVD patients causes in vitro and in vivo inflammation

M. A. Surma, J. Sampaio, K. Simons, 2023, bioRxiv.

Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models

S. Rose-John, P. Saftig, B. Winner, 2022, Autophagy.

Cathepsin D: Analysis of its potential role as an amyloid beta degrading protease

P. Saftig, A. Tholey, Lisa Gallwitz, 2022, Neurobiology of Disease.

Oxidized cholesteryl ester induces exocytosis of dysfunctional lysosomes in lipidotic macrophages

R. Puertollano, C. Futter, W. Vaz, 2023, Traffic.

Analysis of cathepsin B and cathepsin L treatment to clear toxic lysosomal protein aggregates in neuronal ceroid lipofuscinosis.

P. Saftig, U. Bartsch, Lisa Gallwitz, 2021, Biochimica et biophysica acta. Molecular basis of disease.