Gail M. Freiberg

发表

Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis.

Thomas R. Ioerger, Travis Hartman, Tom L. Blundell, 2017, ACS infectious diseases.

Bumped Kinase Inhibitors as therapy for apicomplexan parasitic diseases: lessons learned.

Dustin J Maly, D. Kempf, R. Hackman, 2020, International journal for parasitology.

Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis.

Dustin J Maly, W. Hol, M. Parsons, 2016, Journal of medicinal chemistry.

SAR Studies of 5-Aminopyrazole-4-carboxamide Analogues as Potent and Selective Inhibitors of Toxoplasma gondii CDPK1

Dustin J Maly, W. Hol, M. Parsons, 2015, ACS medicinal chemistry letters.

Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis.

Dustin J Maly, D. Kempf, Joachim Müller, 2017, International journal for parasitology.

Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based Drug Design.

Ana L. Aguirre, A. Hobson, K. Sarris, 2018, Journal of medicinal chemistry.

Design and evaluation of pyrazolopyrimidines as KCNQ channel modulators.

Gail M. Freiberg, Z. Wang, Jennifer A Van Camp, 2019, Bioorganic & medicinal chemistry letters.

A Thallium Transport FLIPR-Based Assay for the Identification of KCC2-Positive Modulators

C. Surowy, Gail M. Freiberg, S. Gopalakrishnan, 2010, Journal of biomolecular screening.

Spirocycle MmpL3 Inhibitors with Improved hERG and Cytotoxicity Profiles as Inhibitors of Mycobacterium tuberculosis Growth

A. Korkegian, L. Stojanovski, K. Read, 2021, ACS omega.

Characterization of novel rad6/ubc2 ubiquitin-conjugating enzyme mutants in yeast

A. Mesecar, S. Liebman, Gail M. Freiberg, 2000, Current Genetics.

Antimalarial Inhibitors Targeting Serine Hydroxymethyltransferase (SHMT) with in Vivo Efficacy and Analysis of their Binding Mode Based on X-ray Cocrystal Structures.

F. Diederich, R. Aponte, P. Chaiyen, 2017, Journal of medicinal chemistry.

Novel chemical entities inhibiting Mycobacterium tuberculosis growth identified by phenotypic high-throughput screening

A. Korkegian, D. Kempf, M. Files, 2022, Scientific Reports.

Utilization of Microarrayed Compound Screening (μARCS) to Identify Inhibitors of p56lck Tyrosine Kinase

Julie A. Wilkins, J. Kofron, U. Warrior, 2004, Journal of biomolecular screening.