A. Zweemer

发表

False positives in a reporter gene assay: identification and synthesis of substituted N-pyridin-2-ylbenzamides as competitive inhibitors of firefly luciferase.

A. IJzerman, L. Heitman, J. V. van Veldhoven, 2008, Journal of medicinal chemistry.

Multiple binding sites for small molecule antagonists at the chemokine receptor CCR2

A. IJzerman, L. Heitman, M. Doornbos, 2014 .

Multiple Binding Sites for Small-Molecule Antagonists at the CC Chemokine Receptor 2

A. IJzerman, H. de Vries, L. Heitman, 2013, Molecular Pharmacology.

A two‐state model for the kinetics of competitive radioligand binding

L. Peletier, A. IJzerman, H. de Vries, 2018, British journal of pharmacology.

Pyrrolone Derivatives as Intracellular Allosteric Modulators for Chemokine Receptors: Selective and Dual-Targeting Inhibitors of CC Chemokine Receptors 1 and 2

A. IJzerman, L. Heitman, J. V. van Veldhoven, 2018, Journal of medicinal chemistry.

Design and synthesis of novel small molecule CCR2 antagonists: evaluation of 4-aminopiperidine derivatives.

A. IJzerman, H. de Vries, L. Heitman, 2014, Bioorganic & medicinal chemistry letters.

Structure-Kinetics Relationships – an overlooked parameter in hit-to-lead optimization: a case of cyclopentylamines as CCR2 antagonists

A. Zweemer, Annelien J. M. Zweemer, 2014 .

Synthesis, binding affinity and structure-activity relationships of novel, selective and dual targeting CCR2 and CCR5 receptor antagonists.

L. Heitman, M. Schäfers, K. Kopka, 2015, Organic & biomolecular chemistry.

Synthesis and biological evaluation of spirocyclic antagonists of CCR2 (chemokine CC receptor subtype 2).

L. Heitman, B. Wünsch, Anna Junker, 2015, Bioorganic & medicinal chemistry.

Evaluation of (4‐Arylpiperidin‐1‐yl)cyclopentanecarboxamides As High‐Affinity and Long‐Residence‐Time Antagonists for the CCR2 Receptor

A. IJzerman, L. Heitman, J. Brussee, 2015, ChemMedChem.

Development of the First Potential Nonpeptidic Positron Emission Tomography Tracer for the Imaging of CCR2 Receptors

L. Heitman, K. Kopka, Nuska Tschammer, 2020, ChemMedChem.

When structure-affinity relationships meet structure-kinetics relationships: 3-((Inden-1-yl)amino)-1-isopropyl-cyclopentane-1-carboxamides as CCR2 antagonists.

A. IJzerman, H. de Vries, L. Heitman, 2015, European journal of medicinal chemistry.

Structure-kinetic relationships--an overlooked parameter in hit-to-lead optimization: a case of cyclopentylamines as chemokine receptor 2 antagonists.

John Saunders, Zhiyi Yu, Johannes Brussee, 2013, Journal of medicinal chemistry.

Bias in chemokine receptor signalling.

A. IJzerman, L. Heitman, A. Zweemer, 2014, Trends in immunology.

Apoptotic Bodies Elicit Gas6-Mediated Migration of AXL-Expressing Tumor Cells

Aaron S. Meyer, D. Lauffenburger, S. Gordonov, 2017, Molecular Cancer Research.

Survival Apoptotic Bodies Elicit Gas 6-Mediated Migration of AXL-Expressing Tumor Cells

Aaron S. Meyer, D. Lauffenburger, S. Gordonov, 2017 .

The AXL Receptor is a Sensor of Ligand Spatial Heterogeneity.

Aaron S. Meyer, D. Lauffenburger, A. Zweemer, 2015, Cell systems.

A series of 2,4-disubstituted quinolines as a new class of allosteric enhancers of the adenosine A3 receptor.

Thea Mulder-Krieger, Johannes Brussee, A. IJzerman, 2009, Journal of medicinal chemistry.

Discovery and Mapping of an Intracellular Antagonist Binding Site at the Chemokine Receptor CCR2

A. IJzerman, H. de Vries, L. Heitman, 2014, Molecular Pharmacology.

Functionally biased modulation of A(3) adenosine receptor agonist efficacy and potency by imidazoquinolinamine allosteric enhancers.

Kenneth A Jacobson, Kai Ye, K. Jacobson, 2011, Biochemical pharmacology.

The ins and outs of ligand binding to CCR2

A. Zweemer, Annelien J. M. Zweemer, 2014 .