D. Lees

发表

The differential contribution of tumour necrosis factor to thermal and mechanical hyperalgesia during chronic inflammation

S. Hunt, Y. Chernajovsky, B. Kidd, 2005, Arthritis research & therapy.

FAK-heterozygous mice display enhanced tumour angiogenesis

M. Parsons, Dylan T. Jones, I. Hart, 2013, Nature Communications.

203 Hypoxia-inducible Factor-1 Regulates Matrix Metalloproteinase-14 Expression: Underlying Effects of Hypoxia and Statins

F. Zhang, C. Hodgkinson, D. Lees, 2014, Heart.

Focal Adhesion Kinase (FAK) tyrosine 397E mutation restores the vascular leakage defect in endothelium‐specific FAK‐kinase dead mice

Natalia S. Bodrug, B. Serrels, D. Lees, 2017, The Journal of pathology.

The p55 tumor necrosis factor receptor (CD120a) induces endothelin-1 synthesis in endothelial and epithelial cells.

D. Lees, R. Corder, Z. Pallikaros, 2000, European journal of pharmacology.

Regulation of vascular endothelial function by procyanidin-rich foods and beverages.

E. Wood, T. Kanda, T. Shoji, 2010, Journal of agricultural and food chemistry.

Comparison of red wine extract and polyphenol constituents on endothelin-1 synthesis by cultured endothelial cells.

M. Carrier, D. Lees, J. Douthwaite, 2002, Clinical science.

Generation of point‐mutant FAK knockin mice

B. Serrels, D. Lees, A. Alexopoulou, 2014, Genesis.

Quantitative measurement of mRNA levels by RT-PCR. Studies of ECE-1 isoforms.

D. Lees, S. Barker, R. Corder, 2002, Methods in molecular biology.

Endothelin-2 synthesis is stimulated by the type-1 tumour necrosis factor receptor and cAMP: comparison with endothelin-converting enzyme-1 expression.

D. Lees, S. Barker, R. Corder, 2000, Journal of molecular endocrinology.

Existence of multiple isoforms of HS1-associated protein X-1 in murine and human tissues.

J. Marshall, I. Hart, D. Lees, 2008, Journal of molecular biology.

Homocysteine-Induced Endothelin-1 Release Is Dependent on Hyperglycaemia and Reactive Oxygen Species Production in Bovine Aortic Endothelial Cells

A. Dawnay, D. Lees, J. Douthwaite, 2006, Journal of Vascular Research.

Factor VIIa stimulates endothelin-1 synthesis in TNF-primed endothelial cells by activation of protease-activated receptor 2.

D. Lees, J. Douthwaite, R. Corder, 2005, Clinical science.

Inhibitory effect of adrenomedullin on basal and tumour necrosis factor alpha-stimulated endothelin-1 synthesis in bovine aortic endothelial cells is independent of cyclic AMP.

E. Wood, D. Lees, S. Barker, 2002, Biochemical pharmacology.

Health: Endothelin-1 synthesis reduced by red wine

Martin J. Carrier, Julie A. Douthwaite, M. Carrier, 2001, Nature.

Haematopoietic focal adhesion kinase deficiency alters haematopoietic homeostasis to drive tumour metastasis

T. Hagemann, G. Elia, C. L. Celso, 2014, Nature Communications.

Endothelial-cell FAK targeting sensitizes tumours to DNA-damaging therapy

J. Gribben, N. Perkins, G. Elia, 2014, Nature.

Stromal Claudin14-Heterozygosity, but Not Deletion, Increases Tumour Blood Leakage without Affecting Tumour Growth

G. Elia, M. Parsons, M. Baker, 2013, PloS one.

A role for increased mRNA stability in the induction of endothelin-1 synthesis by lipopolysaccharide.

D. Lees, J. Douthwaite, R. Corder, 2003, Biochemical pharmacology.

The procyanidin-induced pseudo laminar shear stress response: a new concept for the reversal of endothelial dysfunction.

E. Wood, D. Lees, R. Corder, 2004, Clinical science.

Phosphorylation of pericyte FAK-Y861 affects tumour cell apoptosis and tumour blood vessel regression

D. Lees, L. Reynolds, K. Hodivala-Dilke, 2020, Angiogenesis.

Elucidating the role of the kinase activity of endothelial cell focal adhesion kinase in angiocrine signalling and tumour growth

S. Duffy, V. Rajeeve, P. Cutillas, 2021, The Journal of pathology.

Tumor angiogenesis is differentially regulated by phosphorylation of endothelial cell focal adhesion kinase tyrosines-397 and -861.

M. Parsons, B. Serrels, D. Lees, 2019, Cancer research.

Relationship between soluble intracellular endothelin-converting enzyme and endothelin-1 synthesis: effect of inhibitors of the secretory pathway.

E. Wood, D. Lees, S. Barker, 2000, Journal of cardiovascular pharmacology.

Tumour vascular leakage defect due to endothelium-targeted FAK-kinase dead mutation is abrogated by FAK-Y397E expression

B. Serrels, D. Lees, A. Alexopoulou, 2017 .

Existence of multiple isoforms of HS1-associated protein X-1 in murine and human tissues.

J. Marshall, I. Hart, D. Lees, 2008, Journal of molecular biology.

Haematopoietic focal adhesion kinase deficiency alters haematopoietic homeostasis to drive tumour metastasis

T. Hagemann, G. Elia, C. L. Celso, 2014, Nature Communications.