K. Hamamura

发表

Bidirectional communication between sensory neurons and osteoblasts in an in vitro coculture system

H. Kondo, A. Togari, D. Kodama, 2017, FEBS letters.

RhoA-Mediated Signaling in Mechanotransduction of Osteoblasts

Hiroki Yokota, Sungsoo Na, Jiliang Li, 2012, Connective tissue research.

Suppression of osteoclastogenesis via α2-adrenergic receptors

H. Yokota, S. Goto, H. Kondo, 2018, Biomedical reports.

Sonic Hedgehog cDNA-plasmid Vector Transduction by Microbubble-Enhanced Sonoporation for Ectopic Bone Formation

M. Ueda, K. Hamamura, M. Shinoda, 2008 .

Positive feedback loop between PI3K-Akt-mTORC1 signaling and the lipogenic pathway boosts Akt signaling: induction of the lipogenic pathway by a melanoma antigen.

Kazuro Furukawa, Y. Yamauchi, K. Furukawa, 2011, Cancer research.

Enhancement of malignant properties of human osteosarcoma cells with disialyl gangliosides GD2/GD3

Kazuro Furukawa, K. Furukawa, K. Furukawa, 2012, Cancer science.

Overexpression of caveolin‐1 in a human melanoma cell line results in dispersion of ganglioside GD3 from lipid rafts and alteration of leading edges, leading to attenuation of malignant properties

I. Tohnai, K. Mitsudo, Kazuro Furukawa, 2007, Cancer science.

Suppression of osteoclastogenesis via upregulation of Zfyve21 and Ddit4 by salubrinal and guanabenz

H. Yokota, A. Togari, K. Hamamura, 2016 .

Potential therapeutic applications of salubrinal for skeletal diseases and beyond

H. Yokota, Y. Uto, K. Hamamura, 2015 .

Attenuation of malignant phenotypes of breast cancer cells through eIF2α-mediated downregulation of Rac1 signaling.

M. Koizumi, H. Yokota, N. Matsuura, 2014, International journal of oncology.

Salubrinal promotes healing of surgical wounds in rat femurs

H. Yokota, Ping Zhang, K. Hamamura, 2012, Journal of Bone and Mineral Metabolism.

pp-GalNAc-T13 induces high metastatic potential of murine Lewis lung cancer by generating trimeric Tn antigen.

Kazuro Furukawa, T. Urano, H. Nakada, 2012, Biochemical and biophysical research communications.

SSEA-3 and 4 are not essential for the induction or properties of mouse iPS cells.

Y. Murakumo, K. Furukawa, H. Hotta, 2020, Journal of oral science.

Orthodontic tooth movement-activated sensory neurons contribute to enhancing osteoclast activity and tooth movement through sympathetic nervous signalling.

Y. Ariji, E. Ariji, S. Goto, 2021, European journal of orthodontics.

Effects of Glucocorticoids on Diurnal Variations in Experimental Tooth Movement

S. Goto, H. Kondo, K. Miyazawa, 2020, Journal of Hard Tissue Biology.

Chondroprotective effects of Salubrinal in a mouse model of osteoarthritis

A. Sudo, H. Yokota, K. Hamamura, 2015, Bone & joint research.

Deficiency of GD3 Synthase in Mice Resulting in the Attenuation of Bone Loss with Aging

K. Furukawa, S. Goto, H. Kondo, 2019, International journal of molecular sciences.

ECM‐dependent mRNA expression profiles and phosphorylation patterns of p130Cas, FAK, ERK and p38 MAPK of osteoblast‐like cells

H. Yokota, K. Hamamura, Chang Jiang, 2010, Cell biology international.

Biosignals Modulated by Tumor‐Associated Carbohydrate Antigens

Kazuro Furukawa, K. Furukawa, K. Furukawa, 2006, Annals of the New York Academy of Sciences.

New era of research on cancer‐associated glycosphingolipids

Kazuro Furukawa, K. Furukawa, K. Hamamura, 2019, Cancer science.

Conditioned medium from rat dental pulp reduces the number of osteoclasts via attenuation of adhesiveness in osteoclast precursors.

S. Goto, H. Kondo, M. Honda, 2018, Journal of oral science.

Role of miR-222-3p in c-Src-Mediated Regulation of Osteoclastogenesis

A. Sudo, H. Yokota, S. Na, 2016, International journal of molecular sciences.

Ganglioside GD3 Enhances Adhesion Signals and Augments Malignant Properties of Melanoma Cells by Recruiting Integrins to Glycolipid-enriched Microdomains*

Kazuro Furukawa, Y. Yamauchi, K. Furukawa, 2010, The Journal of Biological Chemistry.

Molecules in the signaling pathway activated by gangliosides can be targets of therapeutics for malignant melanomas

Kazuro Furukawa, K. Furukawa, K. Furukawa, 2008, Proteomics.

Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells.

Kazuro Furukawa, J. Nakano, T. Urano, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Functional Activation of Src Family Kinase Yes Protein Is Essential for the Enhanced Malignant Properties of Human Melanoma Cells Expressing Ganglioside GD3*

Kazuro Furukawa, Y. Yamauchi, H. Hotta, 2011, The Journal of Biological Chemistry.

Signaling domains of cancer-associated glycolipids

Kazuro Furukawa, K. Furukawa, K. Hamamura, 2022, Glycoconjugate Journal.

Disialyl gangliosides enhance tumor phenotypes with differential modalities

Kazuro Furukawa, K. Furukawa, K. Furukawa, 2012, Glycoconjugate Journal.

GM1 / GD1b / GA1 synthase expression results in the reduced cancer phenotypes with modulation of composition and raft‐localization of gangliosides in a melanoma cell line

Kazuro Furukawa, K. Ikeda, R. Taguchi, 2010, Cancer science.

Lewis y Expressed in Oral Squamous Cell Carcinoma Attenuates Malignant Properties via Down-regulation of EGF Signaling

Kazuro Furukawa, K. Furukawa, K. Furukawa, 2021, AntiCancer Research.

α1B‐Adrenoceptor signalling regulates bone formation through the up‐regulation of CCAAT/enhancer‐binding protein δ expression in osteoblasts

H. Kondo, A. Togari, D. Kodama, 2016, British journal of pharmacology.

Differential roles of gangliosides in malignant properties of melanomas

Kazuro Furukawa, K. Furukawa, K. Furukawa, 2018, PloS one.

Involvement of p38 MAPK in regulation of MMP13 mRNA in chondrocytes in response to surviving stress to endoplasmic reticulum.

H. Yokota, M. Goldring, K. Hamamura, 2009, Archives of oral biology.

Salubrinal Acts as a Dusp2 Inhibitor and Suppresses Inflammation in Anti-Collagen Antibody-Induced Arthritis

A. Sudo, H. Yokota, K. Hamamura, 2015, Cellular signalling.

Attenuation of Bone Formation through a Decrease in Osteoblasts in Mutant Mice Lacking the GM2/GD2 Synthase Gene

Kazuro Furukawa, S. Goto, K. Miyazawa, 2022, International journal of molecular sciences.

Suppression of alveolar bone resorption by salubrinal in a mouse model of periodontal disease.

Y. Sugita, S. Goto, K. Miyazawa, 2021, Life sciences.

Focal adhesion kinase as well as p130Cas and paxillin is crucially involved in the enhanced malignant properties under expression of ganglioside GD3 in melanoma cells.

Kazuro Furukawa, T. Urano, K. Furukawa, 2008, Biochimica et biophysica acta.

Salubrinal reduces expression and activity of MMP13 in chondrocytes.

H. Yokota, K. Hamamura, Cc Lin, 2013, Osteoarthritis and cartilage.

Hydroxyapatite Modulates mRNA Expression Profiles in Cultured Osteocytes

H. Yokota, G. Swarnkar, K. Hamamura, 2012 .

Ganglioside GD2 Enhances the Malignant Phenotypes of Melanoma Cells by Cooperating with Integrins

Kazuro Furukawa, K. Honke, K. Furukawa, 2021, International journal of molecular sciences.

Essential roles of integrin-mediated signaling for the enhancement of malignant properties of melanomas based on the expression of GD3.

Kazuro Furukawa, K. Furukawa, K. Furukawa, 2008, Biochemical and biophysical research communications.

Hydroxyapatite Modulates mRNA Expression Profiles in Cultured Osteocytes

H. Yokota, G. Swarnkar, K. Hamamura, 2012, Cellular and Molecular Bioengineering.

Lewis y antigen is expressed in oral squamous cell carcinoma cell lines and tissues, but disappears in the invasive regions leading to the enhanced malignant properties irrespective of sialyl-Lewis x

Kazuro Furukawa, S. Toyokuni, K. Yamashita, 2013, Glycoconjugate Journal.

Mechanisms for the Apoptosis of Small Cell Lung Cancer Cells Induced by Anti-GD2 Monoclonal Antibodies

Shoko Yoshida, Kazunori Hamamura, Ryuzo Ueda, 2005, Journal of Biological Chemistry.

Knee loading reduces MMP13 activity in the mouse cartilage

H. Sun, H. Yokota, Ping Zhang, 2013, BMC Musculoskeletal Disorders.

Rac1 mediates load-driven attenuation of mRNA expression of nerve growth factor beta in cartilage and chondrocytes.

H. Yokota, S. Na, K. Hamamura, 2013, Journal of musculoskeletal & neuronal interactions.

IGF2‐driven PI3 kinase and TGFβ signaling pathways in chondrogenesis

H. Yokota, Ping Zhang, K. Hamamura, 2008, Cell biology international.

MSC Transplantation Improves Osteopenia via Epigenetic Regulation of Notch Signaling in Lupus.

S. Shi, Shiyu Liu, Chider Chen, 2015, Cell metabolism.

Model-based Comparative Prediction of Transcription-Factor Binding Motifs in Anabolic Responses in Bone

Yunlong Liu, Guohua Wang, Hiroki Yokota, 2008, Genom. Proteom. Bioinform..

Reduction in Migratory Phenotype in a Metastasized Breast Cancer Cell Line via Downregulation of S100A4 and GRM3

H. Nakshatri, K. Hamamura, Andy B. Chen, 2017, Scientific Reports.

Suppressed invasive and migratory behaviors of SW1353 chondrosarcoma cells through the regulation of Src, Rac1 GTPase, and MMP13.

H. Yokota, S. Na, K. Hamamura, 2015, Cellular signalling.

A therapeutic trial of human melanomas with combined small interfering RNAs targeting adaptor molecules p130Cas and paxillin activated under expression of ganglioside GD3.

Kazuro Furukawa, K. Hamamura, Y. Takei, 2016, Biochimica et biophysica acta.

eIF2α signaling regulates autophagy of osteoblasts and the development of osteoclasts in OVX mice

H. Yokota, Ping Zhang, S. Na, 2019, Cell Death & Disease.

A Brief Review of Bone Adaptation to Unloading

Ping Zhang, Hiroki Yokota, Kazunori Hamamura, 2008, Genom. Proteom. Bioinform..

Fine tuning of cell signals by glycosylation.

Y. Yamauchi, K. Furukawa, K. Furukawa, 2012, Journal of biochemistry.

GM1 expression in H-ras-transformed NIH3T3 results in the suppression of cell proliferation inducing the partial transfer of activated H-ras from non-raft to raft fraction.

T. Urano, K. Furukawa, K. Furukawa, 2005, International journal of oncology.

Guanabenz Downregulates Inflammatory Responses via eIF2α Dependent and Independent Signaling

A. Sudo, H. Yokota, K. Hamamura, 2016, International journal of molecular sciences.

Trimeric Tn Antigen on Syndecan 1 Produced by ppGalNAc-T13 Enhances Cancer Metastasis via a Complex Formation with Integrin α5β1 and Matrix Metalloproteinase 9*

Kazuro Furukawa, T. Urano, H. Nakada, 2013, The Journal of Biological Chemistry.

Salubrinal improves mechanical properties of the femur in osteogenesis imperfecta mice.

Joseph M. Wallace, A. Sudo, H. Yokota, 2016, Journal of pharmacological sciences.

In vitro and in silico analysis of an inhibitory mechanism of osteoclastogenesis by salubrinal and guanabenz.

A. Sudo, H. Yokota, K. Hamamura, 2015, Cellular signalling.

Effects of salubrinal on development of osteoclasts and osteoblasts from bone marrow-derived cells

H. Yokota, Ping Zhang, K. Hamamura, 2013, BMC Musculoskeletal Disorders.

Suppression of osteoclastogenesis through phosphorylation of eukaryotic translation initiation factor 2 alpha

H. Yokota, K. Hamamura, Nancy Tanjung, 2013, Journal of Bone and Mineral Metabolism.

Microarray analysis of thapsigargin — induced stress to the endoplasmic reticulum of mouse osteoblasts

H. Yokota, Yunlong Liu, K. Hamamura, 2008, Journal of Bone and Mineral Metabolism.

Stress to endoplasmic reticulum of mouse osteoblasts induces apoptosis and transcriptional activation for bone remodeling

H. Yokota, K. Hamamura, 2007, FEBS letters.

Disialyl gangliosides enhance tumor phenotypes with differential modalities

Kazuro Furukawa, K. Hamamura, Y. Ohkawa, 2012, Glycoconjugate Journal.

Potential Applications of Pulsating Joint Loading inSports Medicine

Ping Zhang, Hiroki Yokota, Kazunori Hamamura, 2009, Exercise and sport sciences reviews.

Attenuation of inflammatory arthritis through downregulating Dusp2 by salubrinal

H. Yokota, K. Hamamura, Andy B. Chen, 2015 .

Differential enhancing effects of alpha2,8-sialyltransferase on the cell proliferation and mobility.

Kazuro Furukawa, S. Fukumoto, K. Hamamura, 2005, International journal of oncology.

PEG attachment to osteoblasts enhances mechanosensitivity

H. Yokota, Jun Zhao, K. Hamamura, 2008, Biomedical materials.

Deletion of Gb3 Synthase in Mice Resulted in the Attenuation of Bone Formation via Decrease in Osteoblasts

M. Uchikawa, K. Furukawa, S. Goto, 2019, International journal of molecular sciences.

Glycosylation is involved in malignant properties of cancer cells

K. Furukawa, K. Hamamura, 2017 .

Proteomic analysis of ganglioside‐associated membrane molecules: Substantial basis for molecular clustering

Kazuro Furukawa, K. Honke, K. Hamamura, 2012, Proteomics.

Systemic administration of low-dose naltrexone increases bone mass due to blockade of opioid growth factor receptor signaling in mice osteoblasts.

H. Kondo, A. Togari, K. Hamamura, 2019, Life sciences.

Lengthening of mouse hindlimbs with joint loading

C. Turner, H. Yokota, Ping Zhang, 2010, Journal of Bone and Mineral Metabolism.

In Vitro and in Silico Analysis of ADAMTS5 Transcription in Human Chondrocytes

H. Sun, H. Yokota, K. Hamamura, 2013 .

Reduction in Migratory Phenotype in a Metastasized Breast Cancer Cell Line via Downregulation of S100A4 and GRM3

H. Nakshatri, H. Yokota, J. Ryu, 2017, Scientific Reports.

Predicting and validating the pathway of Wnt3a-driven suppression of osteoclastogenesis.

A. Sudo, H. Yokota, K. Hamamura, 2014, Cellular signalling.

Ganglioside GD 3 promotes cell growth and invasion through p 130 Cas and paxillin in malignant melanoma cells

J. Nakano, T. Urano, K. Furukawa, 2022 .

Enhancement of osteoblastogenesis and suppression of osteoclastogenesis by inhibition of de-phosphorylation of eukaryotic translation initiation factor 2 alpha.

H. Yokota, K. Hamamura, Andy B. Chen, 2015, Receptors & clinical investigation.

Lewis y antigen is expressed in oral squamous cell carcinoma cell lines and tissues, but disappears in the invasive regions leading to the enhanced malignant properties irrespective of sialyl-Lewis x

Kazuro Furukawa, S. Toyokuni, K. Yamashita, 2012, Glycoconjugate Journal.