Y. Na

Yun‐Sil Lee, Y. Jin, Y. Na, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Oxiranylmethyloxy or thiiranylmethyloxy-azaxanthones and -acridone analogues as potential topoisomerase I inhibitors.

Y. Na, Youngjoo Kwon, M. Jung, 2009, Bioorganic & medicinal chemistry letters.

Synthesis of new xanthone analogues and their biological activity test--cytotoxicity, topoisomerase II inhibition, and DNA cross-linking study.

Y. Na, Youngjoo Kwon, Chong-soon Lee, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of C1-O-substituted-3-(3-butylamino-2-hydroxy-propoxy)-xanthen-9-one as topoisomerase IIα catalytic inhibitors.

Y. Na, Youngjoo Kwon, Kyu-Yeon Jun, 2016, European journal of medicinal chemistry.

Xanthone analogues as potent modulators of intestinal P-glycoprotein.

H. Lee, Y. Na, Youngjoo Kwon, 2015, European journal of medicinal chemistry.

Synthesis, biological evaluation, and molecular docking study of 3-(3'-heteroatom substituted-2'-hydroxy-1'-propyloxy) xanthone analogues as novel topoisomerase IIα catalytic inhibitor.

Y. Na, Youngjoo Kwon, Kyu-Yeon Jun, 2011, European journal of medicinal chemistry.

Synthesis and topoisomerase II inhibitory and cytotoxic activity of oxiranylmethoxy- and thiiranylmethoxy-chalcone derivatives.

Y. Na, J. Nam, 2011, Bioorganic & medicinal chemistry letters.

Synthesis and pharmacological evaluation of new methyloxiranylmethoxyxanthone analogues.

Y. Na, Youngjoo Kwon, Eun-Mi Ha, 2010, European journal of medicinal chemistry.

New benzoxanthone derivatives as topoisomerase inhibitors and DNA cross-linkers.

Y. Na, Youngjoo Kwon, M. Jung, 2010, Bioorganic & medicinal chemistry.

Design, synthesis, and evaluation of psorospermin/quinobenzoxazine hybrids as structurally novel antitumor agents.

L. Hurley, H. Vankayalapati, Mu-yong Kim, 2003, Journal of medicinal chemistry.

Design and synthesis of conformationally constrained hydroxylated 4-phenyl-2-aryl chromenopyridines as novel and selective topoisomerase II-targeted antiproliferative agents.

Y. Na, Youngjoo Kwon, Kyu-Yeon Jun, 2015, Bioorganic & medicinal chemistry.

A series of novel terpyridine-skeleton molecule derivants inhibit tumor growth and metastasis by targeting topoisomerases.

S. Rho, Y. Na, Youngjoo Kwon, 2015, Journal of medicinal chemistry.

Effect of chlorine substituent on cytotoxic activities: Design and synthesis of systematically modified 2,4-diphenyl-5H-indeno[1,2-b]pyridines.

Y. Na, Youngjoo Kwon, Kyu-Yeon Jun, 2016, Bioorganic & medicinal chemistry letters.

Study on the synthesis and cytotoxicity of new quinophenoxazine derivatives.

Y. Na, Youngjoo Kwon, 2006, Chemical & pharmaceutical bulletin.

Synthesis and investigation of dihydroxychalcones as calpain and cathepsin inhibitors.

Y. Na, Youngjoo Kwon, Eung-Seok Lee, 2013, Bioorganic chemistry.

Synthesis of 2-(thienyl-2-yl or -3-yl)-4-furyl-6-aryl pyridine derivatives and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship.

Y. Na, W. Cho, Youngjoo Kwon, 2010, Bioorganic & medicinal chemistry.

Topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of dihydroxylated 2,6-diphenyl-4-aryl pyridines.

Y. Na, Youngjoo Kwon, T. Kadayat, 2010, Bioorganic & medicinal chemistry.

Synthesis and Biological Properties of Luotonin a Derivatives

A. Rahman, Y. Na, Youngjoo Kwon, 2008 .

Recent cancer drug development with xanthone structures

Y. Na, 2009, The Journal of pharmacy and pharmacology.

SYNTHESIS AND BIOLOGICAL PROPERTIES OF SELECTED 2-ARYL-4(3H)-QUINAZOLINONES

Y. Na, Y. Jahng, J. Son, 2004 .

Design, synthesis, and antitumor evaluation of 2,4,6-triaryl pyridines containing chlorophenyl and phenolic moiety.

Y. Na, W. Cho, Youngjoo Kwon, 2012, European journal of medicinal chemistry.

Synthesis, Topoisomerase I and II Inhibitory Activity, Cytotoxicity, and Structure-activity Relationship Study of Rigid Analogues of 2,4,6-Trisubstituted Pyridine Containing 5,6-Dihydrobenzo(h)quinoline Moiety

Y. Na, Youngjoo Kwon, Eun-Mi Ha, 2011 .

Synthetic enantiopure aziridinomitosenes: preparation, reactivity, and DNA alkylation studies.

Don L. Warner, H. Kohn, Y. Na, 2003, Journal of the American Chemical Society.

2-Thienyl-4-furyl-6-aryl pyridine derivatives: synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study.

Y. Na, Youngjoo Kwon, Y. Jahng, 2010, Bioorganic & medicinal chemistry.

Synthesis and anti-melanogenic activity of hydroxyphenyl benzyl ether analogues.

Youngsoo Kim, Y. Na, Eun-Mi Ha, 2011, Bioorganic & medicinal chemistry.

Chalcones as Novel Non-peptidic μ-Calpain Inhibitors

Y. Na, Min-Jung Shin, Ji-Eun Eom, 2011 .

Intestinal P‐glycoprotein inhibitors, benzoxanthone analogues

H. Lee, Y. Na, J. Park, 2018, The Journal of pharmacy and pharmacology.

Drug-Like Small Molecule HSP27 Functional Inhibitor Sensitizes Lung Cancer Cells to Gefitinib or Cisplatin by Inducing Altered Cross-Linked Hsp27 Dimers

H. Lee, Yun‐Sil Lee, Y. Na, 2021, Pharmaceutics.

A-62176, a potent topoisomerase inhibitor, inhibits the expression of human epidermal growth factor receptor 2.

Yongmun Choi, Y. Na, Dae-Kee Kim, 2012, Cancer letters.

Calcium influx-mediated translocation of m-calpain induces Ku80 cleavage and enhances the Ku80-related DNA repair pathway

Eosu Kim, Y. Na, Han Yu, 2016, Oncotarget.

A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR study.

Y. Na, T. Kadayat, G. Bist, 2016, European journal of medicinal chemistry.

Sensitization of lung cancer cells by altered dimerization of HSP27

H. Lee, Yun‐Sil Lee, Y. Na, 2017, Oncotarget.

Synthesis and biological effect of chrom-4-one derivatives as functional inhibitors of heat shock protein 27.

Yun‐Sil Lee, Y. Na, S. Kwak, 2017, European journal of medicinal chemistry.

Design, synthesis, and biological evaluation of novel HSP27 inhibitors to sensitize lung cancer cells to clinically available anticancer agents.

Yun‐Sil Lee, Y. Na, Hawon Yoo, 2022, Bioorganic chemistry.

HSP27 inhibitor attenuates radiation-induced pulmonary inflammation

Yun‐Sil Lee, Jin-Mo Kim, Y. Na, 2018, Scientific Reports.

Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules

Yun‐Sil Lee, Y. Na, Naery Lee, 2016, Oncotarget.

Specific Roles of HSP27 S15 Phosphorylation Augmenting the Nuclear Function of HER2 to Promote Trastuzumab Resistance

Yun‐Sil Lee, S. Seo, Y. Na, 2020, Cancers.

2,4-Diaryl-5,6-dihydro-1,10-phenanthroline and 2,4-diaryl-5,6-dihydrothieno[2,3-h] quinoline derivatives for topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study.

P. Park, Y. Na, W. Cho, 2012, Bioorganic chemistry.

Chalcones, inhibitors for topoisomerase I and cathepsin B and L, as potential anti-cancer agents.

Y. Na, Seok-Ho Kim, Eung-Seok Lee, 2013, Bioorganic & medicinal chemistry letters.

Synthesis and topoisomerases inhibitory activity of heteroaromatic chalcones.

Y. Na, Han Yu, S. Kwak, 2016, Bioorganic & medicinal chemistry.

3-(3-Butylamino-2-hydroxy-propoxy)-1-hydroxy-xanthen-9-one acts as a topoisomerase IIα catalytic inhibitor with low DNA damage.

Y. Na, Eung-Seok Lee, Eunyoung Lee, 2013, European journal of medicinal chemistry.

Novel TGF‐β1 inhibitor antagonizes TGF‐β1‐induced epithelial‐mesenchymal transition in human A549 lung cancer cells

Kyung-Chul Choi, Y. Na, Ji-Hoon Jeong, 2018, Journal of cellular biochemistry.

Solvolysis study of cycliciminomitomycins.

Y. Na, 2007, Chemical and pharmaceutical bulletin.

Quinone-cyclized Porfiromycins

H. Kohn, Y. Na, 2001 .

Synthesis, DNA cross-linking activity, and cytotoxicity of dimeric mitomycins.

H. Kohn, Y. Na, Y. Nakanishi, 2001, Journal of Medicinal Chemistry.

A chromenone analog as an ATP-competitive, DNA non-intercalative topoisomerase II catalytic inhibitor with preferences toward the alpha isoform.

Y. Na, Hyunji Jo, Seojeong Park, 2019, Chemical communications.

Neuroprotective effect of synthetic chalcone derivatives as competitive dual inhibitors against μ-calpain and cathepsin B through the downregulation of tau phosphorylation and insoluble Aβ peptide formation.

Y. Na, Ji-Eun Eom, S. Kwak, 2016, European journal of medicinal chemistry.

Synthesis and biological evaluation of 2-phenol-4-chlorophenyl-6-aryl pyridines as topoisomerase II inhibitors and cytotoxic agents.

Y. Na, Pritam Thapa, T. Kadayat, 2016, Bioorganic chemistry.

Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor.

Kunhong Kim, Y. Na, S. Kim, 2014, Bioorganic & medicinal chemistry.

Novel Hypoxia-Inducible Factor 1α (HIF-1α) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy.

Chang Sik Cho, Jeeyeon Lee, Kyu-Won Kim, 2018, Journal of medicinal chemistry.

Effect of chlorine substituent on cytotoxic activities: Design and synthesis of systematically modified 2,4-diphenyl-5H-indeno[1,2-b]pyridines.

Y. Na, T. Kadayat, G. Bist, 2016, Bioorganic & medicinal chemistry letters.

Synthesis and biological effect of chrom-4-one derivatives as functional inhibitors of heat shock protein 27.

Yun‐Sil Lee, Y. Na, S. Kwak, 2017, European journal of medicinal chemistry.

Dithiiranylmethyloxy azaxanthone shows potent anti-tumor activity via suppression of HER2 expression and HER2-mediated signals in HER2-overexpressing breast cancer cells.

Yun‐Sil Lee, Y. Jin, Y. Na, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of hydroxylated 2,4-diphenyl-6-aryl pyridines.

T. Jeong, Y. Na, W. Cho, 2010, Bioorganic & medicinal chemistry.