Hiroko Koretsune

发表

TP0463518, a Novel Prolyl Hydroxylase Inhibitor, Specifically Induces Erythropoietin Production in the Liver

Sota Kato, Nagahiro Ochiai, Hiroki Takano, 2019, The Journal of Pharmacology and Experimental Therapeutics.

(4-Piperidinyl)-piperazine: a new platform for acetyl-CoA carboxylase inhibitors.

F. Io, Hiroko Koretsune, D. Yamamoto, 2009, Bioorganic & medicinal chemistry letters.

TP0463518, a novel inhibitor for hypoxia‐inducible factor prolyl hydroxylases, increases erythropoietin in rodents and monkeys with a good pharmacokinetics‐pharmacodynamics correlation

Sota Kato, Hiroki Takano, Noriko Takayama, 2018, European journal of pharmacology.

Discovery of novel 2-[(4-hydroxy-6-oxo-2,3-dihydro-1H-pyridine-5-carbonyl)amino]acetic acid derivatives as HIF prolyl hydroxylase inhibitors for treatment of renal anemia.

H. Kakinuma, Sota Kato, Hiroki Takano, 2018, Bioorganic & medicinal chemistry letters.

SGL5213, a novel and potent intestinal SGLT1 inhibitor, suppresses intestinal glucose absorption and enhances plasma GLP‐1 and GLP‐2 secretion in rats

F. Io, Hiroko Koretsune, Saeko Uchida, 2019, European journal of pharmacology.

Design and synthesis of disubstituted (4-piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase inhibitors.

F. Io, Hiroko Koretsune, D. Yamamoto, 2010, Bioorganic & medicinal chemistry letters.

Discovery of novel (4-piperidinyl)-piperazines as potent and orally active acetyl-CoA carboxylase 1/2 non-selective inhibitors: F-Boc and triF-Boc groups are acid-stable bioisosteres for the Boc group.

F. Io, Hiroko Koretsune, D. Yamamoto, 2011, Bioorganic & medicinal chemistry.

Discovery of Novel Pyrazolylpyridine Derivatives for 20-Hydroxyeicosatetraenoic Acid Synthase Inhibitors with Selective CYP4A11/4F2 Inhibition.

H. Kakinuma, Hiroko Koretsune, Yuji Ito, 2022, Journal of medicinal chemistry.

Design and synthesis of disubstituted (4-piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase inhibitors.

Hiroko Koretsune, D. Yamamoto, Akira Hiratate, 2010, Bioorganic & medicinal chemistry letters.

(4-Piperidinyl)-piperazine: a new platform for acetyl-CoA carboxylase inhibitors.

Hiroko Koretsune, D. Yamamoto, Akira Hiratate, 2009, Bioorganic & medicinal chemistry letters.