J. Mort

F. Glorieux, J. Majewski, F. Rauch, 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Degradation of human proteoglycan aggregate induced by hydrogen peroxide. Protein fragmentation, amino acid modification and hyaluronic acid cleavage.

P. Roughley, J. Mort, C. Roberts, 1989, The Biochemical journal.

Structural basis for the recognition and cleavage of histone H3 by cathepsin L

Chao Xu, J. Min, Melanie A. Adams-Cioaba, 2011, Nature communications.

The occluding loop of cathepsin B prevents its effective inhibition by human kininogens.

C Naudin, E. Purisima, J. Krupa, 2010, Journal of molecular biology.

Cathepsin B.

D. Buttle, J. Mort, 1997, The international journal of biochemistry & cell biology.

Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion.

R. Coulombe, M. Cygler, P. Grochulski, 1996, Structure.

The Subterranean Crustacean Fauna of Castleguard Cave, Columbia Icefields, Alberta, Canada, and its Zoogeographic Significance∗

J. R. Holsinger, J. Mort, A. Recklies, 1983 .

Self Recognition in the Ig Superfamily

C. Stanners, J. Mort, A. Fuks, 2000 .

Activation of latent collagenase by serum proteinases that interact with immobilized immunoglobulin G

P. Roughley, A. Poole, J. Mort, 2004, Rheumatology International.

Displacement of the Occluding Loop by the Parasite Protein, Chagasin, Results in Efficient Inhibition of Human Cathepsin B*

Mariusz Jaskolski, Anna Ljunggren, M. Jaskólski, 2008, Journal of Biological Chemistry.

Cystatin inhibition of cathepsin B requires dislocation of the proteinase occluding loop. Demonstration by release of loop anchoring through mutation of His110

M. Abrahamson, I. Björk, J. Mort, 2000, FEBS letters.

Two‐step mechanism of inhibition of cathepsin B by cystatin C due to displacement of the proteinase occluding loop

M. Abrahamson, I. Björk, J. Mort, 1998, FEBS letters.

Mutations in WNT1 are a cause of osteogenesis imperfecta

F. Glorieux, J. Majewski, F. Rauch, 2013, Journal of Medical Genetics.

Cells from the skin of patients with systemic sclerosis secrete chitinase 3-like protein 1

M. Baron, P. Roughley, J. Mort, 2014, BBA clinical.

Studies on protein subunits. 3. Kinetic evidence for the presence of active subunits during the renaturation of muscle aldolase.

P. D. Macdonald, J. Mort, W. W. Chan, 1973, The Journal of biological chemistry.

Aggrecan heterogeneity in articular cartilage from patients with osteoarthritis

P. Roughley, J. Mort, W. Fisher, 2016, BMC Musculoskeletal Disorders.

Human articular cartilage secretes characteristic metal dependent proteinases upon stimulation by mononuclear cell factor.

P. Roughley, J. Mort, I. Campbell, 1986, The Journal of rheumatology.

Cartilage proteoglycan aggregate is degraded more extensively by cathepsin L than by cathepsin B.

P. Roughley, J. Mort, Q. Nguyen, 1990, The Biochemical journal.

Immunofluorescent localization of cathepsins B and D in human fibroblasts.

A. Poole, J. Mort, R. Decker, 1981, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Expression and Localization of Cathepsin K In Adult Rat Sertoli Cells1

L. Hermo, B. Zirkin, M. D. Anway, 2004, Biology of reproduction.

Antibodies to rat procathepsin B recognize the active mature enzyme.

J. Mort, L. Mach, A. D. Rowan, 1992, Biological chemistry Hoppe-Seyler.

Characterization of a cysteine proteinase secreted by mouse mammary gland.

J. Mort, A. Recklies, 1985, Cancer research.

A simple, economical method for staining gels for cathepsin B-like activity.

M. Leduc, J. Mort, John S. Mort, 1982, Analytical biochemistry.

Rat mammary gland in culture secretes a stable high molecular weight form of cathepsin L.

J. Mort, A. Recklies, 1985, Biochemical and biophysical research communications.

S′2 substrate specificity and the role of His110 and His111 in the exopeptidase activity of human cathepsin B

R. Ménard, J. Krupa, D. K. Nägler, 2002 .

S2' substrate specificity and the role of His110 and His111 in the exopeptidase activity of human cathepsin B.

R. Ménard, J. Krupa, D. K. Nägler, 2002, The Biochemical journal.

An NMR‐based identification of peptide fragments mimicking the interactions of the cathepsin B propeptide

W. Vranken, A. C. Storer, N. Goudreau, 1998, FEBS letters.

Aggrecan degradation in human intervertebral disc and articular cartilage.

P. Roughley, M. Alini, M Alini, 1997, The Biochemical journal.

Crystallization and preliminary x‐ray diffraction studies of human procathepsin L

R. Ménard, R. Coulombe, M. Cygler, 1996, Proteins.

The control of pyruvate kinase of Escherichia coli. Binding of substrate and allosteric effectors to the enzyme activated by fructose 1,6-bisphosphate.

E. Waygood, B. Sanwal, J. Mort, 1976, Biochemistry.

Differential changes in the association and dissociation rate constants for binding of cystatins to target proteinases occurring on N-terminal truncation of the inhibitors indicate that the interaction mechanism varies with different enzymes.

M. Abrahamson, E. Pol, I. Björk, 1994, The Biochemical journal.

The origin of human cartilage proteoglycan link-protein heterogeneity and fragmentation during aging.

P. Roughley, B. Caterson, J. Mort, 1985, The Biochemical journal.

The heterogeneity of link proteins isolated from human articular cartilage proteoglycan aggregates.

P. Roughley, J. Mort, A. Robin Poole, 1982, The Journal of biological chemistry.

Lysine-based Structure Responsible for Selective Mannose Phosphorylation of Cathepsin D and Cathepsin L Defines a Common Structural Motif for Lysosomal Enzyme Targeting*

K. Tao, G. Sahagian, M. Cygler, 1998, The Journal of Biological Chemistry.

Involvement of ADAMTS5 and hyaluronidase in aggrecan degradation and release from OSM-stimulated cartilage.

P. Roughley, H. Nagase, J. Mort, 2011, European cells & materials.

Ageing and the aggregating proteoglycans of human articular cartilage.

P. Roughley, J. Mort, 1986, Clinical science.

Reduction in Disease Progression by Inhibition of Transforming Growth Factor α–CCL2 Signaling in Experimental Posttraumatic Osteoarthritis

J. Mort, F. Beier, C. G. Appleton, 2015, Arthritis & rheumatology.

Enhanced denaturation of the α1(II) chains of type‐II collagen in normal adult human intervertebral discs compared with femoral articular cartilage

P. Roughley, A. Hollander, A. Poole, 1996, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Lack of tissue inhibitor of metalloproteinases-3 results in an enhanced inflammatory response in antigen-induced arthritis.

R. Khokha, J. Mort, D. Smookler, 2005, The American journal of pathology.

Subunit interactions in aspartate transcarbamylase. Characterization of a complex between the catalytic and the regulatory subunits.

J. Mort, W. W. Chan, 1975, The Journal of biological chemistry.

Secretion of a thiol proteinase from mouse mammary carcinomas and its characterization.

A. Poole, J. Mort, A. Recklies, 1982, Cancer research.

Negative Regulation of Epidermal Growth Factor Signaling by Selective Proteolytic Mechanisms in the Endosome Mediated by Cathepsin B*

A. Bell, J. Mort, M. Métioui, 1999, The Journal of Biological Chemistry.

Link Protein Has Greater Affinity for Versican than Aggrecan*

M. O’Connor-McCourt, P. Roughley, S. Shi, 2004, Journal of Biological Chemistry.

Rat procathepsin B. Proteolytic processing to the mature form in vitro.

J. Mort, L. Mach, A. D. Rowan, 1992, The Journal of biological chemistry.

Demonstration by electrospray mass spectrometry that the peptidyldipeptidase activity of cathepsin B is capable of rat cathepsin B C-terminal processing.

Y. Konishi, J. Mort, A. D. Rowan, 1993, The Biochemical journal.

Expression of rat and mouse cathepsin B precursors in Escherichia coli.

D. Steiner, S. Chan, J. Mort, 1988, Biological Chemistry Hoppe-Seyler.

Anabolic and catabolic markers of proteoglycan metabolism in osteoarthritis.

P. Roughley, B. Caterson, C. Hughes, 1995, Acta orthopaedica Scandinavica. Supplementum.

Chondroadherin Fragmentation Mediated by the Protease HTRA1 Distinguishes Human Intervertebral Disc Degeneration from Normal Aging*

P. Roughley, D. Heinegård, R. Gawri, 2013, The Journal of Biological Chemistry.

Expression and Localization of Cathepsin K In Adult Rat Sertoli Cells 1

L. Hermo, B. Zirkin, M. D. Anway, 2022 .

Investigation of structure function relationships in cathepsin B.

C. P. Huber, J. Mort, A. Muir, 1992, Biological chemistry Hoppe-Seyler.

Resolution of cartilage proteoglycan and its proteolytic degradation products by high-performance liquid chromatography using a gel filtration system.

P. Roughley, J. Mort, 1985, Analytical biochemistry.

Modulation of the catabolic effects of interleukin-1 beta on human articular chondrocytes by transforming growth factor-beta.

J. Mort, B. E. Hakala, A. Recklies, 1996, Journal of cellular physiology.

Crystallization of recombinant rat cathepsin B.

C. P. Huber, D. Rose, J. Mort, 1990, The Journal of biological chemistry.

Crystal structure of the parasite protease inhibitor chagasin in complex with a host target cysteine protease.

M. Jaskólski, M. Abrahamson, G. Bujacz, 2007, Journal of molecular biology.

Link protein as a monitor in situ of endogenous proteolysis in adult human articular cartilage.

P. Roughley, J. Mort, Q. Nguyen, 1991, The Biochemical journal.

Efficient processing of procathepsin K to the mature form.

J. Mort, A. Emmott, 2013, Protein expression and purification.

Cathepsin B: an alternative protease for the generation of an aggrecan 'metalloproteinase' cleavage neoepitope.

J. Mort, Eunice R. Lee, M. Magny, 1998, Biochemical Journal.

Neoepitopes reveal the features of type II collagen cleavage and the identity of a collagenase involved in the transformation of the epiphyses anlagen in development

C. P. Leblond, J. Mort, Eunice R. Lee, 2009, Developmental dynamics : an official publication of the American Association of Anatomists.

Osteoporosis Caused by Mutations in PLS3: Clinical and Bone Tissue Characteristics

F. Glorieux, J. Majewski, F. Rauch, 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Cartilage link proteins. Biochemical and immunochemical studies of isolation and heterogeneity.

V. Hascall, L. Tang, J. Kimura, 1984, The Journal of biological chemistry.

Mononuclear cell factor modulates the concomitant release of proteoglycan and latent proteinase by human articular cartilage in organ culture.

P. Roughley, J. Mort, I. Campbell, 1986, Agents and actions. Supplements.