Shuenn-Chen Yang

发表

p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug

Ker-Chau Li, Chung-Wu Lin, Wing-Kai Chan, 2009, Nature Cell Biology.

p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug

Ker-Chau Li, Chung-Wu Lin, Wing-Kai Chan, 2009, Nature Cell Biology.

The ability of LCRMP-1 to promote cancer invasion by enhancing filopodia formation is antagonized by CRMP-1.

Yih-Leong Chang, Chen‐Tu Wu, Yung‐Chie Lee, 2011, The Journal of clinical investigation.

Modulation of the expression of the invasion-suppressor CRMP-1 by cyclooxygenase-2 inhibition via reciprocal regulation of Sp1 and C/EBPα

Jeremy J. W. Chen, J. Shih, Pan‐Chyr Yang, 2008, Molecular Cancer Therapeutics.

Phenanthrene-based tylophorine-1 (PBT-1) inhibits lung cancer cell growth through the Akt and NF-kappaB pathways.

Hsuan-Yu Chen, Sung-Liang Yu, Pan‐Chyr Yang, 2009, Journal of medicinal chemistry.

Highly specific in vivo gene delivery for p53-mediated apoptosis and genetic photodynamic therapies of tumour

Pan‐Chyr Yang, Hsin-Jung Li, Z. Liao, 2015, Nature Communications.

Trifluoperazine, an antipsychotic agent, inhibits cancer stem cell growth and overcomes drug resistance of lung cancer.

Chi-Ying F. Huang, Yu-Lun Kuo, Chi-Ying F Huang, 2012, American journal of respiratory and critical care medicine.

Antitumor agents 295. E-ring hydroxylated antofine and cryptopleurine analogues as antiproliferative agents: design, synthesis, and mechanistic studies.

Pan‐Chyr Yang, C. Teng, S. Pan, 2012, Journal of medicinal chemistry.

Antitumor agents 288: design, synthesis, SAR, and biological studies of novel heteroatom-incorporated antofine and cryptopleurine analogues as potent and selective antitumor agents.

Sung-Liang Yu, Pan‐Chyr Yang, C. Teng, 2011, Journal of medicinal chemistry.

Antitumor agents 268. Design, synthesis, and mechanistic studies of new 9-substituted phenanthrene-based tylophorine analogues as potent cytotoxic agents.

Pan‐Chyr Yang, K. Lee, Guiyu Zhao, 2009, Journal of medicinal chemistry.

Collapsin response mediator protein-1: A novel invasion-suppressor gene

Chi-Ying F. Huang, J. Shih, Pan‐Chyr Yang, 2003, Clinical & Experimental Metastasis.

MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1

Yih-Leong Chang, Chen‐Tu Wu, Hsuan-Yu Chen, 2013, Nature Communications.

Overcoming EGFR T790M-based Tyrosine Kinase Inhibitor Resistance with an Allele-specific DNAzyme

K. Peck, Pan‐Chyr Yang, Jer-Yuarn Wu, 2014, Molecular therapy. Nucleic acids.

Small Molecule T315 Promotes Casitas B-Lineage Lymphoma-Dependent Degradation of Epidermal Growth Factor Receptor via Y1045 Autophosphorylation.

Jeremy J. W. Chen, Pan‐Chyr Yang, T. Hong, 2016, American journal of respiratory and critical care medicine.

Vorinostat combined with brigatinib overcomes acquired resistance in EGFR-C797S-mutated lung cancer.

Yih-Leong Chang, J. Shih, Pan‐Chyr Yang, 2021, Cancer letters.

Claudin-1 is a metastasis suppressor and correlates with clinical outcome in lung adenocarcinoma.

Sung-Liang Yu, Chung-Wu Lin, Yu-Chih Chao, 2009, American journal of respiratory and critical care medicine.

4(1H)-quinolone derivatives overcome acquired resistance to anti-microtubule agents by targeting the colchicine site of β-tubulin.

Chi‐Huey Wong, Pan‐Chyr Yang, T. Hong, 2019, European journal of medicinal chemistry.

Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvironment

S. Liang, Yi-Ching Wang, Chun-Ming Chen, 2017, The Journal of clinical investigation.

Tid1-L inhibits EGFR signaling in lung adenocarcinoma by enhancing EGFR Ubiquitinylation and degradation.

Yih-Leong Chang, Pan‐Chyr Yang, T. Hong, 2013, Cancer research.

Transcription Repressor Slug Promotes Carcinoma Invasion and Predicts Outcome of Patients with Lung Adenocarcinoma

Jeremy J. W. Chen, Yih-Leong Chang, J. Shih, 2005, Clinical Cancer Research.

Long form collapsin response mediator protein-1 (LCRMP-1) expression is associated with clinical outcome and lymph node metastasis in non-small cell lung cancer patients.

Yih-Leong Chang, Chen‐Tu Wu, Yung‐Chie Lee, 2010, Lung cancer.

Monocarboxylate Transporter 4 Is a Therapeutic Target in Non-small Cell Lung Cancer with Aerobic Glycolysis Preference

Yih-Leong Chang, Hsuan-Yu Chen, Pan‐Chyr Yang, 2020, Molecular therapy oncolytics.

The dual PI3K/mTOR inhibitor BEZ235 restricts the growth of lung cancer tumors regardless of EGFR status, as a potent accompanist in combined therapeutic regimens

T. Hong, C. Tsao, Shuenn-Chen Yang, 2019, Journal of experimental & clinical cancer research : CR.

Extracellular delivery of modified oligonucleotide and superparamagnetic iron oxide nanoparticles from a degradable hydrogel triggered by tumor acidosis.

Pan‐Chyr Yang, T. Hong, Ching-Wen Lin, 2013, Biomaterials.

Targeting Neuropilin 1 as an Antitumor Strategy in Lung Cancer

Wing-Kai Chan, Ang Yuan, Yu-Chih Chao, 2007, Clinical Cancer Research.

PM2.5 promotes lung cancer progression through activation of the AhR‐TMPRSS2‐IL18 pathway

Hsuan-Yu Chen, P-C. Yang, Chi-Yuan Chen, 2023, EMBO molecular medicine.

Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis

Hsuan-Yu Chen, T. Hong, T. Hsiao, 2016, Nature Communications.

Small-molecule PIK-93 modulates the tumor microenvironment to improve immune checkpoint blockade response

P-C. Yang, Shih-Han Kao, Shuenn-Chen Yang, 2023, Science advances.

MDA-9/Syntenin-Slug transcriptional complex promote epithelial-mesenchymal transition and invasion/metastasis in lung adenocarcinoma

Yih-Leong Chang, Chen‐Tu Wu, Pan‐Chyr Yang, 2015, Oncotarget.

PINK1-Mediated Inhibition of EGFR Dimerization and Activation Impedes EGFR-Driven Lung Tumorigenesis

Pan‐Chyr Yang, Shuenn-Chen Yang, Bo-tsang Huang, 2021, Cancer Research.

Integrated Omics Analysis of Non-Small-Cell Lung Cancer Cells Harboring the EGFR C797S Mutation Reveals the Potential of AXL as a Novel Therapeutic Target in TKI-Resistant Lung Cancer

Chi-Yuan Chen, Chih-Ching Wu, Tong-Hong Wang, 2020, Cancers.

The Antitumor Agent PBT-1 Directly Targets HSP90 and hnRNP A2/B1 and Inhibits Lung Adenocarcinoma Growth and Metastasis

Jau-Chen Lin, Chi-Yuan Chen, Pan‐Chyr Yang, 2014, Journal of medicinal chemistry.

Remote Control of Light-Triggered Virotherapy.

Pan‐Chyr Yang, Z. Liao, Shih-Han Kao, 2016, ACS nano.

Selection of invasive and metastatic subpopulations from a human lung adenocarcinoma cell line.

M. Hendrix, Y. Chu, S. C. Yang, 1997, American journal of respiratory cell and molecular biology.

Psorachromene induces apoptosis and suppresses tumor growth in NSCLC cells harboring EGFR L858R/T790M/C797S

Hsin-Jung Li, Chi-Yuan Chen, Tong-Hong Wang, 2022, Phytotherapy research : PTR.

Global analysis of gene expression in invasion by a lung cancer model.

J. Shih, J. J. Chen, Y. Sher, 2001, Cancer research.

The dual PI3K/mTOR inhibitor BEZ235 restricts the growth of lung cancer tumors regardless of EGFR status, as a potent accompanist in combined therapeutic regimens

T. Hong, C. Tsao, Shuenn-Chen Yang, 2019, Journal of Experimental & Clinical Cancer Research.

Collapsin response mediator protein-1 and the invasion and metastasis of cancer cells.

Yih-Leong Chang, J. Shih, J. J. Chen, 2001, Journal of the National Cancer Institute.

Phenanthrene-based tylophorine-1 (PBT-1) inhibits lung cancer cell growth through the Akt and NF-kappaB pathways.

Hsuan-Yu Chen, Sung-Liang Yu, Pan‐Chyr Yang, 2009, Journal of medicinal chemistry.

MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1

Yih-Leong Chang, Chen‐Tu Wu, Hsuan-Yu Chen, 2013, Nature Communications.