Xuwen Wang

发表

Importance of Incorporating Protein Flexibility in Molecule Modeling: A Theoretical Study on Type I1/2 NIK Inhibitors

Huidong Yu, Dan Li, Lei Xu, 2019, Frontiers in Pharmacology.

Reliability of Docking-Based Virtual Screening for GPCR Ligands with Homology Modeled Structures: A Case Study of the Angiotensin II Type I Receptor.

Dan Li, Tingjun Hou, Shan Chang, 2018, ACS chemical neuroscience.

Binding affinity and dissociation pathway predictions for a series of USP7 inhibitors with pyrimidinone scaffold by multiple computational methods.

Tingjun Hou, Zhe Wang, Dongsheng Cao, 2020, Physical chemistry chemical physics : PCCP.

farPPI: a webserver for accurate prediction of protein-ligand binding structures for small-molecule PPI inhibitors by MM/PB(GB)SA methods

Feng Zhu, Yu Kang, Tingjun Hou, 2018, Bioinform..

Discovery of a Novel Androgen Receptor Antagonist Manifesting Evidence to Disrupt the Dimerization of the Ligand-Binding Domain via Attenuating the Hydrogen-Bonding Network Between the Two Monomers.

Dan Li, Tingjun Hou, Mojie Duan, 2021, Journal of medicinal chemistry.

Advances in the computational development of androgen receptor antagonists.

Dan Li, Tingjun Hou, Mojie Duan, 2020, Drug discovery today.

Novel androgen receptor antagonist identified by structure-based virtual screening, structural optimization, and biological evaluation.

Dan Li, Tingjun Hou, Lei Xu, 2020, European journal of medicinal chemistry.

DNA methyltransferases: emerging targets for the discovery of inhibitors as potent anticancer drugs.

S. Zeng, Tingjun Hou, Zhe Wang, 2019, Drug discovery today.

Discovery of a novel nonsteroidal selective glucocorticoid receptor modulator by virtual screening and bioassays

Dan Li, Feng Zhu, Tingjun Hou, 2022, Acta Pharmacologica Sinica.

Exploring the prominent performance of CX-4945 derivatives as protein kinase CK2 inhibitors by a combined computational study.

Youyong Li, T. Hou, P. Pan, 2014, Molecular bioSystems.

Structure-Based Drug Design and Identification of H2O-Soluble and Low Toxic Hexacyclic Camptothecin Derivatives with Improved Efficacy in Cancer and Lethal Inflammation Models in Vivo.

Huidong Yu, Jean J. Zhao, Huiyong Sun, 2018, Journal of medicinal chemistry.

Drug discovery targeting anaplastic lymphoma kinase (ALK).

Youyong Li, Xiaotian Kong, Huiyong Sun, 2019, Journal of medicinal chemistry.

Discovery of Novel GR Ligands toward Druggable GR Antagonist Conformations Identified by MD Simulations and Markov State Model Analysis

Dan Li, Tingjun Hou, Mojie Duan, 2021, Advanced science.

Importance of a crystalline water network in docking-based virtual screening: a case study of BRD4.

Huanxiang Liu, Tingjun Hou, Hui Liu, 2019, Physical chemistry chemical physics : PCCP.

Communication between the Ligand-Binding Pocket and the Activation Function-2 Domain of Androgen Receptor Revealed by Molecular Dynamics Simulations

Tingjun Hou, Huiyong Sun, Youyong Li, 2019, J. Chem. Inf. Model..