J. García-Sevilla

I. Martín-Guerrero, J. García-Sevilla, G. Rivero, 2016, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

Alpha 2-adrenoceptor subtypes in the human brain: a pharmacological delineation of [3H]RX-821002 binding to membranes and tissue sections.

Á. Pazos, J. García-Sevilla, L. Callado, 1996, European journal of pharmacology.

The subtype-selective α2-adrenoceptor antagonists BRL 44408 and ARC 239 also recognize 5-HT1A receptors in the rat brain

Á. Pazos, J. García-Sevilla, L. Callado, 1996 .

Autoradiographic Demonstration of Increased α2‐Adrenoceptor Agonist Binding Sites in the Hippocampus and Frontal Cortex of Depressed Suicide Victims

Á. Pazos, J. García-Sevilla, J. Meana, 1994, Journal of neurochemistry.

Pentobarbital-induced sleep upregulates the survival p-FADD/FADD ratio in mouse brain cortex

M. Álvaro-Bartolomé, J. García-Sevilla, G. Salort, 2019, European Neuropsychopharmacology.

Monoamine receptor agonists, acting preferentially at presynaptic autoreceptors and heteroreceptors, downregulate the cell fate adaptor FADD in rat brain cortex

J. García-Sevilla, M. García-Fuster, 2015, Neuropharmacology.

Regulation of hippocampal Fas receptor and death-inducing signaling complex after kainic acid treatment in mice

J. García-Sevilla, B. Keller, 2015, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Role of Multifunctional FADD (Fas-Associated Death Domain) Adaptor in Drug Addiction

M. Álvaro-Bartolomé, J. García-Sevilla, M. García-Fuster, 2012 .

Correlation of rat cortical Fas-associated death domain (FADD) protein phosphorylation with the severity of spontaneous morphine abstinence syndrome: role of α2-adrenoceptors and extracellular signal-regulated kinases

A. Miralles, J. García-Sevilla, A. Ramos-Miguel, 2011, Journal of psychopharmacology.

Regulation of Fas receptor/Fas‐asssociated protein with death domain apoptotic complex and associated signalling systems by cannabinoid receptors in the mouse brain

J. Manzanares, S. Esteban, O. Valverde, 2010, British journal of pharmacology.

Effects of anti-depressant treatments on FADD and p-FADD protein in rat brain cortex: enhanced anti-apoptotic p-FADD/FADD ratio after chronic desipramine and fluoxetine administration

J. García-Sevilla, M. García-Fuster, 2016, Psychopharmacology.

High-affinity binding of beta-carbolines to imidazoline I2B receptors and MAO-A in rat tissues: norharman blocks the effect of morphine withdrawal on DOPA/noradrenaline synthesis in the brain.

S. Esteban, A. Miralles, D. Moranta, 2005, European journal of pharmacology.

Functional coupling between adenosine A1 receptors and G-proteins in rat and postmortem human brain membranes determined with conventional guanosine-5′-O-(3-[35S]thio)triphosphate ([35S]GTPγS) binding or [35S]GTPγS/immunoprecipitation assay

I. Matsuoka, T. Ota, J. García-Sevilla, 2018, Purinergic Signalling.

Human adenosine deaminase as an allosteric modulator of human A1 adenosine receptor: abolishment of negative cooperativity for [3H](R)‐pia binding to the caudate nucleus

J. Mallol, C. Lluis, R. Franco, 2008, Journal of neurochemistry.

Human blood platelet protein map established by two‐dimensional polyacrylamide gel electrophoresis

D. Hochstrasser, L. Balant, J. Guimón, 1995, Electrophoresis.

Decreased Number and Immunoreactivity of I2‐Imidazoline Receptors in the Frontal Cortex of Suicide Victims fn1

D. Reis, P. Escribá, M. Sastre, 1995, Annals of the New York Academy of Sciences.

Alpha 2-adrenoceptors in the brain of depressed suicide victims.

Á. Pazos, J. García-Sevilla, J. Meana, 1992, Clinical neuropharmacology.

The effects of chronic imidazoline drug treatment on glial fibrillary acidic protein concentrations in rat brain

P. Escribá, G. Olmos, J. García-Sevilla, 1994, British journal of pharmacology.

Increasedα 2;-adrenoceptor density in the frontal cortex of depressed suicide victims

J. García-Sevilla, J. Meana, 2005, Journal of Neural Transmission.

Brain α2‐adrenoceptors in monoamine‐depleted rats: increased receptor density, G coupling proteins, receptor turnover and receptor mRNA

X. Busquets, A. Miralles, J. García-Sevilla, 2001, British journal of pharmacology.

Effect of intracerebroventricularly administered somatostatin on brain monoamine turnover

A. Carlsson, J. García-Sevilla, T. Magnusson, 1978, Brain Research.

Acute treatment with the cyclic antidepressant desipramine, but not fluoxetine, increases membrane-associated G protein-coupled receptor kinases 2/3 in rat brain

A. Miralles, J. García-Sevilla, V. Asensio, 2002, Neuropharmacology.

The alkylating agent EEDQ facilitates protease-mediated degradation of the human brain α 2A-adrenoceptor as revealed by a sequence-specific antibody

P. Escribá, J. García-Sevilla, A. Ozaita, 1999, Neuroscience Letters.

Molecular characterization and isolation of a 45-kilodalton imidazoline receptor protein from the rat brain.

D. Reis, P. Escribá, A. Miralles, 1995, Brain research. Molecular brain research.

Increased density of guanine nucleotide-binding proteins in the postmortem brains of heroin addicts.

P. Escribá, M. Sastre, J. García-Sevilla, 1994, Archives of general psychiatry.

Effects of enkephalins and two enzyme resistant analogues on monoamine synthesis and metabolism in rat brain

A. Carlsson, J. García-Sevilla, T. Magnusson, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Imidazoline Receptors and Human Brain Disorders a

J. Guimón, P. Escribá, J. García-Sevilla, 1999, Annals of the New York Academy of Sciences.

Imidazoline receptor proteins in brains of patients with Alzheimer's disease

C. Bouras, J. Guimón, P. Escribá, 1998, Neuroscience Letters.

Downregulation of Neuronal cdk5/p35 in Opioid Addicts and Opiate-Treated Rats: Relation to Neurofilament Phosphorylation

J. Guimón, J. García-Sevilla, R. Harpe, 2003, Neuropsychopharmacology.

Modulation of immunoreactive protein kinase C-alpha and beta isoforms and G proteins by acute and chronic treatments with morphine and other opiate drugs in rat brain.

X. Busquets, J. García-Sevilla, P. Ventayol, 1997, Naunyn-Schmiedeberg's archives of pharmacology.

Selective Increase of α2A‐Adrenoceptor Agonist Binding Sites in Brains of Depressed Suicide Victims

Á. Pazos, M. Sastre, J. García-Sevilla, 1998, Journal of neurochemistry.

The Platelet α2-Adrenoceptor as a Potential Biological Marker in Depression

J. García-Sevilla, 1989, British Journal of Psychiatry.

Effects of the alkylating agent EEDQ on regulatory G proteins and recovery of agonist and antagonist alpha2-adrenoceptor binding sites in rat brain.

P. Escribá, A. Miralles, J. García-Sevilla, 1998, European journal of pharmacology.

Naloxone-precipitated withdrawal in morphine-dependent rats increases the expression of alpha 2a-adrenoceptor mRNA in brain.

X. Busquets, J. García-Sevilla, P. Ventayol, 1997, Brain research. Molecular brain research.

Spontaneous Withdrawal from Long‐Term Treatment with Morphine Accelerates the Turnover of α2‐Adrenoceptors in the Rat Brain: Up‐Regulation of Receptors Associated with Increased Receptor Appearance

J. García-Sevilla, A. Gabilondo, 1995, Journal of neurochemistry.

Density of alpha-2A adrenoceptors and Gi proteins in the human brain: ratio of high-affinity agonist sites to antagonist sites and effect of age.

M. Sastre, J. García-Sevilla, 1994, The Journal of pharmacology and experimental therapeutics.

Acceleration by chronic treatment with clorgyline of the turnover of brain α2‐adrenoceptors in normotensive but not in spontaneously hypertensive rats

A. Miralles, J. García-Sevilla, C. Ribas, 1993, British journal of pharmacology.

Long term treatment with desipramine increases the turnover of alpha 2-adrenoceptors in the rat brain.

J. García-Sevilla, F. Barturen, 1992, Molecular pharmacology.

Regulation of the extrinsic and intrinsic apoptotic pathways in the prefrontal cortex of short- and long-term human opiate abusers

J. García-Sevilla, G. Rivero, J. Meana, 2008, Neuroscience.

α2-Adrenoceptors and Associated Functional Responses in Endogenous Depression

J. García-Sevilla, 1989 .

Uncoupling of the platelet alpha 2-adrenoceptor adenylate cyclase system by N-ethylmaleimide and the resulting effect on receptor density and sensitivity.

J. García-Sevilla, M. Giralt, P. Areso, 1988, European journal of pharmacology.

α2-Adrenoreceptors in rat brain are decreased after long-term tricyclic antidepressant drug treatment

J. García-Sevilla, P. J. Hollingsworth, Charles B. Smith, 1981, Brain Research.

Increased mRNA expression of alpha2A-adrenoceptors, serotonin receptors and mu-opioid receptors in the brains of suicide victims.

P. Escribá, J. García-Sevilla, A. Ozaita, 2004, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.

Regulation of GRK 2 and 6, beta-arrestin-2 and associated proteins in the prefrontal cortex of drug-free and antidepressant drug-treated subjects with major depression.

J. Guimón, P. Huguelet, J. García-Sevilla, 2003, Brain research. Molecular brain research.

Regulation of G Protein‐Coupled Receptor Kinase 2 in Brains of Opiate‐Treated Rats and Human Opiate Addicts

P. Escribá, C. Murga, J. García-Sevilla, 1998, Journal of neurochemistry.

Decreased immunodensities of μ-opioid receptors, receptor kinases GRK 2/6 and β-arrestin-2 in postmortem brains of opiate addicts

J. García-Sevilla, R. Harpe, M. Ferrer-Alcón, 2004 .

Platelet alpha2 adrenoreceptors are decreased in number after antidepressant therapy

A. Zis, J. García-Sevilla, P. J. Hollingsworth, 1983, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Angiotensin II facilitates the potassium-evoked release of 3H-noradrenaline from the rabbit hypothalamus.

M. Dubocovich, J. García-Sevilla, S. Z. Langer, 1979, European journal of pharmacology.

Immunodetection and subcellular distribution of imidazoline receptor proteins with three antibodies in mouse and human brains: Effects of treatments with I1- and I2-imidazoline drugs

J. García-Sevilla, B. Keller, 2015, Journal of psychopharmacology.

Chronic treatment with selective I2-imidazoline receptor ligands decreases the content of pro-apoptotic markers in rat brain

A. Miralles, J. García-Sevilla, C. Garau, 2013, Journal of psychopharmacology.

PDFlib PLOP: PDF Linearization, Optimization, Protection Page inserted by evaluation version www.pdflib.com – sales@pdflib.com 12-Imidazoline Receptors in the Healthy and Pathologic Human Brain"

P. Escribá, A. Miralles, G. Olmos, 2008 .

Activation of I2‐imidazoline receptors enhances supraspinal morphine analgesia in mice: a model to detect agonist and antagonist activities at these receptors

G. Olmos, J. García-Sevilla, P. Sánchez-Blázquez, 2000, British journal of pharmacology.

Immunodetection and quantitation of imidazoline receptor proteins in platelets of patients with major depression and in brains of suicide victims.

D. Reis, J. Guimón, P. Escribá, 1996, Archives of general psychiatry.

Pharmacological modulation of immunoreactive imidazoline receptor proteins in rat brain: relationship with non‐adrenoceptor [3H]‐idazoxan binding sites

P. Escribá, G. Olmos, M. Sastre, 1996, British journal of pharmacology.

LSL 60101, a selective ligand for imidazoline I2 receptors, on glial fibrillary acidic protein concentration.

P. Escribá, G. Olmos, J. García-Sevilla, 1995, European journal of pharmacology.

Chronic Imidazoline Drug Treatment Increases the Immunoreactivity of Glial Fibrillary Acidic Protein in Rat Brain

G. Olmos, J. García-Sevilla, R. Alemany, 1995, Annals of the New York Academy of Sciences.

I2‐Imidazoline Receptors in the Healthy and Pathologic Human Brain fn1

P. Escribá, A. Miralles, G. Olmos, 1995, Annals of the New York Academy of Sciences.

Immunodetection of putative imidazoline receptor proteins in the human and rat brain and other tissues

D. Reis, P. Escribá, M. Sastre, 1994, Neuroscience Letters.

Effects of I2-imidazoline receptor (IR) alkylating BU99006 in the mouse brain: Upregulation of nischarin/I1-IR and μ-opioid receptor proteins and modulation of associated signalling pathways

J. García-Sevilla, B. Keller, 2017, Neurochemistry International.

Inhibitory effects of imidazoline receptor ligands on basal and kainic acid-induced neurotoxic signalling in mice

J. García-Sevilla, B. Keller, 2016, Journal of psychopharmacology.

Pharmacological and molecular discrimination of brain I2-imidazoline receptor subtypes

G. Olmos, J. García-Sevilla, R. Alemany, 1996, Naunyn-Schmiedeberg's Archives of Pharmacology.

Labelling of I2B-imidazoline receptors by [3H]2-(2-benzofuranyl)-2-imidazoline (2-BFI) in rat brain and liver: characterization, regulation and relation to monoamine oxidase enzymes

G. Olmos, J. García-Sevilla, R. Alemany, 1997, Naunyn-Schmiedeberg's Archives of Pharmacology.

The effects of phenelzine and other monoamine oxidase inhibitor antidepressants on brain and liver I2 imidazoline‐preferring receptors

G. Olmos, J. García-Sevilla, R. Alemany, 1995, British journal of pharmacology.

Neuroprotective Effects of a Structurally New Family of High Affinity Imidazoline I2 Receptor Ligands.

C. Escolano, J. García-Sevilla, L. Callado, 2017, ACS chemical neuroscience.

Densities of I2‐Imidazoline Receptors, Imidazoline Receptor Proteins, and MAO‐B Sites in Human Gliomas and Pituitary Adenomas a

P. Escribá, A. Ozaita, J. García-Sevilla, 1999, Annals of the New York Academy of Sciences.

Inhibition of monoamine oxidase A and B activities by imidazol(ine)/guanidine drugs, nature of the interaction and distinction from I2‐imidazoline receptors in rat liver

G. Olmos, M. Unzeta, J. García-Sevilla, 1997, British journal of pharmacology.

Effects of Gαi2 and Gαz protein knockdown on alpha2A-adrenergic and cannabinoid CB1 receptor regulation of MEK-ERK and FADD pathways in mouse cerebral cortex

J. García-Sevilla, P. Sánchez-Blázquez, A. Ramos-Miguel, 2021, Pharmacological Reports.

Activation and desensitization of presynaptic α2‐adrenoceptors after inhibition of neuronal uptake by antidepressant drugs in the rat vas deferens

J. Zubieta, J. García-Sevilla, J. Zubieta, 1986, British journal of pharmacology.

Pharmacologic and Molecular Discrimination of I2‐Imidazoline Receptor Subtypes a

G. Olmos, J. García-Sevilla, M. A. Boronat, 1999, Annals of the New York Academy of Sciences.

Chronic Treatment with Phenelzine and Other Irreversible Monoamine Oxidase Inhibitors Downregulates I2‐Imidazoline Receptors in the Brain and Liver fn1

G. Olmos, J. García-Sevilla, R. Alemany, 1995, Annals of the New York Academy of Sciences.

Differential Effects of the Alkylating Agent N‐Ethoxycarbonyl‐2‐Ethoxy‐1,2‐Dihydroquinoline on Brain α2‐Adrenoceptors and I2‐Imidazoline Sites In Vitro and In Vivo

A. Miralles, G. Olmos, J. García-Sevilla, 1993, Journal of neurochemistry.

Discrimination and pharmacological characterization of I2-imidazoline sites with [3H]idazoxan and alpha-2 adrenoceptors with [3H]RX821002 (2-methoxy idazoxan) in the human and rat brains.

A. Miralles, G. Olmos, M. Sastre, 1993, The Journal of pharmacology and experimental therapeutics.

Characterization of brain imidazoline receptors in normotensive and hypertensive rats: differential regulation by chronic imidazoline drug treatment.

A. Miralles, G. Olmos, J. García-Sevilla, 1992, The Journal of pharmacology and experimental therapeutics.

Densities of I2-imidazoline receptors, α 2-adrenoceptors and monoamine oxidase B in brains of suicide victims

M. Sastre, J. García-Sevilla, 1997, Neurochemistry International.

The α 2-adrenoceptor antagonist idazoxan is an agonist at 5-HT1A autoreceptors modulating serotonin synthesis in the rat brain in vivo

S. Esteban, J. García-Sevilla, J. Lladó, 1996, Neuroscience Letters.

Imidazoli(di)ne compounds interact with the phencyclidine site of NMDA receptors in the rat brain.

G. Olmos, J. García-Sevilla, J. Ribera, 1996, European journal of pharmacology.

Age-dependent increases of immunoreactive imidazoline receptors in the human brain: possible association of a 29 30 kDa protein with the I2-imidazoline receptor identified by [3H]idazoxan

P. Escribá, M. Sastre, J. García-Sevilla, 1995, Neuroscience Letters.

Exploring the antidepressant-like potential of the selective I2-imidazoline receptor ligand LSL 60101 in adult male rats.

J. García-Sevilla, M. García-Fuster, E. Hernández-Hernández, 2020, Pharmacological reports : PR.

In Vivo Effects of the I2‐Alkylating Agent BU99006 on the Immunodensity of Imidazoline Receptor Proteins in the Mouse Brain

J. García-Sevilla, M. Ferrer-Alcón, M. Ferrer‐Alcón, 2003, Annals of the New York Academy of Sciences.

Effects of imidazoline receptor ligands on monoamine synthesis in the rat brain in vivo

S. Esteban, J. García-Sevilla, A. Sastre-Coll, 1999, Naunyn-Schmiedeberg's Archives of Pharmacology.

Density of Imidazoline Receptors in Platelets of Euthymic Patients with Bipolar Affective Disorder and in Brains of Lithium-Treated Rats

J. Guimón, P. Escribá, A. Ozaita, 1998, Biological Psychiatry.

Platelet imidazoline receptors and regulatory G proteins in patients with major depression

J. Guimón, P. Escribá, X. Busquets, 1996, Neuroreport.

Decreased density of I2- imidazoline receptors in the postmortem brains of heroin addicts

M. Sastre, J. García-Sevilla, P. Ventayol, 1996, Neuroreport.

Nature of neuronal uptake and noradrenaline--adrenaline effects in the isolated rat vas deferens.

A. Badía, J. García-Sevilla, J. Laporte, 1975, European journal of pharmacology.

Regulation of immunolabelled μ-opioid receptors and protein kinase C-α and ζ isoforms in the frontal cortex of human opiate addicts

J. Guimón, X. Busquets, J. García-Sevilla, 1997, Neuroscience Letters.

Fundamental features of receptor-mediated Gαi/o activation in human prefrontal cortical membranes: A postmortem study

J. García-Sevilla, Y. Odagaki, L. Callado, 2020, Brain Research.

Ethanol desensitizes cannabinoid CB1 receptors modulating monoamine synthesis in the rat brain in vivo

S. Esteban, D. Moranta, J. García-Sevilla, 2006, Neuroscience Letters.

Brain RGS4 and RGS10 protein expression in schizophrenia and depression. Effect of drug treatment

J. García-Sevilla, B. Morentin, G. Rivero, 2013, Psychopharmacology.

Characterization of regulators of G-protein signaling RGS4 and RGS10 proteins in the postmortem human brain

J. García-Sevilla, B. Morentin, G. Rivero, 2010, Neurochemistry International.

The imidazoline receptor ligand 2-(2-benzofuranyl)-2-imidazoline is a dopamine-releasing agent in the rat striatum in vivo

S. Esteban, A. Miralles, J. García-Sevilla, 2001, Neuroscience Letters.

Acute, chronic and withdrawal effects of the cannabinoid receptor agonist WIN55212‐2 on the sequential activation of MAPK/Raf‐MEK‐ERK signaling in the rat cerebral frontal cortex: Short‐term regulation by intrinsic and extrinsic pathways

S. Esteban, D. Moranta, J. García-Sevilla, 2007, Journal of neuroscience research.

Bicyclic -iminophosphonates as highly affinity imidazoline I2 receptor ligands for Alzheimer's Disease.

F. J. Luque, P. Pérez-Lozano, L. Naesens, 2020, Journal of medicinal chemistry.

Effects of Opiate Drugs on Fas-Associated Protein with Death Domain (FADD) and Effector Caspases in the Rat Brain: Regulation by the ERK1/2 MAP Kinase Pathway

A. Miralles, J. García-Sevilla, M. García-Fuster, 2007, Neuropsychopharmacology.

α2 Autoreceptor-mediated modulation of tyrosine hydroxylase activity in noradrenergic regions of the rat brain in vivo

J. García-Sevilla, F. Pi, 1992, Naunyn-Schmiedeberg's Archives of Pharmacology.

Acute and chronic effects of reserpine on biochemical and functional parameters of central and peripheral α2-adrenoceptors

A. Miralles, G. Olmos, J. García-Sevilla, 1993 .

Acute and chronic effects of cholinesterase inhibitors and pilocarpine on the density and sensitivity of central and peripheral α2-adrenoceptors

A. Miralles, G. Olmos, J. García-Sevilla, 1993 .

Acute and long-term regulation of brain alpha 2-adrenoceptors after manipulation of noradrenergic transmission in the rat.

J. García-Sevilla, M. Giralt, 1989, European journal of pharmacology.

Effects of cyanamide on body weight and brain monoamines and metabolites in rats.

R. Obach, J. García-Sevilla, À. Menargues, 1986, European journal of pharmacology.

Role of lipid polymorphism in G protein-membrane interactions: nonlamellar-prone phospholipids and peripheral protein binding to membranes.

P. Escribá, A. Miralles, A. Ozaita, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Imidazoline Receptor System: The Past, the Present, and the Future

A. Hudson, P. Bousquet, J. García-Sevilla, 2020, Pharmacological Reviews.

Alpha 2-adrenoreceptors on human platelets: selective labelling by [3H]clonidine and [3H]yohimbine and competitive inhibition by antidepressant drugs.

J. García-Sevilla, P. J. Hollingsworth, C. B. Smnith, 1981, European journal of pharmacology.

Deglycosylation of Fas receptor and chronic morphine treatment up-regulate high molecular mass Fas aggregates in the rat brain.

A. Miralles, J. García-Sevilla, M. García-Fuster, 2004, European journal of pharmacology.

Modulation of Fas receptor proteins and dynamin during opiate addiction and induction of opiate withdrawal in rat brain

A. Miralles, J. García-Sevilla, M. García-Fuster, 2003, Naunyn-Schmiedeberg's Archives of Pharmacology.

Neurotransmitter receptor-mediated activation of G-proteins in brains of suicide victims with mood disorders: selective supersensitivity of α2A-adrenoceptors

J. Guimón, J. González-Maeso, J. García-Sevilla, 2002, Molecular Psychiatry.

Brain RGS4 and RGS10 protein expression in schizophrenia and depression. Effect of drug treatment

J. García-Sevilla, B. Morentin, G. Rivero, 2012, Psychopharmacology.

α2-autoreceptors and α2-heteroreceptors modulating tyrosine and tryptophan hydroxylase activity in the rat brain in vivo: an investigation into the α2-adrenoceptor subtypes

S. Esteban, J. García-Sevilla, J. Lladó, 1996, Naunyn-Schmiedeberg's Archives of Pharmacology.

Activation anddesensitization ofpresynaptic a adrenoceptors after inhibition ofneuronal uptake by antidepressant drugs intheratvasdeferens

J. Zubieta, J. García-Sevilla, 1986 .

Modulation by antidepressant drugs of CNS postsynaptic α2-adrenoceptors mediating mydriasis in the rat

J. García-Sevilla, À. Menargues, R. Obach, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Platelet alpha 2-adrenergic receptors in major depressive disorder. Binding of tritiated clonidine before and after tricyclic antidepressant drug treatment.

A. Zis, J. Greden, C. Smith, 1981, Archives of general psychiatry.

Comparative study of cumulative and non-cumulative dose-response curves for noradrenaline and adrenaline in the isolated rat vas deferens.

J. García-Sevilla, S. Erill, 1974, European journal of pharmacology.

Biochemical and functional evidence of supersensitive platelet alpha 2-adrenoceptors in major affective disorder. Effect of long-term lithium carbonate treatment.

J. Guimón, J. García-Sevilla, P. García-Vallejo, 1986, Archives of general psychiatry.

Modulation of brain α2-adrenoceptor and μ-opioid receptor densities during morphine dependence and spontaneous withdrawal in rats

J. García-Sevilla, L. Ugedo, I. Ulibarri, 1987, Naunyn-Schmiedeberg's Archives of Pharmacology.

Protection by imidazol(ine) drugs and agmatine of glutamate‐induced neurotoxicity in cultured cerebellar granule cells through blockade of NMDA receptor

G. Olmos, N. DeGregorio-Rocasolano, T. Gasull, 1999, British journal of pharmacology.

Up-regulated 14-3-3β and 14-3-3ζ proteins in prefrontal cortex of subjects with schizophrenia: effect of psychotropic treatment

J. García-Sevilla, B. Morentin, G. Rivero, 2015, Schizophrenia Research.

Disruption of brain MEK-ERK sequential phosphorylation and activation during midazolam-induced hypnosis in mice: Roles of GABAA receptor, MEK1 inactivation, and phosphatase MKP-3

M. Álvaro-Bartolomé, J. García-Sevilla, G. Salort, 2017, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Behavioral, neurochemical and morphological changes induced by the overexpression of munc18-1a in brain of mice: relevance to schizophrenia

J. Leza, M. Desco, J. Pascau, 2013, Translational Psychiatry.

Regulation of cannabinoid CB2 receptor constitutive activity in vivo: repeated treatments with inverse agonists reverse the acute activation of JNK and associated apoptotic signaling in mouse brain

M. Álvaro-Bartolomé, J. García-Sevilla, G. Salort, 2017, Psychopharmacology.

Attenuation of tolerance to opioid‐induced antinociception and protection against morphine‐induced decrease of neurofilament proteins by idazoxan and other I2‐imidazoline ligands

G. Olmos, J. García-Sevilla, M. A. Boronat, 1998, British journal of pharmacology.

The time course of unconditioned morphine-induced psychomotor sensitization mirrors the phosphorylation of FADD and MEK/ERK in rat striatum: Role of PEA-15 as a FADD-ERK binding partner in striatal plasticity

S. Esteban, J. García-Sevilla, A. Ramos-Miguel, 2010, European Neuropsychopharmacology.

Phosphorylation of FADD (Fas-associated death domain protein) at serine 194 is increased in the prefrontal cortex of opiate abusers: Relation to mitogen activated protein kinase, phosphoprotein enriched in astrocytes of 15 kDa, and Akt signaling pathways involved in neuroplasticity

J. García-Sevilla, L. Callado, J. Meana, 2009, Neuroscience.

The Fas Receptor/Fas-Associated Protein and Cocaine

M. Álvaro-Bartolomé, J. García-Sevilla, M. García-Fuster, 2016 .

Opioid receptor agonists enhance the phosphorylation state of Fas-associated death domain (FADD) protein in the rat brain: Functional interactions with casein kinase Iα, Gαi proteins, and ERK1/2 signaling

A. Miralles, J. García-Sevilla, M. García-Fuster, 2008, Neuropharmacology.

Disruption of cellular signaling pathways by daunomycin through destabilization of nonlamellar membrane structures.

P. Escribá, M. Sastre, J. García-Sevilla, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Labelling of human platelet α2-adrenoceptors with the full agonist [3H](−)adrenaline

J. García-Sevilla, M. J. Fuster, 1986 .

Alpha 2-adrenoceptor-mediated inhibition of platelet adenylate cyclase and induction of aggregation in major depression. Effect of long-term cyclic antidepressant drug treatment.

J. Guimón, D. Padro, J. García-Sevilla, 1990, Archives of general psychiatry.

α 2-Adrenoceptors in the brain of suicide victims: increased receptor density associated with major depression

J. García-Sevilla, J. Meana, F. Barturen, 1992, Biological Psychiatry.

Withdrawal from chronic ethanol increases the sensitivity of presynaptic 5-HT1A receptors modulating serotonin and dopamine synthesis in rat brain in vivo

S. Esteban, A. Miralles, D. Moranta, 2002, Neuroscience Letters.

Opiate‐receptor mediated changes in monoamine synthesis in rat brain

A. Carlsson, J. García-Sevilla, L. Ahtee, 1978, The Journal of pharmacy and pharmacology.

A Biomarker to Differentiate between Primary and Cocaine-Induced Major Depression in Cocaine Use Disorder: The Role of Platelet IRAS/Nischarin (I1-Imidazoline Receptor)

M. Farré, M. Torrens, M. Álvaro-Bartolomé, 2017, Front. Psychiatry.

Relationships between β- and α2-adrenoceptors and G coupling proteins in the human brain: effects of age and suicide

José Guimón, J. Guimón, M. Sastre, 2001, Brain Research.

Relationships between beta- and alpha2-adrenoceptors and G coupling proteins in the human brain: effects of age and suicide.

J. Guimón, M. Sastre, J. García-Sevilla, 2001, Brain research.

The neuroplastic index p-FADD/FADD and phosphoprotein PEA-15, interacting at GABAA receptor, are upregulated in brain cortex during midazolam-induced hypnosis in mice

M. Álvaro-Bartolomé, J. García-Sevilla, 2015, European Neuropsychopharmacology.

Decreased density and sensitivity of alpha 2-adrenoceptors in the brain of spontaneously hypertensive rats.

A. Miralles, G. Olmos, J. García-Sevilla, 1991, European journal of pharmacology.

μ-Opioid receptor and α2-adrenoceptor agonist stimulation of [35S]GTPγS binding to G-proteins in postmortem brains of opioid addicts

J. Guimón, J. González-Maeso, J. García-Sevilla, 2000, Molecular Psychiatry.

Chronic Effects of Cannabinoid Drugs on Monoaminergic Systems and the Role of Endocannabinoids and Cannabinoid Receptors in Human Brain Disorders

S. Esteban, M. Álvaro-Bartolomé, J. García-Sevilla, 2013 .

Effects induced by cannabinoids on monoaminergic systems in the brain and their implications for psychiatric disorders

S. Esteban, J. García-Sevilla, 2012, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Molecular adaptations of apoptotic pathways and signaling partners in the cerebral cortex of human cocaine addicts and cocaine-treated rats

M. Álvaro-Bartolomé, J. García-Sevilla, L. Callado, 2011, Neuroscience.

Immunodensity and mRNA expression of A2A adenosine, D2 dopamine, and CB1 cannabinoid receptors in postmortem frontal cortex of subjects with schizophrenia: effect of antipsychotic treatment

Rafael Franco, Vicent Casadó, Carmen Lluis, 2009, Psychopharmacology.

Neurofilament proteins and cAMP pathway in brains of μ-, δ- or κ-opioid receptor gene knock-out mice: effects of chronic morphine administration

R. Maldonado, B. Kieffer, J. García-Sevilla, 2004, Neuropharmacology.

G protein-coupled receptor kinases, beta-arrestin-2 and associated regulatory proteins in the human brain: postmortem changes, effect of age and subcellular distribution.

J. Guimón, J. García-Sevilla, C. Walzer, 2002, Brain research. Molecular brain research.

Regulation of cannabinoid CB1 and CB2 receptors, neuroprotective mTOR and pro-apoptotic JNK1/2 kinases in postmortem prefrontal cortex of subjects with major depressive disorder.

J. García-Sevilla, M. García-Fuster, G. Salort, 2020, Journal of affective disorders.

Increased mRNA Expression of α2A-Adrenoceptors, Serotonin Receptors and μ-Opioid Receptors in the Brains of Suicide Victims

P. Escribá, J. García-Sevilla, A. Ozaita, 2004, Neuropsychopharmacology.

Stimulation of mitogen-activated protein kinase kinases (MEK1/2) by μ-, δ- and κ-opioid receptor agonists in the rat brain: Regulation by chronic morphine and opioid withdrawal

A. Miralles, J. García-Sevilla, V. Asensio, 2006 .

Age-dependent increases in protein kinase C-αβ immunoreactivity and activity in the human brain: possible in vivo modulatory effects on guanine nucleotide regulatory Gi proteins

X. Busquets, M. Sastre, J. García-Sevilla, 1996, Brain Research.

Chronic treatment and withdrawal of the cannabinoid agonist WIN 55,212-2 modulate the sensitivity of presynaptic receptors involved in the regulation of monoamine syntheses in rat brain

S. Esteban, D. Moranta, J. García-Sevilla, 2008, Naunyn-Schmiedeberg's Archives of Pharmacology.

Behavioral and Cognitive Improvement Induced by Novel Imidazoline I2 Receptor Ligands in Female SAMP8 Mice

M. Pallàs, C. Escolano, B. Pérez, 2018, Neurotherapeutics.

Decreased cortical FADD protein is associated with clinical dementia and cognitive decline in an elderly community sample

S. Leurgans, D. Bennett, W. Honer, 2017, Molecular Neurodegeneration.

Neurotensin and its amide analogue [Gln4]-neurotensin: effects on brain monoamine turnover

A. Carlsson, J. Leban, K. Folkers, 1978, Naunyn-Schmiedeberg's Archives of Pharmacology.

Decreased immunodensities of micro-opioid receptors, receptor kinases GRK 2/6 and beta-arrestin-2 in postmortem brains of opiate addicts.

J. García-Sevilla, R. La Harpe, M. Ferrer-Alcón, 2004, Brain research. Molecular brain research.

Chronic clorgyline induces selective down-regulation of alpha2-adrenoceptor agonist binding sites in rat brain.

P. Escribá, A. Miralles, J. García-Sevilla, 2000, Pharmacology & toxicology.

Activation and desensitization by cyclic antidepressant drugs of α2-autoreceptors, α2-heteroreceptors and 5-HT1A-autoreceptors regulating monoamine synthesis in the rat brain in vivo

S. Esteban, J. García-Sevilla, A. Sastre-Coll, 1999, Naunyn-Schmiedeberg's Archives of Pharmacology.

The stimulatory effect of clonidine through imidazoline receptors on locus coeruleus noradrenergic neurones is mediated by excitatory amino acids and modulated by serotonin

J. García-Sevilla, J. Pineda, L. Ugedo, 1995, Naunyn-Schmiedeberg's Archives of Pharmacology.

Opposite effects of naloxone on substance P-induced changes in brain dopa synthesis and in locomotor activity in rats

A. Carlsson, J. García-Sevilla, T. Magnusson, 2005, Journal of Neural Transmission.

Pharmaceutical Specialties in the U.S.—A Note About the PDR 1972

J. García-Sevilla, S. Erill, P. Souich, 1974, Journal of clinical pharmacology.

Enhanced α2A‐autoreceptor reserve for clonidine induced by reserpine and cholinomimetic agents in the rat vas deferens

J. García-Sevilla, J. Pineda, L. Ugedo, 1997 .

Isothiocyanatobenzyl imidazoline is an alkylating agent for I2-imidazoline binding sites in rat and rabbit tissues

Duane D. Miller, G. Olmos, J. García-Sevilla, 1998, Naunyn-Schmiedeberg's Archives of Pharmacology.

5-HT2A receptor-mediated Gαq/11 activation in psychiatric disorders: A postmortem study

J. García-Sevilla, Y. Odagaki, L. Callado, 2020, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

μ-Opioid receptor and α2-adrenoceptor agonist binding sites in the postmortem brain of heroin addicts

M. Sastre, J. García-Sevilla, A. Gabilondo, 1994, Psychopharmacology.

Platelet α-adrenoceptors in heroin addicts during withdrawal and after treatment with clonidine

J. García-Sevilla, L. Ugedo, M. Gutiérrez, 1985 .

Pharmacologic Characterization of Imidazoline Receptor Proteins Identified by Immunologic Techniques and Other Methods a

P. Escribá, J. García-Sevilla, A. Ozaita, 1999, Annals of the New York Academy of Sciences.

Characterization and Regional Distribution of α2‐Adrenoceptors in Postmortem Human Brain Using the Full Agonist [3H]UK 14304

J. García-Sevilla, J. Meana, F. Barturen, 1989, Journal of neurochemistry.

Non-adrenoceptor [3H]idazoxan binding sites (I2-imidazoline sites) are increased in postmortem brain from patients with Alzheimer's disease

J. García-Sevilla, L. Callado, J. Meana, 1993, Neuroscience Letters.

Opposite Age‐Dependent Changes of α2A‐Adrenoceptors and Nonadrenoceptor [3H]Idazoxan Binding Sites (I2‐Imidazoline Sites) in the Human Brain: Strong Correlation of I2 with Monoamine Oxidase‐B Sites

M. Sastre, Magdalena Sastre, J. García-Sevilla, 1993, Journal of neurochemistry.

α2‐Adrenoceptor Subtypes Identified by [3H]RX821002 Binding in the Human Brain: The Agonist Guanoxabenz Does Not Discriminate Different Forms of the Predominant α2A Subtype

M. Sastre, J. García-Sevilla, 1994 .

The Stimulatory Effect of Clonidine on Locus Coeruleus Noradrenergic Neurons through Imidazoline Receptors Is Modulated by Excitatory Amino Acids fn1

J. García-Sevilla, J. Pineda, J. ANGEL RUIZ‐ORTEGA, 1995, Annals of the New York Academy of Sciences.

Repeated Idazoxan Increases Brain Imidazoline Receptors in Normotensive (WKY) but Not in Hypertensive (SHR) Rats

A. Miralles, G. Olmos, J. García-Sevilla, 1991, Journal of neurochemistry.

Supersensitivity of 5-HT1A-autoreceptors and α2-adrenoceptors regulating monoamine synthesis in the brain of morphine-dependent rats

S. Esteban, J. García-Sevilla, A. Sastre-Coll, 2002, Naunyn-Schmiedeberg's Archives of Pharmacology.

Acute and chronic effects of morphine and naloxone on the phosphorylation of neurofilament-H proteins in the rat brain

J. Guimón, J. García-Sevilla, P. Jaquet, 2001, Neuroscience Letters.

Regulation of nonphosphorylated and phosphorylated forms of neurofilament proteins in the prefrontal cortex of human opioid addicts

J. Guimón, B. Riederer, J. García-Sevilla, 2000, Journal of neuroscience research.

Modulation of immunoreactive protein kinase C-α and β isoforms and G proteins by acute and chronic treatments with morphine and other opiate drugs in rat brain

X. Busquets, J. García-Sevilla, P. Ventayol, 1997, Naunyn-Schmiedeberg's Archives of Pharmacology.

Attenuation of Tolerance to Opioid‐Induced Antinociception by Idazoxan and Other I2‐Ligands a

G. Olmos, J. García-Sevilla, M. A. Boronat, 1999, Annals of the New York Academy of Sciences.

Parallel modulation of receptor for activated C kinase 1 and protein kinase C‐α and β isoforms in brains of morphine‐treated rats

P. Escribá, J. García-Sevilla, 1999 .

Neurofilament proteins and cAMP pathway in brains of mu-, delta- or kappa-opioid receptor gene knock-out mice: effects of chronic morphine administration.

R. Maldonado, B. Kieffer, J. García-Sevilla, 2004, Neuropharmacology.

Induction of reactive astrocytosis and prevention of motoneuron cell death by the I2‐imidazoline receptor ligand LSL 60101

G. Olmos, J. García-Sevilla, A. Casanovas, 2000, British journal of pharmacology.

Cyclin-dependent kinase-5 and p35/p25 activators in schizophrenia and major depression prefrontal cortex: basal contents and effects of psychotropic medications.

J. García-Sevilla, J. Meana, A. Ramos-Miguel, 2013, The international journal of neuropsychopharmacology.

Regulation of munc18-1 and syntaxin-1A interactive partners in schizophrenia prefrontal cortex: down-regulation of munc18-1a isoform and 75 kDa SNARE complex after antipsychotic treatment.

J. García-Sevilla, J. Meana, L. Urigüen, 2012, The international journal of neuropsychopharmacology.

P.3.d.003 The cdk5 cofactor p35 is reduced in schizophrenia postmortem brains: downregulation of cdk5/p35/p25 after antipsychotic medication

J. García-Sevilla, J. Meana, A. Ramos-Miguel, 2011, European Neuropsychopharmacology.

Enhanced α2-adrenoceptor-mediated platelet aggregation in patients with major depressive disorder

J. Guimón, J. García-Sevilla, P. García-Vallejo, 1983 .

Tricyclic antidepressant drug treatment decreases alpha 2-adrenoreceptors on human platelet membranes.

A. Zis, C. Smith, J. García-Sevilla, 1981, European journal of pharmacology.

3H-clonidine and 3H-yohimbine bind to alpha2 receptors in human platelets

J. García-Sevilla, P. J. Hollingsworth, Charles B. Smith, 1980 .

Loss of high-affinity α 2-adrenoceptors in Alzheimer's disease: An autoradiographic study in frontal cortex and hippocampus

Á. Pazos, J. Zarranz, J. García-Sevilla, 1992, Neuroscience Letters.

Dysregulation of IRAS/nischarin and other potential I1-imidazoline receptors in major depression postmortem brain: Downregulation of basal contents by antidepressant drug treatments.

J. García-Sevilla, B. Keller, 2017, Journal of affective disorders.

Parallel modulation of receptor for activated C kinase 1 and protein kinase C-alpha and beta isoforms in brains of morphine-treated rats.

P. Escribá, J. García-Sevilla, 1999, British journal of pharmacology.

Ketamine-induced hypnosis and neuroplasticity in mice is associated with disrupted p-MEK/p-ERK sequential activation and sustained upregulation of survival p-FADD in brain cortex: Involvement of GABAA receptor

M. Álvaro-Bartolomé, J. García-Sevilla, G. Salort, 2019, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Effects of anti-depressant treatments on FADD and p-FADD protein in rat brain cortex: enhanced anti-apoptotic p-FADD/FADD ratio after chronic desipramine and fluoxetine administration

J. García-Sevilla, M. García-Fuster, 2016, Psychopharmacology.

Increased alpha 2-adrenoceptor density in the frontal cortex of depressed suicide victims.

J. García-Sevilla, J. Meana, 1987, Journal of neural transmission.

Increased α2- and β1-adrenoceptor densities in postmortem brain of subjects with depression: differential effect of antidepressant treatment.

J. García-Sevilla, G. Rivero, L. Callado, 2014, Journal of affective disorders.

Cyclic AMP-mediated signaling components are upregulated in the prefrontal cortex of depressed suicide victims

J. Guimón, T. Koyama, P. Huguelet, 2001, Brain Research.

Behavioral and Cognitive Improvement Induced by Novel Imidazoline I2 Receptor Ligands in Female SAMP8 Mice

M. Pallàs, C. Escolano, B. Pérez, 2018, Neurotherapeutics.

Substituting a long‐acting dopamine uptake inhibitor for cocaine prevents relapse to cocaine seeking

J. Canales, J. García-Sevilla, A. Ferragud, 2013, Addiction biology.

Effects of Age, Postmortem Delay and Storage Time on Receptor-mediated Activation of G-proteins in Human Brain

J. Guimón, J. González-Maeso, J. García-Sevilla, 2002, Neuropsychopharmacology.

Long‐term regulation of signalling components of adenylyl cyclase and mitogen‐activated protein kinase in the pre‐frontal cortex of human opiate addicts

J. García-Sevilla, R. La Harpe, M. Ferrer‐Alcón, 2004, Journal of neurochemistry.

Increased [3H] raclopride binding sites in postmortem brains from schizophrenic violent suicide victims

J. García-Sevilla, A. Gabilondo, J. Ruiz, 2005, Psychopharmacology.

Functional activation of Gαq coupled to 5-HT2A receptor and M1 muscarinic acetylcholine receptor in postmortem human cortical membranes

T. Ota, J. García-Sevilla, Y. Odagaki, 2017, Journal of Neural Transmission.

Loss of Protein Kinase C‐αβ in Brain of Heroin Addicts and Morphine‐Dependent Rats

P. Escribá, X. Busquets, M. Sastre, 1995 .

Pentobarbital and other anesthetic agents induce opposite regulations of MAP kinases p-MEK and p-ERK, and upregulate p-FADD/FADD neuroplastic index in brain during hypnotic states in mice

M. Álvaro-Bartolomé, J. García-Sevilla, G. Salort, 2019, Neurochemistry International.

Agonistic properties of a series of psychotropic drugs at 5-HT_1A receptors in rat and human brain membranes determined by [^35S]GTPγS binding assay

K. Fuxe, D. Borroto-Escuela, J. García-Sevilla, 2023, Pharmacological Reports.

FADD adaptor and PEA-15/ERK1/2 partners in major depression and schizophrenia postmortem brains: Basal contents and effects of psychotropic treatments

J. García-Sevilla, J. Meana, R. Harpe, 2014, Neuroscience.

Optimization and pharmacological characterization of receptor‐mediated Gi/o activation in postmortem human prefrontal cortex

T. Ota, J. García-Sevilla, Y. Odagaki, 2019, Basic & clinical pharmacology & toxicology.

α2-Adrenoceptor-mediated inhibition of platelet adenylate cyclase activity in heroin addicts in abstinence

J. García-Sevilla, L. Ugedo, M. Gutiérrez, 2004, Psychopharmacology.

Heroin increases the density and sensitivity of platelet α2-adrenoceptors in human addicts

J. García-Sevilla, L. Ugedo, M. Gutiérrez, 2004, Psychopharmacology.

Clinical response to clonidine and imipramine, and platelet alpha 2-adrenoreceptors in a case of agoraphobia with panic attacks.

O. Cameron, C. Smith, J. García-Sevilla, 1982, Biological Psychiatry.

Crosstalk between cdk5 and MEK–ERK signalling upon opioid receptor stimulation leads to upregulation of activator p25 and MEK1 inhibition in rat brain

J. García-Sevilla, A. Ramos-Miguel, 2012, Neuroscience.

Regulation of Cortico-Thalamic JNK1/2 and ERK1/2 MAPKs and Apoptosis-Related Signaling Pathways in PDYN Gene-Deficient Mice Following Acute and Chronic Mild Stress

J. Manzanares, T. Femenía, J. García-Sevilla, 2023, International Journal of Molecular Sciences.

Pharmacological and Immunological Characterization of Solubilized 130–140‐ and 66‐kD Imidazoline Receptors in the Rat Brain fn1

D. Reis, P. Escribá, A. Miralles, 1995, Annals of the New York Academy of Sciences.

Effects of constitutive deletion of opioid receptors on the basal densities of Fas and Fas-associated protein with death domain (FADD) in the mouse brain: A δ-opioid tone inhibits FADD

R. Maldonado, B. Kieffer, J. García-Sevilla, 2007, European Neuropsychopharmacology.

Effects of Imidazoline Drugs on Tyrosine and Tryptophan Hydroxylase Activity in Rat Brain in Vivo

S. Esteban, J. García-Sevilla, A. Sastre-Coll, 1999, Annals of the New York Academy of Sciences.

Lack of Effect of Reserpine on Immunoreactive Imidazoline Receptor Proteins in Rat Brain a

A. Miralles, J. García-Sevilla, A. Ozaita, 1999, Annals of the New York Academy of Sciences.

Reduced platelet G protein-coupled receptor kinase 2 in major depressive disorder: Antidepressant treatment-induced upregulation of GRK2 protein discriminates between responder and non-responder patients

D. Puigdemont, V. Pérez, E. Alvarez, 2010, European Neuropsychopharmacology.

Regulation of Platelet α2A-Adrenoceptors, Gi Proteins and Receptor Kinases in Major Depression: Effects of Mirtazapine Treatment

J. Guimón, D. Puigdemont, V. Pérez, 2004, Neuropsychopharmacology.

Effects of the I2‐Imidazoline Receptor Ligand LSL 60101 on Various Models of Anorexia in Rats fn1

J. García-Sevilla, À. Menargues, R. Obach, 1995, Annals of the New York Academy of Sciences.

Functional coupling of M1 muscarinic acetylcholine receptor to Gαq/11 in dorsolateral prefrontal cortex from patients with psychiatric disorders: a postmortem study

J. García-Sevilla, Y. Odagaki, L. Callado, 2019, European Archives of Psychiatry and Clinical Neuroscience.

Differential effects of acute cannabinoid drug treatment, mediated by CB1 receptors, on the in vivo activity of tyrosine and tryptophan hydroxylase in the rat brain

S. Esteban, D. Moranta, J. García-Sevilla, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Immunodetection and subcellular distribution of imidazoline receptor proteins with three antibodies in mouse and human brains: Effects of treatments with I1- and I2-imidazoline drugs

J. García-Sevilla, B. Keller, 2015, Journal of psychopharmacology.

Regulation of munc18-1 and syntaxin-1A interactive partners in schizophrenia prefrontal cortex: down-regulation of munc18-1a isoform and 75 kDa SNARE complex after antipsychotic treatment.

J. García-Sevilla, L. Urigüen, E. Munarriz-Cuezva, 2012, The international journal of neuropsychopharmacology.

Adenosine A1( )receptors are selectively coupled to Gα(i-3) in postmortem human brain cortex: Guanosine-5'-O-(3-[(35)S]thio)triphosphate ([(35)S]GTPγS) binding/immunoprecipitation study.

T. Ota, J. García-Sevilla, Y. Odagaki, 2015, European journal of pharmacology.

Effects induced by cannabinoids on monoaminergic systems in the brain and their implications for psychiatric disorders

S. Esteban, J. García-Sevilla, 2012, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

EFFECTS OF PEPTIDES ON BRAIN MONOAMINE METABOLISM AND ON GROSS BEHAVIOUR IN RATS

A. Carlsson, J. García-Sevilla, T. Magnusson, 1979 .

mu-Opioid receptor and alpha 2-adrenoceptor agonist binding sites in the postmortem brain of heroin addicts.

M. Sastre, J. García-Sevilla, J. Meana, 1994, Psychopharmacology.

mu-opioid receptor and alpha2-adrenoceptor agonist stimulation of [35S]GTPgammaS binding to G-proteins in postmortem brains of opioid addicts.

J. Guimón, J. González-Maeso, J. García-Sevilla, 2000, Molecular psychiatry.

Benzofuranyl-2-imidazoles as imidazoline I2 receptor ligands for Alzheimer's disease.

M. Loza, J. Brea, K. Nikolić, 2021, European journal of medicinal chemistry.