L. Jia

发表

Long non-coding RNA UCA1 desensitizes breast cancer cells to trastuzumab by impeding miR-18a repression of Yes-associated protein 1.

A. Yang, Huayu Zhu, Wen-dong Bai, 2018, Biochemical and biophysical research communications.

MicroRNA-26a is a key regulon that inhibits progression and metastasis of c-Myc/EZH2 double high advanced hepatocellular carcinoma.

Ting Wang, Lei Wang, Xiang Zhang, 2018, Cancer letters.

Production and characterization of a recombinant single-chain antibody against Hantaan virus envelop glycoprotein

L. Yao, Yan Yan, Fang-lin Zhang, 2009, Applied Microbiology and Biotechnology.

MiR-221 promotes trastuzumab-resistance and metastasis in HER2-positive breast cancers by targeting PTEN

Lei Wang, Lintao Jia, Jing Zhao, 2014, BMB reports.

MicroRNA-139 suppresses proliferation in luminal type breast cancer cells by targeting Topoisomerase II alpha.

X. Zhang, A. Yang, L. Jia, 2015, Biochemical and biophysical research communications.

Targeted inhibition of hantavirus replication and intracranial pathogenesis by a chimeric protein‐delivered siRNA

A. Yang, L. Jia, Jie Yang, 2017, Antiviral research.

Potent inhibition of human gastric cancer by HER2-directed induction of apoptosis with anti-HER2 antibody and caspase-3 fusion protein

D. Fan, Li-Li Liu, Jie Liang, 2009, Gut.

protein anti-HER 2 antibody and caspase-3 fusion HER 2-directed induction of apoptosis with Potent inhibition of human gastric cancer

D. Fan, Li-Li Liu, Jie Liang, 2022 .

A survivin double point mutant has potent inhibitory effect on the growth of hepatocellular cancer cells

Jing Zhao, R. Chen, Tao Wang, 2008, Cancer biology & therapy.

Targeting and suppression of HER3-positive breast cancer by T lymphocytes expressing a heregulin chimeric antigen receptor

Wenjin Xi, A. Yang, L. Jia, 2018, Cancer Immunology, Immunotherapy.

Volume-sensitive outwardly rectifying chloride channel blockers protect against high glucose-induced apoptosis of cardiomyocytes via autophagy activation

L. Jia, M. Shen, Lin Wang, 2017, Scientific Reports.

Inhibition of Human Breast Cancer Cell Invasion by siRNA Against Urokinase-Type Plasminogen Activator

Tao Wang, J. Zhao, Zefei Jiang, 2010, Cancer investigation.

Tanshinone IIA and Astragaloside IV promote the angiogenesis of mesenchymal stem cell-derived endothelial cell-like cells via upregulation of Cx37, Cx40 and Cx43

Zong-ren Wang, L. Jia, Liang Cao, 2017, Experimental and therapeutic medicine.

Recombinant immunoproapoptotic proteins with furin site can translocate and kill HER2-positive cancer cells.

Tao Wang, A. Yang, L. Jia, 2007, Cancer research.

Selective proapoptotic activity of a secreted recombinant antibody/AIF fusion protein in carcinomas overexpressing HER2

D. Fan, A. Yang, X. Qiu, 2006, Gene Therapy.

Imaging and therapy of hSSTR2-transfected tumors using radiolabeled somatostatin analogs

J. Wang, Wei-dong Yang, Wen-hui Ma, 2013, Tumor Biology.

RNAi-mediated inhibition of presenilin 2 inhibits glioma cell growth and invasion and is involved in the regulation of Nrg1/ErbB signaling.

Hua Zhang, Chao Wang, Tao Wang, 2012, Neuro-oncology.

Single-chain antibody/activated BID chimeric protein effectively suppresses HER2-positive tumor growth

J. Zhao, A. Yang, X. Qiu, 2008, Molecular Cancer Therapeutics.

Roles of HLA-G/KIR2DL4 in Breast Cancer Immune Microenvironment

L. Jia, Guoxu Zheng, Anderson Yang, 2022, Frontiers in Immunology.

Identification of Juxtanodin promoter and its transcriptional regulation during the ATRA-induced differentiation of C6 cells

Guodong Yang, Shaoping Ji, L. Yao, 2011, Molecular and Cellular Biochemistry.

Molecular Insights into the Recruiting Between UCP2 and DDX5/UBAP2L in the Metabolic Plasticity of Non-Small-Cell Lung Cancer

Lei Zhang, Shengli Zhang, Zhiwei Yang, 2021, J. Chem. Inf. Model..

Hypoxia-sensitive long noncoding RNA CASC15 promotes lung tumorigenesis by regulating the SOX4/β-catenin axis

Tao Jiang, Tao Jiang, Kuo Jiang, 2020, Journal of experimental & clinical cancer research : CR.

HIV-TAT-fused FHIT protein functions as a potential pro-apoptotic molecule in hepatocellular carcinoma cells.

X. Zhang, Jing Zhao, A. Yang, 2012, Bioscience reports.

Knockdown of human bid gene expression enhances survival of CD8+ T cells.

Tao Wang, A. Yang, L. Jia, 2009, Immunology letters.

Specific tumoricidal activity of a secreted proapoptotic protein consisting of HER2 antibody and constitutively active caspase-3.

A. Yang, L. Jia, Si-Yi Chen, 2003, Cancer research.

Gastroenterological Cancer and Immunotherapy

Qi Chen, L. Jia, Xiaoping Wang, 2018, Canadian journal of gastroenterology & hepatology.

PTEN suppression promotes neurite development exclusively in differentiating PC12 cells via PI3‐kinase and MAP kinase signaling

Shaoping Ji, L. Jia, Xia Zhang, 2010, Journal of cellular biochemistry.

2 Targeted Apoptosis in Breast Cancer Immunotherapy

A. Yang, L. Jia, 2017 .

Targeted Apoptosis in Breast Cancer Immunotherapy

A. Yang, L. Jia, 2012 .

Subanesthetic isoflurane relieves zymosan-induced neutrophil inflammatory response by targeting NMDA glutamate receptor and Toll-like receptor 2 signaling

A. Yang, Ling Wang, L. Jia, 2016, Oncotarget.

Heat shock protein 70 silencing enhances apoptosis inducing factor-mediated cell death in hepatocellular carcinoma HepG2 cells

Jing Zhao, A. Yang, F. Wang, 2009, Cancer biology & therapy.

Cell Type-Specific and Inducible PTEN Gene Silencing by a Tetracycline Transcriptional Activator-Regulated Short Hairpin RNA

Tao Wang, L. Jia, Ting Wang, 2015, Molecules and cells.

HER2-targeting recombinant protein with truncated Pseudomonas Exotoxin: A translocation domain efficiently kills breast cancer cells

Tao Wang, Y. Duan, Jing Zhao, 2008, Cancer biology & therapy.

Ectopically Expressed Perforin-1 Is Proapoptotic in Tumor Cell Lines by Increasing Caspase-3 Activity and the Nuclear Translocation of Cytochrome c

Jing Zhao, A. Yang, F. Wang, 2012, PloS one.

Estrogen-induced dimerization and activation of ERα-fused caspase-8: Artificial reversal of the estrogenic hormone effect in carcinogenesis

Qiang Zhou, A. Yang, L. Jia, 2011, Cancer biology & therapy.

Post-Transcriptional Up-Regulation of PDGF-C by HuR in Advanced and Stressed Breast Cancer

Tao Wang, L. Jia, Guo-dong Yang, 2014, International journal of molecular sciences.

Ermin is a p116RIP‐interacting protein promoting oligodendroglial differentiation and myelin maintenance

Qian Yang, Lei Wang, L. Jia, 2020, Glia.

TFAP2A potentiates lung adenocarcinoma metastasis by a novel miR-16 family/TFAP2A/PSG9/TGF-β signaling pathway

Tao Jiang, Q. Lu, J. Lei, 2021, Cell Death & Disease.

Pseudogene OCT4-pg4 functions as a natural micro RNA sponge to regulate OCT4 expression by competing for miR-145 in hepatocellular carcinoma.

Rui Chen, Tao Wang, Lei Wang, 2013, Carcinogenesis.

Interaction between HLA-G and NK cell receptor KIR2DL4 orchestrates HER2-positive breast cancer resistance to trastuzumab

Weimiao Li, Wenjin Xi, A. Yang, 2021, Signal Transduction and Targeted Therapy.

Missing Links in Epithelial-Mesenchymal Transition: Long Non-Coding RNAs Enter the Arena

Fan Yang, Lei Wang, A. Yang, 2017, Cellular Physiology and Biochemistry.

MiR‐200c suppresses TGF‐β signaling and counteracts trastuzumab resistance and metastasis by targeting ZNF217 and ZEB1 in breast cancer

Wenjin Xi, A. Yang, Huayu Zhu, 2014, International journal of cancer.

An hepatitis B virus surface antigen specific single chain of variable fragment derived from a natural immune antigen binding fragment phage display library is specifically internalized by HepG2.2.15 cells

W. Qin, L. Jia, L. Yao, 2007, Journal of viral hepatitis.

Potential mechanisms of leukemia cell resistance to TRAIL-induced apopotosis

X. Hao, A. Newland, L. Jia, 2003, Apoptosis.

Potent killing of HBV-related hepatocellular carcinoma by a chimeric protein of anti-HBsAg single-chain antibody and truncated Bid.

Shuai Jiang, Tao Wang, Jing Zhao, 2013, Biomaterials.

Both Strands of siRNA Have Potential to Guide Posttranscriptional Gene Silencing in Mammalian Cells

Lin-Tao Jia, A. Yang, L. Jia, 2009, PloS one.

Regulators of carcinogenesis: emerging roles beyond their primary functions.

Lan Shen, A. Yang, L. Jia, 2015, Cancer letters.

Long non-coding RNAs AC026904.1 and UCA1: a “one-two punch” for TGF-β-induced SNAI2 activation and epithelial-mesenchymal transition in breast cancer

Hua Han, D. Fan, Wei Wang, 2018, Theranostics.

TGF-β Signaling Promotes Glioma Progression Through Stabilizing Sox9

Y. Tu, L. Jia, Nan Liu, 2021, Frontiers in Immunology.

CDK4/6 inhibition promotes immune infiltration in ovarian cancer and synergizes with PD-1 blockade in a B cell-dependent manner

Hong Yang, Kuo Jiang, Jia Li, 2020, Theranostics.

Caspase cleavage of Mcl-1 impairs its anti-apoptotic activity and proteasomal degradation in non-small lung cancer cells

Zhiwei Yang, Lei Wang, S. Zhang, 2017, Apoptosis.

Downregulation of NEDD4L by EGFR signaling promotes the development of lung adenocarcinoma

Jin Zhao, Liping Zhao, Changjing Wu, 2021, Journal of translational medicine.

Nuclear factor of activated T cells 5 maintained by Hotair suppression of miR-568 upregulates S100 calcium binding protein A4 to promote breast cancer metastasis

Tao Yang, Jing Zhao, Wei Li, 2014, Breast Cancer Research.

Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapy

Xiaofei Li, L. Jia, Yanlu Xiong, 2018, Cancer medicine.

HER2 interacts with CD44 to up-regulate CXCR4 via epigenetic silencing of microRNA-139 in gastric cancer cells.

Tao Wang, Qing Li, D. Fan, 2011, Gastroenterology.

Nkx2-2as Suppression Contributes to the Pathogenesis of Sonic Hedgehog Medulloblastoma.

Jing Zhao, A. Yang, Lei Wang, 2018, Cancer research.

Increase in the ratio of mitochondrial Bax/Bcl-XL induces Bax activation in human leukemic K562 cell line

A. Newland, L. Jia, Feng-Ting Liu, 2004, Apoptosis.

Activation of volume-sensitive outwardly rectifying chloride channel by ROS contributes to ER stress and cardiac contractile dysfunction: involvement of CHOP through Wnt

L. Wang, Y. Liu, L. Jia, 2014, Cell Death and Disease.

Sirtuin 3: A Janus face in cancer (Review).

L. Jia, Yanlu Xiong, Jinbo Zhao, 2016, International journal of oncology.

MiRNA-101 inhibits breast cancer growth and metastasis by targeting CX chemokine receptor 7

Xiu-li Wang, A. Yang, L. Jia, 2015, Oncotarget.

Human activated CD4(+) T lymphocytes increase IL-2 expression by downregulating microRNA-181c.

Tao Wang, Wei Li, A. Yang, 2011, Molecular immunology.

Cancer gene therapy targeting cellular apoptosis machinery.

A. Yang, L. Jia, Si-Yi Chen, 2012, Cancer treatment reviews.

A Caspase-6 and Anti-Human Epidermal Growth Factor Receptor-2 (HER2) Antibody Chimeric Molecule Suppresses the Growth of HER2-Overexpressing Tumors1

Rui Zhang, Jing Zhao, A. Yang, 2004, The Journal of Immunology.

HER 2-Overexpressing Tumors Chimeric Molecule Suppresses the Growth of Growth Factor Receptor-2 ( HER 2 ) Antibody A Caspase-6 and Anti-Human Epidermal

Jing Zhao, A. Yang, X. Qiu, 2004 .

Stable knockdown of estrogen receptor α by vector-based RNA interference suppresses proliferation and enhances apoptosis in breast cancer cells

Jing Zhao, A. Yang, L. Jia, 2006, Cancer biology & therapy.

MicroRNA-26a promotes anoikis in human hepatocellular carcinoma cells by targeting alpha5 integrin

N. Gammoh, Jing Zhao, A. Yang, 2014, Oncotarget.

TSA Suppresses miR-106b-93-25 Cluster Expression through Downregulation of MYC and Inhibits Proliferation and Induces Apoptosis in Human EMC

Qiang Zhou, Tao Wang, A. Yang, 2012, PloS one.

Uncoupling protein 2 downregulation by hypoxia through repression of peroxisome proliferator-activated receptor γ promotes chemoresistance of non-small cell lung cancer

Zhiwei Yang, S. Zhang, Lei Wang, 2016, Oncotarget.

SIRT3 deacetylates and promotes degradation of P53 in PTEN-defective non-small cell lung cancer

Xiaofei Li, Zhipei Zhang, Lei Wang, 2018, Journal of Cancer Research and Clinical Oncology.

Survivin stable knockdown by siRNA inhibits tumor cell growth and angiogenesis in breast and cervical cancers

Rui Zhang, Jing Zhao, A. Yang, 2006, Cancer biology & therapy.

Epigenetic silencing of miR-375 induces trastuzumab resistance in HER2-positive breast cancer by targeting IGF1R

Lei Wang, Huayu Zhu, Wen-dong Bai, 2014, BMC Cancer.

Long non-coding RNAs function as novel predictors and targets of non-small cell lung cancer: a systematic review and meta-analysis

Xiaofei Li, Zhipei Zhang, L. Jia, 2015, Oncotarget.

Deregulated miR‐155 promotes Fas‐mediated apoptosis in human intervertebral disc degeneration by targeting FADD and caspase‐3

Sheng-Xi Wu, Zhi-heng Liu, D. Samartzis, 2011, The Journal of pathology.

Noncoding RNAs in Therapeutic Resistance of Cancer.

L. Jia, A. Yang, 2016, Advances in experimental medicine and biology.

Identification of miRNA-7 by genome-wide analysis as a critical sensitizer for TRAIL-induced apoptosis in glioblastoma cells

Jing Zhao, Kaichun Wu, X. Zhang, 2017, Nucleic acids research.

Flexibility in metabolism bestows tenacious viability on cancer

Xiaofei Li, Lei Wang, L. Jia, 2018, Life sciences.

Xiaofei Li, Zhipei Zhang, Lei Wang, 2017, International journal of oncology.

TOPK promotes lung cancer resistance to EGFR tyrosine kinase inhibitors by phosphorylating and activating c-Jun

Y. Li, Zhiwei Yang, S. Zhang, 2016, Oncotarget.

MiR-200 c suppresses TGF-b signaling and counteracts trastuzumab resistance and metastasis by targeting ZNF 217 and ZEB 1 in breast cancer

Wenjin Xi, A. Yang, Huayu Zhu, 2014 .

Targeting ubiquitin-specific protease 22 suppresses growth and metastasis of anaplastic thyroid carcinoma

A. Yang, L. Jia, Haikou Tang, 2016, Oncotarget.

The effect of direct translocation across endosomes on the cytotoxicity of the recombinant protein e23sFv-Fdt-casp6 to HER2 positive gastric cancer cells.

Tao Wang, A. Yang, L. Jia, 2011, Biomaterials.

Secreted Antibody/Granzyme B Fusion Protein Stimulates Selective Killing of HER2-overexpressing Tumor Cells*

J. Zhao, A. Yang, L. Jia, 2004, Journal of Biological Chemistry.

The Progress in Immunoproapoptotin Molecules Targeting Tumor Cells

Tao Wang, A. Yang, L. Jia, 2013 .

c‐Myc‐mediated epigenetic silencing of MicroRNA‐101 contributes to dysregulation of multiple pathways in hepatocellular carcinoma

Jing Zhao, Tao Wang, K. Dou, 2014, Hepatology.

HER2-mediated upregulation of MMP-1 is involved in gastric cancer cell invasion.

Wei Li, A. Yang, L. Jia, 2010, Archives of biochemistry and biophysics.

IL‐12 immunotherapy of murine leukaemia: comparison of systemic versus gene modified cell therapy

J. Medin, C. Paige, L. Jia, 2009, Journal of cellular and molecular medicine.

Epigenetic silencing of miR-144/451a cluster contributes to HCC progression via paracrine HGF/MIF-mediated TAM remodeling

Jun-Long Zhao, L. Jia, Lei Liu, 2021, Molecular cancer.

The proapoptotic activity of C-terminal domain of apoptosis-inducing factor (AIF) is separated from its N-terminal.

T. Han, Wei Zhang, Jing Zhao, 2009, Biological research.

Computational identification of potential chemoprophylactic agents according to dynamic behavior of peroxisome proliferator-activated receptor gamma

L. Meng, Zhiwei Yang, L. Jia, 2020, RSC advances.

Sp1‐mediated epigenetic dysregulation dictates HDAC inhibitor susceptibility of HER2‐overexpressing breast cancer

Zhiwei Yang, S. Zhang, Lei Wang, 2019, International journal of cancer.

Synaptic Neurotransmission Depression in Ventral Tegmental Dopamine Neurons and Cannabinoid-Associated Addictive Learning

Zhengping Jia, Zhiqiang Liu, R. Monette, 2010, PloS one.

Tat-3L4F: A Novel Peptide for Treating Drug Addiction by Disrupting Interaction Between PTEN and 5-HT2C Receptor

L. Jia, Xia Zhang, Jean-Christian Maillet, 2011 .

Tamoxifen represses miR-200 microRNAs and promotes epithelial-to-mesenchymal transition by up-regulating c-Myc in endometrial carcinoma cell lines.

Tao Wang, D. Fan, A. Yang, 2013, Endocrinology.

Targeted inhibition of HBV gene expression by single‐chain antibody mediated small interfering RNA delivery

W. Qin, Tao Wang, A. Yang, 2007, Hepatology.

Inhibition of non-small cell lung cancer cell proliferation and tumor growth by vector-based small interfering RNAs targeting HER2/neu.

Tao Wang, Jian Zhang, A. Yang, 2009, Cancer letters.

RETRACTED ARTICLE: Nuclear factor of activated T cells 5 maintained by Hotair suppression of miR-568 upregulates S100 calcium binding protein A4 to promote breast cancer metastasis

Jing Zhao, T. Yang, Wei Li, 2014, Breast Cancer Research.

Epigenetic silencing of miR-375 induces trastuzumab resistance in HER2-positive breast cancer by targeting IGF1R

A. Yang, Lei Wang, Huayu Zhu, 2014, BMC Cancer.

miR-26a desensitizes non-small cell lung cancer cells to tyrosine kinase inhibitors by targeting PTPN13

Y. Li, Zhiwei Yang, S. Zhang, 2016, Oncotarget.

Human Ermin (hErmin), a new oligodendrocyte-specific cytoskeletal protein related to epileptic seizure

Fang Wang, Guodong Yang, L. Yao, 2011, Brain Research.

Glucocorticoid counteracts cellular mechanoresponses by LINC01569-dependent glucocorticoid receptor–mediated mRNA decay

K. Tao, D. Hu, Huayu Zhu, 2021, Science Advances.

RNA m6A reader IGF2BP3 promotes metastasis of triple‐negative breast cancer via SLIT2 repression

Xiao Zhang, L. Jia, Ting Wang, 2022, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The biological mechanism underpinning microRNA (miRNA) biogenesis allows for the understanding of the incorporation of short hairpin RNAs (shRNA) targeting genes of interest into natural miRNA backbones (BBmiR). Chimeric miRNA‐based shRNAs (shRNAmiR), driven by RNA polymerase II promoters, mimic pri

J. Zhao, L. Jia, Rui Zhang, 2017 .

An improved method for rapid preparation of oligodendrocyte-specific rabbit polyclonal antibody

L. Yao, F. Wang, L. Jia, 2011 .